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University Hospital Frankfurt am Main

Department of Cardiology and Angiology (26146)

Andreas Zeiher

Prof. Dr. med.

Andreas Zeiher

Specialized in: cardiology, angiology

About the department

According to the prestigious Focus magazine, the Department of Cardiology and Angiology at the University Hospital Frankfurt am Main ranks among the top German medical facilities specializing in the treatment of heart diseases!

The department offers the full range of modern diagnostic and conservative therapeutic techniques for patients with cardiovascular diseases. The department houses a General Cardiology Outpatient Clinic, high-tech Cardiac Catheterization Laboratory and Emergency Cardiac Care Unit. The medical facility is also certified as an Interdisciplinary Center for Heart Failure and a Center for Transcatheter Aortic Valve Implantation. All this creates excellent conditions for the provision of highly professional and effective medical care. The department is headed by Prof. Dr. med. Andreas Zeiher.

To make an accurate diagnostics and develop an optimal treatment strategy, the department's cardiologists carry out modern diagnostic examinations. An important structural object of the department is the Cardiac Catheterization Laboratory. It offers all methods of invasive diagnostics of ischemic heart disease, pathologies of large blood vessels, myocardial diseases, heart valves, pulmonary circulatory disorders, etc. In addition, the doctors of the laboratory specialize in unique examinations, which are available only in the advanced medical centers in Europe, for example, intravascular ultrasound (IVUS), optical coherence tomography (OCT), intracoronary Doppler flow velocity and pressure measurements for the assessment of endothelial function, etc.

If necessary, doctors can perform medical invasive procedures, in particular, coronary artery interventions. An important focus of the Cardiac Catheterization Laboratory is the treatment of structural heart diseases, such as atrial septal defect and ventricular septal defect. Also, the department's doctors have exceptional experience in the field of catheter treatment of aortic stenosis and mitral valve insufficiency (MitraClip technique, mitral valve annuloplasty).

Of particular interest is the diagnostics and treatment of cardiac arrhythmias (electrophysiology). In order to eliminate these disorders, the doctors use the very latest techniques, such as cardiac resynchronization therapy, implantation of pacemakers, defibrillators, event recorders, cardiac contractility modulation systems.

The department's angiologists specialize in the diagnostics and treatment of patients with vascular diseases. All methods of non-invasive and invasive diagnostics of vascular pathologies are available here. One of the priority clinical interests is the treatment of patients with peripheral arterial occlusive disease.

The service range of the department includes:

Cardiology

  • Diagnostic options
    • Non-invasive examinations
      • Resting and stress ECG
      • Spiroergometry
      • 24-hour Holter monitoring
      • Diagnostics using an event recorder
      • 24-hour blood pressure monitoring
      • Orthostatic test (tilt test)
      • Transthoracic echocardiography
      • Transesophageal echocardiography
      • Stress echocardiography
      • Magnetic resonance imaging
      • 6-slice CT scanner (with two X-ray sources)
    • Invasive examinations
      • Heart catheter diagnostics
      • Left heart catheterization
      • Right heart catheterization
      • Intravascular ultrasound (IVUS)
      • Fractional flow reserve measurement
      • Endothelial function examinations
      • Myocardial biopsy
      • Electrophysiological examinations
      • Carto 3D mapping technique
      • Event recorder implantation
  • Therapeutic options
    • Invasive treatment of cardiac pathologies
      • Percutaneous transluminal coronary angioplasty (PTCA)
      • Coronary stent implantation, including drug-coated stent implantation
      • Minimally-invasive valve replacement, MitraClip technique in mitral valve insufficiency
      • Left atrial appendage closure (left atrial appendage occluder)
      • Closure of atrial septal defects, interventricular septal defects, open foramen ovale
      • Stem cell therapy in acute infarction and coronary artery disease
      • High-frequency and cryoballoon techniques for the treatment of arrhythmias, including atrial fibrillation
      • Implantation of pacemakers and defibrillators
      • Cardiac resynchronization therapy device implantation
      • Cardiac contractility modulation in heart failure
    • Conservative treatment of cardiac pathologies
      • All modern pharmacological products, drugs and intensive therapy methods
  • Other diagnostic and therapeutic options

