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Amyotrophic Lateral Sclerosis (ALS) Diagnostics (108235) | Charite University Hospital Berlin - BookingHealth
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Amyotrophic Lateral Sclerosis (ALS) Diagnostics in Charite University Hospital Berlin

Charite University Hospital Berlin

Berlin, Germany
Program id # 108235
Doctor photo
Prof. Dr. med. Matthias Endres
Department of Neurology
Specialized in: neurology
Specialization Curriculum vitae

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • neurological examination
  • laboratory tests:
    • complete blood count
    • biochemical blood test
    • inflammation markers (CRP, ESR)
    • blood coagulation analysis (aPTT, PT, INR)
    • hormone test (TSH)
    • HIV antibodies
    • Wassermann test
  • myelography
  • CT/ MRI (if indicated clinically,
    additional cost is 650/1200 €)
  • cerebrospinal fluid examination
    (if indicated clinically, additional cost is 1800 €)
  • muscle biopsy with histological study
    (if indicated clinically, additional cost is 2000 €)
  • molecular genetic analysis (if indicated clinically)
  • nursing services
  • treatment by chief physician and all leading experts
  • explanation of future recommendations

Required documents

  • Medical records
  • Brain MRI (if available)

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About the department

147 Booking Health patients have already received treatment in the Department of Neurology at the Charite University Hospital Berlin.

99% of patients recommend this hospital and department.

You can read reviews about the quality of the Booking Health service here.

 

According to Focus magazine, the Department of Neurology at the Charite University Hospital Berlin ranks among the top German medical facilities specializing in the treatment of multiple sclerosis, Alzheimer's disease, and Parkinson's disease!

The department offers a full range of diagnostic options and conservative treatments for diseases of the nervous system. The department has 170 beds for patient hospitalization. An important structural section of the department is a specialized Intensive Care Unit (in interdisciplinary collaboration with the Departments of Neurosurgery and Anesthesiology with a focus on intensive surgical care). The department annually treats and diagnoses more than 8,000 inpatients and about 20,000 outpatients. Such indicators show the high quality of medical service and tremendous trust of patients. The department is headed by Prof. Dr. med. Matthias Endres.

The priority fields of clinical practice include the diagnostics and treatment of stroke and neurovascular pathologies, neuroimmunological disorders, multiple sclerosis, motor disorders (for example, Parkinson's disease, essential tremor), neuropathies, and muscular diseases, epilepsy, convulsions, headaches, facial pain syndromes. Thanks to active research activities and exceptional qualifications of the medical personnel, the department also treats rare and extremely complex pathologies, for example, amyotrophic lateral sclerosis, myasthenia, encephalitis, etc.

The diagnostic options of the department include:

Functional diagnostics of the peripheral nervous system

(electroneurography, electromyography, multimodal evoked potentials)

  • Motor and sensory neurography using F-waves
  • Needle electromyography with quantitative analysis of evoked potentials
  • Examinations of neuromuscular connections (synapses)
  • Single-fiber electromyography
  • Reflex testing, including brainstem reflexes
  • Examination of the functionality of small nerve fibers, for example, sympathetic skin reaction
  • Motor evoked potentials
  • Visual and acoustic evoked potential
  • Somatosensory evoked potentials
Electroencephalography
  • Classical electroencephalography
  • Sleep-deprived EEG test
  • EEG for the diagnostics of brain death
Ultrasound diagnostics of the cervical and brain vessels
  • Extra- and intracranial duplex ultrasonography of arteries and veins
  • Extra- and intracranial Doppler ultrasonography
  • Brain perfusion, measurement of cerebral circulation time
  • Transcranial B-mode sonography

Neuropsychological examinations for the diagnostics of cognitive disorders

 

Magnetic resonance imaging for patients with acute or chronic stroke

 

Other diagnostic examinations

 

 

The service range of the department covers the diagnostics and treatment of the following neurological diseases:

Amyotrophic lateral sclerosis

 

Different types of ataxia

 
Movement disorders
  • Parkinson's disease
  • Atypical parkinsonian syndromes (multisystem atrophy, NCV, CBD)
  • Dystonias
  • Tremor
  • Rare motor disorders (caused by metabolic disorders or genetically determined)

Differential diagnostics of movement disorders, including rare ones

 

High-quality additional diagnostics (including MRI, PET, SPECT, CSF testing, skin biopsy, tremor, and movement analysis, neuropsychology, genetic diagnostics, examinations within a Sleep Laboratory)

 

Escalation therapy in Parkinson's disease with indications for deep brain stimulation, drug therapy using Duodopa, and apomorphine therapy

 

Follow-up care after deep brain stimulation and therapy using special pumps

 

Comprehensive drug therapy in Parkinson's disease

 

Outpatient botulinum toxin therapy in dystonia and spasticity

 

Constant monitoring of patient and therapy progress

 

Participation in multicenter researches in pharmacotherapy and deep brain stimulation

 

Dementias and cognitive disorders

 

Encephalitis and paraneoplasias (for example, anti-NMDA receptor encephalitis, limbic encephalitis, paraneoplastic brain inflammation, Morvan's syndrome, etc.)

