University Hospital rechts der Isar der TU München

Munich, Germany


Radiation therapy of brain in Acute lymphoblastic leukemia (ALL) with brain damage (program ID: 126005)


Christian Peschel

Prof. Dr. med.

Christian Peschel

Department of Hematology and Oncology

Specialized in: hematology, internal medicine, oncology

Curriculum vitae keyboard_arrow_down

Wissenschaftliche Laufbahn und Forschungsgebiete
Prof. Peschel (*1950) forscht auf dem Gebiet der Hämatologie und Tumorbiologie. Durch das Verständnis der zellbiologischen und molekularen Grundlagen von Tumorerkrankungen soll die Grundlage für eine individualisierte, zielgerichtete Therapie bei Patienten mit Leukämien und Krebserkrankungen geschaffen werden. Als Krankheitsmodelle stehen akute und chronische Leukämien sowie Tumorerkrankungen des lymphatischen Systems (Non-Hodgkin Lymphome) im Fokus von grundlagenorientierter und translationaler Forschung. Prof. Peschel  studierte an der Universität Innsbruck Medizin, wo er 1989 habilitierte. Von 1985-1987 verbrachte er einen Forschungsaufenthalt in den USA bei William E. Paul, Laboratory of Immunology, am National Institutes of Health. 1990 - 1997 war er als leitender Oberarzt (C3 Professur) am Universitätsklinikum Mainz tätig. 1997 erfolgte der Ruf an die Fakultät für Medizin der TUM auf den neu gegründeten Lehrstuhl mit Schwerpunkt Hämatologie und internistische Onkologie.


Schlüsselpublikationen 
Renstrom J, Istvanffy R, Gauthier K, Shimono A, Mages J, Jardon-Alvarez A, Kroger M, Schiemann M, Busch DH, Esposito I, Lang R, Peschel C, Oostendorp RA: "Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells". Cell Stem Cell. 2009; 5: 157-167.
Bassermann F, von Klitzing C, Munch S, Bai RY, Kawaguchi H, Morris SW, Peschel C, Duyster J: "NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry". Cell. 2005; 122: 45-57.
Ringshausen I, Schneller F, Bogner C, Hipp S, Duyster J, Peschel C, Decker T: "Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with Proteinkinase C{delta}". Blood. 2002; 100: 3741-3748.
Bai RY, Ouyang T, Hahn S, Peschel C, Duysteraipford GB, Wagner H, Peschel C: "Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production and an immungenic phenotype in chronic lymphocytic leukemia B cells". Blood. 2000; 95: 999-1006.

About the department keyboard_arrow_down

The Department of Internal Medicine III at the university hospital Klinikum rechts der Isar focuses on the area of hematology and internistic oncology. Every year an experienced and dedicated team of doctors, under the direction of Univ. Prof. Dr. med. Christian Peschel, provides treatment to more than 7.000 patients from both Germany and abroad. All hematological tumor diseases, non-malignant disorders of hematopoiesis, coagulation disorders as well as patients with solid tumors are treated here.

The Department of Internal Medicine III at the university hospital Klinikum rechts der Isar is a part of interdisciplinary Centre for Tumor Therapy (TPZ), which also includes the Department of Radiotherapy as well as Surgery, Urology and Gynecology.

In addition to the state-of-the-art technical equipment and the applying of innovative and promising methods, an extensive consultation and personal commitment of the highly qualified team of doctors are the main factors of the self-conception of the Department of Internal Medicine III under the direction of Univ. Prof. Dr. med. Christian Peschel.

An experienced team of doctors of the Department of Internal Medicine III at the university hospital Klinikum rechts der Isar treats patients with blood and lymph node diseases as well as cancer patients with solid tumors.

Amongst others, the following diseases are treated here:

  • Acute and chronic leukemia (lung cancer)
  • Hodgkin’s lymphoma and non-Hodgkin’s lymphoma (lymph gland cancer)
  • Multiple myeloma (Plasmacytoma)
  • Small cell and non-small cell lung cancer
  • Chronic myeloproliferative disorders
  • Myelodysplastic syndromes (MDS)
  • Tumors of the gastrointestinal tract, bone and soft tissue, testis
  • Gastrointestinal Stromal Tumor (GIST)
  • Tumours of Soft Tissue and Bone (Sarcomas)
  • Gynecological oncology
  • Head and neck cancer
  • Testicular tumors
  • Melanoma (skin cancer)

Program includes:

  • Initial presentation in the clinic
  • case history collection
  • general clinical examination
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • differential blood count
    • inflammation indicators (CRP, ESR)
    • indicators blood coagulation
  • CT/MRI scanners of the complete organism
  • needle biopsy of the bone marrow
  • biopsy and histological examination of CSF
  • examination by experts of:
    • cardiology
    • otolaryngology
    • immunology
    • ophthalmology
  • radiation therapy of brain area
  • symptomatic treatment
  • control examinations
  • the cost of essential medicines and materials
  • nursing services
  • full hospital accommodation in 2 bedded room 
  • explanation of future recommendations

 

Total costs:
Type of program :
Duration of program:

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