About the Department of Pediatric Hematology, Oncology, Endocrinology, Rheumatology and Neurology at University Hospital Halle (Saale)
The Department of Pediatric Hematology, Oncology, Endocrinology, Rheumatology and Neurology at the University Hospital Halle (Saale) offers a full range of modern diagnostics and treatment in its areas of specialization. It provides medical care for young patients with benign and malignant diseases of the hematopoietic system, solid tumors of various localizations, endocrine diseases, including diabetes mellitus, rheumatic diseases, and pathologies of the nervous system. The department's team of doctors uses only highly effective and reliable treatment methods, focusing on current international clinical protocols. Bone marrow transplantation in children is successfully performed here (JACIE certification). The department has created the most comfortable conditions for young patients: there are play areas where children can take a break from the therapeutic process. The outstanding achievements of the medical facility in the field of treatment of pediatric diseases are confirmed by numerous quality certificates, such as the ISO 9001:2015 certificate, the ClarCert certificate, the certificate of the German Cancer Society (DKG), the certificate of the German Diabetology Society (DDG), the certificate of the Association for Obesity in Children and Adolescents (AAKJ), and the certificate of the German Society for Clinical Neurophysiology and Functional Imaging (DGKN). The department is headed by Prof. Dr. med. Simone Hettmer.
Treatment of benign and malignant blood diseases is one of the priority areas of work of the department's specialists. Of particular interest is the treatment of blood cancers such as acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, juvenile myelomonocytic leukemia, and other types of oncology. Pediatric oncologists have all the tools in their arsenal to fight blood cancers. The first-line treatment is chemotherapy, the duration and intensity of which are determined individually. If clinically indicated, immunotherapy, targeted therapy, and radiation therapy may also be used. In complex cases, the department's physicians recommend autologous or allogeneic bone marrow transplantation. The procedure is performed in a specialized center certified according to the standards of the European organization JACIE. The department is also certified by the German Cancer Society (DKG) in the treatment of childhood cancer, which guarantees compliance with the highest medical standards in this specialty.
The department provides competent medical care for children with benign blood diseases, with a special emphasis on the treatment of hemoglobinopathies (for example, thalassemia and sickle cell anemia) and blood clotting disorders (for example, hemophilia A and B, von Willebrand disease, factor VII deficiency, and thrombocytopathy). The therapeutic process begins with the examination of the child, the results of which are used to plan the treatment tactics. If the diagnosis of hemoglobinopathy is confirmed, drug therapy, special diet, blood transfusion and red cell mass transfusion are prescribed, while in complex clinical situations bone marrow transplantation from a related or unrelated donor may be required. If a child is diagnosed with a coagulation disorder, drug therapy, intravenous administration of coagulation factor concentrates, and other therapeutic measures are used.
The department has a competent team of pediatric endocrinologists. Doctors of this specialty consult young patients with short stature, tall stature, obesity, precocious puberty and delayed puberty, bone metabolism disorders, diabetes mellitus, and diseases of the thyroid, adrenal, and pituitary glands. Hormone therapy is used here to treat endocrine disorders. Children with diabetes mellitus receive comprehensive medical care, including insulin therapy using the most advanced insulin pumps, blood glucose control using high-precision continuous monitoring systems, diet therapy, exercise therapy, and psychological support.
The medical facility also diagnoses and treats rheumatic diseases in children. The doctors of the department mainly deal with juvenile idiopathic arthritis, Lyme disease, chronic nonbacterial osteomyelitis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma, vasculitis and Kawasaki disease. Treatment includes drug therapy with various classes of drugs (nonsteroidal anti-inflammatory drugs, corticosteroids, biologics, etc.), physiotherapy procedures, diet therapy, and occupational therapy.
