Chemotherapy and radiation therapy for Ewing sarcoma (program ID: 597008)
Helios Hospital Berlin-Buch
Robert KrempienSpecialized in: adult and pediatric radiation therapy, radiation oncology
Department of Adult and Pediatric Radiation Therapy, Radiation Oncology
- Initial presentation in the clinic
- clinical history taking
- review of medical records
- physical examination
- laboratory tests:
- complete blood count
- general urine analysis
- biochemical analysis of blood
- TSH-basal, fT3, fT4
- tumor markers
- inflammation indicators (CRP, ESR)
- indicators blood coagulation
- full course of the chemotherapy and radiation therapy
- nursing services
- consultation of related specialists
- explanation of individual treatment plan
- Medical records
- MRI/CT scan (not older than 3 months)
- Biopsy results (if available)
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About the department
The Department of Adult and Pediatric Radiation Therapy, Radiation Oncology at the Helios Hospital Berlin-Buch specializes in all types of modern radiation therapy for the treatment of cancers and pain syndromes. Radiation therapy can be performed before, during or after surgery. In some cases, the department's doctors manage to achieve a positive result only with the help of radiation therapy, and thereby eliminate the need for surgical treatment. Prior to radiation therapy, it is carefully planned using the very latest imaging systems. The department's doctors are highly professional experts and have unique experience, thanks to which they provide excellent medical services. The Chief Physician of the department is Prof. Dr. med. Robert Krempien.
Thanks to the available innovative computer technologies, the department's doctors have the opportunity to carefully examine the patient prior to radiation therapy and determine the necessary radiation dose as accurately as possible in order to achieve an effective result. At the same time, the department's specialists apply irradiation techniques to maximize the impact on the tissues affected by pathology, but not to impact on the healthy ones.
It is worth noting that the department is one of four medical facilities in Germany, which provides intraoperative electron radiation therapy. To carry out this type of therapy, the doctors apply an ultramodern mobile linear accelerator, which is the source of electronic radiation. Currently, this technique is considered the fastest, safest, most versatile and accurate option for intraoperative radiation therapy. During the therapy, the accelerator generates a high-dose electron beam, which is directed to the tumor, while classical radiation therapy involves irradiation from the outside, through the skin and healthy tissues. The electrons pass through a manipulator, on which a linear accelerator is mounted. During the procedure, the surgeon and radiation therapist work hand in hand. The exposure time during the surgery lasts no more than 1-2 minutes.
To treat superficial tumors, in particular, skin tumors, the department's doctors mostly use X-ray irradiation. Such irradiation is suitable for the treatment of both skin malignancies, and benign skin changes (for example, keloid scars). The therapy can be applied if the tumor cannot be removed surgically due to its size or location, or as an additional treatment after surgery (especially after surgical removal of basal and squamous cell carcinoma).
The department also provides radiation therapy for the treatment of degenerative and inflammatory joint diseases. In this case, X-ray irradiation (orthovoltage x-ray therapy) is applied. The therapy is particularly effective in patients with acute and chronic joint diseases, arthrosis, arthritis, pain syndromes, tendon lesions, Dupuytren's contracture and Ledderhose disease.
The therapeutic options of the department include the treatment of the following diseases:
- Uterine and cervical cancer
- Lung cancer
- Benign and malignant brain tumors (for example, astrocytomas, glioblastomas and meningiomas, as well as brain metastasis)
- Malignant neoplasms in children
- Genitourinary cancer in men (prostate cancer, bladder cancer)
- Head and neck tumors
- Gastrointestinal tumors
- Benign joint diseases
- Other pathologies
The department specializes in the following types of radiation therapy:
- Intraoperative electron radiation therapy
- X-ray exposure for superficial benign and malignant skin neoplasms
- Pain therapy using irradiation for degenerative and inflammatory joint diseases
- Preoperative radiation therapy
- Radiation therapy in combination with immunotherapy
- Psycho-oncological care
- Other types of radiation therapy
Education and Professional Сareer
- 1992 Faculty of Medicine, University of Heidelberg; Research Fellow at the Mount Sinai Medical Center in Toronto (Canada); Clinical Officer, Faculty of Medicine, Wuhan University (People's Republic of China) and Frenchay Hospital (England).
- 1993 Residency in the Department of Internal Medicine at the University Hospital Heidelberg.
- 1995 Work in the Department of Radiation Oncology at the University Hospital Heidelberg and at the German Cancer Research Center.
- 2001 Board certification in Radiation Oncology
- 2002 - 2007 Work in the Department of Radiation Oncology and the Department of Brachytherapy at the University Hospital Heidelberg.
- 2003 Head of the Department of Intraoperative Radiation Therapy.
- 2004 Assistant Professor at the University of Heidelberg.
- 2006 Professorship.
- 2003 - 2007 Work at the National Cancer Center of the University of Heidelberg and the German Cancer Research Center.
- 2007 Head of the Department of Adult and Pediatric Radiation Therapy, Radiation Oncology at the Helios Hospital Berlin-Buch.
Prizes and Honors
- 2001 Jean Paul Obrecht Award.
- 2003 Prize for Technical Innovation in Radiation Oncology at the Meeting of the German Society of Radiation Oncology (DEGRO).
Special Clinical Focuses
- Breast cancer treatment.
- Prostate cancer treatment.
- Radiation therapy for the treatment of benign, degenerative and inflammatory diseases, as well as endocrine ophthalmopathy.
Photo of the doctor: (c) Helios Klinikum Berlin-Buch