google_counter
background_img

Acute Myeloid Leukemia (AML): Diagnostic in the Best Hospitals in the World

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of services in these medical fields. It diagnoses and treats all benign and malignant blood diseases, cancers. The huge clinical experience and high competence of the doctors working in the department allow them to achieve excellent treatment results even in the most severe cases.

Include:
people Interpreter up to 12 hours
list Translation up to 10 pages
card_membership Visa support
book Insurance against increased costs in case of complications with a cover of 200,000 €

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology offers the full range of services in these fields. It provides the accurate diagnostics and effective treatment of oncological diseases, benign and malignant blood pathologies, rheumatic and infectious diseases. A separate focus of the department is palliative care aimed at relieving pain and improving the quality of life of the terminally ill patients. The doctors of the department have unique clinical skills and rich experience, which contributes to high treatment success rates.

Medicana International Ankara Hospital

9/10
location_onTurkey, Ankara

Department of Hematology and Bone Marrow Transplantation

The Department of Hematology and Bone Marrow Transplantation at the Medicana International Ankara Hospital is a leading private medical center in Ankara offering services of bone marrow transplantation. In the nine-bed Department, various kinds of bone marrow transplantation are performed to treat a wide range of both oncohematological and other diseases. Since December 2012, the Department is licensed by the Ministry of Health in Turkey.

Samsung Medical Center Seoul

9.8/10
location_onSouth Korea, Seoul

Department of Oncology and Hematology

The Department of Oncology and Hematology offers the full range of services in these medical fields. The main clinical focuses include diagnostics and treatment of various forms of oncological diseases and blood diseases. The medical team of the department strives not only to prolong the life of patients, but also to improve its quality.

 

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Hematology

The Department of Hematology provides highly qualified care to patients suffering from various blood diseases, including malignant hematological diseases. The treatment of malignant diseases of the hematopoietic system is based on the use of various schemes of intensive chemotherapy and bone marrow transplantation. If desired, the patients can be treated within the clinical trials. As a rule, this option is offered to the patients who do not have positive dynamics due to the application of classical treatment methods.

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of blood diseases, coagulation disorders, oncological diseases and related pathological conditions. The treatment is provided both on an outpatient and inpatient basis. The patient is offered a comprehensive treatment, including intensive care to eliminate side effects associated with the tumor and therapy, development of individual recommendations on nutrition, physiotherapeutic measures and psycho-oncological care.

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

The Department of Hematology, Oncology, Adult and Pediatric Rheumatology offers the full range of modern diagnostics and treatment of malignant diseases, rheumatic pathologies, including particularly complex clinical cases in these fields. In addition, the department's doctors specialize in stem cell transplantation and occupy leading positions in this field at the international level. The medical team of the department makes every effort to guarantee each patient an individual, first-class treatment, based on the very latest achievements of modern medicine and human respect, understanding of the needs of each patient.

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectology offers the full range of medical services in the fields of its specialization. The department specializes in the diagnostics and treatment of all diseases of the hematopoietic system, systemic treatment of solid tumors, infectious diseases, including outpatient admission of patients with HIV, blood clotting disorders, as well as the entire clinical and morphological group of rheumatic diseases. The department is actively engaged in research activities and regularly implements the latest medical developments into clinical practice, thereby providing treatment in accordance with the most advanced scientific achievements.

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

The Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology offers the full range of diagnostics and treatment in these fields. The department specializes in the treatment of benign and malignant diseases of the digestive system, liver and bile ducts, the hematopoietic system, etc. Much attention is paid to the interdisciplinary cooperation (Cancer Center Mainfranken, etc.).

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

The Department of Oncology and Hematology offers accurate diagnostics and effective treatment of benign and malignant blood diseases, as well as solid tumors. The department's specialists are proud of the excellent results in the field of bone marrow transplantation, which is among the department’s priority focuses. The department has 61 beds. Medical care is carried out both on an outpatient and inpatient basis.

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

The Department of Hematology and Oncology offers the full range of diagnostics and treatment of diseases of the hematopoietic system, such as acute or chronic leukemia, malignant lymphomas, as well as solid malignant tumors, which require chemotherapy or other systemic therapies. The department offers all systemic treatments, including bone marrow transplantation, antibody therapy. The main goal of each medical team employee is to provide patients with a competent medical care.

