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In vitro fertilization (IVF) long protocol (617371) | Medipol Mega University Hospital Istanbul - BookingHealth
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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. We provide an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, preparing medical reports.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Results of hormone blood tests (if available)<\/li>\n\t<li style=\"text-align: justify;\">Pelvic ultrasoud (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li style=\"text-align:justify\">Initial presentation in the clinic<\/li>\n\t<li style=\"text-align:justify\">Case history taking<\/li>\n\t<li style=\"text-align:justify\">Review of medical records<\/li>\n\t<li style=\"text-align:justify\">General physical examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Laboratory tests:&nbsp;<\/strong>\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Complete blood count&nbsp;<\/li>\n\t\t<li>General urine test<\/li>\n\t\t<li>Biochemical blood test<\/li>\n\t\t<li>Inflammation markers<\/li>\n\t\t<li>Blood coagulation test&nbsp;<\/li>\n\t\t<li>Immune status<\/li>\n\t\t<li>Analysis for infections<\/li>\n\t\t<li>Hormone levels:\n\t\t<ul>\n\t\t\t<li>FSH<\/li>\n\t\t\t<li>LH<\/li>\n\t\t\t<li>Androgens<\/li>\n\t\t\t<li>Progesterone<\/li>\n\t\t\t<li>Prolactin<\/li>\n\t\t\t<li>TSH-basal, fT3, fT4&nbsp;<\/li>\n\t\t<\/ul>\n\t\t<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Ultrasound examination of abdomen and small pelvic organs&nbsp;<\/li>\n\t<li style=\"text-align:justify\">Transvaginal ultrasound examination<\/li>\n\t<li style=\"text-align:justify\">Gynecological examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Examination of the men<\/strong>:\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Spermogram<\/li>\n\t\t<li>Urethral smear analysis<\/li>\n\t\t<li>Tests for infections<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Hormonal stimulation&nbsp;<\/li>\n\t<li style=\"text-align:justify\"><strong>In vitro fertilization (IVF)<\/strong><\/li>\n\t<li style=\"text-align:justify\">Nursing services<\/li>\n\t<li style=\"text-align:justify\">Consultation of related specialists<\/li>\n\t<li style=\"text-align:justify\">Treatment by head doctor and all leading experts<\/li>\n\t<li style=\"text-align:justify\">Explanation of the individual treatment plan<\/li>\n<\/ul>\n\n<p style=\"text-align:justify\"><em>All aspects of the program can be discussed with a medical advisor.<\/em><\/p>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\">You <strong>arrive in the hospital<\/strong> on the 19th day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. 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In vitro fertilization (IVF) long protocol in Medipol Mega University Hospital Istanbul

Medipol Mega University Hospital Istanbul

Istanbul, Turkey
Program id # 617371
Doctor photo
Assist. Prof. Dr. med. Ayşe Karahasanoglu
Department of Reproductive Medicine
Specialized in: reproductive medicine

The program includes:

  • Initial presentation in the clinic
  • Case history taking
  • Review of medical records
  • General physical examination
  • Laboratory tests: 
    • Complete blood count 
    • General urine test
    • Biochemical blood test
    • Inflammation markers
    • Blood coagulation test 
    • Immune status
    • Analysis for infections
    • Hormone levels:
      • FSH
      • LH
      • Androgens
      • Progesterone
      • Prolactin
      • TSH-basal, fT3, fT4 
  • Ultrasound examination of abdomen and small pelvic organs 
  • Transvaginal ultrasound examination
  • Gynecological examination
  • Examination of the men:
    • Spermogram
    • Urethral smear analysis
    • Tests for infections
  • Hormonal stimulation 
  • In vitro fertilization (IVF)
  • Nursing services
  • Consultation of related specialists
  • Treatment by head doctor and all leading experts
  • Explanation of the individual treatment plan

All aspects of the program can be discussed with a medical advisor.

How program is carried out

You arrive in the hospital on the 19th day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.

The reproductologist will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.

For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).

Stages of treatment

Blockage. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.

Ovarian stimulation. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.

The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).

Egg collection. In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men – the ICSI procedure).

Fertilization. 2-6 hours after egg collection, eggs are fertilized with the husband’s sperm. This is a laboratory procedure and no patient involvement is required.

Embryo culture. Fertilized eggs will be cultured for 1-5 days. According to patients’ needs and embryo status, best 1-3 embryos can be transferred to the womb.

Preimplantation genetic diagnosis. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.

Embryo transfer. This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.

Pregnancy test. This test can be done 14 days after the embryo transfer.

