Hematology: Pancytopenia — Stem cell transplantation. Treatment
Pancytopenia appears as a critical decrease in the level of all blood cells and can result from a variety of diseases and conditions, i.e. hereditary diseases of the hematopoietic system function, debilitating viral and bacterial infections, intensive radio- or chemotherapy of malignant tumors. In severe cases of pancytopenia, when the state of hematopoiesis is life-threatening, and there is no possibility to restore the bone marrow function by conservative method, the physicians resort to transplantation of the donor’s blood stem cell.
Upon admission to the hospital the patient will undergo an examination and tell his/her case history. To clarify the diagnosis and determine the indications for bone marrow transplantation, the general clinical and special examination is carried out:
- complete blood count and urinalysis;
- blood chemistry;
- ultrasound, CT and MRI – according to indications to clarify the status of the viscera and for differential diagnostics;
- bone marrow puncture and (or) iliac region punch biopsy.
Bone marrow transplantation takes place in five steps.
- Donor selection: to determine the donor compatibility, a series of laboratory tests is carried out.
- Collection of hematopoietic stem cells by bone marrow puncture or taking blood from the vein after a special preparation of the donor.
- Patient preparation: the immunosuppressants are commonly used to prevent transplant rejection.
- Donor cell transplantation: the material is slowly injected into the patient’s vein.
- Recovery time: the patient is placed in the special conditions, receives symptomatic therapy and drugs to prevent the transplantation complications. At this stage, the services of the qualified nursing staff are very important.
Stem cell transplantation requires that the patient stayed in the clinic full time for up to 30 days. The cost of required medicines must be confirmed by the attending physician.
The patient is discharged after stabilization and receipt of further recommendations on the lifestyle and outpatient treatment.Hide
Haven't found Your diagnosis yet?
Send an inquiry to get a cost estimate on: