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Surgery: Neuroblastoma (Ganglioneuroblastoma)

Neuroblastoma is a malignant tumor growing from cells of the sympathetic nervous system. This abnormality is usually detected in children 1 to 5 years old. After that threshold, the incidence rate is reduced significantly. Theoretically, neuroblastoma may develop in any part of the body, but it is commonly located in the abdomen, chest and neck. When choosing a treatment method, the physician takes into account not only the tumor parameters, but also the patient's risk group.

Low-Risk Group

Low-risk patients usually undergo surgical removal of the tumor only. Thereafter, the child is followed up by the oncologist. In rare cases, surgery is replaced by chemotherapy.

In infants, the spontaneous cure is possible, so they are sometimes subjected to simple observation. If the tumor begins to progress, the need for surgery is considered.

Medium (Intermediate) Risk Group

Such patients are treated comprehensively. In addition to surgical techniques, the chemotherapy and/or radiation therapy is used.

For an inoperable tumor, the chemotherapy is a primary recommendation. Administration of cytotoxic drugs reduces neuroblastoma size, allowing for its partial or complete removal. The modern treatment protocols include platinum drugs, vinca alkaloids, epipodophylotoxins, topoisomerase inhibitors, etc. Antibiotics are selected for prevention of infectious complications.

After tumor removal, radiotherapy or repeated chemotherapy is prescribed. This approach allows destroying the remnants of the cancer cells in the body and prevent the relapse.

High-Risk Group

Children at high risk are prescribed radical surgery, followed by the high-dose chemotherapy. As the intense effect of cytotoxic drugs leads to suppression of the stem cells functions, the autologous bone marrow transplantation must be conducted.

Biotherapy is often used to prevent the relapses. The patients are usually prescribed 13-cis-retinoic acid, stimulating the normal maturation of nerve cells. Drug treatment takes several months.

Subject to a proper treatment selection, the likelihood of overcoming the neuroblastomas is generally high. The best prognosis is seen in children from the medium and intermediate risk groups, where the number of cured patients reaches 70 to 90%.

 

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Academic Hospital Sachsenhausen Frankfurt am Main

10/10 from23 Votes
location_onGermany, Frankfurt am Main

Department of Surgery, Endocrine Surgery, Bariatric Surgery, Orthopedics, Traumatology

Resection of Neuroblastoma (ganglioneyroblastoma) #334059

The Department of Surgery annually performs more than 320 surgical resections of neuroblastoma (ganglioneuroblastoma). Interdisciplinary cooperation with other departments allows combining surgery with other treatments (chemotherapy).The specialists of the department under the direction of Prof. Dr. med. P. Staikov pay special attention to a thorough tissue histological examination after surgical resection of the tumor.

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HELIOS Clinic Krefeld

9.7/10 from38 Votes
location_onGermany, Krefeld

Department of of General, Abdominal and Minimally Invasive Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #388019

The Department of General, Abdominal and Minimally Invasive Surgery offers the full range of services in these medical fields. The department specializes in the surgical treatment of abdominal organs: esophagus, stomach, small and large intestine, liver, pancreas, gallbladder and bile ducts, thyroid gland.

University Hospital Rechts der Isar of the Munich Technical University

10/10 from70 Votes
location_onGermany, Munich
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Department of Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #212967

The Department of Surgery at the university hospital Klinikum rechts der Isar provides a wide range of treatment of diseases requiring surgical intervention.

St. Vincentius Clinic Karlsruhe

9.8/10 from23 Votes
location_onGermany, Karlsruhe

Department of General, Abdominal and Vascular Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #335915

The Department of General, Abdominal and Vascular Surgery at the St. Vincentius Clinic offers the entire range of relevant services at the highest level. Along with intestinal and thyroid surgeries, the most important areas of the department are minimally invasive (laparoscopic) and oncological surgery.

Academic Hospital Bogenhausen Munich

9.2/10 from43 Votes
location_onGermany, Munich
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Department of General, Abdominal, Endocrine and Minimally Invasive Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #204025

Beside general surgical primary care, the department of general, abdominal, endocrine and minimally invasive surgery has two specific medical emphases: visceral surgery and endocrine surgery. A separate focus of the department is on the surgery of abdominal oncological diseases.

