Hematology:
Diagnostics and Symptomatic Treatment of Von Willebrand Disease with Willebrand Factor and Factor VIII

Von Willebrand disease (VWD) is a hereditary disease manifested by bleeding disorders. According to statistics, the pathology is diagnosed at a rate of 1 to 2 cases per 10 thousand persons. The cause of the disorder is deficiency or dysfunction of von Willebrand factor, a protein responsible for platelet "clotting". Subject to timely treatment, the vast majority of forecasts on the disease is favorable.

Diagnostics

BV can be suspected based on the clinical data and family history. To confirm the diagnosis and exclude similar diseases, the patient is prescribed:

  • complete blood count,
  • blood chemistry,
  • analysis for haematuria,
  • abdominal ultrasound,
  • integrated CT/MRI,
  • bone marrow aspiration biopsy (trepanobiopsy of the ilium wing).

Therapies

The treatment is carried out with the appearance of bleeding or on the eve of surgical interventions (to prevent complications). To restore the normal blood clotting, the patient is prescribed the transfusion therapy (a single administration of blood products with a high content of von Willebrand factor and coagulation factor VIII). The hemostasis values bounce back 1 to 2 days after the transfusion.

Some manifestations of the disease (bleeding from the nose or from the oral mucosa, uterine bleeding) are docked with additional medicines:

  • fibrinolysis inhibitors,
  • local hemostatics.

The treatment duration is determined by severity of the condition. Upon cycle completion, the patient is given advice on further treatment.

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University Hospital Bonn

8.6/10 from 150 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Bonn

Price 6943.00

University Hospital Cologne

8.7/10 from 82 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department I for Internal Medicine of the University Hospital Cologne deals with the treatment of patients with various internal diseases. This includes in particular the following fields: Oncology, Hematology, Clinical infectology, Clinical immunology, Hemostasis, Intensive care.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Cologne

Price 6954.00

University Hospital Frankfurt

7.5/10 from 97 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Hematology, Oncology, Hemostasis, Rheumatology and Infectology at the University Hospital Frankfurt specializes in the treatment of all diseases of the hymatopoietic system and solid tumors.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 8339.00

Charite University Hospital Berlin

9/10 from 95 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Charité Comprehensive Cancer Center integrates the clinical and research activities for all Charité departments and institutes dealing with Cancer. The director of the Charité Comprehensive Cancer Center is Prof. Dr. med. Ulrich Keilholz.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Berlin

Price 9704.00

University Hospital Heidelberg

9/10 from 57 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Hematology, Oncology and Rheumatology at the Heidelberg University Hospital makes every effort to provide medical care of the highest quality to the patients with oncologic and rheumatologic diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Heidelberg

Price 8225.00

Krankenhaus Nordwest

9.5/10 from 24 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

Department of Oncology and Hematology of Krankenhaus Nordwest offers a wide range of medical services, including diagnosis, therapy and treatment of oncological diseases or diseases closely associated with the circulatory system.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 6314.00

Städtisches Klinikum Schwabing

8.5/10 from 7 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 6323.00

RWTH University Hospital Aachen

8.7/10 from 41 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Aachen

Price 6635.00

Alfried Krupp Hospital in Essen-Ruettenscheid

9.9/10 from 42 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Essen

Price 5854.00

University Hospital Dusseldorf

9.9/10 from 71 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes. .


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Price 8257.00

Hannover Medical School, MHH

9.8/10 from 43 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The clinic of hematology, hemostasis, oncology and stem cell transplantation is a leading therapeutic clinic of the Medical Institute of Hannover for patients with solid tumor and systemic diseases, with other partially benign diseases of the hematopoietic system, as well as bleeding disorders.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Hannover

Price 6904.00

Städtisches Klinikum Neuperlach

9.8/10 from 11 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 6458.00

Gummersbach District Hospital of the Klinikum Oberberg

9.6/10 from 23 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The Department of Internal Medicine II at the Klinikum Oberberg in Gummersbach focuses on diagnosis and treatment of oncological and hematological diseases.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Gummersbach

Price 5702.00

University Hospital Halle (Saale)

9.5/10 from 78 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

Department of Hematology and Oncology at the University Hospital of Halle (Saale) has many years of experience in diagnostics and treatment of hematological and oncological diseases. It completely covers the whole range of hematology and oncology.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Halle

Price 6980.00

UKGM Gießen

9.5/10 from 35 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

The department of internal medicine IV and V includes general internal medicine and a number of priority areas of this subject. The clinic offers a wide range of newest innovative treatments especially in the fields of medical oncology, hematology and palliative care.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Giessen

Price 6353.00

University Hospital Wurzburg

9.2/10 from 38 Votes

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII

Medical Clinic II provides inpatient and outpatient treatment to patients with hematologic/oncologic, gastrointestinal and rheumatological/immunological diseases. In March 2005, it opened a new center for stem cell transplantation.


Duration 5 days
Type of Treatment: Outpatient
location_onCountry: Germany
location_searchingCity: Würzburg

Price 7199.00