 

Epilepsy and other convulsive syndromes

 
Headaches
  • Migraines
  • Chronic migraines
  • Tension headaches
  • Cluster headaches

Multiple sclerosis and chronic central nervous system inflammatory diseases 

 

Myasthenia gravis (diagnostics and treatment within a specialized center)

 
Neuromuscular diseases
  • Immunoneuropathies
    • Chronic inflammatory demyelinating polyneuropathy
    • Multifocal motor neuropathy
    • Polyneuropathies of the rheumatic type (for example, polyneuropathies associated with systemic lupus erythematosus) or due to chronic inflammatory bowel diseases
    • Polyneuropathy in monoclonal gammopathy of undetermined significance
    • Guillain-Barré syndrome
  • Muscular diseases
  • Small fiber neuropathy
Neuro-AIDS and HIV neurological disorders
  • HIV-associated neurocognitive deficit: forgetfulness, difficulty concentrating, and impaired fine motor skills
  • HIV-associated neuropathy: sensory processing disorders, pin sensations and pain, usually starting in the toes and feet, and gradually increasing over several weeks
  • HIV-associated vacuolar myelopathy: sensory processing disorders and leg paralysis, bladder dysfunction, and rectal diseases
  • HIV-associated myopathy: muscle aches, muscle weakness, and loss of muscle mass
  • Neurological complications of antiretroviral therapy: emotional disorders, forgetfulness, difficulty concentrating, muscle aches, and muscle weakness
  • Progressive multifocal leukoencephalopathy
Sleep disorders in neurological genesis
  • Sleep problems (for example, sleepwalking)
  • Parasomnia, sleep-related seizures and other movement disorders during sleep
  • Narcolepsy with and without cataplexy and other disorders associated with increased daytime sleepiness
  • Restless legs syndrome
  • Sleep wake rhythm disorders
  • Differential diagnostics of primary sleep disorders and primary mental disorders caused by sleep disorders

Neurological disorders caused by cancers and their therapy

 
Neurovascular disorders
  • Ischemic stroke
  • Hemorrhagic stroke
  • Subarachnoid hemorrhage
  • Cerebral venous thrombosis
  • Intracranial aneurysm
  • Inflammatory cerebrovascular diseases (vasculitis)
    • Urgent diagnostics using MRI, CT, ultrasound, electrophysiological examination
    • "Multimodal monitoring", i.e. continuous recording of blood pressure, ECG, pulse oximetry, respiratory rate, body temperature
    • Intravenous and intra-arterial thrombolysis in acute ischemic stroke
    • Acute cardiological diagnostics and therapy, including echocardiography in collaboration with the Department of Cardiology
    • Emergency treatment of vascular stenosis (in collaboration with the Department of Vascular Surgery (сarotid artery surgery) and interventional radiology (stent implantation))
    • Treatment of intracranial hypertension
    • Botulinum toxin spasticity therapy
    • Immunosuppressive therapy
    • Diagnostics and therapy of strokes, specific brain disorders (neuropsychology)
    • Early rehabilitation (physiotherapy, speech therapy, ergotherapy, and dysphagia treatment)

Other diseases of the nervous system, other medical services

 

​

 

Curriculum vitae

​Education and Professional Сareer

  • Since 2009 Medical Director of the Charité Center 15 for Neurology, Neurosurgery and Psychiatry, Charite University Hospital Berlin.
  • Since 2008 Head of the Department of Neurology at the Charite University Hospital Berlin.
  • Since 2008 W3 Professor, Charite University Hospital Berlin.
  • 2005 - 2008 Lichtenberg Professorship, Interdisciplinary Stroke Research, Volkswagen Foundation, Charite University Hospital Berlin.
  • 2004 - 2007 Senior Physician, Department of Neurology, Charite University Hospital Berlin.
  • 2003 - 2005 Heisenberg Scholarship, German Research Foundation.
  • 2001 Habilitation, Charite University Hospital Berlin.
  • 1998 - 2004 Head of the Research Group on Cerebral Ischemia, Department of Experimental Neurology, Charite University Hospital Berlin.
  • 1998 - 2003 Research Fellow, Department of Neurology, Charite University Hospital Berlin.
  • 1996 - 1998 Research Fellow, Neurology Center, Massachusetts General Hospital, Harvard Medical School, Boston.
  • 1994 - 1996 Assistant Physician, Department of Neurology, University Hospital Lübeck.
  • 1995 Doctoral thesis defense, University of Hamburg.
  • 1988 - 1994 Study of Human Medicine, Ruhr University in Bochum and University of Hamburg.

