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In vitro fertilization (IVF) short protocol (617068) | Memorial Sisli Hospital Istanbul - BookingHealth
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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician&nbsp;for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><strong>The type of protocol (the long or short one) is selected by the physician.<\/strong><\/p>\n\n<p style=\"text-align: justify;\"><strong><u>Service support<\/u><\/strong><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. We provide you with an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, translating medical reports.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Results of hormone blood tests (if available)<\/li>\n\t<li style=\"text-align: justify;\">Pelvic ultrasoud (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li style=\"text-align:justify\">Initial presentation in the clinic<\/li>\n\t<li style=\"text-align:justify\">Case history taking<\/li>\n\t<li style=\"text-align:justify\">Review of medical records<\/li>\n\t<li style=\"text-align:justify\">General physical examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Laboratory tests:&nbsp;<\/strong>\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Complete blood count&nbsp;<\/li>\n\t\t<li>General urine test<\/li>\n\t\t<li>Biochemical blood test<\/li>\n\t\t<li>Inflammation markers<\/li>\n\t\t<li>Blood coagulation test&nbsp;<\/li>\n\t\t<li>Immune status<\/li>\n\t\t<li>Hormone levels:\n\t\t<ul>\n\t\t\t<li>FSH<\/li>\n\t\t\t<li>LH<\/li>\n\t\t\t<li>Androgens<\/li>\n\t\t\t<li>Progesterone<\/li>\n\t\t\t<li>Prolactin<\/li>\n\t\t\t<li>TSH-basal, fT3, fT4&nbsp;<\/li>\n\t\t<\/ul>\n\t\t<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Ultrasound examination of abdomen and small pelvis organs&nbsp;<\/li>\n\t<li style=\"text-align:justify\">Transvaginal ultrasound scan<\/li>\n\t<li style=\"text-align:justify\">Gynecological examination<\/li>\n\t<li style=\"text-align:justify\">Colposcopy<\/li>\n\t<li style=\"text-align:justify\">Hormonal stimulation&nbsp;<\/li>\n\t<li style=\"text-align:justify\"><strong>In vitro fertilization (IVF)<\/strong><\/li>\n\t<li style=\"text-align:justify\">Nursing services<\/li>\n\t<li style=\"text-align:justify\">Consultations of related specialists<\/li>\n\t<li style=\"text-align:justify\">Treatment by head doctor and all leading experts<\/li>\n\t<li style=\"text-align:justify\">Explanation of the individual treatment plan<\/li>\n<\/ul>\n\n<p style=\"text-align:justify\"><em>All aspects of the program can be discussed with a medical advisor.<\/em><\/p>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\">You <strong>arrive in the hospital<\/strong> on the first day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician&nbsp;for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. 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In vitro fertilization (IVF) short protocol in Memorial Sisli Hospital Istanbul

Memorial Sisli Hospital Istanbul

Istanbul, Turkey
Program id # 617068
Doctor photo
Prof. Dr. med. Semra Kahraman
Department of Reproductive Medicine
Specialized in: reproductive medicine
Specialization Curriculum vitae

The program includes:

  • Initial presentation in the clinic
  • Case history taking
  • Review of medical records
  • General physical examination
  • Laboratory tests: 
    • Complete blood count 
    • General urine test
    • Biochemical blood test
    • Inflammation markers
    • Blood coagulation test 
    • Immune status
    • Hormone levels:
      • FSH
      • LH
      • Androgens
      • Progesterone
      • Prolactin
      • TSH-basal, fT3, fT4 
  • Ultrasound examination of abdomen and small pelvis organs 
  • Transvaginal ultrasound scan
  • Gynecological examination
  • Colposcopy
  • Hormonal stimulation 
  • In vitro fertilization (IVF)
  • Nursing services
  • Consultations of related specialists
  • Treatment by head doctor and all leading experts
  • Explanation of the individual treatment plan

All aspects of the program can be discussed with a medical advisor.

How program is carried out

You arrive in the hospital on the first day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.

The reproductologist will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician for advice at any time.

For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).

Stages of treatment

Ovarian stimulation. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.

The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).

Egg collection. In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men – the ICSI procedure).

Fertilization. 2-6 hours after egg collection, eggs are fertilized with the husband’s sperm. This is a laboratory procedure and no patient involvement is required.

Embryo culture. Fertilized eggs will be cultured for 1-5 days. According to patients’ needs and embryo status, best 1-3 embryos can be transferred to the womb.

Preimplantation genetic diagnosis. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.

Embryo transfer. This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.

Pregnancy test. This test can be done 14 days after the embryo transfer.

