Diagnostic tests for clear cell renal carcinoma in Knappschaft Hospital Dortmund

About the department

According to the Focus magazine, the Department of Adult and Pediatric Urology, Urogynecology, Prostate Surgery and Andrology at the Knappschaft Hospital Dortmund has been ranking among the top German medical facilities specializing in prostate cancer treatment for many years in a row!

The department offers the full range of high-precision diagnostic examinations, conservative and surgical treatments for diseases of the male reproductive organs, urinary system in both men and women. The department admits not only adults, but also children with urologic diseases. The priority field of ​​clinical practice is prostate cancer treatment. The high quality of medical services in this field is certified by the German Cancer Society. The department's highly qualified doctors successfully perform surgical procedures to treat prostate cancer (prostatectomy) using the innovative da Vinci Surgical System, which allows them to preserve erectile function, and also excludes the development of urinary disorders, which often develop after classical open surgery. Each patient of the department benefits from an individual treatment regimen with due consideration of his particular needs and wishes. The department is headed by Dr. med. Stefan Orth.

Prostate cancer is the most common diagnosis among men admitted to the department. The diagnostics and treatment of prostate cancer is carried out in the specialized Prostate Center, which is part of the department. The treatment of prostate cancer is carried out in an interdisciplinary collaboration of specialists from all related fields, who cooperatively elaborate the treatment tactics for achievement of a complete cure for the patient or a long-term remission. During the therapeutic process, the doctors use the very latest treatment methods in order to ensure a perfect result even in particularly complex clinical cases. It should be noted that the department's physicians regularly demonstrate high treatment success rates, while the frequency of cancer recurrences is very low. It is not surprising that the department admits not only German citizens for treatment, but also many patients from other European countries and far abroad.

The key to the successful treatment is high-quality diagnostics, and therefore the department has state-of-the-art devices for MRI and CT scanning, color duplex sonography, biopsy, including MRI-guided fusion biopsy. The comprehensive diagnostics allows the interdisciplinary tumor board to thoroughly assess the clinical case and select the set of treatment methods that will give the best result for the patient. In some cases, the doctors use only conservative methods, such as chemotherapy, hormone therapy, brachytherapy (a type of radiation therapy, in which a radiation source is placed into the prostate gland), active surveillance, if the pathology does not cause any symptoms and progresses very slowly. However, in most cases, prostate cancer requires prostatectomy. When choosing surgical treatment methods, the doctors always prefer minimally invasive interventions using the da Vinci Surgical System. Prostatectomy using the da Vinci Surgical System involves only a few small skin incisions, through which, under the guidance of a qualified surgeon, who is always at a special console, the special miniature surgical instruments are inserted using the robotic "slave manipulators". One of the "slave manipulators" of the robotic device has a fixed camera, which is inserted into the site of ​​the operating field. The camera transmits images of the surgical field, which are displayed on a large screen with the possibility of multiple zooming. Thus, the surgeon can clearly see the smallest anatomical structures, thereby excluding damage to healthy tissue located near the pathological focus. The da Vinci "slave manipulators" provide a huge range of motion that the surgeon is unable to perform due to the physical capabilities of the human hand. In addition, robotic surgery eliminates the natural physiological hand tremors due to anxiety and other factors. Small skin incisions contribute to the rapid recovery of the patient after surgery, as well as significantly reduce the intake of painkillers due to the mild pain syndrome. Robot-assisted prostatectomy preserves erectile function and avoids damage to the bladder, which is often not possible to achieve with classical surgery.

The treatment of benign prostatic hyperplasia is also within the competence of the department's doctors. At the initial stages of the pathology, drug therapy using modern medications is sufficient in most cases. If drugs are ineffective, the department's medical team uses bloodless laser techniques (GreenLight laser) and minimally invasive surgical techniques – transurethral resection of the prostate (TUR), transurethral resection in saline (TURiS), open or laparoscopic adenomectomy. The selection of the surgical technique is determined strictly on an individual basis.

