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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC (639470) | University Hospital Oldenburg - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.<\/p>\n\n<p style=\"text-align:justify\"><strong>After the completion of the operation<\/strong>, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.<\/p>\n\n<p style=\"text-align:justify\">Finally, the attending physician will evaluate the results of&nbsp;<strong>control examinations<\/strong>, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.<\/p>\n<\/div><div class=\"program_required_documents mt-4\"><h4>Required documents<\/h4><ul>\n\t<li style=\"text-align: justify;\">Medical records<\/li>\n\t<li style=\"text-align: justify;\">MRI\/CT scan (not older than 3 months)<\/li>\n\t<li style=\"text-align: justify;\">Biopsy results (if available)<\/li>\n<\/ul>\n<\/div>","program_full_story_crm":"<ul>\n\t<li>Initial presentation in the clinic<\/li>\n\t<li>clinical history taking<\/li>\n\t<li>review of medical records<\/li>\n\t<li>physical examination<\/li>\n\t<li>laboratory tests:\n\t<ul>\n\t\t<li>complete blood count<\/li>\n\t\t<li>general urine analysis<\/li>\n\t\t<li>biochemical analysis of blood<\/li>\n\t\t<li>TSH-basal, fT3, fT4<\/li>\n\t\t<li>tumor markers&nbsp;<\/li>\n\t\t<li>inflammation indicators (CRP, ESR)<\/li>\n\t\t<li>indicators of blood coagulation<\/li>\n\t<\/ul>\n\t<\/li>\n\t<li>abdominal ultrasound scan<\/li>\n\t<li>CT scan\/MRI or PET-CT of abdomen<\/li>\n\t<li>preoperative care<\/li>\n\t<li>cytoreductive surgery to remove visible tumors<br \/>\n\tinside the abdomen and HIPEC<\/li>\n\t<li>histological and immunohistochemical<br \/>\n\texamination of removed tissues<\/li>\n\t<li>symptomatic treatment<\/li>\n\t<li>cost of essential medicines<\/li>\n\t<li>nursing services<\/li>\n\t<li>stay in the hospital with a full board<\/li>\n\t<li>accommodation in a 2-bedroom ward<\/li>\n\t<li>elaboration of further recommendations<\/li>\n<\/ul>\n<div class=\"program_how_program_going mt-4\"><h4>How program is carried out<\/h4><p style=\"text-align:justify\"><strong>During the first visit<\/strong>, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong>&nbsp;begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.<\/p>\n\n<p style=\"text-align:justify\">At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can&rsquo;t be detected by the naked eye).<\/p>\n\n<p style=\"text-align:justify\">After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. 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Multimodality treatment of ovarian cancer with cytoreductive surgery and HIPEC in University Hospital Oldenburg

University Hospital Oldenburg

Oldenburg, Germany
Program id # 639470
Doctor photo
Prof. Dr. med. Eduard Malik
Department of Gynecology, Mammology and Obstetrics
Specialized in: gynecology, mammology, obstetrics

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process ovaries, areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)

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About the department

The Department of Gynecology, Mammology and Obstetrics at the University Hospital Oldenburg provides a full range of high-precision diagnostics and effective treatment of diseases of the female reproductive system and breast pathologies. The department offers high-quality obstetric services: comprehensive pregnancy management, childbirth, and postpartum care for mother and child. The department's team of gynecologists specializes in the conservative and surgical treatment of pathologies of the female reproductive system. The department specializes in minimally invasive surgery for oncological gynecological diseases and interventions for breast cancer (certified by the German Cancer Society, DKG). The medical facility has 3 high-tech operating theaters where more than 3,000 surgical procedures are performed annually, many of them on an outpatient basis. The department has 48 beds for patient hospitalization. The department has the status of a Level I Perinatal Center, so expectant mothers are guaranteed exceptional quality of obstetric services. More than 2,000 babies are born in the department each year. The department is headed by Prof. Dr. med. Eduard Malik.

The priority area of ​​work of the department's gynecologists is the treatment of malignant diseases of the female reproductive system: cervical cancer, uterine cancer, ovarian cancer, and vulvar cancer. The first-line treatment for the above-mentioned oncological diseases is usually tumor resection surgery, while advanced stages may require more extensive surgery with removal of the uterus, ovaries, fallopian tubes, and affected pelvic lymph nodes. When clinically indicated, surgery is performed using a minimally invasive approach, which is less invasive and promotes rapid recovery in the postoperative period. Surgery is complemented by conservative treatments such as chemotherapy, radiation therapy, hormone therapy, and immunotherapy. The diagnosis of cancer always affects the emotional state, therefore the department offers the services of a competent psychologist: a specialist helps to cope with apathy and depressive states and to set up for a positive outcome of the therapy.

