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In vitro fertilization (IVF) long protocol (280354) | University Hospital Bonn - BookingHealth
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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. We provide an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, preparing medical reports.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Results of hormone blood tests (if available)<\/li>\n\t<li style=\"text-align: justify;\">Pelvic ultrasoud (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li style=\"text-align:justify\">Initial presentation in the clinic<\/li>\n\t<li style=\"text-align:justify\">Case history taking<\/li>\n\t<li style=\"text-align:justify\">Review of medical records<\/li>\n\t<li style=\"text-align:justify\">General physical examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Laboratory tests:&nbsp;<\/strong>\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Complete blood count&nbsp;<\/li>\n\t\t<li>General urine test<\/li>\n\t\t<li>Biochemical blood test<\/li>\n\t\t<li>Inflammation markers<\/li>\n\t\t<li>Blood coagulation test&nbsp;<\/li>\n\t\t<li>Immune status<\/li>\n\t\t<li>Analysis for infections<\/li>\n\t\t<li>Hormone levels:\n\t\t<ul>\n\t\t\t<li>FSH<\/li>\n\t\t\t<li>LH<\/li>\n\t\t\t<li>Androgens<\/li>\n\t\t\t<li>Progesterone<\/li>\n\t\t\t<li>Prolactin<\/li>\n\t\t\t<li>TSH-basal, fT3, fT4&nbsp;<\/li>\n\t\t<\/ul>\n\t\t<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Ultrasound examination of abdomen and small pelvic organs&nbsp;<\/li>\n\t<li style=\"text-align:justify\">Transvaginal ultrasound examination<\/li>\n\t<li style=\"text-align:justify\">Gynecological examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Examination of the men<\/strong>:\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Spermogram<\/li>\n\t\t<li>Urethral smear analysis<\/li>\n\t\t<li>Tests for infections<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Hormonal stimulation&nbsp;<\/li>\n\t<li style=\"text-align:justify\"><strong>In vitro fertilization (IVF)<\/strong><\/li>\n\t<li style=\"text-align:justify\">Nursing services<\/li>\n\t<li style=\"text-align:justify\">Consultation of related specialists<\/li>\n\t<li style=\"text-align:justify\">Treatment by head doctor and all leading experts<\/li>\n\t<li style=\"text-align:justify\">Explanation of the individual treatment plan<\/li>\n<\/ul>\n\n<p style=\"text-align:justify\"><em>All aspects of the program can be discussed with a medical advisor.<\/em><\/p>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\">You <strong>arrive in the hospital<\/strong> on the 19th day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. 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In vitro fertilization (IVF) long protocol

University Hospital Bonn

Bonn, Germany
Program id # 280354
Doctor photo
Prof. Dr. med. Nicole Sänger
Department of Gynecological Endocrinology and Reproductive Medicine
Specialized in: gynecological endocrinology, reproductive medicine

The program includes:

  • Initial presentation in the clinic
  • Case history taking
  • Review of medical records
  • General physical examination
  • Laboratory tests: 
    • Complete blood count 
    • General urine test
    • Biochemical blood test
    • Inflammation markers
    • Blood coagulation test 
    • Immune status
    • Analysis for infections
    • Hormone levels:
      • FSH
      • LH
      • Androgens
      • Progesterone
      • Prolactin
      • TSH-basal, fT3, fT4 
  • Ultrasound examination of abdomen and small pelvic organs 
  • Transvaginal ultrasound examination
  • Gynecological examination
  • Examination of the men:
    • Spermogram
    • Urethral smear analysis
    • Tests for infections
  • Hormonal stimulation 
  • In vitro fertilization (IVF)
  • Nursing services
  • Consultation of related specialists
  • Treatment by head doctor and all leading experts
  • Explanation of the individual treatment plan

All aspects of the program can be discussed with a medical advisor.

How program is carried out

You arrive in the hospital on the 19th day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.

The reproductologist will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.

For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).

Stages of treatment

Blockage. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.

Ovarian stimulation. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.

The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).

Egg collection. In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men – the ICSI procedure).

Fertilization. 2-6 hours after egg collection, eggs are fertilized with the husband’s sperm. This is a laboratory procedure and no patient involvement is required.

Embryo culture. Fertilized eggs will be cultured for 1-5 days. According to patients’ needs and embryo status, best 1-3 embryos can be transferred to the womb.

Preimplantation genetic diagnosis. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.

Embryo transfer. This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.

Pregnancy test. This test can be done 14 days after the embryo transfer.

Service support

We fully support your trip, regardless of the chosen program. We provide an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, preparing medical reports.

Required documents

  • Medical records
  • Results of hormone blood tests (if available)
  • Pelvic ultrasoud (if available)

Service

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About the department

The Department of Gynecological Endocrinology and Reproductive Medicine at the University Hospital Bonn offers the full range of diagnostic and treatment services in its areas of specialization. In addition to all standard treatment methods of infertility, the department uses additional diagnostic and treatment methods, for example, polar body biopsy (within the preimplantation diagnostics of genetic diseases), auxiliary hatching, the use of calcium ionophores for egg activation, intracytoplasmic morphologically selected sperm injection (IMSI), etc. The department is one of the leading Centers for Reproductive Medicine in Germany. The Chief Physician of the department is Prof. Dr. med. Nicole Sänger.