Positions in Scientific Societies and Organizations

  • Since 2015 Emergency Board Member of the German Stroke Society.
  • 2009 - 2015 Board Member of the German Stroke Society.
  • Since 2008 Board Member, Center for Stroke Research, Charite University Hospital Berlin.
  • 2005 - 2009, 2013 - 2017 Board Member of the International Society of Cerebral Blood Flow and Metabolism (ISCBFM).

Awards and Honorary Memberships

  • Since 2016 Member of the National Academy of Sciences Leopoldina.
  • 2008 Heinrich Pette Prize, German Society of Neurology.
  • 2002 Paul Martini Prize.
  • 2000 Adolf Wallenberg Prize, German Society of Neurology.
  • 1999 Nils Lassen Prize, International Society of Cerebral Blood Flow and Metabolism.
  • 1999 Scientific Prize of the German Stroke Foundation.
  • 1998 Oskar Lapp Research Prize, German Cardiac Society.

Research Focuses

  • Vascular mechanisms of stroke protection 
  • Risk factors and prevention, degeneration and regeneration, as well as depression after a stroke.

Photo of the doctor: (c) Charité – Universitätsmedizin Berlin 

About hospital

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! 

The hospital in Germany provides modern diagnostics and treatment of patients, as well as the training of practicing physicians and scientists. More than half of all German Nobel Prize winners in the field of medicine and physiology, such as Emil von Behring, Robert Koch and Paul Ehrlich, trained and worked in the hospital. The structure of the medical complex includes over 100 specialized departments and institutes, which allows the doctors to guarantee their patients' services in all the existing medical fields. The hospital in Germany has outstanding experience in treating particularly complex clinical cases.

The hospital annually diagnoses and treats more than 152,693 inpatients and about 692,920 outpatients. It also has a huge medical team consisting of 4,225 scientists and doctors and and more than 4,500 nursing staff members who provide top-class medical treatment in Germany. The key task for all specialists of the medical facility is restoring the patient's health or preserving in critical cases. At the same time, the hospital offers a friendly atmosphere, and each patient feels care, respect and sympathy.

The excellent technical medical equipment, highly skilled personnel, availability of innovative diagnostic and treatment techniques, and high ethical standards form a solid foundation for successful clinical and scientific activities. Thus, the hospital is a leading provider of high-quality treatment in Germany.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Charite University Hospital Berlin live in comfortable rooms made of modern design. Each room is equipped with an ensuite bathroom with a toilet and a shower. The standard room furnishing includes an automatically adjustable bed, a bedside table, a wardrobe for storing clothes, a table and chairs for receiving visitors, and a TV. If desired, Wi-Fi access can be provided. The hospital also offers enhanced-comfort rooms.

Meals and Menus

The patient and his accompanying person have a daily choice of three menus. If for any reason, you do not like the food, you will be offered an individual menu. Please inform the medical staff about your dietary preferences before the treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Religious services are available upon request.

Accompanying person

During the inpatient program, an accompanying person may stay with you in a patient room or at the hotel of your choice.

Hotel

During the outpatient program, you can live at a hotel of your choice. Managers will help you to choose the most suitable options.

The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET / CT, angiography, myelography, biopsy and other examinations. Treatment with medications, endoscopic and robotic operations, stereotaxic interventions is carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.

  • Proton therapy
  • CyberKnife treatment
  • Hyperthermic intraperitoneal chemotherapy (HIPEC)
  • PSMA therapy with Lutetium-177
  • Joint replacement in adults and children

These are oncological diseases, benign neoplasms of the brain and spinal cord, heart valve defects, diabetes mellitus and its complications, joint diseases and other pathologies.

  • Neurosurgery
  • Oncology
  • Plastic and reconstructive surgery
  • Interventional radiology
  • Proton therapy (Proton Therapy Center BerlinProtonen)

The medical team includes more than 4,225 highly qualified scientists and doctors.