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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC (639422) | Medipol Mega University Hospital Istanbul - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.<\/p>\n\n<p style=\"text-align:justify\"><strong>After the completion of the operation<\/strong>, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. 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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC

Medipol Mega University Hospital Istanbul

Istanbul, Turkey
Program id # 639422
Doctor photo
Prof. Dr. med. Huriye Ayşe Parlakgümüş
Department of Gynecology and Obstetrics
Specialized in: gynecology, obstetrics

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)

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About the department

The Department of Gynecology and Obstetrics at the Medipol Mega University Hospital Istanbul offers the high-precision diagnostics and treatment of the full range of diseases of the female reproductive organs. The department also offers integrated management of pregnancy in accordance with the current protocols of professional societies, safe childbirth and postnatal care for mother and baby. The department's medical team has excellent infrastructure, including modern diagnostic rooms, operating rooms with all the necessary equipment and monitoring systems. The Chief Physician of the department is Prof. Dr. med. Huriye Ayşe Parlakgümüş.

The department's specialists pay due attention to the timely and accurate diagnostics, which is the key to a successful treatment result. The department uses diagnostic instrumental methods, including the cytological smear, ultrasound examination and colposcopy. The laparoscopic techniques and hysteroscopy are also applied for the diagnostics and treatment of gynecological diseases and infertility.

The department's experts in gynecologic oncology have exceptional competencies in the treatment of ovarian cancer. If necessary, they perform partial or total removal of the uterus, ovaries, fallopian tubes, nearby lymph nodes, peritoneum and omentum, as well as surgeries to remove distant metastases. In the case of detection of ovarian cancer at the initial stage, the uterus and the second ovary are not removed, which allows the patient to maintain reproductive function. The success rate of surgical treatment of ovarian cancer in the department reaches 93%, while in many medical centers in Europe this rate does not exceed 50%.

In addition to the diagnostics and treatment of all gynecological diseases, the department offers a wide range of services in obstetrics, including pain management during childbirth, water birth, physiological and high-risk pregnancies, prenatal and postnatal monitoring. Particular attention is paid to water birth, since this method does not require medical care or measures for labor induction.

The key focuses of the department's work include:

  • Diagnostics and treatment of general gynecological pathologies
  • Diagnostics and treatment of cancers of the female reproductive system (focus on ovarian cancer, uterine and cervical cancer)
  • Diagnostics and treatment of infertility
  • Diagnostics and treatment of urogynecological pathologies (urinary incontinence, pelvic organ prolapse)
  • Integrated management of pregnancy, including high-risk pregnancy
  • Childbirth (also, water birth)
  • Pain management during childbirth
  • Postnatal care for mother and baby
  • Other medical services

Curriculum vitae

Education

  • 2019 University of Barcelona, International Master's Degree Program in Obstetrics.
  • 2009 Royal College (Perinatology, Gynecology and Obstetrics).
  • 2004 Obstetrics and Gynecology, Hacettepe University.
  • 2000 Faculty of Medicine at the Hacettepe University.

Professional Career

  • 2015 - 2019 Work in the Private Medline Adana Hospital.
  • 2005 Department of Gynecology, Obstetrics and Perinatal Medicine at the University Hospital Bonn.
  • 2005 - 2015 Faculty of Medicine, Department of Gynecology and Obstetrics, Başkent University.

Photo of the doctor: (c) Medipol Mega University Hospital Istanbul 


About hospital

Accommodation in hospital

Hospital accommodation

The patients and their families can stay at the Medipol Guest House, which is a 1-minute walk from the Medipol Mega University Hospital Istanbul.