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Treatment of colon cancer with embolization or chemoembolization (program ID: 689343)

University Hospital Frankfurt am Main

location_on Frankfurt am Main, Germany
10/10 from 97 Votes
Specialized hospital
Thomas Vogl

Head Physician
Prof. Dr. med.

Thomas Vogl

Specialized in: adult and pediatric diagnostic, interventional radiology

Department of Adult and Pediatric Diagnostic, Interventional Radiology

Program includes:

  • Initial presentation in the hospital
  • Clinical history taking
  • Review of available medical records
  • Physical examination
  • Laboratory tests:
    • Complete blood count
    • General urine analysis
    • Biochemical analysis of blood
    • Tumor markers
    • Inflammation indicators (CRP, ESR)
    • Coagulogram
  • Ultrasound​ scan
  • CT scan / MRI
  • Preoperative care
  • Embolization or chemoembolization, 2 procedures
  • Symptomatic treatment
  • Cost of essential medicines
  • Nursing services
  • Elaboration of further recommendations

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI. This will allow the doctor to determine which vessels are feeding the tumor and its metastases, as well as determine how well you will tolerate the procedure.

Chemoembolization begins with local anesthesia and catheterization of the femoral artery. The thin catheter is inserted through a few centimeters long incision of the blood vessel. The doctor gradually moves the catheter to the vessel feeding the primary tumor or its metastases. The procedure is carried out under visual control, an angiographic device is used for this. The vascular bed and the position of the catheter in it are displayed on the screen of the angiograph.

When the catheter reaches a suspected artery, a contrast agent is injected through it. Due to the introduction of the contrast agent, the doctor clearly sees the smallest vessels of the tumor and the surrounding healthy tissues on the screen of the angiograph. After that, he injects emboli into the tumor vessels through the same catheter.

Emboli are the spirals or the liquid microspheres. The type of embolus is selected individually, taking into account the diameter of the target vessel. When carrying out chemoembolization, a solution of a chemotherapy drug is additionally injected into the tumor vessel. Due to the subsequent closure of the vessel lumen with an embolus, the chemotherapy drug influences the tumor for a long time. In addition, the drug does not enter the systemic circulation, which allows doctors to use high doses of chemotherapeutic agents without the development of serious side effects. Chemoembolization leads to the destruction of the tumor or slowing down its progression.

After that, the catheter is removed from the artery. The doctor puts a vascular suture on the femoral artery and closes it with a sterile dressing. During chemoembolization, you will be awake. General anesthesia is not used, which significantly reduces the risks of the procedure and allows performing it on an outpatient basis, avoiding long hospital stay.

After the first procedure, you will stay under the supervision of an interventional oncologist and general practitioner. If necessary, you will receive symptomatic treatment. As a rule, a second chemoembolization procedure is performed in 3-5 days after the first one in order to consolidate the therapeutic effect. After that, you will receive recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • Esophagogastroduodenoscopy (EGD), MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)
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About the department

The Department of Adult and Pediatric Diagnostic, Interventional Radiology at the University Hospital Frankfurt am Main provides the full range of services in these fields and specializes in conducting radiologic examinations, high-intensity focused ultrasound (HIFU) therapy, vascular, oncological, orthopedic and urologic interventions. The department includes specialized Sections for Gynecologic, Pediatric and Orthopedic Radiology. The Chief Physician of the department is Prof. Dr. med. Thomas Vogl.

In the field of diagnostics, the department offers the whole spectrum of modern diagnostic radiology, including CT and MRI diagnostics, X-ray diagnostics and ultrasound. To provide the fastest and most accurate diagnostics, the department has in its arsenal the very latest medical developments, for example, (128-slice) SOMATOM Definition AS scanner, SOMATOM Force Dual Source scanner, Siemens Somatom Definition AS Sliding mobile tomograph. These tomographs allow obtaining images of the highest quality with minimal radiation exposure to the patient.

In the field of interventional radiology, the department specializes in vascular, oncological, orthopedic interventions, as well as in prostate biopsy with an accuracy the nearest millimeter.

