Department of Pediatric Oncology and Hematology - Charite University Hospital Berlin
Charite University Hospital Berlin
Berlin, Germany
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Department id #
26128
Prof. Dr. med. Angelika Eggert
Department of Pediatric Oncology and Hematology
Specialized in: pediatric oncology and hematology About the Department of Pediatric Oncology and Hematology at Charite University Hospital Berlin
The Department of Pediatric Oncology and Hematology at the Charite University Hospital Berlin provides comprehensive medical services in its areas of expertise. The department's team of physicians specializes in the treatment of malignant diseases of the hematopoietic system, benign and malignant solid tumors of various locations, congenital and acquired blood clotting disorders, including sickle cell anemia, thalassemia, and hemophilia. More than 50 bone marrow transplantation procedures for children are performed in the department annually – the clinic is one of the leading centers in Germany in this field. Each year, more than 120 children and adolescents receive treatment in the department, most of whom are admitted with particularly complex diseases. Since 2017, the department has had the status of a specialized cancer center with DKG certification, which confirms the outstanding quality of treatment and excellent effectiveness indicators. The medical facility is also certified as a specialized Hemophilia Treatment Center. The department's physicians select the optimal treatment regimen for each child, taking into account the stage of the disease, the patient's age, and general condition. Special attention during treatment is given to psychological support for the child and parents, for whom a cancer diagnosis is associated with tremendous emotional distress. The Head Physician of the department is Prof. Dr. med. Angelika Eggert.
The team of pediatric oncologists focuses on children with leukemias, lymphomas, brain tumors, neuroblastomas, and Ewing's sarcomas. The department is a certified Pediatric Oncology Center with many years of experience in helping children with cancer. Specialists use a multimodal treatment concept that combines several therapeutic methods to achieve complete cure or long-term remission. For leukemia or lymphoma, the main treatment method is chemotherapy, often combined with bone marrow transplantation – these methods are the most effective for this group of diseases. In the case of solid tumors, treatment is usually based on surgical resection of the malignant neoplasm in combination with chemotherapy and/or radiation therapy.
In the field of hematology, the department offers diagnosis and treatment of all diseases of the hematopoietic system in children, with a special emphasis on sickle cell anemia, thalassemia, and Fanconi anemia. It also provides counseling for children with blood clotting disorders: thrombophilia, hemophilia, von Willebrand disease, thrombocytopenia, thrombocytopathy, and others. It is important to note the department's high expertise in the treatment of hemophilia – it is certified by the European Network of Hemophilia Treatment Centers (EUHANET) and the German Hemophilia Treatment Society (DHG). For the treatment of hemophilia in children, effective replacement therapy with blood clotting factor concentrates is provided.
The department's specialists are also justifiably proud of their successful results in the field of bone marrow transplantation in children – more than 50 such procedures are performed here annually. This treatment is used for young patients with relapsed acute lymphoblastic leukemia and acute myeloid leukemia, high-risk neuroblastoma, Fanconi anemia, and immunodeficiency conditions. The department's physicians specialize in autologous and allogeneic bone marrow transplantation: in the first case, the child's own stem cells are transplanted, and in the second case, donor cells are used.
