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Multimodality treatment of mesothelioma with cytoreductive surgery and HIPEC (639617) | University Hospital Würzburg - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.<\/p>\n\n<p style=\"text-align:justify\"><strong>Cytoreductive surgery<\/strong> begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process areas of the peritoneum and metastases in other internal organs. 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Multimodality treatment of mesothelioma with cytoreductive surgery and HIPEC in University Hospital Würzburg

University Hospital Würzburg

Würzburg, Germany
Program id # 639617
Doctor photo
Prof. Dr. med. Rainer G. Leyh
Department of Adult and Pediatric Cardiothoracic Surgery
Specialized in: adult and pediatric cardiothoracic surgery

The program includes:

  • Initial presentation in the clinic
  • clinical history taking
  • review of medical records
  • physical examination
  • laboratory tests:
    • complete blood count
    • general urine analysis
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • tumor markers 
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT scan/MRI or PET-CT of abdomen
  • preoperative care
  • cytoreductive surgery to remove visible tumors
    inside the abdomen and HIPEC
  • histological and immunohistochemical
    examination of removed tissues
  • symptomatic treatment
  • cost of essential medicines
  • nursing services
  • stay in the hospital with a full board
  • accommodation in a 2-bedroom ward
  • elaboration of further recommendations

How program is carried out

During the first visit, the physician will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan and tomography of the abdominal organs. Based on the results of the examination, the physician will choose the surgical technique and the type of anesthesia. After that, preparation according to the preoperative standard will start.

Cytoreductive surgery begins with general anesthesia. The intervention is performed as open surgery, i.e. through the incision in the anterior abdominal wall, so that the surgeon can carefully examine the peritoneum and the surface of the abdominal organs. The surgeon removes affected by the malignant process areas of the peritoneum and metastases in other internal organs. This stage of the operation can take several hours, since the overall effectiveness of the treatment depends on the completeness of the malignant tissues removal.

At the next stage of the operation, the surgeon inserts several catheters into the abdominal cavity. Through the catheters, a heated solution of a chemotherapy drug is pumped inside. The special system maintains the required temperature (42-43 degrees Celsius), pressure and circulation rate of the medicinal solution. The solution mechanically flushes out blood clots and remnants of malignant tissues, and a heated chemotherapy drug destroys micrometastases in internal organs and lymph nodes (micrometastases can’t be detected by the naked eye).

After 1-1.5 hours, the chemotherapy drug is removed from the abdominal cavity and the abdominal cavity is washed with saline. After that, the surgeon removes the catheters and sutures the incision of the anterior abdominal wall.

After the completion of the operation, you will be transferred to the ward of the intensive care unit, under the round-the-clock supervision of doctors and nurses. In 1-3 days after the operation, your drains will be removed and you will be transferred to a regular ward for further recovery. The whole treatment takes 10-12 days on average.

Finally, the attending physician will evaluate the results of control examinations, schedule the date of discharge from the hospital and give you detailed recommendations for further follow-up and treatment.

Required documents

  • Medical records
  • X-ray examination, MRI/CT scan (if available)
  • Pleural biopsy (if available)

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About the department

According to the Focus magazine, the Department of Adult and Pediatric Cardiothoracic Surgery at the University Hospital Würzburg is included in the ranking of the top departments in Germany specializing in the surgical treatment of diseases of the cardiovascular system! 

The department offers the surgical treatment of all congenital and acquired heart diseases in adulthood, including heart transplantation, as well as the treatment of respiratory diseases in adults and children. It performs more than 2,000 interventions on the heart and about 600 operations on the lungs every year. Of particular interest is minimally invasive surgery, coronary artery bypass grafting, as well as heart valve reconstruction and implantation, interventions on the lungs, thorax and mediastinum, diaphragm. The Chief Physician of the department is Prof. Dr. med. 
Rainer G. Leyh.

Special attention should be paid to the technical equipment and infrastructure of the department. The Intensive Care Unit, the Intermediate Care Unit, as well as the state-of-art operating rooms for performing interventions of any severity, including robotic surgery and sparing minimally invasive procedures are available for the treatment of patients.

In daily professional activities, all the department's specialists adhere to the basic credo, which involves the provision of the most sparing, individualized treatment in accordance with the highest medical standards.