Another important ​​clinical focus of the department is the treatment of cervical dysplasia. Since 2016, a specialized center for the treatment of this gynecological pathology, certified in accordance with the standards of the German Cancer Society (DKG), has been operating on the basis of the department. The main danger of cervical dysplasia is that it may potentially lead to the development of an oncological process. In this regard, the specialists try to identify the pathology and carry out the treatment as soon as possible. When prescribing treatment, the gynecologist takes into account the stage of cervical dysplasia: early stages of the disease can be treated with pharmacotherapy; in more complex cases, the department's doctors prefer such less traumatic methods as cryodestruction, electrocoagulation, radiofrequency, and laser therapy. The last-line treatment is surgery, during which gynecologists remove the affected area of ​​the cervix or perform its amputation – this is a sparing operation that allows to get rid of cervical dysplasia and preserve fertility.

For more than 20 years, the department has been successfully treating breast diseases, the most common and dangerous of which is cancer. In 2004, the department was certified in accordance with the requirements of the German Cancer Society (DKG), and has been successfully recertified on a regular basis. Patients with breast cancer are treated in close cooperation with oncologists, radiotherapists, nuclear medicine specialists, and radiologists, which helps to achieve the best results. The therapeutic process begins with a comprehensive diagnosis that includes ultrasound and mammography; if suspicious changes are detected, magnetic resonance imaging and biopsy are performed. It should be noted that the department uses vacuum-assisted breast biopsy with the innovative Mammotome device. This type of biopsy is performed under local anesthesia on an outpatient basis, while it is minimally traumatic and can detect the slightest pathological changes in the mammary gland. Once the diagnosis is confirmed, breast specialists begin to develop an individualized treatment regimen. The first-line treatment is usually surgery. It is noteworthy that most breast cancer surgeries are organ-preserving, which makes it possible to avoid complete removal of the mammary gland. In complex cases, doctors perform a mastectomy. After such surgery, patients are offered breast plastic surgery using silicone implants, lipofilling, or a combination of the two. Surgery is usually accompanied by conservative treatment: specialists perform chemotherapy, hormone therapy, immunotherapy, and radiotherapy.

The department's team of obstetricians provides comprehensive medical care before, during, and after childbirth. The department has three state-of-the-art labor and delivery suites with specialized birthing chairs and monitoring systems. In addition to traditional obstetrical services, aromatherapy baths, homeopathy, and acupuncture are available to help relieve pain during labor. The labor and delivery suite also includes a water birth room, ultrasound rooms, a neonatal intensive care unit, and a specially equipped operating room for cesarean sections. The department's obstetricians are highly professional in their field and have a wealth of experience with high-risk and multiple pregnancies. Each year, more than 2,000 babies are born in the department's delivery rooms, so it is no surprise that the department enjoys the status of one of the best and largest maternity hospitals in Germany.

The department's range of medical services includes the following:

  • Gynecology
    • Minimally invasive surgery through a vaginal approach
      • Hysterectomy (surgical removal of the uterus)
      • Surgery for benign vaginal and labial neoplasms
      • Surgery for the creation of an artificial vagina
      • Vaginoplasty
      • Sling procedures for urinary incontinence
    • Laparoscopic surgery on the pelvic organs
      • Surgery for fallopian tube and ovarian diseases (for example, removal of cysts and sterilization)
      • Surgery for uterine diseases (for example, removal of fibroids and malignant tumors)
      • Surgery for endometriosis
      • Adhesiolysis
    • Robotic surgery using the da Vinci system for benign and malignant gynecological diseases
  • Mammology
    • Surgery for breast cancer
      • Breast-conserving surgery for breast cancer
      • Reconstructive breast plastic surgery after radical mastectomy using silicone implants, lipofilling techniques, or a combination of both
    • Surgery for benign breast diseases
    • Reconstructive breast plastic surgery for congenital and acquired malformations: breast augmentation and reduction
  • Obstetrics
    • Prenatal ultrasound diagnostics
    • Intrauterine therapy for congenital fetal abnormalities
    • Childbirth and postnatal care for mother and child and pain relief during childbirth using epidural anesthesia, acupuncture, homeopathy, aromatherapy, etc.
  • Other medical services in gynecology, mammology, and obstetrics