Pediatric neurology focuses on the medical care of children and adolescents with acute and chronic disorders of the peripheral and central nervous systems, as well as neuromuscular disorders. The pediatric neurologists in the department are highly qualified in the treatment of epilepsy and chronic headaches in children. In order to maximize the comfort of young patients, diagnostic and therapeutic procedures are performed on an outpatient basis, with hospitalization required only in complex clinical situations. The department performs all currently available diagnostic examinations to assess the development and function of the nervous system in children, including awake and asleep electroencephalography, long-term EEG, electromyography, electroneuromyography, computed tomography, and magnetic resonance imaging. As for the treatment, children most often receive drug therapy combined with physiotherapy. Young patients with cerebral palsy and spasticity undergo botulinum therapy.
The department's clinical focuses include the following:
- Hematology and oncology
- Diagnostics and treatment of malignant blood diseases
- Diagnostics and treatment of acute lymphoblastic leukemia
- Diagnostics and treatment of acute myeloid leukemia
- Diagnostics and treatment of chronic myeloid leukemia
- Diagnostics and treatment of juvenile myelomonocytic leukemia
- Diagnostics and treatment of benign blood diseases
- Diagnostics and treatment of hemoglobinopathies: thalassemia, sickle cell anemia, etc.
- Diagnostics and treatment of blood clotting disorders: hemophilia A and B, von Willebrand disease, factor VII deficiency, thrombocytopathy, etc.
- Diagnostics and treatment of solid malignant tumors
- Diagnostics and treatment of malignant blood diseases
- Endocrinology
- Diagnostics and treatment of short stature
- Diagnostics and treatment of tall stature
- Diagnostics and treatment of obesity
- Diagnostics and treatment of precocious puberty and delayed puberty
- Diagnostics and treatment of bone metabolism disorders
- Diagnostics and treatment of diabetes mellitus
- Diagnostics and treatment of thyroid diseases
- Diagnostics and treatment of adrenal diseases
- Diagnostics and treatment of pituitary diseases
- Rheumatology
- Diagnostics and treatment of juvenile idiopathic arthritis
- Diagnostics and treatment of Lyme disease
- Diagnostics and treatment of chronic nonbacterial osteomyelitis
- Diagnostics and treatment of systemic lupus erythematosus
- Diagnostics and treatment of juvenile dermatomyositis
- Diagnostics and treatment of systemic scleroderma
- Diagnostics and treatment of vasculitis
- Diagnostics and treatment of Kawasaki syndrome
- Neurology
- Diagnostics and treatment of epilepsy
- Diagnostics and treatment of multiple sclerosis
- Diagnostics and treatment of chronic headaches
- Diagnostics and treatment of cerebral palsy
- Diagnostics and treatment of spasticity
- Diagnostics and treatment of traumatic brain injuries
- Diagnostics and treatment of infectious diseases of the brain and spinal cord
- Other medical services
Curriculum vitae
Since 1 March 2024, Prof. Dr. med. Simone Hettmer has been Head Physician of the Department of Pediatric Hematology, Oncology, Endocrinology, Rheumatology and Neurology at the University Hospital Halle (Saale) and Professor for Pediatric Oncology at the Faculty of Medicine of the Martin Luther University Halle-Wittenberg. Prof. Hettmer graduated from the Faculty of Medicine of the Eberhard Karl University of Tuebingen, where she received her doctorate in 1999. She then worked as an Assistant Physician at the University Hospital Bonn. In 2001, Dr. Simone Hettmer received a fellowship from the German Childhood Cancer Foundation (Deutsche Kinderkrebsstiftung) in Washington, USA, where she conducted research in the laboratory for two years. Since 2003, she has held clinical and academic positions at Harvard University and its academic hospitals, Massachusetts General Hospital, and the Dana-Farber Children's Cancer and Blood Disorders Center in Boston. In 2006, Prof. Simone Hettmer was board certified in Pediatric Hematology and Oncology in the United States, followed by her board certification in these clinical areas in Germany in 2011. Dr. Hettmer returned to Germany in 2014 and took up a position as a Senior Physician in the Department of Pediatric and Adolescent Medicine at the University Hospital Freiburg. In 2016, she completed her habilitation at the University Hospital Freiburg and received her Venia legendi in Pediatric Hematology and Oncology.
Photo of the doctor: (c) Universitätsklinikum Halle (Saale)