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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align: justify;\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align: justify;\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.<\/p>\n\n<p style=\"text-align: justify;\">When your complete blood count returns to normal, your doctor will schedule your <strong>discharge from the department<\/strong>. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. 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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>bone marrow transplant procedure<\/strong> is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.<\/p>\n\n<p style=\"text-align: justify;\">During the <strong>period of healthy bone marrow engraftment<\/strong>, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.<\/p>\n\n<p style=\"text-align: justify;\">A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. 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Allogeneic bone marrow transplantation in acute myeloid leukemia in Charite University Hospital Berlin
needle biopsy of the bone marrow with histological:
cytochemistry
immunocytology
cytogenetics (Philadelphia chromosome detection)
molecular biology
biopsy and histological examination of CSF
examination by experts of:
cardiology
otolaryngology
immunology
ophthalmology
registration in the European bone marrow donor base
conducting high-dose chemotherapy
allogeneic bone marrow transplantation from unrelated donor
isolation by neutropenic precautions
symptomatic treatment
control examinations
the cost of essential medicines and materials
nursing services
full hospital accommodation
explanation of future recommendations
How program is carried out
During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.
Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.
Before the procedure, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.
The bone marrow transplant procedure is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.
During the period of healthy bone marrow engraftment, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.
A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.
When your complete blood count returns to normal, your doctor will schedule your discharge from the department. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.
Required documents
Medical records
MRI/CT scan (not older than 3 months)
Bone marrow biopsy results (if available)
Service
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About the department
Charité Comprehensive Cancer Center at the Charite University Hospital Berlin offers patients the full range of classical and innovative examinations, treatment of malignant diseases of all organs and anatomical structures of the human body. The spectrum is complemented by follow-up medical care, rehabilitation, modern schemes for the prevention and early detection of malignant diseases. An important component of the therapeutic process in the center is psycho-oncological care. The centerdals with the treatment of patients of all age groups, ranging from small children to elderly patients. The center is headed by Prof. Dr. med. Ulrich Keilholz.
The center takes part in many leading clinical researches on the optimization of existing and the development of innovative therapeutic techniques. It integrates the work of all departments of the hospital engaged in the treatment of various types of cancers, therefore, the specialists from all medical fields cooperate closely here.
The center specializes in the diagnostics and treatment of the following malignant diseases:
Eye tumors
Choroidal melanoma in adults
Retinoblastoma in children
Breast cancer
Bowel cancer
Colon cancer
Small intestine cancer
Rectal cancer
Anal cancer
Neuroendocrine tumors
Gynecological tumors
Cervical cancer
Uterine cancer
Ovarian cancer
Vulvar cancer
Vaginal cancer
Skin cancer
Malignant melanoma
Basal cell carcinoma
Cancroid
Merkel-cell carcinoma
Skin lymphoma
Skin metastases
Tumors of the brain and spinal cord
Glioblastomas
Astrocytomas
Ependymomas
CNS lymphoma
Medulloblastomas
Neuromas
Meningiomas
Pituitary adenomas
Craniopharyngiomas
Metastases
Bone and soft tissue tumors
Sarcomas
Head and neck tumors
Mouth cancer
Tumors with localization in the nose or paranasal sinuses
Lower jaw tumors
Pharyngeal cancer
Laryngeal cancer
Salivary gland cancer
Cancer of the liver and biliary tract
Leukemia, lymphoma, multiple myeloma
Lung cancer, including thymus cancer and pleural mesothelioma
Esophageal and stomach cancer
Metastases
Liver metastases
Peritoneal carcinomatosis
Brain metastases
Bone metastases
Lymph node metastases
Lung metastases
Skin metastases
Metastases of cancer of unknown primary
Adrenal cancer, neuroblastoma, pheochromocytoma
Neuroendocrine tumors with localization in the small and large intestines, pancreas, lung, stomach, cancer with unknown primary localization
Pancreatic cancer
Prostate cancer
Thyroid cancer
Urogenital tumors
Kidney cancer
Bladder cancer
Ureteral cancer
Testicular cancer
Penile cancer
Cancer in children and adolescents
Leukemia
Lymphomas
Sarcomas
Brain tumors
Eye tumors
Neuroblastomas
Other oncological diseases
Curriculum vitae
2015 Appointed as Professor in Oncology (W3) and Head of the Charite Comprehensive Cancer Center.
2013 - 2015 Acting Director of the Charite Comprehensive Cancer Center, Berlin.