The department's specialists have independently developed some of the assisted reproductive technologies (ART) and continue to work intensively on their further improvement. The laboratory in the department is among the best in Germany in the field ART. It also offers various methods of cryopreservation of sperm, eggs, cryopreservation of testicular and ovarian tissues, etc. Thus, the department provides the highest quality standards of reproductive medicine services and has an impeccable international reputation.

In the field of gynecological endocrinology, the main focus is on hormonal disorders and related diseases. These include, for example, hair loss, acne, hirsutism, irregular menstruation, etc. Each patient undergoes a comprehensive diagnostics, on the basis of which an individual hormone therapy program is prescribed, if it is indicated.

The department’s diagnostic and therapeutic range of services:

  • Diagnostics and treatment of inflammatory diseases of the pelvic organs in women
  • Diagnostics and treatment of non-inflammatory diseases of the female reproductive organs (for example, endometriosis)
  • Endoscopic surgery
  • Gynecological endocrinology
  • Reproductive medicine
    • IVF
    • Intracytoplasmic sperm injection (ICSI)
    • Open testicular biopsy (TESE)
    • Intrauterine insemination (IUI)
    • Determination of the optimal time for conception
    • Polar body biopsy (within the preimplantation genetic diagnostics)
    • Supportive hatching
    • Use of calcium ionophores for egg activation
    • Intracytoplasmic morphologically selected sperm injection (IMSI)
    • Sequential drugs (antiandrogen therapy in women)
    • EmbryoScope produces
  • Procedures for preserving the reproductive function in oncological diseases
    • Ovarian tissue biopsy with cryopreservation
    • Protection of the ovaries from chemical and radiation injury
    • Ovarian tissue replantation
  • And other diagnostic and therapeutic methods

Curriculum vitae

Membership in Professional Societies

  • German Society of Gynecology and Obstetrics.
  • German Society of Gynecological Endocrinology and Reproductive Medicine.
  • German Menopause Society.
  • Middle Rhine Society for Gynecology and Obstetrics.
  • German Society for Reproductive Medicine.
  • Federal Association of German Reproductive Medical Centres.
  • European Society of Human Reproduction and Embryology (ESHRE).
  • International Society of Fertility Preservation (ISFP).
  • Professional Society FertiPROTEKT.

Board Memberships

  • German Society of Gynecology and Obstetrics.
  • German Society of Gynecological Endocrinology and Reproductive Medicine.
  • Professional Society FertiPROTEKT.

Photo of the doctor: (c) Universitätsklinikum Bonn  


About hospital

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany!

The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combines all the highest standards of modern university medicine of the international level. A highly competent team of experienced physicians, which consists of more than 8,000 employees from various fields, takes care of the patients’ health.

The hospital has 32 specialized departments and 23 institutes, which implement the highest standards of treatment in Germany. On their basis, in addition to  the successful clinical activities, the productive research and training of young specialists are carried out. Also, the hospital has 10 intensive care units and more than 30 cutting-edge operating rooms. They are equipped with the advanced surgical, navigation and monitoring systems, which provide sparing and the most effective surgical treatment. The total number of places for hospitalization is 1,250 beds.

The hospital presents all fields of medicine, while many of them are awarded by prestigious German and international certificates. For example, in 2007, the Comprehensive Cancer Center of the hospital became one of the four winners at the nationwide competition among Cancer Centers of Excellence. The research focuses primarily on the clinical genetics and genetic epidemiology, neurology, immunology and infectiology, hepatology and gastroenterology, and diseases of the cardiovascular system. The research findings contribute to the development of new therapeutic methods and overall improvement of treatment in Germany. 

The main value for all employees of the hospital in Germany is human health, his individual needs and wishes, therefore, despite the high-tech infrastructure, the focus remains on the human attitude and respect for each patient.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital Bonn live in cozy single, double and triple rooms, designed in bright colors. The standard room furnishing includes a comfortable bed with a remote control, a bedside table, a wardrobe, a table and chairs, as well as a TV and a telephone. Each patient room is equipped with an ensuite bathroom with toilet and shower. The hospital also provides enhanced-comfort rooms.

Meals and Menus

The patients of the hospital are offered tasty and balanced three meals a day: breakfast, lunch and dinner. Every day each meal features three different menus, including a vegetarian one. If you for some reason do not eat all the food, you will be offered an individual menu. Please inform the medical staff about your dietary preferences prior to the treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Christian priests are available for the patients at any time. Representatives of other religions may be requested at any time.

Accompanying person

Your companion may stay with you in your room or at a hotel of your choice during the fixed program.

Hotel

You may stay at the hotel during the outpatient program. Our employees will support you for selecting the best option.

The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET / CT, angiography, myelography, biopsy and other examinations. Treatment with medications, endoscopic and robotic operations, stereotaxic interventions is carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.

  • Surgical treatment of the brain tumors, tumors of spinal cord and spine
  • Replacement of all joints, resection arthroplasty
  • Deep brain stimulation and vagus nerve stimulation in patients with epilepsy
  • Multimodal complex treatment of Parkinson disease
  • Thoracic endovascular aortic repair (TEVAR)

These are benign and malignant breast pathologies, malignant tumors of various localizations, neuromuscular diseases, stroke, retinal pathologies and various visual impairments, infertility, autoimmune diseases, epilepsy, coronary artery disease and myocardial infarction, leukemia and other pathologies.

  • Ophthalmology
  • Epileptology
  • Reproductive medicine
  • Hematology and oncology
  • Neurosurgery

Over 8,000 highly qualified doctors and other employees work at the hospital.