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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC (639434) | Medicana International Istanbul Hospital - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.<\/p>\n\n<p style=\"text-align:justify\"><strong>After the completion of the operation<\/strong>, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.<\/p>\n\n<p style=\"text-align:justify\">Finally, the attending physician will evaluate the results of&nbsp;<strong>control examinations<\/strong>, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">MRI\/CT scan (not older than 3 months)<\/li>\n\t<li style=\"text-align: justify;\">Biopsy results (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>clinical history taking<\/li>\n\t<li>review of medical records<\/li>\n\t<li>physical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>general urine analysis<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>tumor markers&nbsp;<\/li>\n\t\t<li>inflammation indicators (CRP, ESR)<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>abdominal ultrasound scan<\/li>\n\t<li>CT scan\/MRI or PET-CT of abdomen<\/li>\n\t<li>preoperative care<\/li>\n\t<li>cytoreductive surgery to remove visible tumors<br \/>\n\tinside the abdomen and HIPEC<\/li>\n\t<li>histological and immunohistochemical<br \/>\n\texamination of removed tissues<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>cost of essential medicines<\/li>\n\t<li>nursing services<\/li>\n\t<li>stay in the hospital with a full board<\/li>\n\t<li>accommodation in a 2-bedroom ward<\/li>\n\t<li>elaboration of further recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align:justify\"><strong>During the first visit<\/strong>, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. 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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC

Medicana International Istanbul Hospital

Istanbul, Turkey
Program id # 639434
Doctor photo
Prof. Dr. med. Selman Laçin
In Vitro Fertilization Center
Specialized in: in vitro fertilization

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)

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About the department

The In Vitro Fertilization Center at the Medicana International Istanbul Hospital offers the comprehensive fertility treatment using modern and the most effective method, such as in vitro fertilization. The procedure involves the fertilization of the egg outside the female body. The doctors of the center are the true professionals in their field, which contributes to the high treatment success rates and the leading positions of the department at the national and international levels. The center is headed by Prof. Dr. med. Selman Laçin.

The essence of in vitro fertilization (IVF) is that the sperm cells are found with eggs in the test tube, and then they are placed in the uterus of the infertile woman. In a favorable outcome of the procedure (pregnancy), multiple pregnancy often develops and a woman gives birth to twins or triplets. The reason for this fact is that several eggs take part in the procedure of in vitro fertilization. At the request of a woman, doctors can make a reduction, namely the removal of excess embryos.

The in vitro fertilization (IVF) procedure is the best treatment method for the following pathological conditions:

  • Fallopian tube obstruction or its absence (after surgical removal)
  • Endometriosis and the inability to get pregnant after other treatment methods
  • Ovulation disorders, including after the unsuccessful treatment
  • Infertility without identified reasons
  • Low or abnormal sperm morphology
  • Other indications for IVF procedure

The in vitro fertilization procedure includes the following stages:

  • Follicle growth stimulation
  • Follicular puncture
  • Sperm preparation and egg fertilization
  • Embryo envelope incision
  • Embryo transfer
  • Pregnancy test

Each patient who undergoes IVF is assigned an individual treatment protocol. The dosages of drugs are selected according to her age, ovarian reserve, hormone levels, height-to-weight ratio, other important clinical details. The percentage of success during the IVF depends on many parameters and characteristics of the couple. For example, in women with a good ovarian reserve younger than 35 years, the probability of pregnancy after embryo transfer is 55-60%, whereas in women older than 40 years it is about 40%.

Also, to increase the chance of spermatozoa attachment to the egg cell, the doctors of the center perform an intrauterine insemination procedure. During this manipulation, the woman is prescribed medications or injections, which help to increase the number of mature eggs by two or three times. The spermatozoa are processed using the special methods, which allow to select motile spermatozoa. After the stimulation of egg release with the help of the hCG injection, the prepared sperm cells are injected into the uterus with the help of a special plastic tube, thus their path to the egg cell is shortened. Of course, the necessary condition for the implementation of such procedure is the patency of at least one fallopian tube. As a rule, if after 3 or 4 attempts the pregnancy does not occur, the doctors turn to other auxiliary reproductive technologies. 

The key condition for the in vitro fertilization procedure is the documentary confirmation of the official marriage registration, which the couple should provide at the center. Regardless of any circumstances, the treatment of married couples is not allowed if the man has no sperm or the woman does not develop eggs. The reproductive cells, which will be used in the treatment, are exclusively the cells of the spouses in a registered marriage.

Curriculum vitae

Education and Professional Experience

  • 1988 School of Medicine, GATA.
  • 1996 Postgraduate Education, School of Medicine, Dokuz Eylül University, Residency in Gynecology and Obstetrics.
  • 2002 Assistant Professor, Manisa Celal Bayar University, In Vitro Fertilization Center.
  • Department of Gynecology and Obstetrics, Karolinska Institute, Sweden.
  • In Vitro Fertilization Center, Tel-Aviv University, Israel.
  • 2004 - 2007 In Vitro Fertilization Center, Istanbul Memorial Hospital.
  • 2007 - 2008 In Vitro Fertilization Center, Istanbul Medical Park Bahçelievler Hospital.
  • Since 2008, Head of the In Vitro Fertilization Center, Medicana International Istanbul Hospital.

Photo of the doctor: (c) Medicana Health Group 


About hospital

The Medicana International Istanbul Hospital is a modern medical institution, which provides patients with an individual approach, excellent health service and attentive care. The hospital is part of the largest Turkish network of the Medicana hospitals. Due to its long successful clinical activities, this network has won the leading positions in the national and international medical arena. The hospital has the prestigious Joint Commission International certification.

The total area of ​​the medical facility is about 30,000 square meters, it consists of two modern buildings. The hospital has excellent infrastructure, accurate diagnostic systems, unique computerized medical devices. To provide surgical treatment, it has 8 state-of-the-art operating rooms, as well as special equipment for minimally invasive and robotic interventions.

The main focuses of the hospital specialization include liver transplantation, bone marrow transplantation, in vitro fertilization, hair transplantation and treatment of oncological diseases. The hospital annually diagnoses and treats thousands of patients both from Turkey and European countries. It employs the outstanding medical specialists with academic thinking, who use in their work innovative technologies and the very latest drugs, as well as pay due attention to the human attitude and respect for the patient.

Photo: (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Medicana International Istanbul Hospital live in comfortable modern rooms designed in light brown colors. The standard room includes an automatically adjustable bed, bedside table, wardrobe, shower, toilet and TV. The patient rooms have the Internet access. The hospital also provides the enhanced-comfort rooms.

Meals and Menus

The patients of the hospital are offered tasty and balanced three meals a day: buffet breakfast, lunch and dinner. Also, with appropriate clinical indications or if desired, a diet, individual menu may be provided.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV