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Allogeneic bone marrow transplantation in pancytopenia (363477) | University Hospital Essen - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align: justify;\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align: justify;\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.<\/p>\n\n<p style=\"text-align: justify;\">When your complete blood count returns to normal, your doctor will schedule your <strong>discharge from the department<\/strong>. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Bone marrow biopsy results (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>case history collection<\/li>\n\t<li>general clinical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>differential blood count<\/li>\n\t\t<li>inflammation indicators (CRP, ESR)<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>CT\/MRI scans&nbsp;of the whole body<\/li>\n\t<li>needle biopsy of the bone marrow<\/li>\n\t<li>biopsy and histological examination of&nbsp;CSF<\/li>\n\t<li>examination by&nbsp;experts of:\n\t<ul>\n\t\t<li>cardiology<\/li>\n\t\t<li>otolaryngology<\/li>\n\t\t<li>immunology<\/li>\n\t\t<li>ophthalmology<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>registration in the European bone marrow donor base<\/li>\n\t<li>conducting high-dose chemotherapy<\/li>\n\t<li>allogeneic bone marrow transplantation from<br \/>\n\tunrelated donor<\/li>\n\t<li>the cost of blood products<\/li>\n\t<li>isolation by neutropenic precautions<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>control examinations<\/li>\n\t<li>the cost of essential medicines and materials<\/li>\n\t<li>nursing services<\/li>\n\t<li>full hospital accommodation<\/li>\n\t<li>explanation of future recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\"><strong>During the first visit<\/strong>, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align: justify;\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align: justify;\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. 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Allogeneic bone marrow transplantation in pancytopenia

University Hospital Essen

Essen, Germany
Program id # 363477
Doctor photo
Prof. Dr. med. Dietrich W. Beelen
Department of Bone Marrow Transplantation
Specialized in: bone marrow transplantation

The program includes:

  • Initial presentation in the clinic
  • case history collection
  • general clinical examination
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • differential blood count
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • CT/MRI scans of the whole body
  • needle biopsy of the bone marrow
  • biopsy and histological examination of CSF
  • examination by experts of:
    • cardiology
    • otolaryngology
    • immunology
    • ophthalmology
  • registration in the European bone marrow donor base
  • conducting high-dose chemotherapy
  • allogeneic bone marrow transplantation from
    unrelated donor
  • the cost of blood products
  • isolation by neutropenic precautions
  • symptomatic treatment
  • control examinations
  • the cost of essential medicines and materials
  • nursing services
  • full hospital accommodation
  • explanation of future recommendations

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.

Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.

Before the procedure, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.

The bone marrow transplant procedure is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.

During the period of healthy bone marrow engraftment, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.

A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.

When your complete blood count returns to normal, your doctor will schedule your discharge from the department. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.

Required documents

  • Medical records
  • Bone marrow biopsy results (if available)

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About the department

The Department of Bone Marrow Transplantation at the University Hospital Essen offers the full range of treatment for malignant and benign hematological diseases, diseases of the bone marrow and the lymphatic system. The department specializes in the treatment of acute and chronic leukemia, myelodysplastic syndrome, malignant lymphomas, multiple myeloma and aplastic syndrome. The department is the largest specialized center for allogeneic stem cell transplantation from related and unrelated donors in Europe. The Chief Physician of the department is a leading hematologist and oncologist, Prof. Dr. med. Dietrich W. Beelen.

The Chief Physician of the department, Prof. Beelen, made a significant contribution to the development of allogeneic stem cell transplantation. In particular, he developed new, sparing methods for elderly patients in whom hematopoietic and lymphatic diseases are more common than in other age groups. In addition, the professor is also actively developing modified stem cell drugs for allogeneic transplantation in patients in the absence of tissue compatibility with the donor, as well as innovative cellular therapeutic drugs.

The department specializes in allogeneic stem cell transplantations for malignant and benign hematological systemic diseases. The specialists’ tasks also include the transplantation of the patient’s own hematopoietic stem cells after myeloablative or previous chemoradiation therapy of reduced intensity. The department has special competence in the field of allogeneic stem cell transplantation from a related donor with partial tissue compatibility or from an unrelated donor.

In addition, the department has at its disposal the specialized center for the production of stem cell drugs from the bone marrow and blood, which has at its command all the methods of collecting, preparing and storing hematopoietic stem cells. The department also operates the Transplant Coordination Center, which is responsible for optimizing the organizational processes associated with stem cell transplantation. Thus, thanks to the use of innovative medical technologies and the expertise of the medical staff, the department provides top-class medical services for stem cells transplantation.