Academic Hospital Neuperlach Munich

9.8/10 from11 Votes
location_onGermany, Munich
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Department of General and Abdominal Surgery, Endocrine Surgery and Coloproctology

Resection of Neuroblastoma (ganglioneyroblastoma) #204509

The department of general and abdominal surgery, endocrine surgery and coloprotology treats patients with surgical diseases of the organs of the abdominal cavity, the abdominal wall, and treated the anal region and endocrine organs (thyroid, parathyroid and adrenal glands).

Academic Hospital Schwabing Munich

8.5/10 from7 Votes
location_onGermany, Munich

Department of Abdominal Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #204643

The Department of Abdominal Surgery in Schwabing diagnoses and treats all kinds of diseases of the organs of the abdominal cavity - conservative, interventional and surgical. Here gastroenterologists, hepatologists and visceral surgeons work hand in hand and guarantee the patient an optimal, interdisciplinary care.

Hospital St. Elisabeth Grevenbroich

10/10 from23 Votes
location_onGermany, Grevenbroich
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Department of General, Visceral, Vascular Surgery and Traumatology

Resection of Neuroblastoma (ganglioneyroblastoma) #300730

The Department of General, Abdominal, Vascular Surgery and Traumatology at the Hospital St. Elisabeth Grevenbroich specializes in abdominal and vascular surgery, as well as in the treatment of victims of accidents.

Academic Hospital Asklepios Barmbek Hamburg

9.5/10 from23 Votes
location_onGermany, Hamburg

Department of General, Abdominal Surgery and Surgical Oncology

Resection of Neuroblastoma (ganglioneyroblastoma) #356586

The Department of General, Abdominal Surgery and Surgical Oncology offers the full range of services in these medical focuses. The department provides high-quality surgical treatment of all abdominal diseases. The surgeons of the department have a huge experience in performing open and laparoscopic interventions.

University Hospital Frankfurt am Main

10/10 from97 Votes
location_onGermany, Frankfurt am Main
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Department of General and Abdominal Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #210675

According to the Focus magazine rating of 2017, the Department of General and Abdominal Surgery ranks among the top German departments specializing in colon cancer treatment! The department deals with the treatment of all general and abdominal surgical diseases and performs surgery to transplant liv...

University Hospital Muenster

9.8/10 from78 Votes
location_onGermany, Muenster
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Department of General and Abdominal Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #204913

The Department of General and Abdominal Surgery at the University Hospital Muenster ranks among large university surgery centers of Germany. The Department specializes in the treatment of gastrointestinal malignancies (gastrointestinal tract) as well as hormone-producing (endocrine) organs.

University Hospital Würzburg

9.2/10 from38 Votes
location_onGermany, Würzburg
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Department of General, Abdominal, Vascular and Pediatric Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #223733

The Department of General, Abdominal, Vascular and Pediatric Surgery (Department of Surgery I) covers the entire spectrum of general and abdominal surgery. There are two specialized Sections of Vascular and Pediatric Surgery. The Department offers the whole range of top-class surgical services.

Hannover Medical School

9.8/10 from43 Votes
location_onGermany, Hannover
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Department of General, Abdominal and Transplant Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #245003

The Department of General, Abdominal and Transplant Surgery offers the full range of services in these medical fields.

Vivantes Neukölln Hospital Berlin

10/10 from23 Votes
location_onGermany, Berlin

Department of Minimally Invasive Surgery and Abdominal Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #362460

The Department of Minimally Invasive Surgery and Abdominal Surgery offers the full spectrum of surgical treatment of all internal diseases. One of the main focuses of the department is the treatment of cancer.

Tel Aviv Sourasky Medical Center

9.9/10 from23 Votes
location_onIsrael, Tel Aviv

Department of General Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #330203

The Department of General Surgery at the Tel Aviv Sourasky Medical Center treats patients requiring both emergent and planned surgery. The Department leads Israel in a broad range of surgical procedures and shows outstanding success rates.

University Hospital Cologne

9.8/10 from82 Votes
location_onGermany, Cologne
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Department of General, Abdominal and Tumor Surgery

Resection of Neuroblastoma (ganglioneyroblastoma) #210993

The Department of General, Abdominal and Tumor Surgery deals with the surgical treatment of benign and malignant diseases. The focus is on surgery to treat  cancer of the esophagus, stomach, small and large intestine, liver, gallbladder, pancreatic and thyroid cancer.




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