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Chemotherapy and radiation therapy of multiple myeloma (program ID: 126047)

University Hospital Rechts der Isar Munich

location_on Munich, Germany
9.8/10 from 70 Votes
Specialized hospital
Florian Bassermann

Head Physician
Prof. Dr. med.

Florian Bassermann

Specialized in: hematology, oncology

Department of Hematology and Oncology

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • urinalysis for Bence Jones protein
    • differential blood count
    • protein electrophoresis
    • immunofixation
    • TSH-basal, fT3, fT4
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • CT-planning of radiation therapy
  • full course of conventional radiation therapy
  • individual plan of chemotherapy, the cost of medicines is included
  • symptomatic treatment
  • cost of essential medicines and materials
  • nursing services
  • control examinations
  • consultations of related specialists

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of previous laboratory tests and instrumental examinations. After that, you will undergo an additional examination, including complete blood count, laboratory assessment of liver and kidney function. Based on the received results, the physician will elaborate the chemotherapy regimen, conduct radiotherapy planning with the help of CT or MRI, make the permanent tattoo marks on the skin and conduct CT simulation in order to assess the accuracy of the rays and the radiation dose. If necessary, related medical specialists will be involved in the elaboration of a treatment regimen (tumor board).

Chemotherapy and radiation therapy are carried out as the day hospital procedure, without mandatory admission to the hospital. At each visit, the physician will assess your general condition and the marks on the skin. After that, you will be placed in a shielded radiation therapy room, on a special table.

Each radiation therapy session lasts less than half an hour (including preparation). All this time, doctors and nurses are monitoring your condition, you can communicate with them through a loudspeaker. The procedure is completely painless. Depending on the planned course of treatment, you will visit the hospital from 1 to 3-5 times a week.

During the chemotherapy session, after the placement of a venous catheter, you will stay in a comfortable ward. An infusion system will be connected to the catheter, through which the required drug or a drug combination will be administered. All drugs are administered by intravenous drip, slowly, so the total duration of the infusion can be up to several hours. All this time, doctors and nurses will monitor your health condition closely.

After the completion of the chemotherapy and radiation therapy course, you will undergo control examinations aimed at assessing your condition and efficacy of treatment. After that you will receive the medical report with detailed recommendations regarding further follow-up and treatment. In the future, you will be able to have a distant consultation with your attending physician and schedule the next course of treatment, if necessary.

Required documents:

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Bone marrow biopsy results (if available)
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About the department

The Department of Hematology and Oncology at the University Hospital Rechts der Isar Munich offers the full range of diagnostic and therapeutic services in these fields. The highly qualified team of the department's doctors provides effective treatment of all cancers and blood pathologies (for example, leukemia, multiple myeloma, non-Hodgkin's and Hodgkin's lymphoma) in accordance with the very latest international standards. The department performs autologous and allogeneic bone marrow transplantation, as well as provides innovative CAR T-cell therapy. It should be noted that the department is certified as the Comprehensive Cancer Center Munich, and also has a quality certificate from the German Cancer Society. The medical facility has the very latest equipment, implements innovative treatment methods, and at the same time pays due attention to comprehensive consultations and a humane attitude towards patients. Patients can get special nutrition counselling, as well as competent psychological care. The department is headed by Prof. Dr. med. Florian Bassermann.

Treatment tactics are developed at interdisciplinary tumor boards with the participation of hematologists, oncologists, surgeons, radiation therapists, radiologists, specialists in the field of pathological anatomy and nuclear medicine, so that each patient receives an optimal treatment plan corresponding to his particular clinical case. The department's main therapeutic options include classical chemotherapy, high-dose chemotherapy, targeted therapy, multimodal therapy, immunotherapy, radiation therapy, combined chemoradiation therapy, surgical treatment methods, etc.

It is worth highlighting the progressive type of CAR T-cell therapy. The essence of this treatment method is the collection of T-cells from the patient's body using apheresis and their follow-up processing, which makes it possible to program leukocytes for recognizing and destroying cancer cells. Once processed, leukocytes will be administered into the patient's body by an intravenous infusion. CAR T-cell therapy has shown excellent results, especially in cases where other treatment methods have failed. Another advantage of this therapeutic option is the low risk of side effects after the course of treatment. Even if they do develop, the side effects are temporary and can be easily controlled with medications. Indications for CAR T-cell therapy are aggressive lymphomas, acute lymphoblastic leukemia, and advanced multiple myeloma.

The department is also justly proud of its achievements in the field of autologous and allogeneic bone marrow transplantation. The doctors of the medical facility have over 30 years of successful experience in the field of autologous bone marrow transplantation. This procedure is indicated to patients with multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas, germ cell tumors, sarcomas, etc. Allogeneic transplantation has been performed in the department since 2002. This type of treatment can be used in patients with acute or chronic leukemia, multiple myeloma, myelodysplastic syndromes, myeloproliferative neoplasms, and severe aplastic anemia. The department has a certificate from the Joint Accreditation Committee JACIE, which confirms the high competence of the medical facility in this area.

The department provides diagnostics and treatment of the following diseases:

  • Hematology
    • Acute and chronic leukemia
    • Malignant lymphomas (Hodgkin's and non-Hodgkin's lymphomas)
    • Multiple myeloma (plasmacytoma)
    • Chronic myeloproliferative diseases
    • Myelodysplastic syndrome (MDS)
  • Oncology
    • Small cell and non-small cell lung cancer
    • Malignant gastrointestinal tumors (esophageal, stomach, pancreatic, colon cancers)
    • Gastrointestinal stromal tumors
    • Malignant endocrine tumors (thyroid, parathyroid, adrenal cancers)
    • Malignant bone and soft tissue tumors (sarcomas)
    • Malignant tumors of the female reproductive system (uterine and cervical cancers, ovarian, vulvar, vaginal, fallopian tube cancers)
    • Malignant tumors of the male reproductive system (prostate, testicular cancers)
    • Malignant head and neck tumors 
    • Skin cancer
    • Kidney and bladder cancers
  • Other hematological and oncological diseases

The department's diagnostic and therapeutic range of services includes:

  • Surgical treatment
  • Chemotherapy
  • Targeted therapy
  • Multimodal therapy
  • Immunotherapy
  • Radiation therapy
  • Combined chemoradiotherapy
  • CAR T-cell therapy
  • Autologous and allogeneic bone marrow transplantation
  • Other treatment methods

Curriculum vitae

Prof. Bassermann studied Medicine in Ulm, Munich and New York. He received his doctoral degree from the Technical University of Munich. The doctor began his clinical and scientific career at the Technical University of Munich, even before becoming a Postdoctoral Fellow at New York University (2006 - 2009). After returning to the Technical University of Munich, he became the Head of the Emmy Noether Junior Research Group (funding from the German Research Foundation). Here he had his board certification in Internal Medicine, Hematology and Oncology, as well as habilitation. In 2011, he was appointed as Senior Physician, and in 2015, he was invited to the position of Professor at the Technical University of Munich. Since November 2017, Prof. Bassermann has been the Head of the Department of Hematology and Oncology at the University Hospital Rechts der Isar Munich.

Awards and Honors

  • 2015 ERC Consolidator Grant.
  • 2015 Langener Science Prize.
  • 2015 Theodor Frerichs Prize, German Society of Internal Medicine (DGIM).
  • 2010 Walther Flemming Medal, German Society of Cell Biology (DGZ).
  • 2009 Participation in the Emmy Noether Program of the German Research Foundation.

Photo of the doctor: (c) Klinikum rechts der Isar der Technischen Universität München


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