The department’s range of medical services includes:

  • Allogeneic and autologous stem cell transplantation in the treatment of malignant and benign hematological systemic diseases:
    • Bone marrow cancer
    • Non-Hodgkin diffuse lymphoma
    • Diseases of the bone marrow with impaired hematopoietic function (myelodysplastic syndrome)
    • Blood cancer
    • And other diseases
  • Monitoring and management of patients after stem cell transplantation
  • Preparation of stem cell drugs from bone marrow and blood (specialized functional section)
  • Transplant Coordination Center
  • And other diagnostic and therapeutic options

Curriculum vitae

Current position

  • Since 2002 Head of the Department of Bone Marrow Transplantation at the University Hospital Essen.

Prizes and Awards

  • Numerous awards for achievements in the field of bone marrow transplantation.
  • 2014 Karl Heinrich Bauer Medal for special services in the field of bone marrow transplantation.

Research Focuses

  • Studies on the optimization of treatments for leukemia, lymphoma, and multiple myeloma.
  • Development and trials of new methods in conditioning therapy (including new cytostatics, radioimmunotherapy, helical tomotherapy).
  • Allogeneic stem cell transplants in older patients.
  • Allogeneic stem cell transplants with partially identical donors.
  • Optimization of donor selection.
  • Methods of transplant modification.
  • Adoptive cell therapy following allogeneic stem cell transplants.
  • Importance of molecular polymorphisms of congenital and acquired immunity in allogeneic stem cell transplants.
  • Detection and therapy of molecular residual disease following allogeneic stem cell transplants.

Photo of the doctor: (c) Universitätsklinikum Essen 


About hospital

According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals!

With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 employees takes care of the health of patients. All the specialists give preference to an interdisciplinary medical care, which guarantees a comprehensive treatment taking into account the smallest aspects of a particular pathology. The hospital annually diagnoses and treats more than 50,000 inpatients and about 195,000 outpatients, which testifies to the prestige of the medical institution and the highest quality of treatment in Germany.

The hospital presents all the modern medical fields. Nevertheless, special attention should be given to the following major fields of specialization as oncology, transplantology and cardiology, as well as research activities in the field of immunology, infectology and translational examinations of pathologies of the nervous system and behavioral disorders.

Established on the basis of the standard American model of Comprehensive Cancer Centers, the West German Cancer Center (WTZ) in Essen was recognized as the best medical facility of this kind in Germany in 2009. Nowadays, the center holds leading positions both on the national and international medical markets. The basis of its successful clinical practice is the use of very latest treatment methods and an interdisciplinary approach to each clinical case. The West German Organ Transplant Centre (WZO) is also recognized as one of the best in the country and one of the few in Germany, which specializes in the transplantation of all vital organs, such as kidney, liver, pancreas, heart and lungs. Special attention is paid to kidney and liver transplantation.

The hospital in Germany is proud of its high-tech medical equipment, experienced and competent staff, productive research activities, which allow to guarantee the accurate diagnostics and effective treatment, including rare and very complex clinical cases for every patient. Consequently, the hospital is considered a perfect embodiment of high-quality treatment in Germany.

Photo: (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital Essen live in comfortable rooms designed in bright colors. The standard room furnishing includes an automatically adjustable bed, a bedside table, a personal wardrobe, a personal call button with a built-in light panel, a telephone, a TV and a radio. The Internet access is available at an additional cost.

Meals and Menus

The patients of the hospital are offered a daily choice of three menus. The patients are also offered alternative types of menus, if their religion requires the exclusion of certain foods. If you follow a certain diet or suffer from food intolerance, you will be provided with a menu of your choice by discussing it with your attending physician in advance. The hospital also houses a bistro and a cafe, where one can have a tasty snack, enjoy hot and cold drinks.

Further details

Standard rooms include:

Toilet
Shower
TV

Accompanying person

There are a few types of hotels for the accompanying persons, who want to stay near the hospital. The hotel of the Essen University Hospital offers apartments on the first floor of the nursing high-rise building. The DRK nursing also offers single and double rooms.

The hotel in Grugapark is available for the parents, whose children stay in the hospital. The parents of children with cancer can also stay here. Moreover, The Department of Pediatrics offers its rooms for parents.