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Dermatofibrosarcoma Treatment in Germany - Best Hospitals, Doctors, Prices - Booking Health

Treatment of Dermatofibrosarcoma in Germany

Dermatofibrosarcoma Treatment in Germany | Information about hospitals and doctors | Rankings | Clinics | Prices | Send request to the hospital

Best children's hospitals and doctors for dermatofibrosarcoma treatment in Germany

Leading hospitals

Cost for treatment

Diagnostic for dermatofibrosarcoma
3465.8
Micrographic surgery for dermatofibrosarcoma
7055.18
Radiotherapy for dermatofibrosarcoma
19270.73
According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
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University Hospital Frankfurt am Main
Germany, Frankfurt am Main

University Hospital Frankfurt am Main

Overall rating10 / 10
According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
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Charite University Hospital Berlin
Germany, Berlin

Charite University Hospital Berlin

Overall rating9 / 10
According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
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University Hospital Würzburg
Germany, Würzburg

University Hospital Würzburg

Overall rating9.2 / 10
According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
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University Hospital Muenster
Germany, Muenster

University Hospital Muenster

Overall rating9.8 / 10
According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
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University Hospital Bonn
Germany, Bonn

University Hospital Bonn

Overall rating9.2 / 10
According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
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University Hospital Heidelberg
Germany, Heidelberg

University Hospital Heidelberg

Overall rating9.8 / 10
According to Focus magazine, the University Hospital Heidelberg ranks among the top five hospitals in Germany! The hospital is one of the most advanced and reputable medical institutions not only in Germany, but throughout Europe. There are more than 43 specialized departments and 13 medical institutes, which cover all fields of
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University Hospital Halle (Saale)
Germany, Halle

University Hospital Halle (Saale)

Overall rating9.6 / 10
According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
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University Hospital Essen
Germany, Essen

University Hospital Essen

Overall rating9.6 / 10
According to the authoritative Focus magazine the University Hospital Essen ranks among the top German hospitals! With 27 specialized departments and 24 institutes, the hospital in Germany is a maximum care medical facility. The hospital has 1,300 beds for inpatient treatment. A highly qualified medical team of more than 6,000 e
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University Hospital Rechts der Isar Munich
Germany, Munich

University Hospital Rechts der Isar Munich

Overall rating9.8 / 10
The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
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University Hospital Duesseldorf
Germany, Duesseldorf

University Hospital Duesseldorf

Overall rating9.5 / 10
According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
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University Hospital Tuebingen
Germany, Tuebingen

University Hospital Tuebingen

Overall rating9.2 / 10
According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
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University Hospital Carl Gustav Carus Dresden
Germany, Dresden

University Hospital Carl Gustav Carus Dresden

Overall rating9.1 / 10
According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
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University Hospital Saarland Homburg
Germany, Homburg

University Hospital Saarland Homburg

Overall rating9.8 / 10
The University Hospital Saarland Homburg is the largest hospital in the city of Homburg and the most important medical facility in the region. The hospital, which currently has 30 specialized departments and 20 institutes, was founded in 1947 and operates on the basis of Saarland University. The hospital plays a leading role in
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Asklepios Childrens Hospital Sankt Augustin
Germany, Sankt Augustin

Asklepios Childrens Hospital Sankt Augustin

Overall rating9.2 / 10
The Asklepios Children's Hospital Sankt Augustin positions itself as an ultramodern maximum care medical facility for children and adolescents. A distinctive feature of the hospital is the exceptionally high quality of medical service, a sensitive attitude and compassionate care for young patients. The hospital diagnoses and
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DKD HELIOS Clinic Wiesbaden
Germany, Wiesbaden

DKD HELIOS Clinic Wiesbaden

Overall rating9.2 / 10
The DKD HELIOS Clinic Wiesbaden has long made a name for itself in the international medical arena by introducing an optimal model of medical care, combining the use of the most advanced medical technologies, the experience of highly qualified doctors and impeccable quality of patient care. The medical facility first opened its
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| from Booking Health GmbH

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor affecting the skin and subcutaneous adipose tissue. Physically, the tumor is a slowly growing solid plaque. It most often develops on the torso in young people. A diagnosis is made by doing a skin biopsy. In Germany, the vast majority of cases are successfully treated. Clinics in Germany prefer the Mohs surgery, as it provides a 7-fold reduction in the risk of tumor recurrence compared to wide excision.

