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University Hospital Frankfurt

Frankfurt am Main, Germany


Spinal muscular atrophy diagnosis (program ID: 302576)


Thomas Klingebiel

Head Physician
Prof. Dr. med.

Thomas Klingebiel

Department of Pediatric and Adolescent Medicine

Specialized in: pediatrics
Curriculum vitae keyboard_arrow_down

Professor Klingebiel ist Direktor der Klinik für Kinder- und Jugendmedizin der Johann Wolfgang Goethe Universität Frankfurt sowie der Prodekan des Fachbereichs Medizin. Er studierte Humanmedizin an den Universitäten Marburg und Lübeck, promovierte 1981 ebenfalls an der Universität Lübeck. Es folgten wissenschaftliche Assistenzzeiten am pathologischen Institut sowie der Kinderklinik der Universität Tübingen und im Jahre 2000 der Ruf auf eine Professur für Kinderheilkunde am Zentrum für Kinder- und Jugendmedizin der Universität Frankfurt am Main. Professor Klingebiel war Vorsitzender der Gesellschaft für Pädiatrische Onkologie und Hämatologie und ist Mitglied in verschiedenen Studienkommissionen sowie nationalen und internationalen Gesellschaften. Er wurde zudem mit dem Professor-Otto-Roth-Promotions-Preis, dem Van-Bekkum Award sowie dem Preis für Exzellente Lehre des Fachbereichs Medizin der Universität Frankfurt ausgezeichnet.

Publications keyboard_arrow_down

https://www.ncbi.nlm.nih.gov/pubmed/?term=Thomas+Klingebiel

About the department keyboard_arrow_down

The Department of Pediatric and Adolescent Medicine at the University Hospital Frankfurt specializes in 5 fields and deals with diagnosis and treatment of diseases in children and adolescents. The head of the Department is Prof. Dr. med. T. Klingebiel.

Focus on Neonatology: 

  • Treatment of premature and newborn babies

Focus on Neurology, Neurometabolics and Prevention:
Pediatric neurological clinical pictures also include:

  • Epileptology (cerebral seizures and their differential diagnoses)
  • Metabolic diseases that affect the nervous sytem
  • Neuromuscular diseases (myopathies, diseases of the peripheral nerves)
  • Congenital abnormal diseases of the nervous system (spina bifida, hydrocephalus, neurofibromatosis)
  • Neurology of the development (arrested development, cerebral palsy, speech development disorder, examination of premature babies)
  • Neurooncology (brain tumors)
  • Injuires of the nervous sytem (injuries of the skull base, spinal cord, peripheral nerves) 
  • Inflammatory diseases of the nervous system (meningitis, encephalitis, multiple sclerosis)
  • Neuropsychological deviations 

Focus on Allergology, Pneumology and Cystic Fibrosis:
Treatment of infestious, allergic diseases and respiratory tract diseases

  • Outpatient unit for cystic fibrosis
  • Outpatient unit for gastroenterology

Focus on Oncology, Hematology and Hemostasis:
Treatment of diseases of the hematopoietic system and malignant diseases in children and adolescents

  • Outpatient unit for hematology and oncology
  • Outpatient unit for blood-clotting disorders
  • Outpatient unit for angioedema
  • Outpatient unit for thalassemia

Focus on Stem Cell Transplantation and Immunology:
Treatment of benign and malignant diseases by stem cell transplantation and immunological diseases

  • Outpatient unit for immune deficiency

Focus on Pediatric Cardiology
The outpatient unit of pediatric cardiology provides treatment to about 4,000 patients every year. The range starts with congenital heard defects, cardiological examination and the further monitoring of medication, for example, within oncological diseases or antipsychotic therapy and ends up with the acquired heart defect. 

Moreover, the Department of Pediatric and Adolescent Medicine at the University Hospital Frankfurt also has an outpatient unit for pediatric cardiology. In cooperation with the University Hospital of Giessen (Prof. Scranz) the Pediatric Cardiology Center of Giessen offers an advanced experience in this field. The Department also includes interdisciplinary intensive care unit, which is supervised together witht the Department of Surgery, in particular, with the Department of Pediatric Surgery (Prof. Rolle). Since 2014 the Department has ist private MRI machine for the examination of children. This machine helps to examine head as well as other organs. The procedures of sedation and anesthesia can be carried out for little children right here. 

Range of services
The Department of Pediatric and Adolescent Medicine at the University Hospital Frankfurt under the direction of Prof. Dr. med. T. Klingebiel offers the entire spectrum of non-invasive and invasive pediatric cardiologic diagnosis:

  • ECG
  • Echocardiography
  • Transesophageal echocardiography
  • Continuous ECG
  • 24-hour monitoring of arterial pressure
  • Pacemaker monitoring
  • Load ECG (ergometry of bycicle and treadmill)
  • Orthostatic test

In close collaboration with Prof. Schranz, since the moment of the foundation of the Pediatric Cardiology Center of Giessen that consists of the Department of Pediatric and Adolescent Medicine at the University Hospital Frankfurt and the Pediatric Cardiology Center of Giessen/Marburg, there are used all interventional catheter methods of diagnosis and treatment for the acquired heart defects. Therefore, one of the most advanced cardiac catheterization stations oin Germany was put into operatiuon in November 2009. 

Program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • physical examination
  • neurological examination:
    • somatosensory evoked potentials
    • reflexes
    • muscle strength
    • muscle tone
    • senses of touch and sight
    • coordination
    • balance
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • enzyme tests
    • inflammation indicators
    • BSG
    • creatine kinase (CK)
    • immunoelectrophoresis
    • vitamin B12, vitamin D
    • thyroid parameters
    • parathormone
    • genetic testing for bi-allelic deletion
      of exon 7 of the SMN1 gene
  • electromyography (EMG)
  • brain and neck CT/ MRI
  • muscle biopsy if indicated
  • X-ray of the chest
  • CSF puncture with nervous water examination
  • cerebrovascular doppler ultrasound
  • nursing services
  • treatment via head doctor and all leading experts
  • explanation of individual treatment plan
Type of program :
Expected duration of the program:

The program includes:

  • Translation of medical documents up to 4 pages
  • Interpreter up to 3 hours
  • Translation of medical documents up to 8 pages
  • Interpreter up to 5 hours
  • Translation of medical documents up to 10 pages
  • Interpreter up to 8 hours
  • Insurance of unforeseen expenses in case of complications in course of treatment and within 48 months after treatment (сoverage amount is 200,000.00 €)
  • Free consultations with the attending physician for the period of 3 months after treatment completion
  • Translation of medical documents up to 10 pages
  • Interpreter up to 10 hours
  • Insurance of unforeseen expenses in case of complications in course of treatment and within 48 months after treatment (сoverage amount is 200,000.00 €)
  • Free consultations with the attending physician for the period of 3 months after treatment completion
  • Translation of medical documents up to 10 pages
  • Interpreter up to 15 hours
  • Transfer from the airport to the clinic and back to the airport
  • Insurance of unforeseen expenses in case of complications in course of treatment and within 48 months after treatment (сoverage amount is 200,000.00 €)
  • Free consultations with the attending physician for the period of 3 months after treatment completion
  • Translation of medical documents up to 10 pages
  • Interpreter up to 25 hours
  • Transfer from the airport to the clinic and back to the airport
  • Insurance of unforeseen expenses in case of complications in course of treatment and within 48 months after treatment (сoverage amount is 200,000.00 €)
  • Free consultations with the attending physician for the period of 3 months after treatment completion
info_outline Total costs:

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