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Allogeneic bone marrow transplantation (stem cell transplant) in thalassemia (167677) | University Hospital RWTH Aachen - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align:justify\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align:justify\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align:justify\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align:justify\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align:justify\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.<\/p>\n\n<p style=\"text-align:justify\">When your complete blood count returns to normal, your doctor will schedule your <strong>discharge from the department.<\/strong> You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Complete blood count (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>case history collection<\/li>\n\t<li>general clinical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>general urine analysis<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>tumor markers<\/li>\n\t\t<li>indicators of inflammation<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>CT\/MRI scans&nbsp;of the whole body<\/li>\n\t<li>needle biopsy of the bone marrow<\/li>\n\t<li>biopsy and histological examination of&nbsp;CSF<\/li>\n\t<li>examination by&nbsp;experts of:\n\t<ul>\n\t\t<li>Cardiology<\/li>\n\t\t<li>Otolaryngology<\/li>\n\t\t<li>Immunology<\/li>\n\t\t<li>Ophthalmology<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>registration in the european bone marrow donor base<\/li>\n\t<li>conducting high-dose chemotherapy<\/li>\n\t<li>allogeneic bone marrow transplantation from<br \/>\n\tunrelated donor<\/li>\n\t<li>isolation by neutropenic precautions<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>the cost of essential medicines and&nbsp;blood products<\/li>\n\t<li>nursing services<\/li>\n\t<li>stay in the hospital with full board<\/li>\n\t<li>full hospital accommodation<\/li>\n\t<li>elaboration&nbsp;further recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align:justify\"><strong>During the first visit<\/strong>, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. 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Allogeneic bone marrow transplantation (stem cell transplant) in thalassemia

University Hospital RWTH Aachen

Aachen, Germany
Program id # 167677
Doctor photo
Prof. Dr. med. Norbert Wagner
Department of Pediatric and Adolescent Medicine
Specialized in: pediatric and adolescent medicine

The program includes:

  • Initial presentation in the clinic
  • case history collection
  • general clinical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers
    • indicators of inflammation
    • indicators of blood coagulation
  • CT/MRI scans of the whole body
  • needle biopsy of the bone marrow
  • biopsy and histological examination of CSF
  • examination by experts of:
    • Cardiology
    • Otolaryngology
    • Immunology
    • Ophthalmology
  • registration in the european bone marrow donor base
  • conducting high-dose chemotherapy
  • allogeneic bone marrow transplantation from
    unrelated donor
  • isolation by neutropenic precautions
  • symptomatic treatment
  • the cost of essential medicines and blood products
  • nursing services
  • stay in the hospital with full board
  • full hospital accommodation
  • elaboration further recommendations

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.

Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.

Before the procedure, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.

The bone marrow transplant procedure is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.

During the period of healthy bone marrow engraftment, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.

A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.

When your complete blood count returns to normal, your doctor will schedule your discharge from the department. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.

Required documents

  • Medical records
  • Complete blood count (if available)

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About the department

The Department of Pediatric and Adolescent Medicine at the University Hospital RWTH Aachen provides all modern methods of diagnostics and treatment of various diseases in children and adolescents. The department focuses on neonatology, pediatric neurology, pediatric hematology, oncology and stem cell transplantation. In addition, the outpatient clinic admits small patients with diseases of the endocrine organs, gastrointestinal tract, kidneys and urinary tract, as well as with urological problems, pulmonological, immunological, allergic and rheumatic pathologies. The department is headed by Prof. Dr. med. Norbert Wagner.

The highly qualified team of doctors takes care of the health of young patients. They make every effort in order to restore children's health. The department's outstanding medical service is awarded with the prestigious Ausgezeichnet. FÜR KINDER certification for children's medical facilities. Also, the department has wonderful children's infrastructure, including modern game rooms, patient rooms made in children's design. The department's doctors get along well with children and do everything possible to make the therapeutic process as comfortable as possible.

