Treatment of breast cancer with embolization or chemoembolization (program ID: 689051)
Charite University Hospital Berlin
Bernd HammSpecialized in: diagnostic and interventional radiology
Department of Adult and Pediatric Diagnostic, Interventional Radiology
- Initial presentation in the hospital
- Clinical history taking
- Review of available medical records
- Physical examination
- Laboratory tests:
- Complete blood count
- General urine analysis
- Biochemical analysis of blood
- Tumor markers
- Inflammation indicators (CRP, ESR)
- Ultrasound scan
- CT scan / MRI
- Preoperative care
- Embolization or chemoembolization, 2 procedures
- Symptomatic treatment
- Cost of essential medicines
- Nursing services
- Elaboration of further recommendations
How program is carried out
During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI. This will allow the doctor to determine which vessels are feeding the tumor and its metastases, as well as determine how well you will tolerate the procedure.
Chemoembolization begins with local anesthesia and catheterization of the femoral artery. The thin catheter is inserted through a few centimeters long incision of the blood vessel. The doctor gradually moves the catheter to the vessel feeding the primary tumor or its metastases. The procedure is carried out under visual control, an angiographic device is used for this. The vascular bed and the position of the catheter in it are displayed on the screen of the angiograph.
When the catheter reaches a suspected artery, a contrast agent is injected through it. Due to the introduction of the contrast agent, the doctor clearly sees the smallest vessels of the tumor and the surrounding healthy tissues on the screen of the angiograph. After that, he injects emboli into the tumor vessels through the same catheter.
Emboli are the spirals or the liquid microspheres. The type of embolus is selected individually, taking into account the diameter of the target vessel. When carrying out chemoembolization, a solution of a chemotherapy drug is additionally injected into the tumor vessel. Due to the subsequent closure of the vessel lumen with an embolus, the chemotherapy drug influences the tumor for a long time. In addition, the drug does not enter the systemic circulation, which allows doctors to use high doses of chemotherapeutic agents without the development of serious side effects. Chemoembolization leads to the destruction of the tumor or slowing down its progression.
After that, the catheter is removed from the artery. The doctor puts a vascular suture on the femoral artery and closes it with a sterile dressing. During chemoembolization, you will be awake. General anesthesia is not used, which significantly reduces the risks of the procedure and allows performing it on an outpatient basis, avoiding long hospital stay.
After the first procedure, you will stay under the supervision of an interventional oncologist and general practitioner. If necessary, you will receive symptomatic treatment. As a rule, a second chemoembolization procedure is performed in 3-5 days after the first one in order to consolidate the therapeutic effect. After that, you will receive recommendations for further follow-up and treatment.
- Medical records
- MRI/CT scan (not older than 3 months)
- Biopsy results (if available)
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About the department
The Department of Adult and Pediatric Diagnostic, Interventional Radiology at the Charite University Hospital Berlin offers the full range of medical services in these fields. In order to ensure the most accurate and reliable diagnostics, the department has state-of-the-art systems for CT, MRI, PET, ultrasound and X-ray examinations, as well as PET-CT and SPECT-CT hybrid examinations. The department specializes in interventional radiology, namely, imaging-guided therapy. It performs all vascular (for example, vascular recanalization) and non-vascular imaging-guided interventions (for example, tumor ablation). The department is one of the largest and leading medical facilities of this kind in Europe. The Chief Physician of the department is Prof. Dr. med. Bernd Hamm.
In the field of diagnostic radiology, all modern imaging examinations are carried out. The great advantage of the department is the availability of specially adapted diagnostic systems for the diagnostics of children, for example, ultrasound, X-ray, CT, etc. The cutting-edge medical equipment guarantees an optimal radiation protection, so the diagnostic tests do not harm the health of either children or adults.
It should be noted that the department is a recognized Center for Minimally Invasive Surgery. In the case of minimally invasive interventions, such radiological methods as X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) serve as imaging-guided tools. This ensures accurate, targeted surgery. In most cases, local anesthesia is used. An exception is the treatment of osteoid osteoma, which is performed under general anesthesia. Minimally invasive procedures include tissue sampling for diagnostic tests, blockade of nerve endings during pain therapy, use of laser techniques for the treatment of tumors and spinal disc herniation, restoration of blood vessel patency in thrombosis, arrest of arterial hemorrhages, blockade of tumor blood supply, etc.
