DKD HELIOS Clinic Wiesbaden
Department of Hematology and Oncology (114081)
Klaus Maria Josten
Specialized in: hematology, oncology
About the department
The Department of Hematology and Oncology at the DKD HELIOS Clinic Wiesbaden offers the high-precision diagnostics and modern treatment of the full range of diseases of the hematopoietic system, as well as solid malignant tumors. The department mainly provides outpatient therapy. The medical team has in its arsenal all modern conservative treatment methods. The surgical resection of malignant tumors is performed by specialized surgeons. The interdisciplinary cooperation of doctors allows providing patients with the most comprehensive and effective treatment. The medical facility regularly holds tumor boards, during which the doctors individually consider each clinical case and develop a step-by-step treatment regimen. The therapeutic process is based on an individual approach to the patient, thanks to which the specialists achieve successful results. Great importance is attached to the emotional state of the patients, and therefore qualified psychologists are involved in the therapeutic process, if required. The doctors working in the department are guided by the current clinical protocols and recommendations of the German Cancer Society. The Chief Physician of the department is Dr. med. Klaus Maria Josten.
Chemotherapy is an integral component of the treatment of malignant diseases, as well as one of the most effective methods of fighting cancer. The department's specialists have many years of experience in the field of chemotherapy, thanks to which they successfully select the optimal complex of drugs for each patient, which will most effectively destroy cancer cells. The duration and type of chemotherapy treatment depends on the diagnosis, stage of cancer, the severity of the patient's general condition, his age and other factors. The doctors of the department carry out chemotherapy on an outpatient basis, so patients do not need to be constantly in the hospital. At the same time, the attending physician carefully monitors the patient's condition and the side effects of treatment. In most cases, the department's oncologists conduct intravenous chemotherapy using special catheters and port systems. In addition, each patient is assigned an individual chemotherapy regimen – the course of chemotherapy can be continuous or it can include treatment cycles and breaks between them to restore the body. In rare cases, chemotherapy can be used as monotherapy, but it is usually combined with other conservative and surgical treatments.
The department actively uses immunotherapy. The mechanism of action of immunotherapy is the activation of the immune system in order to protect the body from cancer cells. On the surface of T lymphocytes (cells of the immune system) there are special proteins codenamed PD-1 and CTLA-4. They are called immune response checkpoints. The tumor cells neutralize T cells, as a result of which the immune system ceases to fight the oncological process in the human body. The introduction of immunotherapy drugs into the patient's body activates T lymphocytes. In addition, it is possible to "train" the patient's own T lymphocytes to recognize tumor cells in the laboratory. To do this, T lymphocytes are isolated from the patient's blood, and after "training" they are returned back to the body so that they recognize and destroy tumor cells. Today, the department's doctors successfully use immunotherapy to treat melanoma, lung, kidney, stomach, bladder, prostate, pancreatic cancers, as well as Hodgkin's lymphoma and other oncological diseases. The patient receives drugs intravenously. The total duration of the course of treatment is determined by an oncologist.
The department's team of oncologists widely uses antibody therapy. Antibodies are special molecules that are synthesized by the cells of the immune system in response to the body's contact with a foreign agent. The essence of the treatment is the injection of antibodies into the patient's body, which activate his own immune system to fight cancer cells. Antibody drugs compare favorably with chemicals in their selectivity of action, which ensures high efficiency of therapy and minimal side effects. The use of antibodies is usually combined with other treatments, such as radiation therapy or chemotherapy. The technique is effective for the treatment of both blood cancer and malignant solid tumors.
The department's therapeutic offer is complemented by hormonal therapy. The method is highly effective in the treatment of prostate cancer, breast cancer and gynecological oncological diseases. The development of these types of cancer may be due to the action of hormones, and therefore their treatment involves the use of special drugs that block or modify the effect of hormones on tumor cells. In some cases, hormonal therapy can be applied as a monotherapy, but it also works well with other therapies.
The department specializes in the diagnostics and treatment of the following diseases:
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Chronic lymphoblastic leukemia
- Chronic myeloid leukemia
- Myelodysplastic syndrome
- Myeloproliferative disorders
- Malignant tumors of the gastrointestinal tract (stomach, colon, esophageal cancers, etc.)
- Malignant tumors in the head and neck
- Malignant tumors of the lungs and other thoracic organs
- Malignant tumors of the breast
- Malignant tumors of the female genital organs
- Malignant tumors of the prostate
- Malignant tumors of the bladder
- Malignant tumors of the kidneys
- Malignant tumors of the liver
- Malignant tumors of the skin
- Malignant tumors of bones and soft tissues (sarcomas)
- Other hematological and oncological diseases
The department's main therapeutic options include:
- Antibody therapy
- Hormonal therapy
- Transfusion of blood products
- Participation in clinical trials (at the patient's request)
- Other treatment methods
Photo of the doctor: (c) DKD Helios Klinik Wiesbaden
Department of Hematology and Oncology.
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