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University Hospital Erlangen

location_on Erlangen, Germany
9.1/10 from 51 Votes

Department of Nephrology (289960)

Mario Schiffer

Prof. Dr. med.

Mario Schiffer

Specialized in: nephrology

About the Department of Nephrology at University Hospital Erlangen

According to Focus magazine, the Department of Nephrology at the University Hospital Erlangen ranks among the best specialized Nephrology Centers in Germany!

The department provides both diagnostics and treatment of all congenital and acquired kidney diseases, arterial hypertension caused by kidney lesions, as well as their complications. Particular attention is paid to kidney failure, for the treatment of which doctors use all types of renal replacement therapy up to kidney transplant (in cooperation with specialized surgeons). The department's medical team offers a unique experience in care for patients before and after kidney transplant. The preoperative phase includes a comprehensive assessment of surgical risks and expected outcomes, while therapeutic measures after the transplant surgery are aimed at preventing rejection of the transplanted kidney. The medical facility has well-equipped diagnostic and therapeutic rooms, including an advanced Renal Replacement Therapy Unit specializing in dialysis. Patients most often undergo hemodialysis and peritoneal dialysis. The department's doctors provide patients with high-quality medical services focused on meeting their individual needs and wishes. The Chief Physician of the department is Prof. Dr. med. Mario Schiffer.

The department's specialists offer optimal treatment for all congenital and acquired kidney diseases. With the help of blood tests and urinalysis, ultrasound and X-ray scans, diagnostic imaging of blood vessels and kidney biopsy, the department's doctors conduct accurate diagnostics of nephrologic disease and determine its stage. The treatment involves the use of modern medical protocols, which allow achieving complete cure or at least remission of the disease. The department can boast of its special experience in the treatment of patients with concomitant diseases, for example, vascular stenosis. In such cases, doctors from related specialties are involved in the therapeutic process.

The department has an impeccable reputation in the treatment of acute and chronic kidney failure. In addition to all types of renal replacement therapy, the department uses other extracorporeal treatment methods, for example, extracorporeal membrane oxygenation (ECMO), implantation of artificial heart ventricles (LVAD, RVAD), Prometheus® therapy, etc. Special attention is paid to transplant medicine. The ​​responsibility of the department's nephrologists includes preparation for surgery and postoperative care after kidney transplant. Kidney transplant procedures are performed cooperatively by specialists in general surgery, urology and vascular surgery. The Transplant Center of the university hospital performs more than 70 kidney transplants every year, so all therapeutic processes are perfectly organized and patients can be sure that they will get the best result.

The department's doctors have extensive clinical experience and professional skills in the treatment of genetically determined nephrological diseases of unknown origin, genetic neoplastic diseases of the kidneys (for example, Von Hippel-Lindau syndrome, rare types of polycythemia), congenital kidney pathologies (for example, tubulointerstitial nephritis, thrombotic microangiopathy), glomerulopathies caused by lysosomal storage diseases, systemic diseases with kidney lesions, polycystic kidney disease and other pathologies. The course of treatment is usually based on the intake of modern medications for kidney function normalization.

In addition, the specialists of the medical facility provide all modern medical services to patients with arterial hypertension caused by kidney pathology. The ​​competence of doctors includes the treatment of rare forms of arterial hypertension. The department also admits patients with electrolyte disorders. To correct high blood pressure, specialists select the optimal complex of medicines for each patient. The department's doctors often recommend the patients to reconsider their lifestyle – lose weight, have a healthy diet, stop drinking alcohol and give up smoking, avoid stressful situations and a sedentary lifestyle.