The service range of the department includes:

  • Cardiac surgery
    • Diagnostics and surgical treatment of heart valve diseases
      • Surgical correction of heart valves
      • Heart valve replacement (biological and artificial implants)
      • Heart valve replacement using the catheter techniques
      • Minimally invasive interventions on heart valves
      • Ross procedure in aortic valve replacement
      • Transcatheter aortic valve implantation (TAVI)
    • Diagnostics and treatment of coronary stenosis
      • Drug therapy
      • Stent implantation
      • Coronary artery bypass grafting (classic and innovative minimally invasive techniques)
    • Diagnostics and surgical treatment of aneurysms, aortic dissection
      • Open aortic replacement
      • Endovascular stent implantation
      • Hybrid interventions
    • Diagnostics and surgical treatment of heart rhythm disorders
      • Implantation of pacemakers
      • Implantation of defibrillators
    • Diagnostics and treatment of atrial fibrillation
      • Drug therapy
      • Catheter ablation
      • Surgical intervention
    • Diagnostics and surgical treatment of heart failure
      • Artificial heart implantation
      • Removal of ventricular aneurysm
    • Heart transplantation
    • Robotic surgery
  • Thoracic surgery
    • Thoracic surgical oncology
      • Removal of thoracic and mediastinal tumors
      • Removal of lung tumors
      • Removal of metastases in the thoracic organs
      • Treatment of pleural mesothelioma
    • Septic thoracic surgery
    • Surgical interventions on the pleura (in pleural effusion, pneumothorax)
    • Pediatric thoracic surgery
      • Cystic adenomatoid lung malformation
      • Congenital lobar emphysema
      • Pulmonary sequestration
    • Correction of congenital thoracic defects
      • Pectus excavatum
      • Pectus carinatum
    • Diagnostics and surgical treatment of chronic obstructive pulmonary disease
  • Diagnostics and surgical treatment of other diseases of the cardiovascular system, respiratory system

Curriculum vitae

Education and Professional Training

  • 1981 - 1988 Study of Medicine, University of Kiel (Germany) and Auckland/Dunedin Universities, New Zealand.
  • 1988 - 1989 Army service (medical service).
  • 1990 Doctoral thesis defense, Christian Albrecht University of Kiel.
  • 1989 - 1993 Clinical training in the Department of Cardiac Surgery, Christian Albrecht University of Kiel.
  • 1993 - 1998 Continued clinical training in the Department of Cardiac Surgery at the University Hospital Lübeck.
  • 2003 Habilitation, Department of Cardiothoracic Surgery, Hannover Medical School.

Professional Experience

  • 1996 - 1999 Senior Physician of the Department of Cardiac Surgery at the University Hospital Lübeck.
  • 1999 - 2004 Senior Physician of the Department of Cardiothoracic Surgery, Hannover Medical School, Head of the Department of Cardiothoracic Surgery, Hannover Medical School, Ortstadtkrankenhaus Hannover.
  • 2004 - 2007 Deputy Head of the Department of Cardiothoracic Surgery, West German Heart Center, University Hospital Essen.
  • Since 2007, Head of the Department of Adult and Pediatric Cardiothoracic Surgery at the University Hospital Würzburg.

Main Clinical Focuses

  • Surgical treatment of heart failure.
  • Heart valve reconstructive surgery.
  • Aortic surgery.

Photo of the doctor: (c) Universitätsklinikum Würzburg 


About hospital

According to the FOCUS magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals!

The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and advanced expert experience. The hospital is the maximum care medical center and covers all fields of modern medicine. The hospital has an impeccable international reputation and treats a large number of patients from other countries every year.

A distinctive peculiarity of the hospital is active interdisciplinary cooperation. A large number of diseases are diagnosed and treated within the specialized centers, which medical teams rely on the unique experience of treatment of a wide variety of clinical cases. For example, such centers include the General Cancer Center, the Stem Cell Therapy Center, the Breast Health Center, the Gastrointestinal Center, the Thoracic Surgery Center, etc. In total, the hospital has more than 40 centers of this kind. Therefore, the patients of the hospital are confident that they will be offered the most relevant treatment in accordance with the very latest medical recommendations.

In addition to the most advanced achievements and methods of modern medicine, the medical team of the hospital makes every effort to create a comfortable, friendly atmosphere, which promotes patient well-being and recovery.

Photo: (с) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital Würzburg live in comfortable rooms made in a modern design and bright colors. The patient room includes a bed with a remote control, a bedside table with a sliding table, a wardrobe, a TV. The patient rooms have the possibility of Internet connection. The enhanced-comfort rooms are equipped with a safe, a fridge and upholstered furniture.

Meals and Menus

The patients of the hospital are offered a varied and tasty three meals a day. There is a daily choice of several menus, including a dietary one. In case of intolerance to any food, please inform the medical staff about your food preferences in advance. After that, you will be offered an individual menu. Also, the hospital houses the cafes and cafeterias with a wide assortment of drinks, fresh pastries, fresh salads, sweets and other dishes.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

Christian priests are available for the patients at any time. Representatives of other religions may be requested at any time.

Accompanying person

Your companion may stay with you in your room or at a hotel of your choice during the fixed program.

Hotel

You may stay at the clinic hotel or a hotel of your choice during the outpatient program. Our manager will help you choose the best option.