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Diagnostic and treatment of Acute myeloid leukemia

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Best hospitals and doctors for acute myeloid leukemia treatment abroad

The selection of doctors and clinics is carried out on the basis of annual qualification reports. The main selection criterion is the number of operations or procedures performed. It takes into account experience, reputation in the medical society, the availability of quality certificates and high specialization in a certain field.

Cost for treatment

Acute Myeloid Leukemia (AML) Diagnosis
 from  10052
Allogeneic bone marrow transplantation in acute myeloid leukemia
 from  172579
Consolidation treatment of acute myeloid leukemia
 from  41202

University Hospital Mannheim

9.8/10
location_onGermany, Mannheim

Department of Hematology and Oncology

According to the reputable Focus magazine, the University Hospital Mannheim ranks among the top medical institutions of Germany, which is an undeniable confirmation of the impeccable medical care and excellent reputation of the hospital! The hospital is a high-tech modern medical institution, which provides accurate diagnosis an
Acute Myeloid Leukemia (AML) Diagnosis
14682
Allogeneic bone marrow transplantation in acute myeloid leukemia
212489
Consolidation treatment of acute myeloid leukemia
73220

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Hematology, Oncology, Palliative Care, Rheumatology and Infectology

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Acute Myeloid Leukemia (AML) Diagnosis
16304
Allogeneic bone marrow transplantation in acute myeloid leukemia
271768
Consolidation treatment of acute myeloid leukemia
71970

Medicana International Ankara Hospital

9/10
location_onTurkey, Ankara

Department of Hematology and Bone Marrow Transplantation

The Medicana International Ankara Hospital is one of the leading medical centers, which belongs to the largest medical network Medicana in Turkey. The hospital incorporates all specialties of the modern medicine under one roof. It particularly focuses on bone marrow transplantation, cardiology, cardiovascular surg
Acute Myeloid Leukemia (AML) Diagnosis
12120
Allogeneic bone marrow transplantation in acute myeloid leukemia
173100
Consolidation treatment of acute myeloid leukemia
49934

Samsung Medical Center Seoul

9.8/10
location_onSouth Korea, Seoul

Department of Oncology and Hematology

The Samsung Medical Center was founded in 1994 and soon won the reputation of a medical facility of presidential standards, which it still preserves today. The hospital has 40 departments, 10 specialized centers and a huge Cancer Center with 655 beds. The medical facility is equipped with advanced equipment (for example, a 32-ch
Acute Myeloid Leukemia (AML) Diagnosis
15160.8 help13727
Consolidation treatment of acute myeloid leukemia
67618 help59196
Radiation therapy of brain at Acute myeloid leukemia (AML) with brain damage
31002 help28002

Tel Aviv Sourasky Medical Center

9.9/10
location_onIsrael, Tel Aviv

Department of Hematology

The Tel Aviv Sourasky Medical Center is the second largest and one of the most advanced healthcare and research facilities in Israel. It began its work in 1961, but it is still popular among the local population and attracts thousands of international patients. The multidisciplinary medical center covers an area of ​​150,000 m&s
Acute Myeloid Leukemia (AML) Diagnosis
16937
Consolidation treatment of acute myeloid leukemia
76743
Radiation therapy of brain at Acute myeloid leukemia (AML) with brain damage
36156

University Hospital Freiburg

9.7/10
location_onGermany, Freibung

Department of Hematology and Oncology

The University Hospital Freiburg is famous for its rich history and is one of the oldest and most prestigious medical facilities in Germany (one of the three best medical institutions in the country). The hospital was based on the Faculty of Medicine of the Albert Ludwig University of Freiburg, which celebrated its 550th anniver
Acute Myeloid Leukemia (AML) Diagnosis
16986
Allogeneic bone marrow transplantation in acute myeloid leukemia
291159
Consolidation treatment of acute myeloid leukemia
88973

University Hospital Heidelberg

9.8/10
location_onGermany, Heidelberg

Department of Hematology, Oncology, Adult and Pediatric Rheumatology

According to the Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all field
Acute Myeloid Leukemia (AML) Diagnosis
0
Allogeneic bone marrow transplantation in acute myeloid leukemia
0
Consolidation treatment of acute myeloid leukemia
0

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Gastroenterology, Hematology, Oncology, Hepatology, Infectology, Rheumatology and Clinical Immunology

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Acute Myeloid Leukemia (AML) Diagnosis
14691
Allogeneic bone marrow transplantation in acute myeloid leukemia
231760
Consolidation treatment of acute myeloid leukemia
73259

University Hospital RWTH Aachen

8.7/10
location_onGermany, Aachen

Department of Oncology and Hematology

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Acute Myeloid Leukemia (AML) Diagnosis
17048
Allogeneic bone marrow transplantation in acute myeloid leukemia
291306
Consolidation treatment of acute myeloid leukemia
88970