2008 - 2013 Deputy Director of the Charite Comprehensive Cancer Center.
2003 - 2015 C3 Professor in Clinical and Molecular Oncological Immunology, Charite University Hospital Berlin.
1998 Visiting Professor in Internal Medicine, Free University of Berlin.
1997 - 2013 Deputy Head, Department of Hematology, Oncology and Oncological Immunology, Charite University Hospital Berlin.
1993 Qualification in Hematology and Internal Oncology.
1990 - 1997 Senior Physician, Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg.
1990 Medical Specialist in Internal Medicine.
1986 Scientific Internship at the National Cancer Institute, Bethesda, USA, Surgery, Department of Immunotherapy.
1983 - 1990 Fellow, Heidelberg University, University Hospital Heidelberg.
1984 PhD defense, Institute of Pathophysiology and Sports Medicine, Heidelberg University.
1977 - 1983 Study of Medicine at the University of Mainz, Heidelberg University, University of Lexington (USA).
Activities in the Scientific Societies
1999 - 2006 Board Member of the Working Group on Internal Oncology.
2003 - 2005 Working Group on Melanoma Treatment (EORTC), Secretary (2001 - 2003), Board Member (2003 - 2005).
2003 - 2006 International Society for Biological Cancer Therapy (iSBTc), Vice President (2003 - 2005), President (2005 - 2006).
2006 - 2009 National Representative of Germany in the European Society for Medical Oncology (ESMO).
Photo of the doctor: (c) Charité – Universitätsmedizin Berlin
About hospital
According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities!
The hospital in Germany provides modern diagnostics and treatment of patients, as well as the training of practicing physicians and scientists. More than half of all German Nobel Prize winners in the field of medicine and physiology, such as Emil von Behring, Robert Koch and Paul Ehrlich, trained and worked in the hospital. The structure of the medical complex includes over 100 specialized departments and institutes, which allows the doctors to guarantee their patients' services in all the existing medical fields. The hospital in Germany has outstanding experience in treating particularly complex clinical cases.
The hospital annually diagnoses and treats more than 152,693 inpatients and about 692,920 outpatients. It also has a huge medical team consisting of 4,225 scientists and doctors and and more than 4,500 nursing staff members who provide top-class medical treatment in Germany. The key task for all specialists of the medical facility is restoring the patient's health or preserving in critical cases. At the same time, the hospital offers a friendly atmosphere, and each patient feels care, respect and sympathy.
The excellent technical medical equipment, highly skilled personnel, availability of innovative diagnostic and treatment techniques, and high ethical standards form a solid foundation for successful clinical and scientific activities. Thus, the hospital is a leading provider of high-quality treatment in Germany.
Photo: (с) depositphotos
Accommodation in hospital
Patients rooms
The patients of the Charite University Hospital Berlin live in comfortable rooms made of modern design. Each room is equipped with an ensuite bathroom with a toilet and a shower. The standard room furnishing includes an automatically adjustable bed, a bedside table, a wardrobe for storing clothes, a table and chairs for receiving visitors, and a TV. If desired, Wi-Fi access can be provided. The hospital also offers enhanced-comfort rooms.
Meals and Menus
The patient and his accompanying person have a daily choice of three menus. If for any reason, you do not like the food, you will be offered an individual menu. Please inform the medical staff about your dietary preferences before the treatment.
Further details
Standard rooms include:
Toilet
Shower
Wi-Fi
TV
Religion
Religious services are available upon request.
Accompanying person
During the inpatient program, an accompanying person may stay with you in a patient room or at the hotel of your choice.
Hotel
During the outpatient program, you can live at a hotel of your choice. Managers will help you to choose the most suitable options.
The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET / CT, angiography, myelography, biopsy and other examinations. Treatment with medications, endoscopic and robotic operations, stereotaxic interventions is carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.
These are oncological diseases, benign neoplasms of the brain and spinal cord, heart valve defects, diabetes mellitus and its complications, joint diseases and other pathologies.