Angiology

  • Diagnostic options
    • Duplex ultrasonography and continuous-wave Doppler of all blood vessels
    • Determination of ankle-brachial pressure index
    • Oscillography
    • Treadmill ergometer
    • Microcirculation assessment
    • Percutaneous measurement of oxygen partial pressure
    • Capillary microscopy
    • Digital subtraction angiography
  • Therapeutic options (minimally invasive techniques)
    • Percutaneous transluminal coronary angioplasty (PTCA)
    • Balloon angioplasty
    • Angioplasty using special drug-coated stent implantation
    • Implantation of vascular endoprostheses
    • Recanalization in prolonged and chronic occlusions
    • Local intra-arterial thrombolysis
    • Therapy using autologous stem cells in stage III-IV peripheral arterial occlusive disease according to Fontaine classification
  • Other diagnostic and therapeutic methods

Curriculum vitae

Education

  • 1974 - 1981 Medical School, University of Freiburg.
  • 1979 - 1981 Doctoral thesis. 
  • May 1981 Licence to practice medicine.

Professional Career

  • 11.1981 - 03.1983 Resident, Department of Internal Medicine, Division of Cardiology, University Hospital Freiburg.
  • 04.1983 - 02.1986 Clinical Fellow, Department of Internal Medicine, Division of Cardiology, University Hospital Freiburg.
  • 03.1986 - 12.1987 Research Fellowship of the German Research Foundation (DFG) at Cedars-Sinai Medical Centre, School of Medicine, University of California, Los Angeles, CA, USA.
  • 01.1988 - 09.1990 Clinical Fellow, Department of Internal Medicine, Division of Cardiology, University Hospital Freiburg.
  • 01.1990 Associate Professor.
  • 10.1990 - 05.1995 Director of the Section for Interventional Cardiology, Department of Internal Medicine, Division of Cardiology, University Hospital Freiburg.
  • Since May 1995 Head of the Department of Cardiology and Angiology at the University Hospital Frankfurt am Main. 
  • 2002 - 2004 Chairman, Working Group on Interventional Cardiology, European Society of Cardiology.
  • 2001 - 2006 Vice Chairman, Board of Directors at the University of Frankfurt.

Prizes and Honours

  • 1991 Rudolf Thauer Award of the German Society for Heart and Circulation Research.
  • 1995 Franz Loogen Prize of the Society of Heart and Circulation Research, Essen.
  • 2001 Fritz Acker Prize, Fritz Acker Foundation, Bad Homburg.
  • 2004 CARIM Lecture, University of Maastricht, the Netherlands.
  • 2005 HJC Swan Professorship, Cedars-Sinai Medical Center, University of California, Los Angeles.
  • 2006 Princess Lilian Professorship, Belgian Society of Cardiology, University of Brussels.
  • 2007 Ernst Jung Prize.
  • 2009 Paul Morawitz Prize of the German Society of Cardiology.
  • 2009 Princesses’ Lecture, Victor Chang Cardiac Research Institute, Sydney.
  • 2010 Award of the International Society for Cardiovascular Translational Research.
  • 2010 Stanley Davidson Lecture, Royal College of Physicians of Edinburgh, Scotland.
  • 2012 Krakoff International Lecture, Brigham and Women’s Hospital, Boston.

Research Interests

  • Basic and clinical aspects of vascular biology and atherosclerosis.
  • Role of stem and progenitor cells for endogenous cardiovascular repair, as well as their therapeutic application for regenerating cardiovascular function.
  • Use of biomarkers for risk prediction and therapeutic stratification of patients with acute coronary syndromes.

Memberships in Professional Societies

  • Fellow of the European Society of Cardiology.
  • Past Chairman of the Working Group on Interventional Cardiology of the European Society of Cardiology.
  • Co-Chairman of the Excellence Cluster Cardio-Pulmonary System (ECCPS) of the German Research Foundation (DFG).

Department of Cardiology and Angiology.
University Hospital Frankfurt am Main:

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