The department offers the full range of cancer interventions:

  • Laser-induced thermotherapy (LITT), which is a special minimally invasive thermotherapy for liver and lung tumors
  • Uterine fibroid embolization, which is a minimally invasive therapy for uterine myoma
  • Radiofrequency tumor ablation, which is a minimally invasive high-frequency thermoablation for liver and lung tumors
  • Selective internal radiation therapy with the use of SIR spheres, which is a minimally invasive radio-oncological treatment of liver tumors
  • Transpulmonary chemoembolization (TPCE), which is a minimally invasive and selective chemotherapy for lung tumors
  • Transarterial chemoperfusion (TACP), which is a minimally invasive percutaneous chemoperfusion for liver tumors
  • Prostate embolization in benign prostatic hyperplasia, which is a special minimally invasive therapy for benign prostatic hyperplasia
  • Other interventions

In addition, the department offers a wide range of minimally invasive vascular interventions. For example, excimer laser (ELA) angioplasty is successfully used in the treatment of peripheral arterial occlusive disease. It shows high rates of treatment effectiveness.

Also, the department offers special orthopedic interventions to treat herniated discs, osteoporosis and bone tumors. It uses a new minimally invasive method of treating herniated discs – ozone therapy. Its advantages include improving blood circulation and reducing inflammation, improving microcirculation and oxygen supply, etc. Another effective method is vertebroplasty/osteoplasty, which is used to reduce pain and stabilize the fractured vertebrae.

Another focus of the department is high-intensity focused ultrasound (HIFU) therapy. The department has one of the very first HIFU devices in Germany, which allows not only for tumor treatment, but also for its imaging. Focused ultrasound can be successfully used in the treatment of various benign and malignant tumors.

Indications for high intensity-focused ultrasound (HIFU) therapy:

  • Pancreatic tumors
  • Liver tumors
  • Kidney tumors
  • Breast fibroadenomas
  • Bone tumors
  • Uterine fibroids
  • Adenomyosis
  • Breast cancer

The main diagnostic and therapeutic focuses of the department are:

  • High-intensity focused ultrasound (HIFU) therapy
    • HIFU for liver tumors
    • HIFU for uterine myomas and adenomyosis
  • Diagnostic radiology
    • CT/MRI diagnostics
    • X-ray diagnostics
    • Ultrasound studies
  • Pediatric radiology (conventional X-ray studies, ultrasound, MRI)
  • Interventional radiology
    • Vascular interventions (for example, excimer laser angioplasty)
    • Cancer interventions
    • Orthopedic interventions
    • MRI-guided prostate biopsy
  • Cancer treatment
  • Interdisciplinary Center for Liver Diseases
  • Other diagnostic and therapeutic options

Curriculum vitae

  • 1976 - 1982 Study of Medicine at Ludwig Maximilian University of Munich.
  • 1980 Training at the Higher School of Medicine of the Hebrew University, Hadassah Hospital, Jerusalem.
  • 1980 - 1981 Assistant in the Department of Anatomy at the University of Munich.
  • 1982 Admission to medical practice.
  • Since 1983, Assistant Physician in the Department of Radiology, University of Munich.

Professional Experience

  • 1988 Internship at the Massachusetts General Hospital in Boston.
  • 1988 - 1990 Additional qualification in Nuclear Medicine.
  • 1989 Certified Radiologist specializing in Radiation Therapy.
  • 1990 Senior Physician of the Department of Radiology, University of Munich. Focuses: conventional X-ray diagnostics, ultrasound, CT, interventional radiology, establishment and management of the Department of MRI Diagnostics and Spectroscopy.
  • 1992 Specialized in Nuclear Medicine.
  • 1992 Specialized in In-Vitro Nuclear Diagnostics.
  • 1992 Appointment to the post of the Managing Senior Physician of the Department of Radiation Therapy at the Free University in Berlin, University Hospital Virchow.
  • 1992 (C3) University Professor at the Free University of Berlin, General Radiology.
  • Certified Neuroradiologist.
  • 1998 Invitation to hold a post of (C4) Professor in X-ray diagnostics, Frankfurt University.
  • 1998 Invitation accepted.
  • Since 1998, Chief Physician of the Department of Adult and Pediatric Diagnostic, Interventional Radiology at the University Hospital Frankfurt am Main.
  • 2005 Collaboration with the Friedrichsheim Orthopedic Clinic of the University of Frankfurt: Head of the Department of Radiology.

Main Clinical Focuses

  • Conventional X-ray diagnostics.
  • Traumatology.
  • Gastrointestinal radiology.
  • Interventional radiology.
  • Chemoembolization.
  • Angioplasty.
  • MRI diagnostics.

Main Research Focuses

  • MR-angiography.
  • In-vitro spectroscopy.
  • Development of contrast agents.
  • Interstitial laser therapy.
  • Hepatobiliary diagnostics.

 Photo of the doctor: (c) Universitätsklinikum Frankfurt 


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