Treatment of colon cancer with embolization or chemoembolization (program ID: 689364)
University Hospital Marburg UKGM
Siegfried BienSpecialized in: diagnostic and interventional neuroradiology
Department of Diagnostic and Interventional Neuroradiology
- Initial presentation in the hospital
- Clinical history taking
- Review of available medical records
- Physical examination
- Laboratory tests:
- Complete blood count
- General urine analysis
- Biochemical analysis of blood
- Tumor markers
- Inflammation indicators (CRP, ESR)
- Ultrasound scan
- CT scan / MRI
- Preoperative care
- Embolization or chemoembolization, 2 procedures
- Symptomatic treatment
- Cost of essential medicines
- Nursing services
- Elaboration of further recommendations
How program is carried out
During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI. This will allow the doctor to determine which vessels are feeding the tumor and its metastases, as well as determine how well you will tolerate the procedure.
Chemoembolization begins with local anesthesia and catheterization of the femoral artery. The thin catheter is inserted through a few centimeters long incision of the blood vessel. The doctor gradually moves the catheter to the vessel feeding the primary tumor or its metastases. The procedure is carried out under visual control, an angiographic device is used for this. The vascular bed and the position of the catheter in it are displayed on the screen of the angiograph.
When the catheter reaches a suspected artery, a contrast agent is injected through it. Due to the introduction of the contrast agent, the doctor clearly sees the smallest vessels of the tumor and the surrounding healthy tissues on the screen of the angiograph. After that, he injects emboli into the tumor vessels through the same catheter.
Emboli are the spirals or the liquid microspheres. The type of embolus is selected individually, taking into account the diameter of the target vessel. When carrying out chemoembolization, a solution of a chemotherapy drug is additionally injected into the tumor vessel. Due to the subsequent closure of the vessel lumen with an embolus, the chemotherapy drug influences the tumor for a long time. In addition, the drug does not enter the systemic circulation, which allows doctors to use high doses of chemotherapeutic agents without the development of serious side effects. Chemoembolization leads to the destruction of the tumor or slowing down its progression.
After that, the catheter is removed from the artery. The doctor puts a vascular suture on the femoral artery and closes it with a sterile dressing. During chemoembolization, you will be awake. General anesthesia is not used, which significantly reduces the risks of the procedure and allows performing it on an outpatient basis, avoiding long hospital stay.
After the first procedure, you will stay under the supervision of an interventional oncologist and general practitioner. If necessary, you will receive symptomatic treatment. As a rule, a second chemoembolization procedure is performed in 3-5 days after the first one in order to consolidate the therapeutic effect. After that, you will receive recommendations for further follow-up and treatment.
- Medical records
- Esophagogastroduodenoscopy (EGD), MRI/CT scan (not older than 3 months)
- Biopsy results (if available)
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About the department
The Department of Diagnostic and Interventional Neuroradiology at the University Hospital Marburg UKGM offers the full range of imaging diagnostics and interventional treatment of diseases of the nervous system under imaging guidance. The department is headed by Prof. Dr. med. Siegfried Bien.
The experienced specialists with unique competencies work with patients, which allows them to provide first-class medical care to patients with pathologies of varying severity. The doctors from the Departments of Neurology and Neurosurgery are often involved in the diagnostic and therapeutic process. The state-of-the-art technical base of the department also contributes to successful clinical practice.
The department’s spectrum of medical services includes:
- Diagnostic neuroradiology
- Computed tomography (CT) scan of the head, neck and spine
- Magnetic resonance imaging (MRI) of the head, neck and spine
- Angiography of the vessels of the head and neck, as well as vessels of the spinal cord, including CT/MRI angiography
- Myelography with registration of functional indicators
- X-ray studies
- Interventional neuroradiology
- Thrombectomy (for stroke treatment)
- Stent angioplasty for stenosis of cerebral or other intracranial arteries
- Treatment of intracranial aneurysms
- Treatment of vascularized tumors, arteriovenous malformations and dural arteriovenous fistulas
- Treatment of extracranial vascular malformations
- CT-guided pain therapy for back pain (periradicular therapy, facet joint block, etc.)
- Other diagnostic and therapeutic options
Photo of the doctor: (c) UKGM - Universitätsklinikum Gießen und Marburg GmbH