Content

  1. Mohs surgery
  2. Wide excision
  3. Drug therapy
  4. Radiation therapy

In Germany, the main treatment method is the Mohs microsurgery. The operation provides a low risk of recurrence and ensures excellent aesthetic results. After surgery, radiation therapy or drug therapy with tyrosine kinase inhibitors may be required.

You can undergo treatment in the following hospitals: University Hospital of Ludwig Maximilian University of Munich, University Hospital Frankfurt am Main, HELIOS Clinic Krefeld.

Please leave your request for the treatment of dermatofibrosarcoma on the Booking Health website, and our specialists will contact you immediately. They will help you select a clinic and a doctor, apply for a visa, get to the clinic, get medical insurance and communicate with doctors in the same language (interpreting services). Upon completing treatment and returning to your native country, you will be able to receive remote consultations from the attending physician until complete recovery.

Mohs surgery

 

Mohs micrographic surgery is considered the best treatment for dermatofibrosarcoma. This is a complex operation that is not performed in all medical centers. At the same time, it is the main one in German clinics.

The essence of the surgical technique is the multi-stage removal of the tumor, with a constant assessment of the state of the resection margin.

The doctor performs a tumor resection with minimal capture of the adjacent tissues. The material is then sent to the laboratory to assess the resection margin. After receiving the results, the doctor continues to cut the flaps, but only in the direction in which tumor cells are found. After each such stage, a repeated histological examination is carried out.

As a result, the operation can take several hours. It is continued until the resection margins are clear. Such an operation is more sparing and provides better aesthetic outcomes since the doctor does not have to remove tissue with a "reserve". This is especially important when the neoplasm is localized in areas where resection of a significant amount of tissue can lead to functional disorders.

Another advantage of the Mohs surgery is the low risk of tumor recurrence. It is associated with total histopathological control of the resection margin during surgery.

Wide excision

 

Wide excision is rarely used in developed countries, but this method is often used in countries with poorly developed medicine.

The essence of the surgical intervention is that the tumor is removed with an indentation of 2 to 4 cm from the visible margin of the neoplasm. The indentation depends on both the size of the tumor and its location, as well as on the requirements for the functional and aesthetic outcomes of the surgery.

After a wide local excision, the recurrence rate reaches 7,3%. At the same time, in the case of micrographic Mohs surgery, the probability of tumor recurrence is only 1%.

Dermatofibroma very rarely metastasizes to the lymph nodes, so in most cases, patients do not require additional surgical intervention on the lymphatic collector. As a result of refusing to remove lymph nodes, the treatment of the disease becomes less traumatic, the risk of complications is reduced, and the duration of oncological rehabilitation is reduced.

Drug therapy

 

The treatment of dermatofibrosarcoma in Germany involves using an oral tyrosine kinase inhibitor. Most patients do not require drug therapy. It is used for the following forms of dermatofibrosarcoma:

  • recurrent (returning after primary treatment)
  • unresectable (not subject to surgical removal)
  • metastatic

The best response to the treatment is achieved in patients with t(17;22) translocation. This genetic disorder is detected by the results of molecular biological diagnostics. Fluorescence in situ hybridization (FISH) or reverse transcription polymerase chain reaction (RT-PCR) is used in Germany.

The course of treatment lasts 6 months, and it is effective in two-thirds of patients.

Radiation therapy

 

In the case of dermatofibrosarcoma, radiation therapy is not very common. This is due to the fact that surgery is enough to cure this disease in most patients. The areas of application of radiation therapy are as follows:

  • after surgery – in case of high risk of recurrence
  • destruction of the recurrent tumor

After surgery, most recurrences occur within the first 3 years. Therefore, the most accurate monitoring of patients is carried out during these periods. They are examined every 3 months in the first year and every 6 months in the next 2 years. Then the frequency of examinations can be reduced to 1 time in 12 months. With a high risk of recurrence, the list of diagnostic tests includes a chest CT scan.

Patients who want to undergo diagnostics and treatment of dermatofibrosarcoma in Germany can book a medical care program via the international medical tourism agency Booking Health. When using this service, prices will be lower for you due to the lack of additional coefficients for foreign patients. The cost of treatment is guaranteed not to increase, as you will receive insurance coverage up to 200,000 euros. On our website, you can find out the price for surgical interventions and conservative procedures in different clinics in Germany and book your treatment on the most suitable dates. The Booking Health specialists will select a clinic for you and take care of the arrangement of your trip.

 

Authors: 

The article was edited by medical experts, board certified doctors Dr. Nadezhda Ivanisova and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

MedlinePlus

Sience Direct

PubMed