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Hematology: Diagnostics and Symptomatic Treatment of Von Willebrand Disease with Willebrand Factor and Factor VIII

Von Willebrand disease (VWD) is a hereditary disease manifested by bleeding disorders. According to statistics, the pathology is diagnosed at a rate of 1 to 2 cases per 10 thousand persons. The cause of the disorder is deficiency or dysfunction of von Willebrand factor, a protein responsible for platelet "clotting". Subject to timely treatment, the vast majority of forecasts on the disease is favorable.

Diagnostics

BV can be suspected based on the clinical data and family history. To confirm the diagnosis and exclude similar diseases, the patient is prescribed:

  • complete blood count,
  • blood chemistry,
  • analysis for haematuria,
  • abdominal ultrasound,
  • integrated CT/MRI,
  • bone marrow aspiration biopsy (trepanobiopsy of the ilium wing).

Therapies

The treatment is carried out with the appearance of bleeding or on the eve of surgical interventions (to prevent complications). To restore the normal blood clotting, the patient is prescribed the transfusion therapy (a single administration of blood products with a high content of von Willebrand factor and coagulation factor VIII). The hemostasis values bounce back 1 to 2 days after the transfusion.

Some manifestations of the disease (bleeding from the nose or from the oral mucosa, uterine bleeding) are docked with additional medicines:

  • fibrinolysis inhibitors,
  • local hemostatics.

The treatment duration is determined by severity of the condition. Upon cycle completion, the patient is given advice on further treatment.

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Age: 15 years or older

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Vivantes Neukölln Hospital Berlin

10/10 from 23 Votes

Department of Hematology, Oncology and Palliative Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #358150

The Department of Hematology, Oncology and Palliative Medicine offers the full range of services in these focuses. The department specializes in the treatment of all blood diseases, oncological diseases of various organs and palliative care.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Berlin

University Hospital Rechts der Isar of the Munich Technical University

10/10 from 70 Votes

Department of Gastroenterology and Endocrinology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #178867

The Department of Internal Medicine II – Gastroenterology at the university hospital Klinikum rechts der Isar offers the full range of modern methods of endoscopic and sonographic examinations and performs all relevant gastroenterological and endocrine function examinations.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

Academic Hospital Harlaching Munich

9.2/10 from 32 Votes

Department of Hematology, Oncology and Palliative Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #144109

The Department of Hematology, Oncology and Palliative Medicine primarily treats patients with cancer or hematologic diseases. The treatment is based on the comprehensive approach, which includes both physical and psychosocial aspects. The department is part of the interdisciplinary Cancer Center Munich Süd.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

Academic Hospital Asklepios Barmbek Hamburg

10/10 from 23 Votes

Department of Oncology, Hematology and Palliative Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #356234

The Department of Oncology, Hematology and Palliative Care offers the full range of services in the relevant medical fields. The department is certified by the German Cancer Society, which confirms the outstanding quality of medical care.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Hamburg

Academic Hospital Schwabing Munich

8.5/10 from 7 Votes

Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectiology and Tropical Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #177483

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

Academic Hospital Neuperlach Munich

9.8/10 from 11 Votes

Department of Hematology and Oncology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #144977

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

University Hospital Frankfurt am Main

9.5/10 from 97 Votes

Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #76435

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology specializes in the treatment of all diseases of the hematopoietic system and solid tumors.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

St. Vincentius Clinic Karlsruhe

9.8/10 from 23 Votes

Department of Hematology, Oncology, Immunology and Palliative Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #336308

he Department of Hematology, Oncology, Immunology and Palliative Care specializes in the diagnosis and treatment of patients suffering from blood diseases, oncological and immunological diseases. Palliative medicine also belongs to the main directions of the department.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Karlsruhe

University Hospital Muenster

8.8/10 from 78 Votes

Department of Hematology, Hemostaseology, Oncology and Pneumology (Medical Department A)

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #151035

The Medical Department A (Med A) at the University Hospital Muenster deals with the treatment of all kinds of cancer of various organs, including the hematopoietic system.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Muenster

University Hospital Duesseldorf

9.9/10 from 71 Votes

Department of Hematology, Oncology and Clinical Immunology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #166181

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Tel Aviv Sourasky Medical Center

9.9/10 from 23 Votes

Department of Hematology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #331095

The Department of Hematology at the Tel Aviv Sourasky Medical Center provides expert care for patients with a variety of blood disorders, including malignant hematological diseases.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Israel
location_searchingCity: Tel Aviv

University Hospital Cologne

9.8/10 from 82 Votes

Department of Oncology, Hematology, Clinical Infectiology, Clinical Immunology, Hemostasis, Intensive Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #165623

The Department of Oncology, Hematology, Clinical Infectiology, Clinical Immunology, Hemostasis, Intensive Care deals with the treatment of various internal diseases.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Cologne
certificate

Hannover Medical School

9.8/10 from 43 Votes

Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #246981

The Department of Hematology, Hemostasiology, Oncology and Stem Cell Transplantation at the Hannover Medical School specializes in diagnosis and treatment of the entire range of malignant tumors, benign hematological diseases and blood coagulation disorders.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Hannover
certificate

Hospital Waldbrol Oberberg

9.7/10 from 23 Votes

Department of Hematology, Oncology, Palliative Medicine and Sleep Laboratory

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #286472

The Department of Hematology, Oncology, Palliative Medicine, Pneumology and Somnology at the District Hospital of Waldbröl (Medical Department III) has 30 beds. A competent treatment is provided by three medical specialists in the field of hematology and oncology and a professional anesthesiologist.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Waldbrоl

Vivantes Am Urban Hospital Berlin

9.7/10 from 23 Votes

Department of Hematology and Oncology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #340094

Clinical areas of the Department of Hematology and Oncology include acute leukemias, lymphomas (lymph node cancer), multiple myeloma, lung cancer, testicular cancer, metastatic breast cancer and malignant gastrointestinal diseases such as stomach cancer and colon cancer.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Berlin

Vivantes Humboldt Hospital Berlin

9.7/10 from 23 Votes

Department of Oncology and Hematology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #338023

The Department of Oncology provides complex treatment and care for oncological diseases and cancerous blood diseases (hematology).  It offers a full range of services in the field of these two areas. The treatment is conducted in outpatient and inpatient settings. The focus is on the needs of the patients.


Duration: 5 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Berlin




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