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the Focus magazine, the Department of Hematology and Oncology ranks among the top German medical facilities specializing in bowel cancer treatment! The department offers the full range of specialized diagnostics, treatment and follow-up care for patients with oncological diseases and blood diseases. The department's doctors have in their arsenal many innovative effective methods to fight against cancer. In addition, a number of clinical trials are carried out here in order to develop the very latest targeted drugs, immunotherapy drugs, etc. All the department's specialists regularly undergo advanced training courses, which help them to keep abreast of innovations in medicine and to guarantee the best therapy result for patients.

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the Department of Hematology, Oncology and Pulmonology ranks among the top medical facilities in Germany specializing in bowel cancer treatment! The department offers the full range of modern diagnostics and treatment of solid tumors, benign and malignant blood and hematopoietic system diseases, including bleeding disorders, as well as pathologies of the lungs and other organs of the respiratory system. The offer is complemented by effective palliative care. All physicians of the department are highly qualified experts in their area of specialization and apply theoretical knowledge and clinical experience to ensure an optimal therapy result.

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

Charité Comprehensive Cancer Center offers patients the full range of classical and innovative examinations, treatment of malignant diseases of all organs and anatomical structures of the human body. The spectrum is complemented by follow-up medical care, rehabilitation, modern schemes for the prevention and early detection of malignant diseases. An important component of the therapeutic process in the center is psycho-oncological care. The centerdals with the treatment of patients of all age groups, ranging from small children to elderly patients.

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

The Department of Oncology, Hematology, Rheumatology and Immunoncology offers the full range of diagnostics and treatment of solid tumors, benign and malignant diseases of blood and bone marrow, rheumatic pathologies. The priority purpose of each employee in the department is to provide patients with an optimal medical care, based on the use of the very latest treatment methods. The department's specialists are distinguished by their high professionalism and colossal experience in the treatment of extremely complex clinical cases.

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

The Department of Oncology and Hematology offers the full range of services in the field of diagnostics and treatment of oncological and blood diseases. Of particular interest is the treatment of patients with acute leukemia, lymphomas, carcinomas and sarcomas. The highly qualified medical team of 65 doctors and 130 nurses takes care of the health of the patients. About 2,800 inpatients and 10,000 outpatients are treated in the department annually.

Acute myeloid leukemia is a prognostically unfavorable disease. It can develop in an adult or child, but older people are more likely to get sick. The average age of the patient is 63 years. The older the person, the higher the risk of developing pathology. The age is also an unfavorable prognostic factor that reduces the success of treatment.

Symptoms 

Acute myelogenous leukemia usually does not have specific symptoms, for which this disease could be suspected. However, the developing non-specific signs of the pathological process in the patient usually become the reason for going to the doctor. In the clinic, he will undergo blood tests, and with them the doctor can detect changes characteristic of myeloid leukemia.

The main symptoms of the disease are: 

  • Weight loss.
  • Fatigue.
  • Fever.
  • Night sweats.
  • Decreased appetite.

Due to the impaired bone marrow function, the amount of normal blood cells in the blood decreases over time: red blood cells, white blood cells and platelets. They are responsible respectively for oxygen transport, immunity and blood coagulation. Depending on which disorders prevail, additional symptoms may develop:

  • Pale skin, shortness of breath, tachycardia, dizziness, headache.
  • Frequent bacterial infections, the formation of abscesses on the skin.
  • Skin bruising, nosebleeds, bleeding gums, heavy and prolonged menstruation after puberty.

A large number of pathologically altered, too large white blood cells accumulate in the blood. They do not ensure the functioning of the immune system, but can clog important vessels. This phenomenon is called leukostasis. It develops at a blast cell concentration of 100 thousand in 1 mcl. The result may be shortness of breath, blurred vision, weakness on one side of the body, drowsiness. Such symptoms require emergency medical care. Most of them are associated with oxygen starvation of brain regions.

Other possible symptoms:

  • Bone and joint pain.
  • Abdominal swelling.
  • Development of blood clots in the veins.
  • Rash.
  • Vomiting.
  • Impaired coordination of movements.
  • Enlarged lymph nodes. 

Early diagnostics 

Although there is no screening for acute myelogenous leukemia, its symptoms manifest themselves quite early. A visit to the doctor at the first signs of a serious pathology is the best way to diagnose myeloid leukemia early. 

A periodic undergoing of a complete blood count is indicated without the occurrence of any symptoms only to patients at risk for myeloid leukemia. These include: 

  • Down syndrome.
  • Myelodysplastic syndrome.
  • Chemotherapy or radiation therapy in a medical history. 