The type of protocol (the long or short one) is selected by the physician.

Service support

We fully support your trip, regardless of the chosen program. We provide you with an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, translating medical reports.

Required documents

  • Medical records
  • Results of hormone blood tests (if available)
  • Pelvic ultrasoud (if available)

Service

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About the department

The Department of Reproductive Medicine at the Memorial Sisli Hospital Istanbul offers the full range of top-class medical services for patients with fertility disorders. The primary specialization of the medical facility is in vitro fertilization, which helps women to achieve the desired pregnancy. 

The Chief Physician of the department is Prof. Dr. med. Semra Kahraman. The specialist is an internationally recognized doctor in his field of competence. She is engaged not only in clinical, but also in research activities, implements innovative approaches to the treatment of infertility in the department, thanks to which she achieves excellent results.

As of today, the department has earned an impeccable reputation not only in Turkey but throughout the world. The department pioneered the use of such techniques as surgical sperm retrieval and microinjection, embryo freezing procedures, endometrial cell cultivation and preimplantation genetic diagnostics in Turkey. Thanks to the professional treatment of infertility, more than 10,000 babies were born within the walls of the hospital.

Structurally, the department consists of the In Vitro Fertilization Center, the Andrology Center and the Perinatal Center, as well as various specialized laboratories. It is the only hospital of this kind in Turkey, which combines all related disciplines under one roof. In addition, the department is the first and only center, which is certified by the Ministry of Health to train doctors, embryologists, biologists and nurses for in vitro fertilization (IVF) procedures.

The department also specializes in preimplantation genetic diagnostics of embryos in couples with the risk of genetic pathologies. This type of diagnostics can reveal thalassemia, spinal muscular atrophy, hemophilia and other pathologies in the embryo.

The department's medical team, which consists of 70 highly qualified specialists applies all their experience and clinical knowledge in order to bring the woman the long-awaited joy of motherhood. The use of the latest and the most effective treatment methods contributes to the fact that excellent results are achieved here. The best proof of the impeccable medical service is the steadily growing number of patients who come here from different parts of the world.

The department's range of medical services includes:

  • Clinical procedures
    • Diagnostics of infertility in men and women
    • Infertility treatment using classic and innovative techniques – ovulation induction, intrauterine insemination, in vitro fertilization
    • Oocyte retrieval using transvaginal ultrasound
  • Surgical procedures for the diagnostics and treatment of infertility
    • Hysteroscopy (method of minimally invasive examination of the uterine cavity using hysteroscope with the possibility of therapeutic manipulations)
    • Laparoscopy (minimally invasive surgical technique for the examination of the abdominal organs, ovaries, uterus, and fallopian tubes)
  • Procedures for the diagnostics and treatment of male infertility
    • Spermogram
    • Sperm FISH analysis in severe types of male infertility
    • Extended diagnostics of male infertility – Halo, Tunnel tests, etc.
    • Cryopreservation of testicular and sperm tissues
    • Microdissection testicular sperm extraction (micro-TESE)
    • Testicular sperm aspiration (TESA)
  • Innovative procedures
    • Co-cultivation of embryo with endometrium
    • Preimplantation genetic diagnosis (PGD)
    • Oocyte maturation in the laboratory
    • HLA typing for the determination of the biological compatibility of cells, which are participants of the In Vitro Fertilization Program
    • Rapid freezing of spermatozoa, embryos and ovarian tissue by means of vitrification
    • Immunoglobulin therapy
  • Genetic health services
    • Genetic consultations for couples who already have a child with a genetic disorder or for couples who are carriers of a genetic disorder
    • Analysis of chromosome structure and quantity (karyotype analysis)
    • Preimplantation genetic diagnostics for the exclusion of chromosomal abnormalities in the embryo before transfer to the uterus
    • HLA typing for diseases caused by such genetic defects as thalassemia, leukemia, etc.
    • Cytogenetic testing after amniocentesis, cordocentesis
    • QF-PCR amniocentesis 
    • Diagnostics of such life-threatening diseases as Mediterranean anemia, cystic fibrosis, sickle cell anemia in embryos
  • Other diagnostic and therapeutic options

Curriculum vitae

Professional Career

  • Since 2000 Head of the Department of Reproductive Medicine at the Memorial Sisli Hospital Istanbul.
  • 1996 - 1997 Work at the Institute of Reproductive Genetics, Chicago, USA.
  • 1996 - 1997 Work at the Weill Cornell's Center for Reproductive Medicine, New York, USA.
  • 1996 - 1997 Schoysman Infertility Management Foundation (SIMAF), Van Helmont Hospital, Vilvoorde, Belgium.
  • 1993 - 2000 Head of the Center for Reproductive Medicine, Sevgi Hospital, Ankara, Turkey.
  • 1991 - 1992 Work at the Fertility Center, Oslo University Hospital, Norway.

