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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC (639314) | Charite University Hospital Berlin - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.<\/p>\n\n<p style=\"text-align:justify\"><strong>After the completion of the operation<\/strong>, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.<\/p>\n\n<p style=\"text-align:justify\">Finally, the attending physician will evaluate the results of&nbsp;<strong>control examinations<\/strong>, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">MRI\/CT scan (not older than 3 months)<\/li>\n\t<li style=\"text-align: justify;\">Biopsy results (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>clinical history taking<\/li>\n\t<li>review of medical records<\/li>\n\t<li>physical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>general urine analysis<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>tumor markers&nbsp;<\/li>\n\t\t<li>inflammation indicators (CRP, ESR)<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>abdominal ultrasound scan<\/li>\n\t<li>CT scan\/MRI or PET-CT of abdomen<\/li>\n\t<li>preoperative care<\/li>\n\t<li>cytoreductive surgery to remove visible tumors<br \/>\n\tinside the abdomen and HIPEC<\/li>\n\t<li>histological and immunohistochemical<br \/>\n\texamination of removed tissues<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>cost of essential medicines<\/li>\n\t<li>nursing services<\/li>\n\t<li>stay in the hospital with a full board<\/li>\n\t<li>accommodation in a 2-bedroom ward<\/li>\n\t<li>elaboration of further recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align:justify\"><strong>During the first visit<\/strong>, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. 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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC in Charite University Hospital Berlin

Charite University Hospital Berlin

Berlin, Germany
Program id # 639314
Doctor photo
Prof. Dr. med. Jens-Uwe Blohmer
Department of Adult and Pediatric Gynecology, Mammology
Specialized in: adult and pediatric gynecology, mammology

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)

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About the department

According to the Focus magazine, the Department of Adult and Pediatric Gynecology, Mammology at the Charite University Hospital Berlin ranks among the top German medical facilities in the fields of its specialization!

The department offers all options of modern medicine for the diagnostics and treatment of diseases of the female reproductive organs and breast. Of particular interest is the treatment of cancers of the female reproductive organs and breast (certification of the German Cancer Society). In addition, the department's doctors have exceptional competence in the treatment of gynecological problems in children of all age groups, including surgical correction of congenital malformations of the reproductive organs. The department is proud of its outstanding treatment results achieved thanks to the professional skills of doctors and excellent technical base.

The Head Physician of the department is Prof. Dr. med. Jens-Uwe Blohmer, who is well known in professional medical circles and among patients all over the world. The specialist has been working in gynecology and mammology for over 16 years. During this time, he has performed more than 10,000 interventions for breast cancer and thousands of surgical procedures to treat female genital malignancies. Dr. Blomer is rightfully proud of his qualifications in laparoscopic and robot-assisted surgery. The professor is the author and co-author of books, as well as more than 220 publications in medical print media and on the Internet.

Cancer pathologies of the female reproductive area are treated in interdisciplinary cooperation using reliable and effective therapeutic techniques. The department's gynecologists specialize in the treatment of ovarian fallopian tube, peritoneal, cervical, labial cancers and rare cancers. This field is certified by the European Society of Gynecological Oncology and the German Cancer Aid. Each clinical case is considered on an individual basis, after which an optimal treatment strategy is developed. If surgical intervention is required, the preference is always given to sparing minimally invasive surgery.

Also, the department's doctors are engaged in the treatment of benign gynecological diseases, for example, endometriosis, uterine fibroids, benign breast changes. An integral part of clinical practice is the provision of medical care to girls and teenage girls with diseases of the gynecological range. The focus in this field is on the surgical correction of reproductive malformations (for example, vaginal agenesis, uterine malformations), treatment of infections, puberty disorders, menstrual disorders, malignant neoplasms, etc.

The priority of the department's mammologists is the treatment of breast cancer, including hereditary types. The therapeutic options include comprehensive diagnostics, accurate planning of individual treatment, conduction of all necessary therapeutic measures, follow-up care. In the case of breast resection, the doctors perform modern types of plastic surgery using implants and patient's own tissues. Psychological care is also an important component of therapy, since the detection of cancer is always associated with fears and negative emotions.

The service range of the department includes:

Diagnostics and treatment of cancer of the female genital organs
  • Uterine cancer
  • Cervical cancer
  • Ovarian cancer
  • Vulvar cancer
  • Fallopian tube cancer
  • Labial cancer
  • Rare types of gynecological tumors
  • Gynecological neuroendocrine tumors (treatment within the interdisciplinary center)
  • Gynecological sarcomas (treatment within the interdisciplinary center)
Diagnostics and treatment of breast cancer 
Consultations on hereditary breast and ovarian cancers 
Diagnostics and treatment of endometriosis 
Diagnostics and treatment of uterine fibroids
  • Radiological therapeutic techniques
    • MRI-guided focused ultrasound therapy
    • Uterine fibroid embolization
  • Surgical treatment
    • Uterine fibroid resection
    • Uterine resection
    • Combined treatment using embolization and surgical intervention
Diagnostics and treatment of gynecological problems in children and adolescents
  • Congenital malformations of the reproductive organs in girls
  • Infections
  • Puberty disorders
  • Menstrual cycle disorders
  • Tumors of the reproductive organs
  • Psychological care (for example, after sexual abuse, in sexual differentiation disorders, anorexia, bulimia, tumors)
  • Prevention: intimate hygiene, sex education, contraception, HPV vaccination
Diagnostics and treatment of other diseases of the female reproductive organs, mammary gland 

