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Allogeneic bone marrow transplantation in acute lymphoblastic leukemia (549099) | Gaziosmanpasa Hospital of Yeniyuzyil University - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align: justify;\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align: justify;\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.<\/p>\n\n<p style=\"text-align: justify;\">When your complete blood count returns to normal, your doctor will schedule your <strong>discharge from the department<\/strong>. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li>Medical records<\/li>\n\t<li>MRI\/CT scan (not older than 3 months)<\/li>\n\t<li>Bone marrow biopsy results (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>case history collection<\/li>\n\t<li>general clinical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>differential blood count<\/li>\n\t\t<li>inflammation indicators (CRP, ESR)<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>CT\/MRI scans&nbsp;of the whole body<\/li>\n\t<li>needle biopsy of the bone marrow with histological:\n\t<ul>\n\t\t<li>cytochemistry<\/li>\n\t\t<li>immunocytology<\/li>\n\t\t<li>cytogenetics (Philadelphia<br \/>\n\t\tchromosome detection)<\/li>\n\t\t<li>molecular biology<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>biopsy and histological examination of&nbsp;CSF<\/li>\n\t<li>examination by&nbsp;experts of:\n\t<ul>\n\t\t<li>cardiology<\/li>\n\t\t<li>otolaryngology<\/li>\n\t\t<li>immunology<\/li>\n\t\t<li>ophthalmology<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>registration in the European bone marrow donor base<\/li>\n\t<li>conducting high-dose chemotherapy<\/li>\n\t<li>allogeneic bone marrow transplantation from<br \/>\n\tunrelated donor<\/li>\n\t<li>the cost of blood products<\/li>\n\t<li>isolation by neutropenic precautions<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>control examinations<\/li>\n\t<li>the cost of essential medicines and materials<\/li>\n\t<li>nursing services<\/li>\n\t<li>full hospital accommodation<\/li>\n\t<li>explanation of future recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\"><strong>During the first visit<\/strong>, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. 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Allogeneic bone marrow transplantation in acute lymphoblastic leukemia in Gaziosmanpasa Hospital of Yeniyuzyil University

Gaziosmanpasa Hospital of Yeniyuzyil University

Istanbul, Turkey
Program id # 549099
Doctor photo
Dr. med. Serkan Güvenç
Department of Hematology and Bone Marrow Transplantation
Specialized in: hematology, bone marrow transplantation

The program includes:

  • Initial presentation in the clinic
  • case history collection
  • general clinical examination
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • differential blood count
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • CT/MRI scans of the whole body
  • needle biopsy of the bone marrow with histological:
    • cytochemistry
    • immunocytology
    • cytogenetics (Philadelphia
      chromosome detection)
    • molecular biology
  • biopsy and histological examination of CSF
  • examination by experts of:
    • cardiology
    • otolaryngology
    • immunology
    • ophthalmology
  • registration in the European bone marrow donor base
  • conducting high-dose chemotherapy
  • allogeneic bone marrow transplantation from
    unrelated donor
  • the cost of blood products
  • isolation by neutropenic precautions
  • symptomatic treatment
  • control examinations
  • the cost of essential medicines and materials
  • nursing services
  • full hospital accommodation
  • explanation of future recommendations

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.

Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.

Before the procedure, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.

The bone marrow transplant procedure is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.

During the period of healthy bone marrow engraftment, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.

A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.

When your complete blood count returns to normal, your doctor will schedule your discharge from the department. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Bone marrow biopsy results (if available)

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About the department

The Department of Hematology and Bone Marrow Transplantation at the Gaziosmanpasa Hospital of Yeniyuzyil University offers the full range of services in these field. The department has 15 beds. It is one of the largest and most reputable medical facilities, which specializes in allogeneic and autologous bone marrow transplantation. The highly qualified, experienced doctors and attentive nursing staff take care of the patient health. The department is headed by Dr. med. Serkan Güvenç.

Each room is equipped with a state-of-art monitoring system, which allows the doctor to monitor the condition of patients round-the-clock. Also, all rooms are equipped with the necessary equipment for intensive care. A feature of the department is the air purification system, which includes HEPA fans and the CFD air flow simulation technique. Thus, the department has a hybrid type of air flow, which provides the protection against airborne infections.

The department specializes in the following types of bone marrow transplantation:

  • Allogeneic bone marrow transplantation is performed using cells from a healthy donor (related or unrelated). Before the transplantation, it is necessary to carry out the procedure of conditioning. It usually involves the administration of high doses of chemotherapy in combination with radiation therapy or without it. This is a prerequisite for the treatment of progressive disease, as well as for the suppression of the patient’s immune system and prevention of the donor cell rejection. After the transplantation, the patient requires hospitalization in special conditions (usually from 2 to 4 weeks).
  • Autologous bone marrow transplantation is a transplantation of the patient’s own stem cells. The patient’s presampled and frozen healthy bone marrow stem cells are administered to him after the high-dose chemotherapy. This allows to restore the patient’s immune and hematopoietic systems in a short period of time. However, this type of bone marrow transplantation is recommended if the disease is in remission or when the disease does not affect the bone marrow. If the tumor process has affected the bone marrow, autologous transplantation is contraindicated.

The service range of the department includes the diagnostics and treatment of the following diseases:

  • Thalassemia
  • Sickle cell anemia
  • Aplastic anemia
  • Myelodysplastic syndrome
  • Acute and chronic lymphocytic leukemia
  • Acute and chronic myeloid leukemia
  • Hodgkin's disease
  • Non-Hodgkin's lymphomas
  • Multiple myeloma
  • Blood clotting disorders (including thrombocytopathy and coagulation factor deficiency)
  • Solid tumors
  • Hereditary diseases of the hematopoietic system
  • Myeloproliferative diseases
  • Immunodeficiency
  • Other diseases and pathological conditions

Photo of the doctor: (c) Private Gaziosmanpasa Hospital 


About hospital

The Gaziosmanpasa Hospital of Yeniyuzyil University is a private maximum care medical facility with the high standards of patient care. The hospital began its activities in 1992 and during this time has gained an excellent reputation in Turkey and in many other countries of the world.

The hospital building covers an area of ​​60,000 square meters and is designed to accept 350 inpatients. The construction of the hospital was designed using modern earthquake-resistant technology and carried out in accordance with the international requirements. The facility has 12 high-tech operating rooms with the advanced surgical and navigation systems, for example, DaVinci surgical system, Gamma Knife, etc. During the long years of productive work, the hospital has performed more than 60,000 successful operations and delivered more than 22,000 babies. It should be noted that the medical facility is especially focused on transplantology, surgery, cardiology, oncology, and reproductive medicine. Also, plastic surgery and hair transplantation are very popular.

In 2007, the hospital standardized the quality of medical services and received the prestigious ISO 9001: 2008 certificate. In addition, in 2009, the hospital was awarded Class A status, which means the highest level of medical care, and it maintains this title every year. Since March 2013, the medical facility has initiated a process for obtaining an internationally recognized and world-famous accreditation assessment model from Joint Commission International (JCI).

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Gaziosmanpasa Hospital of Yeniyuzyil University live in comfortable rooms of a five-star hotel level. The rooms are designed in beige and brown colors and they are equipped with all the necessary facilities, such as an automatically adjustable bed, a wardrobe and a bedside table for personal belongings, a small couch and armchairs for visitors, a TV and a telephone. Also, each room has an ensuite bathroom with shower and toilet.

Meals and Menus

The patients of the hospital are offered tasty and balanced three meals a day: buffet breakfast, lunch and dinner. Also, with appropriate clinical indications or if desired, a diet menu is provided.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV