About the Department of Reproductive Medicine and Andrology at University Hospital Halle (Saale)
The Department of Reproductive Medicine and Andrology at the University Hospital Halle (Saale) offers a full range of medical services in its areas of specialization at the highest level of university medicine. The department provides qualified medical care for patients with infertility, impaired sex hormone synthesis, and sexual disorders, including erectile dysfunction. A unique service of the department is egg and sperm cryopreservation for delayed pregnancy planning, for example, after oncopathology. The main focus of the department's physicians is the treatment of infertility using modern assisted reproductive technologies, the most popular of which are intrauterine insemination, in vitro fertilization, and intracytoplasmic sperm injection. The health of patients is in the safe hands of a highly professional medical team, consisting of experienced gynecologists, endocrinologists, andrologists, and experts in reproductive medicine. Most of the diagnostic and therapeutic services of the department are provided on an outpatient basis without mandatory hospitalization. The medical facility is a member of the German Society for Reproductive Medicine (DGRM) and the German Society of Andrology (DGA), so the standards of medical care prescribed by these societies are strictly followed here. The Head Physician of the department is Prof. Dr. med. Hermann Behre.
The main focus of the department's specialists is the treatment of infertility in women and men. Infertility is diagnosed when a couple is unable to conceive a child after 12 months of regular sexual intercourse without the use of contraception. The therapeutic process begins with a comprehensive diagnosis, which includes an analysis of the medical history of both partners, extensive laboratory tests, gynecological and urological examinations, and ultrasound scans; men also undergo a spermogram, a test to assess the quality and quantity of sperm. Based on the results of the preliminary diagnosis, the reason for the inability to conceive a child is determined: pregnancy may not occur due to female factor infertility (for example, decreased egg quality due to age-related changes, anovulatory cycle, fallopian tube obstruction, uterine fibroids, endometriosis, etc.), male factor infertility (for example, insufficient sperm production, impaired sperm transport through the vas deferens, or azoospermia), or a combination of both. Before starting the treatment, the doctors of the department conduct an individual consultation with the couple, during which they explain the possible treatment options, their advantages, and the prognosis for the desired pregnancy, after which a joint decision is made on the best option.
When infertility is diagnosed against the background of menstrual disorders in women, the department's reproductive medicine specialists use only a course of drug treatment. In more complex clinical situations, the specialists of the medical facility often resort to assisted reproductive technologies, among which intrauterine insemination (IUI), in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI) are particularly effective. Intrauterine insemination is a procedure in which specially prepared sperm are introduced into the uterine cavity. The therapeutic manipulation is performed during ovulation, which can be stimulated either with hormonal drugs or naturally. A prerequisite for the IUI procedure is that the fallopian tubes are patent. In case of tubal patency problems, ovulation disorders, or poor sperm quality of the partner, in vitro fertilization (IVF) is more appropriate. The essence of IVF is that the fertilization of an egg by a sperm occurs outside the woman's body, in a laboratory. IVF begins with hormonal stimulation of the ovaries to obtain multiple oocytes, after which the mature oocytes are retrieved by follicular puncture, fertilized in the laboratory, and transferred into the uterine cavity to achieve pregnancy. The IVF method can be indicated for both female and male infertility. The success rate of IVF treatment is quite high, as 35-40% of patients become pregnant at the first attempt. The department also offers intracytoplasmic sperm injection (ICSI), a type of IVF in which a mature sperm is artificially introduced into a mature egg. This technique is used in cases of severe male factor infertility, when independent fertilization with sperm is difficult or impossible for various reasons.
An integral part of the department's daily clinical practice is the diagnosis and treatment of hormonal disorders in women such as menstrual irregularities, hirsutism (excessive facial or body hair growth), premenstrual syndrome, hyperprolactinemia, and ovarian exhaustion syndrome. The department also has extensive experience in treating men with hypogonadism, a condition in which testosterone levels are low due to insufficient testicular function. The department's specialists perform testosterone replacement therapy to treat this condition.
The department also successfully treats sexual disorders in both men and women. Of particular interest in this area is treatment for men with erectile dysfunction (impotence). This andrological disease affects the ability to achieve or maintain an erection necessary for sexual intercourse. During the diagnosis of suspected impotence, doctors analyze the patient's medical history and perform laboratory tests, cavernosography, ultrasound scans, and psychological tests. In most cases, psychotherapy and drug treatment are sufficient to normalize erectile function. However, in the clinical practice of the doctors of the department, there are also complex cases of impotence that require vacuum therapy, intracavernosal injections, and phalloprosthetics (an operation in which the cavernous bodies of the penis are replaced by special implants).
