Living-related liver transplantation
Baskent University Hospital Istanbul
Istanbul, Turkey
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Program id #
653911
Prof. Dr. med. Ahmet Serdar Karaca
Department of Kidney and Liver Transplantation in Adults and Children
Specialized in: kidney and liver transplantation in adults and children The program includes:
- Initial presentation in the clinic
- clinical history taking
- physical examination
- review of medical records
- laboratory tests:
- complete blood count
- general urine analysis
- biochemical analysis of blood
- tumor marker
- TSH-basal, fT3, fT4
- HLA typing/ PRA
- hepatitis (B,C) serology, HIV, CMV, EBV, TPHA
- tuberculin testing
- indicators of inflammation
- indicators blood coagulation
- ultrasound/MRI/CT of the abdomen
- x-ray of the chest
- lung function tests/ EKG
- liver vessels angiography
- a full range of donor examinations
- preoperative care
- transplantation
- symptomatic treatment
- control examinations
- the cost of essential medicines and materials
- the costs of donor operative treatment and accommodation
- nursing services
- full hospital accommodation
- explanation of future recommendations
How program is carried out
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About the department
The Department of Kidney and Liver Transplantation in Adults and Children at the Baskent University Hospital Istanbul offers the full range of services in its area of competence. The department's specialists successfully perform kidney and liver transplant surgery in patients suffering from chronic renal failure, chronic liver failure, liver cirrhosis, liver cancer and other life-threatening pathologies. In some clinical cases, transplantation is the only treatment to save a person's life. The department's tasks also include preparing the patient for transplantation and subsequent care in order to prevent the rejection of the transplanted organ. The department's specialists have already performed more than 2,868 successful kidney transplantations, as well as 598 liver transplantations. The surgeons have colossal clinical experience and professional skills, due to which they perform organ transplant surgery of any degree of complexity with excellent results.The department is headed by Prof. Dr. med. Ahmet Serdar Karaca.
The department's doctors specialize in performing kidney transplantation for patients with end-stage kidney disease. This disease can affect people of all age groups, including children, so the department also treats young patients with end-stage kidney diseases. Transplantation is the only life-saving treatment for a patient with this diagnosis. The department performs transplantations from living donors. Preference is given to the transplantation from related donors – parents, brothers, sisters, etc. However, if the donor material is compatible, the doctors can also perform kidney transplantation from unrelated donors. The mandatory diagnostic tests for assessing the compatibility of recipient and donor tissues are blood group determination and HLA typing. If these indicators are satisfactory, the department's specialists carefully study the donor's anamnesis and carry out comprehensive diagnostics to assess a person's health in order to exclude any risks to his body. It is obvious that the recipient also undergoes a number of mandatory diagnostic tests, including complete blood count, studies to assess the function of the liver, kidneys, endocrine system, electrocardiography, echocardiography, chest X-ray, ultrasound scanning of the abdominal organs, etc.
A kidney transplant is performed under general anesthesia. The first stage of the intervention is donor organ harvesting, which is carried out using sparing laparoscopic techniques. Due to the minimal invasiveness of the intervention, the postoperative recovery of the donor takes place in the shortest possible time, and soon he can return to his daily life. This is followed by the main stage of the operation – the transfer of the previously prepared donor material to the recipient area. After successful transplantation, the main task of the doctors is to prevent rejection of the transplanted organ. To do this, the patient must follow all the recommendations of doctors, keep a diet and take the prescribed complex of drugs, including immunosuppressants. The average duration of the donor kidney functioning is 10-15 years. After this period, the patient will need to undergo dialysis procedures or repeat kidney transplantation.
Liver transplantation is another important focus of the department's clinical practice. The operation is one of the most complicated interventions in transplant medicine and it can be performed only when the destruction of the organ becomes incompatible with human life. The main indications for liver transplantation include decompensated cirrhosis, acute liver failure, viral hepatitis B and C, Wilson's disease, liver cancer, congenital malformations of the liver and bile ducts, liver injury with crushing of its tissues and other severe pathologies. As in the case of kidney transplantation, the decision to perform an operation is made only after comprehensive diagnostics. Prior to the operation, the patient needs to undergo such diagnostic tests as liver biopsy, ultrasound and MRI scanning of the abdominal organs, Doppler ultrasound of the liver tissues and vessels, electrocardiography and echocardiography, various blood tests, including tests for the compatibility of the patient's body and the donor's liver.
In most cases, the department's surgeons perform an orthotopic liver transplantation, which involves the transplantation of the entire organ or its part to an anatomical site. In the case of a heterotopic liver transplantation, the recipient's own organ is not removed, but the donor liver is replaced by the spleen or kidney. The duration of the operation is 6-12 hours. After the operation, the patient is transferred to the intensive care unit, where he stays for 1-2 days. The average hospital stay after liver transplantation for the recipient is about 15 days. All this time, the doctors monitor the patient and take all the necessary therapeutic measures to prevent rejection of the transplanted organ. The patient will have the need for lifelong use of immunosuppressants to suppress the activity of the immune system in order to prevent rejection of the new liver.
