Department of Pediatric Gastroenterology, Hepatology, and Metabolic Disorders - Charite University Hospital Berlin
Charite University Hospital Berlin
Berlin, Germany
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Department id #
26124
Prof. Dr. med. Philip Bufler
Department of Pediatric Gastroenterology, Hepatology, and Metabolic Disorders
Specialized in: pediatric gastroenterology, metabolic disorders About the Department of Pediatric Gastroenterology, Hepatology, and Metabolic Disorders at Charite University Hospital Berlin
The Department of Pediatric Gastroenterology, Hepatology and Metabolic Disorders at the Charite University Hospital Berlin provides a full range of medical services within its fields of expertise. The department's team of physicians treats young patients with diseases of the gastrointestinal tract, liver, and metabolic disorders, with a special emphasis on managing chronic and rare conditions of the digestive system. Clinical practice includes pediatric consultations, laboratory and ultrasound diagnostics, endoscopic examinations, and conservative treatment. The department is integrated into the liver transplantation program at Charite University Hospital Berlin, enabling specialists to prepare children for liver transplantation surgery and provide comprehensive post-operative care. The medical team works closely with pediatric surgeons, oncologists, cardiologists, rheumatologists, immunologists, and other experts to provide interdisciplinary care for each child. Treatment is delivered on both an inpatient and outpatient basis. The department's physicians utilize many modern evidence-based methodologies that are designed to fully restore the health of young patients. The department is headed by Prof. Dr. med. Philip Bufler.
The department's physicians specialize in treating young patients with chronic inflammatory bowel diseases (IBD) – Crohn's disease and ulcerative colitis. In many cases, these conditions develop due to a rare immunodeficiency disorder, which pediatric gastroenterologists identify through comprehensive immunological diagnostics. The treatment plan for a child with IBD is developed on an individualized basis. It typically includes the administration of various medication classes: anti-inflammatory drugs, immunomodulators, enzyme preparations, probiotics, and antibiotics. Nutritional therapy is also an integral component of treatment. In complex clinical cases, endoscopic intervention or open surgery may be required.
In the field of gastroenterology, the clinic's physicians have accumulated extensive experience in treating children with short bowel syndrome, celiac disease, disorders of gastric, esophageal and intestinal motility, gastroesophageal reflux disease, food intolerances, and congenital malformations of the gastrointestinal tract. Treatment is conducted in close cooperation with the clinic's pediatric surgeons.
The area of pediatric hepatology deserves special attention. Specialists in this field provide comprehensive treatment for diseases of the liver, gallbladder, and biliary tract. The medical team focuses on young patients with hepatitis B and C, autoimmune hepatitis, congenital malformations of the bile ducts, Wilson's disease, and other conditions. For each child, an optimal medication regimen is developed, taking into account the specific diagnosis, age, and general condition. The department also provides professional care for young patients before and after liver transplantation – the clinic is a partner in the Charite Clinic's liver transplantation program, which has earned a high reputation in the European healthcare system for its outstanding results.
Another area of expertise within the department is the diagnosis and treatment of metabolic disorders: phenylketonuria, maple syrup urine disease, organic acidurias, glycogen storage diseases, fatty acid oxidation defects (MCADD, VLCADD, LCHADD, MADD), lysosomal storage diseases, and others. The clinic is among the few medical centers in the world with extensive experience in treating rare metabolic disorders in children. Young patients with such disorders receive comprehensive care within the department's specialized outpatient clinic.
Key areas of specialization in the department include:
- Gastroenterology
- Diagnostics and treatment of inflammatory bowel diseases: Crohn's disease and ulcerative colitis
- Diagnostics and treatment of short bowel syndrome
- Diagnostics and treatment of celiac disease
- Diagnostics and treatment of gastric, esophageal, and intestinal motility disorders
- Diagnostics and treatment of gastroesophageal reflux disease
- Diagnostics and treatment of food intolerances
- Diagnostics and treatment of congenital malformations of the gastrointestinal tract
- Hepatology
- Diagnostics and treatment of hepatitis B and C
- Diagnostics and treatment of autoimmune hepatitis
- Diagnostics and treatment of congenital malformations of the bile ducts
- Diagnostics and treatment of Wilson's disease
- Metabolic disorders
- Diagnostics and treatment of amino acid metabolism disorders: phenylketonuria, tyrosinemia, maple syrup urine disease, urea cycle disorders, glycine encephalopathy
- Diagnostics and treatment of organic acidurias: methylmalonic aciduria, propionic aciduria, glutaric aciduria type I
- Diagnostics and treatment of carbohydrate metabolism disorders: glycogen storage diseases, galactosemia
- Diagnostics and treatment of energy metabolism disorders: fatty acid oxidation defects, carnitine metabolism disorders, ketolysis defects, mitochondriopathies
- Diagnostics and treatment of vitamin metabolism disorders
- Diagnostics and treatment of lysosomal storage diseases: mucopolysaccharidosis, Pompe disease, Fabry disease, Gaucher disease, Niemann-Pick disease subtypes
- Diagnostics and treatment of cholesterol biosynthesis defects: Smith-Lemli-Opitz syndrome
- Diagnostics and treatment of purine and pyrimidine metabolism disorders
- Other diseases
The range of medical services provided by the department includes:
- Diagnostics
- Comprehensive laboratory diagnostics
- Ultrasound diagnostics
- Functional diagnostics of the gastrointestinal tract
- Esophageal pH-impedance monitoring
- Hydrogen breath test with fructose
- Hydrogen breath test with glucose
- Hydrogen breath test with lactose
- Hydrogen breath test with lactulose
- 13C-urea breath test
- Endoscopic diagnostics
- Gastroscopy
- Colonoscopy
- Gastric, intestinal, and liver biopsy
- Treatment
- Drug therapy
- Endoscopic therapeutic procedures
- Installation of PEG and PEJ feeding tubes
- Balloon dilation and bougiеnage to eliminate stenoses in the upper and lower gastrointestinal tract
- Endoscopic removal of gastric and intestinal polyps
- Latex ligation for the treatment of esophageal varices
- Comprehensive care before and after liver transplantation
- Other medical services
Curriculum vitae
Education and Professional Career
- Study of Medicine at Ludwig Maximilian University of Munich.
- Work in the Department of Pediatric Allergology, Pulmonology and Neonatology.
- Research Internship in Denver, Colorado (2,5 years).
- 2005 Board certification in Pediatric and Adolescent Medicine.
- Professional training in Gastroenterology.
- Since 2007 Senior Physician in the Department of Pediatric Hepatology at the Dr. von Hauner Children's Hospital, as well as the Deputy Head of the Department of Pediatric Gastroenterology at the same hospital.
- Since 2013 Active participation in the development and coordination of the Pediatric Liver Transplant Program, Ludwig Maximilian University of Munich.
- Since October 1, 2017 Head of the Department of Pediatric Gastroenterology and Metabolic Disorders at the Charite University Hospital Berlin.
Photo of the doctor: (c) Charité – Universitätsmedizin Berlin