The main clinical focuses of the department are as follows:
- Diagnostics and treatment of infertility
- Therapeutic offer for women
- Hormonal stimulation to normalize the menstrual cycle in order to achieve regular ovulation and prepare the uterus for pregnancy
- Minimally invasive removal of benign tumors (uterine fibroids, endometrioid cysts, dermoids, etc.) and laparoscopic removal of adhesions
- Assisted reproductive technologies
- Intrauterine insemination (IUI)
- In vitro fertilization (IVF)
- Intracytoplasmic sperm injection (ICSI)
- Therapeutic offer for men
- Drug stimulation for normalization of hormonal levels
- Antibiotic therapy for inflammation of the testicles, epididymis, prostate gland, and seminal vesicles
- Therapeutic offer for women
- Diagnostics and treatment of hormonal imbalances
- Diagnostics and treatment of hormonal imbalances in women
- Diagnostics and treatment of menstrual disorders
- Diagnostics and treatment of hirsutism
- Diagnostics and treatment of premenstrual syndrome
- Diagnostics and treatment of hyperprolactinemia
- Diagnostics and treatment of premature ovarian failure
- Diagnostics and treatment of hormonal imbalances in men
- Diagnostics and treatment of hypogonadism
- Diagnostics and treatment of hormonal imbalances in women
- Diagnostics and treatment of problems in sexual life in men and women
- Diagnostics and treatment of erectile dysfunction in men
- Medical care for psychosexual problems
- Medical care for transsexualism
- Germ cell cryopreservation
- Oocyte deep freezing (pronuclear stage) after successful in vitro fertilization
- Sperm cryopreservation in case of poor initial data before planned IVF or ICSI
- Sperm deep freezing and storage to preserve fertility when radiation/chemotherapy is required for cancer
- Testicular tissue cryopreservation before sperm extraction (TESE) and ICSI in the presence of azoospermia
- Ovarian tissue or oocyte cryopreservation for oncological diseases in women who want to have children in the future
- Other medical services
Curriculum vitae
Higher Education and Professional Career
- 1980 - 1987 Medical studies, Westphalian Wilhelm University of Muenster; internships at the Middlesex Hospital Medical School (London, UK), the University of Washington School of Medicine (Seattle, WA, USA), and Harvard Medical School (Boston, MA, USA).
- 1987 Medical license.
- 1987 - 1988 Max Planck Fellowship at the Clinical Research Group for Reproductive Medicine in Muenster.
- 1988 Thesis defense, summa cum laude, and doctorate.
- 1988 - 2000 Senior Physician, Institute for Reproductive Medicine in the Department of Gynecology and Obstetrics at the University Hospital Muenster; Associate Professor, Westphalian Wilhelm University of Muenster; Head of the Section for Infertility Treatment with Assisted Reproductive Technologies at the University Hospital Muenster.
- 1995 Habilitation and Venia legendi in Andrology and Reproductive Medicine, Faculty of Medicine, Westphalian Wilhelm University of Muenster.
- Since 2000 Professor, Faculty of Medicine, Westphalian Wilhelm University of Muenster.
- Since 2007 Head Physician, Department of Reproductive Medicine and Andrology, University Hospital Halle (Saale).
- Since 2007 Chairman of the Ethics Committee of the Faculty of Medicine of the Martin Luther University Halle-Wittenberg.
Qualifications
- Board certification in Gynecology and Obstetrics.
- Board certification in Urology and Andrology.
- Specialization in Gynecological Endocrinology and Reproductive Medicine.
Clinical Interests
- Application of modern assisted reproductive technologies: in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and testicular sperm extraction (TESE).
- Recombinant hormone therapy for infertility in hypogonadotropic hypogonadism.
- Modern methods of testosterone replacement therapy for hypogonadism.
Clinical Interests
- Single nucleotide polymorphisms of gonadotropins and gonadotropin receptors and their relevance in the treatment of infertility.
- Optimization of ovulation induction protocols using assisted reproductive technologies.
- Molecular causes of infertility in men and women.
Memberships in Professional Societies
- German Society for Reproductive Medicine (DGRM).
- German Society of Andrology (DGA).
- German Society for Gynecology and Obstetrics (DGGG).
- Working Group of the Centers for Reproductive Medicine at the University Hospitals of the German Society for Reproductive Medicine (DGRM) and the German Society for Gynecology and Obstetrics (DGGG).
- German Society of Endocrinology (DGE).
- European Academy of Andrology (EAA).
- European Society of Human Reproduction and Embryology (ESHRE).
Photo of the doctor: (c) Universitätsklinikum Halle (Saale)