Curriculum vitae

Since April 1, 2006, Prof. Dr. med. Eduard Malik has been the Head Physician of the Department of Gynecology, Mammology and Obstetrics at the University Hospital Oldenburg. Prior to that, he worked in the Department of Gynecology at the University Hospital Regensburg. He graduated from the University of Hamburg and received his medical degree from the Johann Wolfgang Goethe University Frankfurt. In 2000, he completed his habilitation at the University Hospital Luebeck. From 2002 to 2004, Dr. Eduard Malik was a Senior Physician and Deputy Medical Director at the University Hospital Aachen. In 2004, he was appointed as a Professor at the University of Regensburg.

Prof. Malik's clinical interests include the treatment of malignant diseases of the female reproductive system and the performance of minimally invasive gynecologic procedures. His scientific work focuses on the study of endometriosis.

Photo of the doctor: (c) Klinikum Oldenburg AöR


About hospital

The University Hospital Oldenburg is a multidisciplinary medical complex offering top-notch services of the European standard. The hospital has 20 specialized departments, 15 highly specialized centers, and more than 10 institutes. The hospital provides services in almost all areas of modern medicine: general and abdominal surgery, cardiac surgery, orthopedics, traumatology, cardiology, oncology, dermatology, gastroenterology, gynecology, mammology, urology, and pediatric and adolescent medicine.

The hospital has 832 beds, and many diagnostic and therapeutic procedures are performed on an outpatient basis. More than 150,000 patients are treated here annually, 37,000 of them receive medical care in a hospital setting. The medical complex has a highly professional medical team of more than 2,900 employees and most departments are headed by professors with extensive clinical experience.

The hospital is home to one of the best comprehensive cancer centers in Germany (Nordwestdeutsches Tumorzentrum), certified according to the requirements of the German Cancer Society (DKG). The center successfully treats breast cancer, prostate cancer, colorectal cancer, pancreatic cancer, esophageal cancer, head and neck tumors, skin tumors, and other oncological diseases. The center uses modern cancer treatment methods with proven effectiveness and also offers allogeneic and autologous bone marrow transplantation for the treatment of severe hematologic diseases (European certification JACIE).

The University Hospital Oldenburg is an expert medical facility in robotic surgery. The hospital has a specialized da Vinci Surgery Center, where gastrointestinal, urological, and gynecological diseases are treated with excellence. Patients are operated on by highly qualified professors with in-depth expertise and extensive experience in robotic surgery.

The University Hospital Oldenburg is one of the leading medical institutions in Germany because it offers excellent medical and technical resources, qualified personnel, and a comfortable infrastructure designed with the needs of patients in mind. The hospital's physicians treat patients with complex clinical cases and achieve incredible results.

The basis of medical care in the hospital is humane attitude to the patient, empathy and understanding of his needs. During the therapeutic process, the patient is surrounded by care and, if necessary, receives professional psychological support.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients at the University Hospital Oldenburg stay in comfortable single, double, and triple rooms. Each patient room has an ensuite bathroom with a toilet and a shower. The patient rooms have a TV, a telephone, and Wi-Fi. The patient rooms in the pediatric departments are designed in an appropriate interior to make the young patients feel as comfortable as possible. A child can stay in the same room with one of the parents.

The hospital has an excellent infrastructure: there is a pharmacy, a hairdresser, an ATM, and a library with audio books, DVD movies, and board games.

Meals and Menus

The hospital offers delicious and balanced meals three times a day: breakfast, lunch, and dinner. Since 2022, a new menu "Vitalessen" has been introduced here, which excludes the addition of preservatives, dyes, and flavor enhancers to food. The menu takes into account all preferences and wishes of the patients.

There is also a cozy cafe in the hospital, where you can enjoy a tasty snack or a cup of aromatic coffee or hot tea with dessert.

Further details

Standard rooms include:

Toilet

Shower

Wi-Fi

TV

Religion

There is a chapel on the ground floor of the hospital where Catholic and Evangelical services are held regularly. Services by representatives of other religions are available upon request.

Accompanying person

Your accompanying person may stay with you in your patient room or at the hotel of your choice during the inpatient program.

Hotel

You may stay at the hotel of your choice during the outpatient program. Our managers will support you for selecting the best option.