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Hematology: Diagnostics and Symptomatic Treatment of Von Willebrand Disease with Willebrand Factor and Factor VIII

Von Willebrand disease (VWD) is a hereditary disease manifested by bleeding disorders. According to statistics, the pathology is diagnosed at a rate of 1 to 2 cases per 10 thousand persons. The cause of the disorder is deficiency or dysfunction of von Willebrand factor, a protein responsible for platelet "clotting". Subject to timely treatment, the vast majority of forecasts on the disease is favorable.

Diagnostics

BV can be suspected based on the clinical data and family history. To confirm the diagnosis and exclude similar diseases, the patient is prescribed:

  • complete blood count,
  • blood chemistry,
  • analysis for haematuria,
  • abdominal ultrasound,
  • integrated CT/MRI,
  • bone marrow aspiration biopsy (trepanobiopsy of the ilium wing).

Therapies

The treatment is carried out with the appearance of bleeding or on the eve of surgical interventions (to prevent complications). To restore the normal blood clotting, the patient is prescribed the transfusion therapy (a single administration of blood products with a high content of von Willebrand factor and coagulation factor VIII). The hemostasis values bounce back 1 to 2 days after the transfusion.

Some manifestations of the disease (bleeding from the nose or from the oral mucosa, uterine bleeding) are docked with additional medicines:

  • fibrinolysis inhibitors,
  • local hemostatics.

The treatment duration is determined by severity of the condition. Upon cycle completion, the patient is given advice on further treatment.

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Vivantes Neukölln Hospital Berlin

10/10 from23 Votes
location_onGermany, Berlin

Department of Hematology, Oncology and Palliative Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #358150

The Department of Hematology, Oncology and Palliative Medicine offers the full range of services in these focuses. The department specializes in the treatment of all blood diseases, oncological diseases of various organs and palliative care.

Include:
people Interpreter up to 10 hours.
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book Insurance against increased costs in case of complications with a cover of 200,000 €

St. Vincentius Clinic Karlsruhe

9.8/10 from23 Votes
location_onGermany, Karlsruhe

Department of Hematology, Oncology, Immunology and Palliative Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #336308

he Department of Hematology, Oncology, Immunology and Palliative Care specializes in the diagnosis and treatment of patients suffering from blood diseases, oncological and immunological diseases. Palliative medicine also belongs to the main directions of the department.

Charite University Hospital Berlin

9/10 from95 Votes
location_onGermany, Berlin
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Charité Comprehensive Cancer Center

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #229117

The Charite Comprehensive Cancer Center integrates all departments and units dealing with cancer treatment. The center offers patients the most advanced comprehensive cancer treatment.

University Hospital Rechts der Isar of the Munich Technical University

10/10 from70 Votes
location_onGermany, Munich
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Department of Hematology and Oncology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #126075

The Department of Internal Medicine III at the university hospital Klinikum rechts der Isar focuses on the area of hematology and internistic oncology. Every year an experienced and dedicated team of doctors provides treatment to more than 7. 000 patients from both Germany and abroad.

Academic Hospital Neuperlach Munich

9.8/10 from11 Votes
location_onGermany, Munich

Department of Hematology and Oncology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #144977

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.

University Hospital Frankfurt am Main

10/10 from97 Votes
location_onGermany, Frankfurt am Main
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Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #76435

The Department of Hematology, Oncology, Hemostaseology, Rheumatology and Infectiology specializes in the treatment of all diseases of the hematopoietic system and solid tumors.

University Hospital Muenster

9.8/10 from78 Votes
location_onGermany, Muenster
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Department of Hematology, Hemostaseology, Oncology and Pneumology (Medical Department A)

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #151035

The Medical Department A (Med A) at the University Hospital Muenster deals with the treatment of all kinds of cancer of various organs, including the hematopoietic system.

HELIOS Clinic Krefeld

9.7/10 from38 Votes
location_onGermany, Krefeld

Department of Gastroenterology, Hepatology, Neurogastroenterology, Infectology, Hematology, Oncology and Palliative Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #388249

The Department of Gastroenterology, Hepatology, Neurogastroenterology, Infectology, Hematology, Oncology and Palliative Care offers the full range of services in these medical fields.

Academic Hospital Harlaching Munich

9.2/10 from32 Votes
location_onGermany, Munich
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Department of Hematology, Oncology and Palliative Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #144109

The Department of Hematology, Oncology and Palliative Medicine primarily treats patients with cancer or hematologic diseases. The treatment is based on the comprehensive approach, which includes both physical and psychosocial aspects. The department is part of the interdisciplinary Cancer Center Munich Süd.

Academic Hospital Asklepios Barmbek Hamburg

9.5/10 from23 Votes
location_onGermany, Hamburg

Department of Oncology, Hematology and Palliative Care

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #356234

The Department of Oncology, Hematology and Palliative Care offers the full range of services in the relevant medical fields. The department is certified by the German Cancer Society, which confirms the outstanding quality of medical care.

Vivantes Humboldt Hospital Berlin

9.7/10 from23 Votes
location_onGermany, Berlin

Department of Oncology and Hematology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #338023

The Department of Oncology provides complex treatment and care for oncological diseases and cancerous blood diseases (hematology).  It offers a full range of services in the field of these two areas. The treatment is conducted in outpatient and inpatient settings. The focus is on the needs of the patients.

PAN Clinic Cologne

9/10 from14 Votes
location_onGermany, Cologne
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Department of Internal Medicine and Cardiology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #36931

The Department of Internal Medicine and Cardiology at the PAN Clinic on Neumarkt covers the whole range of general, conservative and interventional cardiology, as well as internal medicine.

Academic Hospital Schwabing Munich

8.5/10 from7 Votes
location_onGermany, Munich
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Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectiology and Tropical Medicine

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #177483

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.

University Hospital Duesseldorf

9.9/10 from71 Votes
location_onGermany, Duesseldorf
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Department of Hematology, Oncology and Clinical Immunology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #166181

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes.

Tel Aviv Sourasky Medical Center

9.9/10 from23 Votes
location_onIsrael, Tel Aviv

Department of Hematology

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #331095

The Department of Hematology at the Tel Aviv Sourasky Medical Center provides expert care for patients with a variety of blood disorders, including malignant hematological diseases.

Hannover Medical School

9.8/10 from43 Votes
location_onGermany, Hannover
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Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation

Diagnosis and symptomatic treatment of von Willebrand disease with Willebrand factor and factor VIII #246981

The Department of Hematology, Hemostasiology, Oncology and Stem Cell Transplantation at the Hannover Medical School specializes in diagnosis and treatment of the entire range of malignant tumors, benign hematological diseases and blood coagulation disorders.




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