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Hematology and Oncology

According to the Focus magazine, the University Hospital Erlangen ranks among the top German medical facilities! The hospital is one of the leading medical facilities in Bavaria and offers the highest level of medical care, which is characterized by the close intertwining of clinical activities with research and training of medi
Acute Myeloid Leukemia (AML) Diagnosis
16347
Allogeneic bone marrow transplantation in acute myeloid leukemia
271493
Consolidation treatment of acute myeloid leukemia
72209

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Hematology and Oncology

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Acute Myeloid Leukemia (AML) Diagnosis
14759
Allogeneic bone marrow transplantation in acute myeloid leukemia
231809
Consolidation treatment of acute myeloid leukemia
73134

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Hematology, Oncology and Pulmonology

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Acute Myeloid Leukemia (AML) Diagnosis
14538
Allogeneic bone marrow transplantation in acute myeloid leukemia
231853
Consolidation treatment of acute myeloid leukemia
73358

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Charité Comprehensive Cancer Center

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Acute Myeloid Leukemia (AML) Diagnosis
14481
Allogeneic bone marrow transplantation in acute myeloid leukemia
232307
Consolidation treatment of acute myeloid leukemia
73278

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Oncology, Hematology, Rheumatology and Immunoncology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Acute Myeloid Leukemia (AML) Diagnosis
17071
Allogeneic bone marrow transplantation in acute myeloid leukemia
291153
Consolidation treatment of acute myeloid leukemia
88985

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Oncology and Hematology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Acute Myeloid Leukemia (AML) Diagnosis
16914
Allogeneic bone marrow transplantation in acute myeloid leukemia
291050
Consolidation treatment of acute myeloid leukemia
76410

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of Oncology, Hematology and Palliative Care

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Acute Myeloid Leukemia (AML) Diagnosis
14497
Allogeneic bone marrow transplantation in acute myeloid leukemia
232217
Consolidation treatment of acute myeloid leukemia
73143

About the disease

Acute myeloid leukemia is a cancer of blood cells, which develops in the bone marrow, where blood cells are produced. AML tends to progress rapidly and can metastasize to lymph nodes and central nervous system. In some cases, it can also spread to liver and spleen.

AML develops in myeloid cells responsible for forming red and white blood cells. Myeloid cells become malignant when they start to multiply abnormally and block development of healthy blood cells. Such abnormal blood cells are also known as immature blasts, as they keep dividing when they should have stopped to allow new blood cells develop.

According to American Cancer Society, there are approximately 21,380 new cases of AML registered annually in the USA. It is more common in people over 45 years of age. In rare cases, AML affects children and their survival rates are much higher than in adults. It is more common in men.

Although the exact cause for AML has not been determined yet, smoking is considered one of the leading risk factors for this disease. It can be explained by the fact that smoke substances easily enter the bloodstream and affect the blood cells. Tobacco consumption is considered more dangerous than cigarettes as it spreads through the bloodstream easier. It can also be caused by previous radiation exposure and chemotherapy. Certain genetic blood disorders, which affect myeloid cells, can also cause development of AML.

Symptoms

  • Fatigue
  • Weight loss
  • Headaches
  • Decreased appetite
  • Dizziness
  • Lightheadedness
  • Frequent nose bleeding
  • Long healing wounds and bruises
  • Vomiting

Diagnosis

  • Blood test is generally used as the first measure if there is a suspicion for AML. It determines if a person has abnormal amount of white and red blood cells in the bloodstream. It can also rule out the possibility of anemia and other blood diseases.
  • Bone marrow biopsy is used to confirm the diagnosis and determine the stage of AML. It can also determine the type of leukemia, if it has not been determined yet that a patient has acute myeloid leukemia.
  • MRI and CT scan of other organs are used if there is suspicion that AML has metastasized to lungs, liver or brain.

Treatment

  • High-intensity induction chemotherapy is considered to be the main treatment for AML, as it is impossible to resect and shrink this type of cancer. There are several effective chemotherapy drugs, designed specifically for AML treatment, which are usually able to kill the majority of cancerous cells. It is especially effective at the beginning stages of AML.
  • Consolidation treatment is usually used after the first induction therapy to kill the remaining part of immature blasts, which have not been reached by induction therapy. It is usually given through the injection into the vein and is applied after the patient recovered from initial induction therapy.
  • Radiation therapy of brain is primarily used if AML has spread to the brain. There can be one or several courses of radiation, depending on the stage of cancer progression.
  • Stem cells transplantation is used if the abnormal division of blood cells in the bone marrow is absolutely irreversible and cannot be improved after chemotherapy. In this case, a patient undergoes transplantation of healthy stem cells from the donor, which tissue type must be similar to the type of a patient. Usually, relatives and people with similar DNA are the best matches for this type of therapy.

 

Author: Dr. Nadezhda Ivanisova

  




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