Hematology: Idiopathic thrombocytopenic purpura — Diagnosis and symptomatic therapy. Treatment
Idiopathic thrombocytopenic purpura (or thrombocytopenic purpura) is a hematological disease, which occurs due to destruction of platelets by own immune system. A typical sign of the disease is spontaneous bleeding under the skin and mucous membranes. In most cases, the condition is chronic and cannot be cured completely, but the proper treatment allows favorable prognosis for life of the patients.
To confirm the diagnosis, the hematologist’s advice is required. The physician holds a clinical examination, collects the case history and assigns a set of required studies:
- complete blood count,
- blood chemistry,
- Blood coagulation test,
- abdominal ultrasound,
- integrated CT/MRI,
- bone marrow aspiration biopsy (trepanobiopsy of the ilium wing).
During diagnostics, the thrombocytopenic purpura is distinguished from the other similar diseases (hemophilia, vasculitis, acute leukemia).
The treatment program is selected based on severity of the patient's condition. During exacerbations, the transfusion therapy is practiced. To restore the normal blood patients, the patients under the transfusions of blood or platelet mass. To reduce bleeding, the corticosteroid agents are prescribe. For frequent relapses, the use of immunosuppressive drugs is considering.
At the discretion of the physician, the treatment is carried out in hospital or outpatient setting. The further tactics is discussed individually in each case.Hide
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