The department's range of medical services includes:

  • Diagnostics and treatment of acute and chronic kidney failure
  • Diagnostics and treatment of congenital kidney diseases
    • Autosomal dominant polycystic kidney disease
    • Autosomal dominant tubulointerstitial kidney disease
    • Von Hippel-Lindau syndrome
    • Alport syndrome
    • Hereditary nephropathy
    • Fabry disease
    • Tuberous sclerosis
    • Renal tubular acidosis
  • Diagnostics and treatment of glomerulonephritis
  • Diagnostics and treatment of polycystic kidney disease
  • Diagnostics and treatment of interstitial nephritis
  • Diagnostics and treatment of pathological kidney lesions in systemic diseases (for example, in vasculitis, autoimmune diseases, cancers, sarcoidosis, diabetes mellitus, etc.)
  • Diagnostics and treatment of arterial hypertension
  • Diagnostics and treatment of electrolyte disorders
  • Diagnostics and treatment of other diseases

The department's therapeutic options include:

  • Drug therapy for kidney diseases and arterial hypertension
  • Renal replacement therapy
    • Hemodialysis
    • Peritoneal dialysis
    • Hemodiafiltration
    • Hemofiltration
    • Dialysis with the Genius system
    • Continuous venovenous hemofiltration (CVVH)
    • Continuous venovenous hemodialysis (CVVHD)
  • Blood purification procedures
    • Hemoperfusion
    • Plasmapheresis
    • Immunoadsorption
    • Low-density lipoprotein apheresis
  • Emergency medical care for critical conditions
  • Preparation for kidney transplant surgery and follow-up care with transplant rejection prevention
  • Other treatment methods

Curriculum vitae of Prof. Dr. med. Mario Schiffer

Education and Professional Career

  • 1992 - 1999 Study of Human Medicine at the Free University of Berlin and King’s College, London.
  • 1999 - 2000 Beginning of the internship in Internal Medicine, special focus on Nephrology and Hypertensiology, Friedrich Alexander University Erlangen-Nuremberg.
  • 2000 - 2004 Research Fellow, Department of Nephrology, Albert Einstein College of Medicine, New York.
  • 2004 - 2008 Assistant Physician, Department of Nephrology and Hypertensiology, Hannover Medical School.
  • 2008 Board certification in Internal Medicine, habilitation in Internal Medicine, Senior Physician.
  • Since 2011 W3 Professor specializing in Nephrology and Transplantation Nephrology, Deputy Head of the department.
  • Since 01.09.2018 Head of the Department of Nephrology at the University Hospital Erlangen.

Scientific Career

  • 1994 - 1996 Doctoral thesis at the Institute of Molecular Biology and Biochemistry, Free University of Berlin.
  • 1996 Molecular Biology Training at the Washington University School of Medicine, Department of Pediatrics, Section of Rheumatology and Immunology, St. Louis, USA.
  • 1998 Exchange Student (one academic year) in the Biomedical Sciences Exchange Program (BMEP), Albert Einstein College of Medicine of Yeshiva University, Department of Internal Medicine, Section of Nephrology, New York, USA.
  • 2000 - 2004 Research Fellow, Albert Einstein College of Medicine, Bronx and Mt. Sinai School of Medicine, New York, USA, funded by the German Research Foundation (DFG), Juvenile Diabetes Research Foundation and National Kidney Foundation.
  • Since 10.2004 Head of the Emmy Noether Young Research Group of the German Research Foundation (DFG), Hannover Medical School.
  • Since 01.2008 Project Leader of the SFB 566 Cytokines and Cytokine Signaling, Hannover Medical School.
  • Since 07.2008 Project Leader in IFB-Tx: "Renal Comorbidity After Solid Organ Transplantation-RECAST".

Clinical Interests

  • Treatment of proteinuria.
  • Patient care after kidney transplantation.

Research Interests

  • Study of the causes of the development of proteinuria.
  • Study of rare kidney diseases caused by damage to the glomerular filter.
  • Study of concomitant diseases of the kidneys and other large organs after kidney transplantation.
  • Study of the role of B cells in transplant rejection.

Awards, Prizes and Honors

  • Franz Volhard Prize.
  • Jan Brod Prize.
  • Nils Alwall Prize of the German Society of Nephrology.

Memberships in Professional Societies

  • German Society of Internal Medicine.
  • German Society of Nephrology.
  • German Transplantation Society (DTG).
  • European Renal Association-European Dialysis Transplant Association (ERA-EDTA).
  • American Society of Nephrology (ASN).
  • American Society of Transplantation (AST).

Photo of the doctor: (c) Universitätsklinikum Erlangen

Department of Nephrology.
University Hospital Erlangen:

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