Curriculum vitae

  • 2000 Habilitation in Gynecology and Obstetrics, Charite University Hospital Berlin, Senior Physician of the Department of Gynecology at the Charite, Berlin.
  • 2004 - 2014 Head of the Breast Center at the Sankt Gertrauden-Krankenhaus Clinic, Berlin.
  • 2005 - 2014 Chief Physician of the Department of Obstetrics and Gynecology at the Sankt Gertrauden-Krankenhaus Clinic, Berlin.
  • Since 1 September 2014, Head of the Department of Adult and Pediatric Gynecology, Mammology, Charite University Hospital Berlin.

Clinical Focuses

  • Breast cancer: diagnostics, surgical treatment, chemotherapy, drug treatment with monoclonal antibodies and hormones.
  • Breast reconstruction: installation of implants, reconstruction of muscles with the help of the patient’s own tissues.
  • Intraoperative radiotherapy for the treatment of breast cancer.
  • Three-dimensional ultrasound examination of the mammary glands and ovaries.
  • Treatment of ovarian, uterine, cervical cancer: diagnostics, surgical treatment, drug therapy and follow-up.

Special Clinical Focuses

  • Treatment of gynecological cancers (chemotherapy and surgery).
  • Treatment of benign gynecological diseases.
  • Laparoscopy.
  • Laser therapy for malignant diseases of the female genital organs.
  • Radical hysterectomy.
  • Partial hysterectomy.

Photo of the doctor: (c) Charité – Universitätsmedizin Berlin

Sources:

Vaidam.com - For Medical Travellers

Charité – Universitätsmedizin Berlin

PubMed, National Library of Medicine


About hospital

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! 

The hospital in Germany provides modern diagnostics and treatment of patients, as well as the training of practicing physicians and scientists. More than half of all German Nobel Prize winners in the field of medicine and physiology, such as Emil von Behring, Robert Koch and Paul Ehrlich, trained and worked in the hospital. The structure of the medical complex includes over 100 specialized departments and institutes, which allows the doctors to guarantee their patients' services in all the existing medical fields. The hospital in Germany has outstanding experience in treating particularly complex clinical cases.

The hospital annually diagnoses and treats more than 152,693 inpatients and about 692,920 outpatients. It also has a huge medical team consisting of 4,225 scientists and doctors and and more than 4,500 nursing staff members who provide top-class medical treatment in Germany. The key task for all specialists of the medical facility is restoring the patient's health or preserving in critical cases. At the same time, the hospital offers a friendly atmosphere, and each patient feels care, respect and sympathy.

The excellent technical medical equipment, highly skilled personnel, availability of innovative diagnostic and treatment techniques, and high ethical standards form a solid foundation for successful clinical and scientific activities. Thus, the hospital is a leading provider of high-quality treatment in Germany.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Charite University Hospital Berlin live in comfortable rooms made of modern design. Each room is equipped with an ensuite bathroom with a toilet and a shower. The standard room furnishing includes an automatically adjustable bed, a bedside table, a wardrobe for storing clothes, a table and chairs for receiving visitors, and a TV. If desired, Wi-Fi access can be provided. The hospital also offers enhanced-comfort rooms.

Meals and Menus

The patient and his accompanying person have a daily choice of three menus. If for any reason, you do not like the food, you will be offered an individual menu. Please inform the medical staff about your dietary preferences before the treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Religious services are available upon request.

Accompanying person

During the inpatient program, an accompanying person may stay with you in a patient room or at the hotel of your choice.

Hotel

During the outpatient program, you can live at a hotel of your choice. Managers will help you to choose the most suitable options.

The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET / CT, angiography, myelography, biopsy and other examinations. Treatment with medications, endoscopic and robotic operations, stereotaxic interventions is carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.

  • Proton therapy
  • CyberKnife treatment
  • Hyperthermic intraperitoneal chemotherapy (HIPEC)
  • PSMA therapy with Lutetium-177
  • Joint replacement in adults and children

These are oncological diseases, benign neoplasms of the brain and spinal cord, heart valve defects, diabetes mellitus and its complications, joint diseases and other pathologies.

  • Neurosurgery
  • Oncology
  • Plastic and reconstructive surgery
  • Interventional radiology
  • Proton therapy (Proton Therapy Center BerlinProtonen)

The medical team includes more than 4,225 highly qualified scientists and doctors.