The department's specialists in the field of urogynecology deal with the treatment of all types of urinary incontinence in men and women, as well as with the treatment of pelvic organ prolapse in women. The department's doctors have rich and successful experience in open, laparoscopic and robot-assisted interventions for the treatment of urogynecologic diseases. The therapy for urinary incontinence in women is most often performed using the TVT and TVT-O sling procedures. Since 2004, the department has also been treating urinary incontinence by injecting botulinum toxin A into the bladder muscles. The innovative Advance® Band and Remeex®-MRS systems are used for  the elimination of mild and moderate urinary incontinence in men. In the case of particularly severe types of urinary incontinence in men,the doctors perform surgery to implant an artificial urinary sphincter AMS 800®.

Andrology is also an important focus of the department's c​​linical work. The department's andrologists specialize in the diagnostics and treatment of erectile dysfunction, hormonal disorders in men, infertility, benign diseases of the testicles and penis. The patients diagnosed with infertility are offered such procedures as testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI). The most commonly used treatments for erectile dysfunction are drug therapy, vacuum pump therapy and SKAT therapy. The doctors in this field also perform male sterilisation, penile straightening surgery in the case of penile curvature (for example, Nesbit's procedure), foreskin removal (circumcision in phimosis) and other interventions.

The department's service range is complemented by the diagnostics and treatment of urologic diseases in children. The specially trained team of doctors with deep knowledge not only in the field of urology, but also in the field of pediatrics takes care of the health of young patients. Most of the diagnostic and therapeutic procedures for pediatric urologic diseases are performed on an outpatient basis, so the child does not need inpatient hospitalization. The most common diseases of the genitourinary system in children include undescended testes, polycystic kidney disease, renal duplication, hypospadias, urethral meatal stenosis, enuresis and infections of the urinary tract. The department's pediatric urologists have excellent qualifications in their field, and thus provide young patients with the highest quality treatment.

The main clinical focuses of the department include:

• Diagnostics and treatment of prostate cancer
  • Active surveillance
  • Chemotherapy
  • Hormone therapy
  • Brachytherapy
  • da Vinci robotic prostatectomy
• Diagnostics and treatment of benign prostatic hyperplasia
  • Drug treatment
  • GreenLight laser therapy
  • Transurethral resection of prostate adenoma (TUR)
  • Transurethral resection in saline (TURis)
  • Open or laparoscopic adenomectomy
• Diagnostics and treatment of pelvic organ prolapse, urinary incontinence in men and women
  • TVT and TVT-O sling interventions in women
  • Botulinum toxin A injections into the bladder muscles in women
  • Treatment of urinary incontinence in men with the innovative Advance® Band and Remeex®-MRS systems
  • Surgery to implant an artificial urinary bladder sphincter AMS 800® (only for particularly severe forms of urinary incontinence in men)
• Diagnostics and treatment of diseases of the kidneys, ureters, bladder and urethra, including cancer
  • Minimally invasive surgery
  • da Vinci robot-assisted surgery
  • Treatment of kidney, ureter and bladder stones using extracorporeal shock wave lithotripsy, ureterorenoscopy, percutaneous nephrolitholapaxy, and mini-percutaneous nephrolitholapaxy
• Diagnostics and treatment of andrological disorders
  • Infertility treatment (in cooperation with the Department of Reproductive Medicine)
    • Testicular sperm extraction (TESE)
    • Intracytoplasmic sperm injection (ICSI)
  • Erectile dysfunction treatment
    • Drug therapy
    • Vacuum pump applications
    • SKAT therapy
  • Sterilization surgery for men
  • Penile straightening surgery in the case of penile curvature (for example, Nesbit's procedure)
  • Foreskin removal (circumcision in the case of phimosis)
• Diagnostics and treatment of urologic diseases in children (in most cases on an outpatient basis)
  • Drug treatment
  • Surgical treatment
• Other medical services