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In vitro fertilization (IVF) short protocol (616385) | Sheba Medical Center Ramat Gan - BookingHealth
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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician&nbsp;for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><strong>The type of protocol (the long or short one) is selected by the physician.<\/strong><\/p>\n\n<p style=\"text-align: justify;\"><strong><u>Service support<\/u><\/strong><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. We provide you with an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, translating medical reports.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">Results of hormone blood tests (if available)<\/li>\n\t<li style=\"text-align: justify;\">Pelvic ultrasoud (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li style=\"text-align:justify\">Initial presentation in the clinic<\/li>\n\t<li style=\"text-align:justify\">Case history taking<\/li>\n\t<li style=\"text-align:justify\">Review of medical records<\/li>\n\t<li style=\"text-align:justify\">General physical examination<\/li>\n\t<li style=\"text-align:justify\"><strong>Laboratory tests:&nbsp;<\/strong>\n\t<ul style=\"list-style-type:circle\">\n\t\t<li>Complete blood count&nbsp;<\/li>\n\t\t<li>General urine test<\/li>\n\t\t<li>Biochemical blood test<\/li>\n\t\t<li>Inflammation markers<\/li>\n\t\t<li>Blood coagulation test&nbsp;<\/li>\n\t\t<li>Immune status<\/li>\n\t\t<li>Hormone levels:\n\t\t<ul>\n\t\t\t<li>FSH<\/li>\n\t\t\t<li>LH<\/li>\n\t\t\t<li>Androgens<\/li>\n\t\t\t<li>Progesterone<\/li>\n\t\t\t<li>Prolactin<\/li>\n\t\t\t<li>TSH-basal, fT3, fT4&nbsp;<\/li>\n\t\t<\/ul>\n\t\t<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li style=\"text-align:justify\">Ultrasound examination of abdomen and small pelvis organs&nbsp;<\/li>\n\t<li style=\"text-align:justify\">Transvaginal ultrasound scan<\/li>\n\t<li style=\"text-align:justify\">Gynecological examination<\/li>\n\t<li style=\"text-align:justify\">Colposcopy<\/li>\n\t<li style=\"text-align:justify\">Hormonal stimulation&nbsp;<\/li>\n\t<li style=\"text-align:justify\"><strong>In vitro fertilization (IVF)<\/strong><\/li>\n\t<li style=\"text-align:justify\">Nursing services<\/li>\n\t<li style=\"text-align:justify\">Consultations of related specialists<\/li>\n\t<li style=\"text-align:justify\">Treatment by head doctor and all leading experts<\/li>\n\t<li style=\"text-align:justify\">Explanation of the individual treatment plan<\/li>\n<\/ul>\n\n<p style=\"text-align:justify\"><em>All aspects of the program can be discussed with a medical advisor.<\/em><\/p>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align: justify;\">You <strong>arrive in the hospital<\/strong> on the first day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician&nbsp;for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. 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In vitro fertilization (IVF) short protocol

Sheba Medical Center Ramat Gan

Ramat Gan, Israel
Program id # 616385
Doctor photo
Prof. Dr. med. Raoul Orvieto
Department of Reproductive Medicine
Specialized in: reproductive medicine

The program includes:

  • Initial presentation in the clinic
  • Case history taking
  • Review of medical records
  • General physical examination
  • Laboratory tests: 
    • Complete blood count 
    • General urine test
    • Biochemical blood test
    • Inflammation markers
    • Blood coagulation test 
    • Immune status
    • Hormone levels:
      • FSH
      • LH
      • Androgens
      • Progesterone
      • Prolactin
      • TSH-basal, fT3, fT4 
  • Ultrasound examination of abdomen and small pelvis organs 
  • Transvaginal ultrasound scan
  • Gynecological examination
  • Colposcopy
  • Hormonal stimulation 
  • In vitro fertilization (IVF)
  • Nursing services
  • Consultations of related specialists
  • Treatment by head doctor and all leading experts
  • Explanation of the individual treatment plan

All aspects of the program can be discussed with a medical advisor.

How program is carried out

You arrive in the hospital on the first day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.

The reproductologist will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the physician will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your physician for advice at any time.

For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound scan (up to 3 times).

Stages of treatment

Ovarian stimulation. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound scan is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.

The physician will appoint the day of visiting the hospital. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman has a stimulating (trigger) injection of hCG (human chorionic gonadotropin).

Egg collection. In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men – the ICSI procedure).

Fertilization. 2-6 hours after egg collection, eggs are fertilized with the husband’s sperm. This is a laboratory procedure and no patient involvement is required.