The department's specialists always prefer an individual approach to treatment. Many minimally invasive techniques have been developed or improved by the department's doctors, which guarantees the highest treatment quality. The department annually performs more than 2,000 minimally invasive interventions (from tissue sampling to tumor treatment). Prior to any type of treatment, the department's doctors discuss in detail the therapeutic possibilities with the patient, including therapy risks and alternative treatment methods.
The service range of the department includes:
- Diagnostic radiology
- Magnetic resonance imaging (MRI)
- MRI of organs and anatomical structures of the neck (for example, salivary glands, larynx, trachea)
- Breast MRI
- Abdominal MRI
- Pelvic MRI
- Musculoskeletal MRI
- Vascular MRI (MR angiography)
- MRI of the nervous system
- Ultrasound examinations
- Radiodiagnostics in inflammatory rheumatic and degenerative joint diseases
- Breast imaging
- Cancer screening
- Breast MRI
- Vacuum-assisted breast biopsy
- Breast ultrasound examination
- MRI diagnostics of the pelvic organs in women
- Prostate imaging
- Imaging examinations in children (ultrasound, X-ray, CT, MRI)
- Magnetic resonance imaging (MRI)
- Interventional radiology
- Treatment of vascular diseases
- Dialysis access formation
- Implantation of central venous port systems
- Transjugular intrahepatic portosystemic shunting
- Treatment of peripheral arterial occlusive disease
- CT-guided puncture
- CT-guided drainage
- Prostate cancer treatment
- Focal therapy
- Irreversible electroporation
- Treatment of back pains
- Conservative methods (drug therapy, physiotherapy, etc.)
- X-ray-, CT- and MRI-guided infiltration of nerve roots, vertebral joints, sacroiliac joints and sympathetic trunk
- Periradicular injection therapy
- Injection therapy of facet and sacroiliac joints
- Treatment of uterine fibroids
- Uterine fibroid embolization
- Treatment of vascular diseases
- Other medical services
- 1972 - 1978 Study of Human Medicine at the Free University of Berlin.
- 1978 - 1986 Scientific Assistant at the Institute of Pathology, Department of Radiation Therapy, Department of Radiology and Nuclear Medicine at the Steglitz Clinic of the Free University of Berlin.
- 07.07.1982 Doctorate at the Faculty of Medicine of the Free University of Berlin, "magna cum laude".
- 16.05.1986 Specialist examination and recognition as a Medical Specialist in Radiology.
- 02.1989 Habilitation and Venia legendi by the Faculty of Medicine at the Free University of Berlin in Radiology.
- 1990 - 1993 Head of the Department of Radiology and Nuclear Medicine at the Steglitz Clinic of the Free University of Berlin.
- 04.1993 Appointment as C3 Professor for Clinical Radiology at the Free University of Berlin.
- 1993 Call for the C4 Professorship for Diagnostic Radiology at the Medical University of Essen (primo loco).
- 1994 Received and accepted the call for C4 Professorship for X-ray Diagnostics at the Charité, Faculty of Medicine at the Humboldt University of Berlin (primo loco).
- 1998 Received the call for C4 Professorship for Diagnostic Radiology at the Goethe University Frankfurt (primo loco).
- 01.2006 - 04.2009 Acting Head of the Department of Nuclear Medicine at the Charité.
- Since 2006 Head of the CharitéCenter 6 (Diagnostic and Interventional Radiology/Nuclear Medicine/Medical Physics) and taking responsibility for budget of the mentioned areas, Charité.
- 10.2006 Appointment as the Head of the Department of Clinical Radiology and Director of the merged Radiology at the Charité – Campus Mitte and Campus Virchow Clinic.
- Since 2004/2006 Director of four Medical Care Centers (MVZ) for Radiology and Nuclear Medicine at the Charité, as well as a Research and Clinical Director of three Centers for Imaging Diagnostics in Berlin.
- 10.2010 Appointment as the Head of the Department of Radiology and Head of three merged Departments of Radiology at the Charité – Campus Mitte, Campus Virchow and Campus Benjamin Franklin.
- 2012 Honorary Professorship at the China-Japan Friendship Hospitals, Peking.
Photo of the doctor: (c) Charité – Universitätsmedizin Berlin