Service support

We fully support your trip, regardless of the chosen program. We provide an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, preparing medical reports.

Required documents

  • Medical records
  • Results of hormone blood tests (if available)
  • Pelvic ultrasoud (if available)

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About the department

The Department of Reproductive Medicine at the Medipol Mega University Hospital offers the full range of diagnostic and therapeutic interventions for fertility treatment in men and women. The department's specialists have long successful experience, and therefore they effectively detect and eliminate the causes of infertility, and also provide high-quality medical care to couples with infertility of unknown origin. Particular focus is on in vitro fertilization (IVF), which today gives the highest chances of conceiving a child to couples who cannot achieve pregnancy naturally. The department is headed by Assist. Prof. Dr. med. Ayşe Karahasanoglu.

The treatment begins with a consultation with the attending physician, who studies the medical history of the couple, clarifies the duration of unprotected sexual life, and then prescribes the necessary diagnostic examinations to detect the causes of infertility. Infertility can be caused by health problems in both women and men. There are also cases of combined infertility, when both of the spouses have problems, which prevent them from conceiving a child. With the results of diagnostics, the specialist in reproductive medicine develops the optimal treatment regimen, which will ensure the couple with a long-awaited pregnancy.

One of the most effective treatment methods for infertility is IVF. This method is effective even in the case of fallopian tube obstruction, severe male factor infertility (oligoasthenoteratozoospermia, cryptozoospermia, azoospermia), diminished ovarian reserve, genetic pathology in parents.

In vitro fertilization consists of several stages. If the indication for IVF is only the female factor of infertility, there is no need for ICSI, TESA, MESA techniques, transplantation of the patient's own cryopreserved eggs or donor eggs, then IVF consists of the following stages:

  • Preparation of the woman's body for hormonal stimulation and ovarian stimulation 
  • Follicular puncture
  • Fertilization of eggs obtained as a result of puncture
  • Embryo culture
  • Embryo transfer
  • Pregnancy test

The department's ​​competence also includes the preimplantation genetic diagnosis to exclude genetic diseases in the embryo before it is transferred to the uterine cavity. Thus, future parents can be sure that the child does not have any genetic syndromes.

If the diagnostic tests reveal pathological changes in the spermogram, the fertility specialist may recommend IVF types, which are more complex and effective for the male infertility factor. These include intracytoplasmic sperm injection (ICSI) – the technique, which helps inject the sperm cell directly into the egg cytoplasm, bypassing all its membranes. The TESA and MESA methods are used when the spermogram shows a complete absence of sperm, which can fertilize an egg. The sperm is extracted from the eggs or appendages, processed in the laboratory and injected into the egg.

Since the treatment of infertility can be a cause of stress, the couples receive professional psychological support and can also share experiences in support groups.

The department is one of the best in Turkey in the field of its ​​expertise, and also regularly admits patients from foreign countries for treatment. Thanks to the advanced medical and technical base, the professionalism of doctors and an individual approach, it achieves high success rates of the IVF procedure – the couples obtain the happiness of being parents of healthy babies.

The department's range of medical services includes: 

  • Diagnostics and treatment of uterine diseases, which prevent the conception of pregnancy
  • Endoscopic procedures for the diagnostics and treatment of fallopian tube obstruction and pathological changes in the ovaries
  • Diagnostics and monitoring of couples with recurrent miscarriage
  • Ovarian stimulation
  • Intrauterine insemination
  • In vitro fertilization (IVF)
  • Intracytoplasmic sperm injection (ICSI)
  • Testicular sperm aspiration (TESA)
  • Percutaneous epididymal sperm aspiration (PESA)
  • Auxiliary hatching
  • Embryo cryopreservation
  • Testicular tissue cryopreservation
  • Preimplantation genetic diagnosis
  • Other diagnostic and therapeutic options

Curriculum vitae

Higher Education

  • 2010 Internship in Gynecology, Süleymaniye Kadın Doğum Hospital, Istanbul, Turkey.
  • 1999 Study of Human Medicine at the Faculty of Medicine of the Istanbul University.

Professional Career

  • 2014 - 2016 Work at the Memorial Şişli Hospital, Istanbul, Turkey.
  • 2004 - 2014 Work at the Süleymaniye Kadın Doğum Hospital, Istanbul, Turkey.
  • Work in the Department of Reproductive Medicine at the Medipol Mega University Hospital.

Photo of the doctor: (c) Medipol Mega University Hospital Istanbul


About hospital

Accommodation in hospital

Hospital accommodation

The patients and their families can stay at the Medipol Guest House, which is a 1-minute walk from the Medipol Mega University Hospital Istanbul.