Embryo culture. Fertilized eggs will be cultured for 1-5 days. According to patients’ needs and embryo status, best 1-3 embryos can be transferred to the womb.

Preimplantation genetic diagnosis. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.

Embryo transfer. This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the hospital and can return home on the same day.

Pregnancy test. This test can be done 14 days after the embryo transfer.

The type of protocol (the long or short one) is selected by the physician.

Service support

We fully support your trip, regardless of the chosen program. We provide you with an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, translating medical reports.

Required documents

  • Medical records
  • Results of hormone blood tests (if available)
  • Pelvic ultrasoud (if available)

Service

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About the department

The Department of Reproductive Medicine at the Sheba Medical Center Ramat Gan ensures high quality of all modern procedures for fertility treatment. One of the most popular methods for conception of a long-awaited pregnancy is in vitro fertilization (IVF). The department's specialists first performed the IVF procedure in 1982 and since then they have been successfully practicing it for couples who cannot conceive a child naturally. As of today, the department performs more than 1,000 IVF procedures annually, while the treatment success rates are one of the best in the world. During the therapeutic process, the patients are provided with maximum comfort, confidentiality and the highest quality of medical services. The Chief Physician is Prof. Dr. med. Raoul Orvieto.

The treatment is preceded by a consultation with the attending physician. He clarifies information about the duration of infertility, studies the anamnesis of a woman and a man, prescribes the necessary diagnostic tests, the results of which will become the basis for the development of an individual treatment regimen aimed at conceiving and carrying a pregnancy. A decisive role in the effectiveness of therapy is the precise determination of the causes of infertility, the elimination of which will help a woman to become pregnant. The IVF procedure is mostly indicated for couples who cannot conceive a child during a year of regular sexual activity without the use of contraceptives, women with hormonal disorders, which prevent the normal maturation of eggs and are not corrected by conservative treatment, women with fallopian tube obstruction. In the case of insufficient sperm motility and low sperm concentration in the male seminal fluid, IVF is also effective. If necessary, IVF can be performed using cryopreserved eggs and sperm in patients who have undergone chemotherapy, radiation therapy or other treatments, which suppress ovarian or testicular function. The department also practices IVF using donor germ cells.

The process of artificial insemination consists of combining an egg and a sperm outside the woman's body, and therefore this technique is sometimes called "test tube fertilization". In most cases, the IVF procedure involves the use of the parents' own germ cells, which guarantees 100% genetic match. The unique experience and clinical skills of the department's fertility doctors allow the patients to conceive a pregnancy on the first try. In rare cases, repeated IVF may be required – this fact is determined at the planning stage of the procedure.

The IVF procedure consists of the following stages:

  • Superovulation stimulation
  • Follicular puncture 
  • Oocyte insemination with specially prepared sperm
  • Preimplantation genetic diagnosis before embryo transfer into the uterine cavity in order to exclude genetic pathologies
  • Embryo culture (fertilized eggs grow and develop in a special nutrient medium for about 3-5 days, after which the doctor selects the highest quality embryos)
  • Embryo transfer into the uterine cavity (usually 1-2 embryos are used)
  • Pregnancy test for its confirmation

The department's range of medical services includes:

  • In vitro fertilization (IVF) procedure
  • Percutaneous sperm aspiration
  • Assisted hatching
  • Controlled ovarian stimulation
  • Testicular sperm extraction
  • Embryo cryopreservation
  • Egg and sperm donation
  • Microsurgical epididymal sperm aspiration
  • Zygote intrafallopian transfer (ZIFT)
  • Correction of certain factors of infertility in women (for example, cysts, fallopian tube obstruction)
  • Sperm count improvement in men
  • Fertility preservation in cancer patients 
  • Genetic counseling, including preimplantation genetic diagnosis
  • Other diagnostic and therapeutic options

Curriculum vitae

Prof. Dr. med. Raoul Orvieto is a highly qualified Israeli specialist in the field of assisted reproductive technologies. The doctor's professional interests include the treatment of male and female infertility, IVF, egg donation, preimplantation genetic diagnosis, various aspects of controlled ovarian hyperstimulation, etc. Prof. Orvieto has over 20 years of successful clinical experience. He is the author and co-author of numerous scientific publications, as well as a lecturer at the Faculty of Medicine of the Ben-Gurion University of the Negev.