Higher Education and Postgraduate Training

  • 2004 Professorship, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.
  • 1994 Assistant Professorship, Faculty of Medicine, Ankara University, Ankara, Turkey.
  • 1983 - 1989 Professional training in Gynecology and Obstetrics, Faculty of Medicine, Ankara University, Ankara, Turkey.
  • 1973 - 1981 Study of Human Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Awards and Honors

  • 2018 and 2017 American Society for Reproductive Medicine (ASRM) Star Awards.
  • 2015 Medical Travel Journal Awards – Department of Reproductive Medicine at the Memorial Sisli Hospital Istanbul is recognized as the International Hospital of the Year in the field of its specialization, London, UK.
  • 2014 Grant for Innovations in Fertility Treatment, Project "Detection of markers of oocyte competence using maturation analysis" – one of the best projects in the field of fertility research, Munich, Germany.
  • 2013 Award for Scientific Contribution in Reproductive Medicine, Ankara, Turkey.
  • 2008 Lifetime Achievement Award, Turkish Society for Reproductive Medicine (TSRM).
  • 2004 Award for the Best Researcher of the Year (Human Embryonic Stem Cell Research), TEMPO Journal.
  • 2001 Best Presentation Award.
  • 1997 and 1996 TUBİTAK Honorable Award.
  • 1996 Poster Award.

Memberships in Professional Societies

  • 2013 - 2015 President of the Preimplantation Genetic Diagnosis International Society (PGDIS).
  • Board Member of the Preimplantation Genetic Diagnosis International Society (PGDIS).
  • Member of the European Society of Human Reproduction and Embryology (ESHRE).
  • Member of the American Society for Reproductive Medicine (ASRM).
  • Jury Member on Awarding of the Royan Institute.
  • Member of the Turkish Society for Reproductive Medicine (TSRM).
  • Member of the Turkish Society of Obstetrics and Gynecology (TJOD).
  • Association for Reproductive Medicine (ÜTD).

Photo of the doctor: (c) Memorial Şişli Hospital 

About hospital

The Memorial Sisli Hospital Istanbul is the largest and leading medical complex in Turkey, which meets the highest standards of medical care when providing the advanced diagnostics and treatment using the very latest methods. The hospital is part of the Memorial Health Group – it was the first project of this provider of medical services. The medical center opened its doors to the first patient in 2000. The hospital became the first in Turkey and the twenty-first in the world holder of the JCI (Joint Commission International) accreditation certificate. Only the best and the most reputable hospitals in the world medical arena can receive this certificate.

The hospital has 292 beds for patient hospitalization. The surgical treatment is performed in 13 high-tech operating rooms. The medical complex also has 4 intensive care units, 3 state-of-the-art laboratories, specialized centers, including the In Vitro Fertilization Center, the Transplant Center, the Center for Genetic Diseases, the Bone Marrow Transplant Center, the Robotic Surgery Center, the Cancer Center and others.

The hospital has achieved particular success and international recognition in such medical fields as ophthalmology, reproductive medicine, plastic surgery, cardiology and cardiac surgery, transplantology, genetics. The highly qualified doctors who have undergone professional training in the best hospitals in Turkey, Europe and the USA take care of the patients' health. The specialists have a tremendous clinical experience and thousands of saved lives.

It is worth noting that the medical complex has earned a strong reputation not only in Turkey, but also at the international level – the hospital holds consultations, provides diagnostics and treatment for patients from 92 countries.

Image: (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Memorial Sisli Hospital Istanbul live in comfortable single or double rooms with all the necessary amenities. The patient rooms are made in a modern design. The standard patient room includes an automatically adjustable bed, a bedside table, a wardrobe for storing personal belongings, a telephone and a TV. Each patient room also has an ensuite bathroom with shower and toilet. The patient rooms have Wi-Fi.

Meals and Menus

The patient and the accompanying person are offered tasty and balanced three meals a day. If for some reason you do not eat all foods, you will be offered an individual menu. Please inform the medical staff about your food preferences prior to treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Accompanying person

During the inpatient program, the accompanying person can live with the patient in a patient room or a hotel of his choice. Our managers will help you choose the most suitable option.

Hotel

During an outpatient program, the patient can stay at the hotel of his choice. If desired, the patient can stay in a five-star hotel on the territory of the hospital. Our managers will help you choose the most suitable option.