The department's specialization includes:
- Diagnostics and treatment of cancer in children
- Diagnostics and treatment of acute lymphoblastic leukemia
- Diagnostics and treatment of acute myeloid leukemia
- Diagnostics and treatment of lymphomas
- Diagnostics and treatment of brain tumors
- Diagnostics and treatment of neuroblastoma
- Diagnostics and treatment of Ewing's sarcoma
- Diagnostics and treatment of kidney tumors
- Diagnostics and treatment of embryonal tumors
- Diagnostics and treatment of hematopoietic system diseases
- Diagnostics and treatment of sickle cell anemia
- Diagnostics and treatment of thalassemia
- Diagnostics and treatment of Fanconi anemia
- Diagnostics and treatment of Diamond-Blackfan anemia
- Diagnostics and treatment of aplastic anemia
- Diagnostics and treatment of neutropenia
- Diagnostics and treatment of blood clotting disorders
- Diagnostics and treatment of arterial and venous thrombosis
- Diagnostics and treatment of thrombophilia
- Diagnostics and treatment of hemophilia
- Diagnostics and treatment of von Willebrand disease
- Diagnostics and treatment of rare deficiencies of a single blood clotting factor
- Diagnostics and treatment of thrombocytopenia
- Diagnostics and treatment of thrombocytopathies
- Diagnostics and treatment of other diseases
The range of therapeutic services offered by the department includes:
- Surgical resection of solid tumors (in collaboration with pediatric surgeons)
- Chemotherapy
- Radiation therapy
- Bone marrow transplantation
- Autologous bone marrow transplantation
- Allogeneic bone marrow transplantation
- Other treatment methods
Curriculum vitae
- 1993 Study of Medicine at the University of Essen, Germany.
- 1991 - 1993 Doctorate, Institute of Molecular Biology, University of Essen, Germany. Subject: "Preparation and characterization of adenovirus 12-specific polyclonal antibodies directed against specific E1A tumor antigens".
- 1993 - 1997 Resident Physician, Department of Pediatric Hematology and Oncology, University Hospital Essen, Germany.
- 1997 - 2000 Postdoctoral Research Fellow of the Group of Prof. G.M. Brodeur (Deutsche Krebshilfe/Wolfson Career Development Grant), Children’s Hospital of Philadelphia, USA.
- 2000 - 2002 Clinical Fellow, Department of Pediatric Hematology and Oncology, University Hospital Essen, Germany.
- 2003 - 2004 Senior Physician, Department of Pediatric Hematology and Oncology, University Hospital Essen, Germany.
- 2004 Habilitation, University of Duisburg-Essen, Germany. Subject: "Expression and biological function of neurotrophin receptors and receptors of the TNF-family in embryonal tumors".
- 2005 - 2008 C3 Professor of Pediatric Oncology and Deputy Director, Department of Pediatric Hematology and Oncology, University Hospital Essen, Germany.
- 2006 - 2008 Interim Director, Department of Neonatology, Neuropediatrics and Pediatric Intensive Care Medicine.
- Since 2007 Director, University Hospital Essen, Comprehensive Cancer Center (WTZ).
- Since 2008 Head of the Department of Pediatric Hematology, Oncology, Pulmonology and Cardiology, University Hospital Essen, Germany.
- 2009 - 2011 Executive MBA in the International Hospital & Health Care Management, Frankfurt School of Finance and Management, Germany.
- Since 2013 W3 Professor in Pediatrics and Head of the Department of Hematology and Oncology, Charite University Hospital Berlin.
- Acting Head of the Department of Pediatric Gastroenterology and Metabolic Medicine, Charite University Hospital Berlin.
Memberships
- Since 1994 Member of the German Society of Pediatrics.
- Since 1998 Member of the American Association for Cancer Research (AACR).
- Since 2000 Member of the German Society for Pediatric Hematology and Oncology (GPOH).
- Since 2000 Member of the International Society for Pediatric Oncology (SIOP).
Awards
- 1997 Young Investigator Award, International Symposium on Advances in Neuroblastoma Research, City of Bath, United Kingdom.
- 1998 Evans Prize, International Symposium on Advances in Neuroblastoma Research, Philadelphia, USA.
- 2000 Poster Prize of the German Society of Pediatrics.
- 2000 Dr. Odile Schweisguth Prize, SIOP Meeting, Amsterdam, the Netherlands.
- 2000 Research Prize of the WTZ, Essen, Germany.
- 2001 AACR Young Investigator Award, New Orleans, USA.
- 2001 Kind Philipp Prize in Pediatric Oncology, GPOH-Meeting, Frankfurt, Germany.
Photo of the doctor: (c) Charité – Universitätsmedizin Berlin