Higher Education and Professional Сareer

  • 1980 - 1986 Doctoral Degree, Hebrew University of Jerusalem.
  • Master's Degree in Obstetrics and Gynecology at the Sackler School of Medicine of the Tel Aviv University.
  • 1992 - 1998 Specialization in Gynecology and Obstetrics, Rabin Medical Center, Petah Tikva, Israel.
  • 1998 - 2005 Senior Physician in the Department of Gynecology, Rabin Medical Center, Petah Tikva, Israel.
  • 2002 - 2005 Head of the Department of Male Infertility, Rabin Medical Center, Petah Tikva, Israel.
  • 2005 - 2013 Head of the IVF Center, Barzilai Medical Center, Ashkelon, Israel.
  • Since 2013 Head of the Department of Reproductive Medicine at the Sheba Medical Center Ramat Gan.

Academic Career

  • Professor at the Faculty of Medicine, Ben-Gurion University of the Negev.

Memberships in Professional Societies

  • Israel Medical Association.
  • Israel Society of Obstetrics and Gynecology.
  • Israeli Fertility Association.
  • Israeli Society of Contraception and Sexual Health.
  • American Society for Reproductive Medicine.

Photo of the doctor: (c) Sheba Medical Center


About hospital

The Sheba Medical Center Ramat Gan is the largest and leading Israeli hospital, which has also won wide recognition in the international medical arena. The hospital was founded in 1948 and today it is proud of its long and extremely successful clinical experience. The medical facility has 159 specialized departments, outpatient clinics and centers, as well as 75 laboratories. The infrastructure of the center forms a solid basis for the accurate diagnostics, comprehensive and the most effective treatment of pathologies in all fields of modern medicine. 

According to the prestigious American Newsweek magazine, the medical center ranked among the top ten best hospitals in the world in 2019 – the rating is based on the efficiency of medical care, the level of service, compliance with international quality standards. In addition, the medical centre is the holder of the international JCI certificate, which is awarded only to the best hospitals all over the world.

The medical complex provides patients with the most advanced medical treatment and individual approach to each clinical case. If necessary, the patient can take part in clinical trials of new pharmaceuticals or treatment methods. The patients are offered high-tech medicine. For example, it houses the only virtual reality Rehabilitation Center in the world, as well as offers exclusive and progressive methods of imaging diagnostics for patients suffering from cancers and cardiovascular diseases.

One of the leading fields of the medical center is oncology. Cancer of various localizations is treated within the specialized Cancer Center. Thanks to the hospital's own unique developments in the field of oncology and cooperation with the University of Texas MD Anderson Cancer Center, the doctors practice innovative treatment protocols, which allow them to achieve complete cure or long-term remission even in the cases that are considered hopeless in many hospitals around the world.

Certainly, the key role in the success of clinical practice is also played by the presence of highly qualified personnel – the hospital employs dozens of leading doctors, including world-class professionals. Many doctors are lecturers at the Sackler School of Medicine of the Tel Aviv University. In addition to the treatment of patients, they are engaged in research activities and make an invaluable contribution to the development of medicine in Israel and around the world.

The hospital admits annually more than 430,000 patients for the diagnostics and treatment on an inpatient basis, while the number of outpatients reaches 160,000. These figures speak for themselves and confirm the authority of the medical center, which is ready to provide high-quality medical care to both Israeli citizens and foreign patients from all over the world. The hospital also performs about 50,000 surgical interventions, as well as more than 11,000 babies are born in the delivery rooms of the medical center every year.

The Sheba Medical Center Ramat Gan is rightfully considered the world leader in the field of medical care and has all the necessary medical and technical resources for providing both diagnostic and therapeutic procedures of any complexity – some of them are not available even in the developed countries of Europe and the USA.

Photo: (c) Sheba Medical Center, (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the Sheba Medical Center Ramat Gan live in cozy rooms with a high level of comfort. Each patient room has an ensuite bathroom with shower and toilet, with all the necessary hygiene items. The furnishing of the rooms includes a comfortable automatically adjustable bed, a bedside table, a wardrobe, a telephone, a TV, an air conditioner. Wi-Fi access is also available in the patient rooms. The center has special rooms for children. The special atmosphere of coziness and kindness allows young patients to feel as comfortable as possible.

Meals and Menus

The patient and the accompanying person are offered tasty and balanced three meals a day. If for some reason you do not eat all foods, you will be offered an individual menu. Please inform the medical staff about your food preferences prior to treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Accompanying person

During the inpatient program, the accompanying person can live with the patient in a patient room or a hotel of his choice. Our managers will help you choose the most suitable option.

Hotel

During an outpatient program, the patient can stay at the hotel on the territory of the medical center or at the hotel of his choice. Our managers will help you choose the most suitable option.