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University Hospital Frankfurt am Main

Department of Pediatric Immunology and Stem Cell Transplantation (304075)

Peter Bader

Prof. Dr. med.

Peter Bader

Specialized in: pediatric immunology, stem cell transplantation

About the department

The Department of Pediatric Immunology and Stem Cell Transplantation at the University Hospital Frankfurt am Main offers the full range of medical services in these fields and treats children, adolescents and young people with malignant and benign diseases. Special attention is paid to haploidentical stem cell transplantation and CAR T-cell therapy. The department performs more than 60 stem cell transplantations every year. The department also treats congenital and acquired immunodeficiency conditions. The Chief Physician of the department is Prof. Dr. med. Peter Bader.

The department is one of the largest Pediatric Transplant Centers in Germany. Particular attention is paid to haploidentical stem cell transplantation. This method makes it possible to use parents as donors for transplantation. Thus, stem cell transplantation becomes possible for each child.

In the field of immunology, the department treats immunodeficiencies of all types and degrees of severity. A special Immunology Laboratory serves for the conduction of all modern examinations, which are necessary for making an accurate diagnosis. The young patients with complex symptoms are provided with regular interdisciplinary boards with the specialists in pediatric hematology, gastroenterology and endocrinology. In addition, the department is an active participant in national and international clinical trials aimed at the development of new effective treatment methods. Thus, the patients have access to all therapeutic options.

The department specializes in the treatment of the following diseases:

  • Malignant diseases
    • Blood diseases
      • Acute lymphocytic leukemia
      • Acute myeloid leukemia
      • Chronic myeloid leukemia
      • Juvenile myelomonocytic leukemia
      • Juvenile myelomonocytic leukemia
    • Lymphomas
      • Hodgkin's lymphoma
      • Non-Hodgkin's lymphoma
    • Solid tumors
      • Soft tissue sarcomas
      • Ewing's sarcoma
      • Neuroblastoma
      • Hepatoblastoma
      • Primitive neuroectodermal tumor
      • Synovial sarcoma
      • Nephroblastoma
      • Germ cell tumors
    • Brain tumors
  • Benign diseases
    • Impaired hematopoiesis
      • Congenital and acquired anemias
        • Severe aplastic anemia
        • Tallassemia
        • Sickle cell anemia
        • Diamond–Blackfan anemia
      • Congenital and acquired thrombocytopenias
        • Amegakaryocytic thrombocytopenia
        • Evans syndrome
      • Myelopoiesis disorders
        • Familial hemophagocytic lymphohistiocytosis
        • Histiocytosis
    • Diseases of the immune system 
      • Severe combined immunodeficiency
      • Wiskott-Aldrich syndrome
      • Septic granulomatosis
      • Kostmann syndrome
      • Griscelli Syndrome
    • Metabolic and autoimmune diseases
      • Farber's disease
      • Mucopolysaccharidosis
      • Osteopetrosis ("marble disease")
      • Systemic lupus erythematosus
      • Rheumatoid arthritis
      • Metachromatic leukodystrophy
      • Adrenoleukodystrophy
  • Other malignant and benign diseases

The therapeutic options of the department include:

  • Stem cell transplantation
    • Autologous stem cell transplantation
    • Allogeneic stem cell transplantation
    • Haploidentical stem cell transplantation
  • Immune and cell therapy
    • CAR T-cell therapy
    • Cytokine-induced killer cell (CIK) therapy
    • Mesenchymal stromal cell therapy
  • Other treatment methods

Curriculum vitae

Professional Сareer

  • 1986 - 1993 Study of Human Medicine, University of Tuebingen.
  • 1993 Doctorate.
  • 1993 - 1994 Intern, Department of Pediatric and Adolescent Medicine, University Hospital Tuebingen.
  • 1995 - 2000 Training for board certification in Pediatrics.
  • 2001 - 2004 Senior Physician, Section of General Pediatrics, Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Hospital Tuebingen.
  • 2001 Habilitation and Venia legendi in Pediatrics.
  • Since 2004 Head of the Department of Pediatric Immunology and Stem Cell Transplantation at the University Hospital Frankfurt am Main.

Awards and Honors

  • 2000 Van Bekkum Award.
  • 2003 BMT Nature Publishing Prize, Annual Meeting of the European Society for Blood and Marrow Transplantation.
  • 2004 Kind-Philipp Award.
  • 2007 BMT Nature Publishing Prize, Annual Meeting of the European Society for Blood and Marrow Transplantation.
  • 2006 Fritz Acker Award.
  • 2010 BMT Nature Publishing Prize, Annual Meeting of the European Society for Blood and Marrow Transplantation.
  • 2014 BMT Nature Publishing Prize, Annual Meeting of the European Society for Blood and Marrow Transplantation.

Therapeutic Specialization

  • Allogeneic stem cell transplantation in children and adolescents.
  • Immunotherapy and cell therapy.
  • Early detection of recurrence using molecular biological techniques after allogeneic stem cell transplantation.

Scientific Awards

  • Immunotherapy and cell therapy.
  • Early detection of recurrence after allogeneic stem cell transplantation (minimal residual disease control, MRD, and cell chimerism).

Membership in Professional Societies

  • American Society of Hematology (ASH).
  • Society for Pediatric Oncology and Hematology (GPOH).

Membership in Committees and Commissions

  • Board Member (Secretary) of the DAG-KBT (German Society for Blood and Marrow Transplantation).
  • Chairman of the Working Group on Pediatric Diseases of the European Society for Blood and Marrow Transplantation.

Department of Pediatric Immunology and Stem Cell Transplantation.
University Hospital Frankfurt am Main:

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