The department's range of medical services includes:
- Kidney transplantation
- Preparation for kidney transplantation
- Living donor kidney transplantation, including laparoscopic surgery for donor material harvesting
- Kidney transplantation in children
- Follow-up care after kidney transplantation
- Liver transplantation
- Preparation for liver transplantation
- Liver transplantation
- Orthotopic liver transplantation
- Heterotopic liver transplantation
- Follow-up care after liver transplantation
- Other therapeutic options
Curriculum vitae
Higher Education and Postgraduate Training
- 1996 Master's Degree, Faculty of Medicine, Ankara University.
- 2002 Doctorate in Medicine, Faculty of Medicine, Ankara University.
- 2009 Assistant Professor, Department of General Surgery, Rize University.
- 2014 Associate Professor, Department of General Surgery, Numune Teaching and Research Hospital, Ankara.
Professional Career
- 2002 - 2006 Surgeon, Department of General Surgery, State Hospital in Bartin.
- 2006 - 2008 Surgeon, Department of General Surgery, Ataturk Training and Research Hospital in Ankara.
- 2009 - 2010 Assistant Professor, Department of General Surgery (specialization in liver and kidney transplantation), Faculty of Medicine, Ankara University.
- 2010 - 2013 Surgeon, Deputy Head of the Turkish Public Health Agency, Ministry of Health of the Republic of Turkey.
- 2013 - 2014 Surgeon, Department of General Surgery, Numune Teaching and Research Hospital, Ankara.
- 2014 - 2017 Associate Professor, Course Lecturer in Liver and Bile Duct Surgery, Department of General Surgery, Numune Teaching and Research Hospital, Ankara.
- 2017 - 2020 Associate Professor, Department of General Surgery, Faculty of Medicine, Bashkent University.
- Since 2020 Professor, Department of General Surgery, Faculty of Medicine, Bashkent University.
Awards and Honors
- 2014 Best Article Award, Journal of Clinical and Analytical Medicine (JCAM).
- Award for the First Use of a Trocar in a Laparoscopic Cholecystectomy.
Memberships in Professional Societies
- Turkish Surgical Association.
- Ankara Surgical Association.
- Turkish Association of Vascular Surgery.
- Turkish Society of Colon and Rectal Surgery.
- Turkish Association of Clinical Enteral and Parenteral Nutrition.
- Turkish Association for Endoscopic and Laparoscopic Surgery.
- Turkish Association of Trauma and Emergency Surgery.
- Turkish Society of Hepato-Pancreato-Biliary Surgery.
- European Society of Coloproctology.
Photo of the doctor: (c) Istanbul Başkent Hospital
About hospital
The Baskent University Hospital Istanbul is a progressive medical complex, whose primary purpose is to provide medical care of the highest quality in a pleasant and comfortable environment. The hospital is part of the prestigious Turkish Baskent University Healthcare Group, whose outstanding achievements are known not only nationally, but also in the international medical arena. The medical group was founded by Prof. Dr. med. Mehmet Haberal, who was the first specialist in Turkey who performed kidney transplantation from a living donor. The hospital in Istanbul opened its doors to the first patient on February 23, 2007, and since then has gained a solid reputation among the top medical facilities in Turkey.
The medical complex has a high-tech base both for accurate diagnostics and effective treatment according to international standards. Special attention should be given to the medical staff of the hospital. The hospital employs professors and doctors with colossal clinical experience. They successfully cope even with especially complex clinical cases. Many specialists underwent training in leading medical centers in America and Europe.
The hospital represents almost all branches of modern medicine. The areas of special competence of the hospital are transplant surgery, cardiac surgery, general surgery, urology, otolaryngology and other medical disciplines. The medical complex has the prestigious ISO 9001:2015 certificate, which is awarded only to the hospitals with impeccable quality of medical service.
The hospital has 125 beds for patient hospitalization, including additional beds in Intensive Care Units, Dialysis and Palliative Care Sections. Every year, the hospital admits more than 7,000 inpatients and more than 180,000 outpatients. In addition, the doctors annually perform more than 4,000 surgical interventions of varying degrees of severity in state-of-the-art operating rooms of the hospital. The medical facility admits many patients from foreign countries, which confirms its high credibility at the international level.
Photo: (c) Istanbul Başkent Hospital, (с) depositphotos
Accommodation in hospital
Patients rooms
The patients of the Baskent University Hospital Istanbul live in comfortable rooms with modern design. All patient rooms are made in light colors and have an ensuite bathroom with shower and toilet. The standard patient room furnishings include an automatically adjustable bed, a bedside table, a wardrobe for clothes, a table and chairs for receiving visitors, as well as a telephone and a TV.
Meals and Menus
The patient and the accompanying person are offered a daily choice of three menus. If you are on a specific diet for any reason, you will be offered an individual menu. Please inform the medical staff about your dietary preferences prior to the treatment.
Further details
Standard rooms include:
Toilet
Shower
Wi-Fi
TV
Accompanying person
During the inpatient program, an accompanying person may stay with the patient in the room or at a hotel. Our managers will help you choose the most suitable option.
Hotel
During the outpatient program, the patient may stay at the hotel. Our managers will help you choose the most suitable option.