Chemotherapy and radiotherapy for glioblastoma (program ID: 280822)

University Hospital Rechts der Isar Munich

location_on Munich, Germany
9.8/10 from 70 Votes
Specialized hospital
Stephanie Combs

Head Physician
Prof. Dr. med.

Stephanie Combs

Specialized in: radiation oncology, radiation therapy

Department of Adult and Pediatric Radiation Oncology, Radiation Therapy

Program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • physical examination
  • neurological examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers
    • indicators of blood coagulation
  • CT/MRI of head
  • full course of chemotherapy
  • full course of radiation therapy
  • control MRI
  • cost of essential medicines and materials
  • nursing services
  • consultations of leading experts
  • explanation of individual treatment plan

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of previous laboratory tests and instrumental examinations. After that, you will undergo an additional examination, including complete blood count, laboratory assessment of liver and kidney function. Based on the received results, the physician will elaborate the chemotherapy regimen, conduct radiotherapy planning with the help of CT or MRI, make the permanent tattoo marks on the skin and conduct CT simulation in order to assess the accuracy of the rays and the radiation dose. If necessary, related medical specialists will be involved in the elaboration of a treatment regimen (tumor board).

Chemotherapy and radiation therapy are carried out as the day hospital procedure, without mandatory admission to the hospital. At each visit, the physician will assess your general condition and the marks on the skin. After that, you will be placed in a shielded radiation therapy room, on a special table.

Each radiation therapy session lasts less than half an hour (including preparation). All this time, doctors and nurses are monitoring your condition, you can communicate with them through a loudspeaker. The procedure is completely painless. Depending on the planned course of treatment, you will visit the hospital from 1 to 3-5 times a week.

During the chemotherapy session, after the placement of a venous catheter, you will stay in a comfortable ward. An infusion system will be connected to the catheter, through which the required drug or a drug combination will be administered. All drugs are administered by intravenous drip, slowly, so the total duration of the infusion can be up to several hours. All this time, doctors and nurses will monitor your health condition closely.

After the completion of the chemotherapy and radiation therapy course, you will undergo control examinations aimed at assessing your condition and efficacy of treatment. After that you will receive the medical report with detailed recommendations regarding further follow-up and treatment. In the future, you will be able to have a distant consultation with your attending physician and schedule the next course of treatment, if necessary.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Biopsy results (if available)
Type of program :
Expected duration of the program:

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About the department

According to the Focus magazine 2017, the Department of Adult and Pediatric Radiation Oncology, Radiation Therapy at the University Hospital Rechts der Isar Munich ranked among the top German departments specializing in radiation therapy!

The department offers the full range of services in these medical focuses. The doctors of the department provide patients with comprehensive, individual consultations and radiation therapy using the latest medical technologies, which ensure high accuracy of irradiation and sparing treatment. There are many innovative forms of radiation therapy available that can effectively combat all types of cancer. The department is headed by Prof. Dr. med. Stephanie Combs.

The medical team of the department consists of highly qualified specialists in the field of neuro-oncology (treatment of brain tumors), pediatric radiation therapy (treatment of oncological diseases in children), gynecologic oncology (treatment of breast cancer and female genital tumors), uro-onocology (treatment of prostate cancer, cancer bladder), excellent doctors in the field of treatment of head and neck tumors, thoracic and gastrointestinal tumors. In addition, the department specializes in the treatment of benign diseases, for example, tennis, golfer’s elbow, arthrosis, other inflammatory and degenerative joint diseases.

The department offers the following therapeutic options:

  • Stereotactic radiation therapy is conducted within the "Center for Stereotaxy and Personalized High-Precision Radiation Therapy" (STEREOTAKTUM). The special advantages of this method include high accuracy, the achievement of effective results in just a few sessions of treatment and good compatibility with other therapies. This type of therapy is best suited for the treatment of small lung, liver, brain tumors.
  • Intensity-modulated radiation therapy allows carrying out the most accurate (up to a millimeter) targeted irradiation, which helps to protect healthy tissues from any damage. This therapy is the most common in the department’s clinical practice. With appropriate indications, this type of therapy is supplemented with tomotherapy.
  • Image-guided radiation therapy is carried out with the latest accelerators and computed tomography.
  • Gating irradiation of the thorax ("respiratory gating") is used for postoperative treatment of patients with left-sided breast cancer. This method allows to significantly reduce the burden on the heart.
  • 3D-conformal radiation therapy is a method of irradiation, the technology of which is based on volumetric planning for the most accurate irradiation. This is mostly conducted with the use of CT, MRI or PET (only in some tumors).
  • Tomotherapy is one of the very latest technologies of radiation therapy. It combines computerized tomography (CT) and linear accelerator in one system. During irradiation, the radiation source rotates around the patient.
  • Brachytherapy is a method, in which the radiation source is injected directly into the tumor. Radiation sources are radioactive substances that emit only a short distance. This is one of the most effective prostate cancer treatments.
  • Total body irradiation serves to destroy the remaining malignant cells in the bone marrow after chemotherapy. After total body chemotherapy and radiation therapy, bone marrow or stem cells are transplanted to replace blood stem cells. The procedure is performed with a linear accelerator.
  • Radiation therapy for the treatment of oncological diseases in children
  • Other types of radiation therapy

Curriculum vitae

  • 10/1996 - 04/2003 Medical Faculty of the Ruprecht Karls University Heidelberg, Eastern Virginia Medical School, Norfolk, VA, USA, University of Texas (UTHSCSA), San Antonio, TX, USA.
  • 04/2003 State Examination.
  • 04/2003 Doctor of Medicine, Ruprecht Karls University Heidelberg, Institute of Neuroanatomy (Prof. Dr. K. Unsicker). Subject: "TGF-βs, PACAP and the Development of the Sympathoadrenal Cell Lineage" (magna cum Laude).

Professional Experience

  • 06/2003 - 03/2014 Postdoctoral position and Residency, Department of Radiation Oncology, University Hospital Heidelberg, Germany.
  • Radiation Oncology, Deutsches Krebsforschungszentrum (DKFZ), Director: PD Dr. Dr. J. Debus.
  • 2007 - 2014 Head of the Neuroradiation Oncology Research Group, Department of Radiation Oncology, University Hospital Heidelberg, Germany.
  • 02/2009 Board Certification, Radiation Protection.
  • 07/2009 Board Certification, Radiation Oncology.
  • 10/2009 Consultant, Department of Radiation Oncology, University Hospital Heidelberg, Germany.
  • 12/2009 Postdoctoral Lecturer, Habilitation in Radiation Oncology.
  • 2011 - 2014 Deputy Head, Department of Radiation Oncology, University Hospital Heidelberg, Germany.
  • 11/2011 Diploma in Palliative Care.
  • Since 04/2014, Professor and Head of the Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Germany.
  • Since 04/2014, Director, Institute of Innovative Radiotherapy (iRT), Helmholtz Center Munich, Germany.

Photo of the doctor: (c) Klinikum rechts der Isar der Technischen Universität München

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