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Charite University Hospital Berlin

Berlin, Germany


Spinal muscular atrophy diagnosis and conservative treatment (program ID: 302458)


Matthias Endres

Head Physician
Prof. Dr. med.

Matthias Endres

Department of Neurology

Specialized in: neurology
Curriculum vitae keyboard_arrow_down
  • Since 2005 W2 Professorship for Neurology at the Charité – Universitätsmedizin Berlin
  • Since 2004  Attending Physician at the Department of Neurology, Charité (Stroke Unit and Intensive Care Unit)
  • 2003 - 2005 Heisenberg Fellow, DFG
  • 1998 - 2003  Neurological Resident, Department of Neurology, Charité (Advisor: Prof. Einhäupl)
  • 1998 - 2004 Group Leader, ‘Cerebral Ischemia’ at the Department of Experimental Neurology Charité (Prof. Dirnagl)
  • 1996 - 1998 Fellow at Neuroscience Center, Massasuchetts General Hospital, Harvard Medical School, Boston (Advisor: Prof. Moskowitz)
  • 1994 - 1996 Neurological Resident, Medical University of Lübeck (Advisor: Prof. Kömpf)
  • 1988 - 1994 Studies in medicine at medical schools in Bochum, New York, Toronto, Hamburg

Research fields

  • Preventive vascular mechanisms (endothelial function, physical activity, harmacology)
  • Mechanisms of cell death (cell cycle activation, DNA damage and repair, apoptosis)
  • Regeneration and functional outcome (cellular plasticity, neurogenesis)

Clinical studies (stroke unit, telemedicine)

About the department keyboard_arrow_down

The Department of Neurology at the University Hospital Charite provides treatment of the full range of neurological disorders. Located at the Charité Campuses Mitte, Vichow-Klinikum and Benjamin Franklin, the department is headed by Prof. Dr. med. Matthias Endres.

The department specializes in the treatment of stroke, hemorrhages, blood clots, meningoencephalitis and autoimmune diseases of the central nervous system. In addition, the department offers ultrasound  diagnosis and ultrasound therapy.

The department has 160 beds, 20 of which belong to the Stroke Units and 14 belong to the Intensive Care Units.The activities of the whole highly dedicated team of neurologists and neuroscientists of the department focus on the studying and treatment of diseases of the nervous system.

The Department of Neurology has the most advanced technology and equipment:

  • Routine monitoring and advanced intensive care monitoring
  • Neurophysiological monitoring
  • State-of-the-art CT & MRI
  • Bone marrow transplant
  • Physiotherapy
  • Сerebral microdialysis

According to the Focus magazine rating of 2017, the Department of Neurology at the University Hospital Charite ranks among the top German departments specializing in the treatment of multiple sclerosis, Alzheimer’s disease and Parkinson’s disease!

Program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • physical examination
  • neurological examination:
    • somatosensory evoked potentials
    • reflexes
    • muscle strength
    • muscle tone
    • senses of touch and sight
    • coordination
    • balance
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • enzyme tests
    • inflammation indicators
    • BSG
    • creatine kinase (CK)
    • immunoelectrophoresis
    • vitamin B12, vitamin D
    • thyroid parameters
    • parathormone
    • genetic testing for bi-allelic deletion
      of exon 7 of the SMN1 gene
  • electromyography (EMG)
  • brain and neck CT/ MRI
  • muscle biopsy if indicated
  • X-ray of the chest
  • CSF puncture with nervous water examination
  • cerebrovascular doppler ultrasound
  • symptomatic treatment 
  • control examinations
  • the cost of essential medicines and materials
  • nursing services
  • full hospital accommodation
  • developing of further guidance
Type of program :
Expected duration of the program:

The program includes:


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