Although in this category of patients the risk of disease is higher, most of them do not develop myeloid leukemia.

Establishment of the diagnosis 

In the diagnosis of acute myeloid leukemia, the main role is played by laboratory tests, rather than medical imaging methods, as with other malignant processes. The doctor begins by studying the medical history, conducts a physical examination of the patient. Regardless of the reason for the visit to the clinic, everyone is assigned a complete blood count at the initial appointment with the doctor. It can detect impairments. After this, a hematologist will be involved in further diagnostics.

Here are some basic procedures for confirming the diagnosis: 

  • Bone marrow aspiration.
  • Bone marrow biopsy. 

Typically, two samples can be obtained simultaneously. The biomaterial is mostly sampled from the pelvic bones, less often it can be obtained from the sternum.

Bone marrow aspiration is suction using a syringe. A biopsy is performed in the second stage. During the study, a thick needle is pressed into the bone. As a result, the doctor receives a column of the pelvic bone and bone marrow, which is subject to histological examination. The procedure can be performed both for the initial diagnostics of the disease, as well as for the further diagnostics for the assessment of the response to ongoing chemotherapy or for the identification of a relapse of the pathology.

Sometimes, liquor can be tested as well. This is rarely done, only if there are signs of damage to the central nervous system. 

Changes in the tests 

Leukemia can be detected using a routine blood test, whereas the subsequent bone marrow examination has only a clarifying value.

In myeloid leukemia, blood contains few red blood cells and platelets. There are many white blood cells, but they are inferior. These forms of white blood cells are called myeloblasts. They are immature white blood cells, and for this reason they are not able to perform the function of ensuring the normal work of the immune system.

The diagnosis is established through the red bone marrow testing. It is considered confirmed if there are more than 20% blast cells in the sample. Normally, their levels should not exceed 5%, and they should be completely absent in the blood. If blast cell levels in the red bone marrow are more than normal, but less than 20%, the diagnosis can be established using genetic testing.

Additional diagnostic methods: 

  • Cytochemical study.
  • Immunophenotyping.
  • Cytogenetic diagnostics.
  • Fluorescence hybridization. 
  • PCR. 

The clarifying tests allow the doctors to predict the further development of the disease and better plan treatment.

Although imaging methods are usually not required, some patients may undergo them. If the doctor suspects the presence of a tumor in some organ (spleen, liver, kidney, brain or lymph node), it should be detected.

The diagnostics is performed not only to establish a diagnosis, but also after treatment. The goal of therapy is to achieve remission. A complete remission is when the levels of blast cells in the bone marrow decrease to less than 5%. A molecular remission suggests the inability to detect signs of myeloid leukemia even using PCR (the most sensitive of all tests). With an increase in blast forms in the bone marrow to 5% or more, relapse is detected.

Where can you seek medical help? 

You should not necessarily undergo the diagnosis of acute myeloid leukemia in your home country. You may receive better medical care abroad. If medicine is not well developed in your home country or you have to wait for the diagnostics and treatment too long, you can go to one of the best clinics in the world.

The Booking Health company will help you organize your trip. When using our services, you will get a number of benefits: 

  • We will choose for you a modern German clinic, in which a child or an adult can undergo highly accurate diagnosis of acute myeloid leukemia. This allows you to better plan your treatment.
  • Diagnostic financial expenses will be lower up to 50% due to the lack of overpricing and additional coefficients for foreign patients.
  • Booking an appointment on the most suitable dates for you.
  • Preparation of the program taking into account previously performed diagnostic tests and instrumental diagnostics.
  • Establishment of communication with a doctor in the German clinic. 
  • Monitoring of all stages of the program. 
  • Control of invoices, return of unspent funds.
  • Buying and forwarding of medicines.
  • Organization of additional diagnostic procedures or treatment in case of relapse.
  • Communication with the clinic after the treatment of acute myeloid leukemia abroad.

The Booking Health company will provide top-class services. We will buy airline tickets for you, book a hotel, meet you at the German airport and deliver to the medical facility by car.

The cost of Acute myeloid leukemia (AML) diagnostics starts from 14481.
To apply for Acute myeloid leukemia (AML) diagnostics of you can submit your request at BookingHealth.



Feedback of our customers from other resources

Need Help?

Thank you!

We received your treatment application in the best Europe clinics. Our manager will contact you within the next 24 hours.