The service range of the department includes:

  • Neonatology
    • Treatment of newborns with severe diseases, such as heart defects, respiratory failure, asphyxiation, infections, seizures, metabolic disorders, etc.
  • Neuropediatrics
    • General neurological disorders in children
    • Convulsive disorders (epilepsy)
    • Neuromuscular diseases
    • Inflammatory diseases of the nervous system (for example, multiple sclerosis)
    • Cerebral vascular diseases
    • Hydrocephalus
    • Neurometabolic disorders
    • Brain malformations
    • Headaches
  • Pediatric hematology, oncology and bone marrow transplantation 
    • Treatment of children and adolescents with all benign and malignant blood diseases, tumors, blood-clotting disorders and vascular malformations
  • Pediatric endocrinology and diabetology
    • Treatment of children with hormonal disorders, type 1 and type 2 diabetes mellitus
  • Pediatric gastroenterology
    • Treatment of children with chronic abdominal pain, gastrointestinal developmental disorders, gastrointestinal motility disorders, chronic gastrointestinal diseases (inflammatory bowel disease, celiac disease, gastroesophageal reflux, etc.), liver diseases
  • Pediatric urology
    • Treatment of children with all diseases of the kidneys and urinary tract, particularly, hydronephrosis, vesicoureteral reflux, urethral valves, genital malformations (hypospadias, epispadias), undescended testes, phimosis, disorders of the urinary bladder emptying, urinary tract infections, genitourinary stones
  • Pediatric nephrology
    • Treatment of children with polycystic kidney disease, kidney dysfunction due to malformations (urethral valves, reflux), kidney inflammation (glomerulonephritis), hypertension, etc.
  • Pediatric pulmonology, allergology and immunology
    • Treatment of children with congenital and acquired diseases of the respiratory and immune systems, allergies, impaired immune regulation and immunodeficiencies
  • Pediatric rheumatology
    • Treatment of children with juvenile idiopathic arthritis, systemic lupus erythematosus and dermatomyositis
  • Other medical services

Photo of the doctor: (c) Uniklinik RWTH Aachen 


About hospital

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals!

As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the accurate diagnostics, effective therapy and productive research activities within one specialized center.

The hospital has more than 60 departments, institutes and interdisciplinary centers. A competent team of professionals, consisting of more than 7,000 employees (more than 940 doctors, including about 95 professors), takes care of the patients' health. In addition, multidisciplinary teams of nurses, physiotherapists, as well as medical and technical staff are available here. The patients and respectful attitude to their social, cultural and religious affiliations are at the center of all employees' efforts.

The cornerstone of the successful clinical practice is the innovative technical base. The hospital offers the most advanced diagnostic and therapeutic equipment. Thus, the hospital has all the resources in order to provide top-class medical services.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital RWTH Aachen live in comfortable single and double rooms. All patient rooms are designed with large windows, so one can enjoy a beautiful landscape view. Each patient room has an ensuite bathroom. The standard room furnishing includes an automatically adjustable bed, a bedside table, a spacious wardrobe, a TV, a radio and a telephone. Also, there is Wi-Fi access.

Meals and Menus

The patient and his accompanying person have a daily choice of three menus. If for any reason you do not eat all the foods, you will be offered an individual menu. Please inform the medical staff about your dietary preferences prior to the treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Religious services are available upon request.

Accompanying person

During the inpatient program, an accompanying person may stay with you in a patient room or at the hotel of your choice.

Hotel

During the outpatient program, you can live at a hotel of your choice. Managers will help you to choose the most suitable options.

The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET / CT, angiography, myelography, biopsy and other examinations. Treatment with medications, endoscopic and robotic operations, stereotaxic interventions is carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.

  • Embolization of tumors and vascular malformations
  • Aortic surgery, including in children
  • Radiosurgical interventions in the head and body region
  • Cochlear implantation
  • Treatment of all types of sports injuries

These are pathologies of the brain and spinal cord, benign and malignant tumors of various localizations, congenital and acquired heart defects, joint pathologies, stroke, neurodegenerative diseases, eye injuries, inflammatory skin diseases, allergies and other pathologies.

  • Oncology (EU Regional Center for Comprehensive Cancer Care Aachen)
  • Pediatric cardiac surgery
  • General and abdominal surgery
  • Plastic and burn surgery
  • Pediatric and adolescent medicine

Over 940 highly qualified doctors work at the hospital.