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Charite University Hospital Berlin

Department of Pediatric Pulmonology, Immunology and Intensive Care (26129)

Marcus Mall

Prof. Dr. med.

Marcus Mall

Specialized in: pediatric pulmonology, immunology, intensive care

About the department

The Department of Pediatric Pulmonology, Immunology and Intensive Care at the Charite University Hospital Berlin offers the full range of services in these fields. The department positions itself as a maximum care medical facility specializing in the treatment of children and adolescents with allergic diseases, as well as with all acute and chronic respiratory diseases, immunological and autoimmune disorders, cystic fibrosis and rheumatic diseases. The department deals with the treatment of infants, young children and adolescents under the age of 18. Congenital cystic fibrosis is treated in patients of all age groups. Depending on the complexity of the clinical case, the treatment can be provided both on an inpatient and outpatient basis, as well as in a day hospital. The Chief Physician of the department is Prof. Dr. med. Marcus Mall.

The main clinical focuses of the department include:

  • Diagnostics and treatment of allergic reactions
    • Developed treatment regimens for bronchial asthma, allergies and chronic urticaria, including biologic therapy
    • Consultations on allergy prevention 
    • Allergological diagnostics using laboratory diagnostics (specific IgE) and skin tests
    • Nasal provocation tests
    • Oral food provocative tests
    • Structured training of patients (individually and in groups) in bronchial asthma, atopic dermatitis and anaphylaxis
    • Nutrition recommendations in food allergies (diagnostic, therapeutic and preventive diets)
    • All hyposensitization procedures (subcutaneous, sublingual, etc.)
    • Vaccination consultation in relative contraindications
  • Diagnostics and treatment of pulmonological diseases
    • Entire range of lung function testing in children (spirometry, body plethysmography, specific and non-specific provocation methods)
    • Spiroergometry, treadmill stress test
    • Diagnostics of gas exchange disorders
    • Nitric oxide measurements (FeNO) in exhaled air for the diagnostics of bronchial asthma
    • Partial oxygen saturation (SaO2) measurement
    • Sweat test
    • Bronchoscopy (flexible and rigid)
    • All options of imaging diagnostics
  • Diagnostics and treatment of cystic fibrosis (within the specialized center)
    • Sweat test
    • Newborn screening
    • Genetic examinations
    • Functional pulmonary diagnostics
    • Spiroergometry
    • Nutrition consultations
    • Physiotherapy with autogenous drainage and reflex respiratory therapy
    • Oxygenation and non-invasive mask ventilation
    • Ambulatory intravenous antibiotic therapy
    • Psychological and psychosocial support
    • Preparation for lung transplantation and subsequent medical care for children and adults, strict separation of patients according to the range of pathogens
    • Flexible and rigid bronchoscopy with interventional procedures
  • Diagnostics and treatment of immunological diseases
    • Primary immunodeficiencies in children and adults
    • HIV/AIDS in children
    • Especially severe infections due to congenital or acquired immunodeficiency
    • Tuberculosis in children
    • Atypical mycobacterial infection
    • Cytomegalovirus and Epstein–Barr virus
    • All types of influenza
    • Complex infections, including tropical ones
      • Consultations on vaccination
      • Diagnostic assessment of pathological susceptibility to infections in children and adults
      • Inpatient treatment (as part of a day hospital), for example, intravenous immunoglobulin infusion in children and adults
      • Clinical diagnostics and therapy (as part of a day hospital) for children with HIV and other infections
      • Clinical examinations for patients with primary immunodeficiencies or HIV/AIDS
      • Outpatient diagnostics and treatment of children with mycobacterial and other chronic infections
  • Diagnostics and treatment of rheumatic and autoimmune diseases
    • Chronic joint diseases and all types of rheumatism in childhood and adolescence
    • Infectious-associated joint inflammation (for example, Lyme arthritis, reactive arthritis, rheumatic fever)
    • Collagenoses (for example, systemic lupus erythematosus, dermatomyositis, systemic scleroderma)
    • Inflammatory vascular lesions (for example, Kawasaki disease, Takayasu's arteritis)
    • Fever syndromes (for example, familial Mediterranean fever, TRAPS syndrome, PFAPA syndrome)
    • Fever of unknown origin
    • Pain syndromes (for example, chronic regional pain syndrome, fibromyalgia syndrome, reflex dystrophy)
    • Inflammatory bone diseases (for example, chronic recurrent multifocal osteomyelitis)
    • Other inflammatory systemic diseases (for example, Behcet's disease, sarcoidosis)
  • Intensive care
  • Other diseases, diagnostic and therapeutic options

Curriculum vitae

  • ​Since 2007 Attending Physician and Head of Cystic Fibrosis Center, Department of Pediatrics III, University Hospital Heidelberg.
  • Since 2006 Faculty Member of the Molecular Medicine Partnership Unit (MMPU) of the University of Heidelberg and the EMBL.
  • 2005 Junior Group Leader, Department of Pediatrics III, University Hospital Heidelberg.
  • 2004 - 2006 Fellow, Department of Pediatrics III, University Hospital Heidelberg.
  • 2003 - 2004 Assistant Professor, Cystic Fibrosis/Pulmonary Research and Treatment Center, School of Medicine, University of North Carolina, Chapel Hill, USA.
  • 2000 - 2003 Postdoctoral Fellow, Cystic Fibrosis/Pulmonary Research and Treatment Center, School of Medicine, University of North Carolina, Chapel Hill, USA.
  • 1998 - 2000 Resident, Department of Pediatrics, University Hospital Freiburg.
  • 1997 Postdoctoral Fellow, Institute of Physiology, University of Freiburg.
  • 1997 Doctoral thesis (Dr.med.), Institute of Physiology, University of Freiburg.
  • 1990 - 1997 Medical School, University of Freiburg and University College London, Great Britain.

Senior Positions

  • Since 2006 Member of the German Cystic Fibrosis Research Council.
  • Since 2006 Deputy Leader, Workpackage Animal Models, European Coordination Action for Research in Cystic Fibrosis (EuroCareCF).
  • 2004 - 2006 Member of the Scientific Committee for Basic Research, European Cystic Fibrosis Society (ECFS), 29th Annual Conference.

Field of Interests

  • Molecular and cellular pathogenesis of cystic fibrosis and other chronic lung diseases.
  • Transgenic animal models for human diseases.
  • Epithelial ion transport
  • Epithelial defense mechanisms. 
  • Airway inflammation.
  • Identification of novel therapeutic targets and development of novel therapeutic strategies.

Department of Pediatric Pulmonology, Immunology and Intensive Care.
Charite University Hospital Berlin:

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