google_counter
background_img

Treatment of Oropharyngeal Cancer in Germany

Due to the difficulties associated with the organization of treatment in Turkey, Switzerland, South Korea and India, we are not currently processing requests to these regions.

If you are interested in treatment in Germany, please leave a request and our specialists will contact you as soon as possible.

 

Cost for treatment

Diagnostic tests for oropharyngeal cancer
787
Combined chemotherapy and radiotherapy for oropharyngeal cancer
20691
Surgery for oropharyngeal cancer
5518

University Hospital of Ludwig Maximilian University of Munich

10/10
location_onGermany, Munich

Department of Adult and Pediatric Otolaryngology

According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany! The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of i
Diagnostic tests for oropharyngeal cancer
1912
Combined chemotherapy and radiotherapy for oropharyngeal cancer
38259
Surgery for oropharyngeal cancer
18126

Helios Hospital Berlin-Buch

9.7/10
location_onGermany, Berlin

Department of Adult and Pediatric Otolaryngology

According to the reputable Focus magazine, the Helios Hospital Berlin-Buch ranks among the top medical facilities in Germany! The clinic is proud of its rich history, which dates back over 100 years, as well as the status of a maximum care medical center with exceptionally high success treatment rates. The medical institution is
Diagnostic tests for oropharyngeal cancer
1795
Combined chemotherapy and radiotherapy for oropharyngeal cancer
33831
Surgery for oropharyngeal cancer
15952

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of Adult and Pediatric Otolaryngology, Head and Neck Surgery

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnostic tests for oropharyngeal cancer
1969
Combined chemotherapy and radiotherapy for oropharyngeal cancer
35662
Surgery for oropharyngeal cancer
17163

University Hospital Frankfurt am Main

10/10
location_onGermany, Frankfurt am Main

Department of Adult and Pediatric Otolaryngology

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnostic tests for oropharyngeal cancer
2746
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29501
Surgery for oropharyngeal cancer
16218

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of Otolaryngology, Head and Neck Surgery

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnostic tests for oropharyngeal cancer
3566
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29831
Surgery for oropharyngeal cancer
20486

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of Adult and Pediatric Otolaryngology, Plastic and Aesthetic Surgery

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnostic tests for oropharyngeal cancer
2832
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29841
Surgery for oropharyngeal cancer
15800

University Hospital Jena

8.9/10
location_onGermany, Jena

Department of Adult and Pediatric Otolaryngology

According to the prestigious Focus magazine, the University Hospital Jena regularly ranks among the top German medical facilities! The hospital has positioned itself as a multidisciplinary medical facility with a long history of more than 200 years. Since its foundation, the hospital has been constantly developing and modernizin
Diagnostic tests for oropharyngeal cancer
3187
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29398
Surgery for oropharyngeal cancer
17927

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of Adult and Pediatric Otolaryngology, Head and Neck Surgery

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnostic tests for oropharyngeal cancer
1814
Combined chemotherapy and radiotherapy for oropharyngeal cancer
35819
Surgery for oropharyngeal cancer
17108

Charite University Hospital Berlin

9/10
location_onGermany, Berlin

Department of Adult and Pediatric Otolaryngology

According to the authoritative Focus magazine, the Charite University Hospital Berlin occupies the first place in the rating of the top German medical facilities! The hospital is one of the largest and leading university medical complexes in Europe. The hospital in Germany provides modern diagnostics and treatment of patients, a
Diagnostic tests for oropharyngeal cancer
3982
Combined chemotherapy and radiotherapy for oropharyngeal cancer
37858
Surgery for oropharyngeal cancer
23614

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of Adult and Pediatric Otolaryngology

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnostic tests for oropharyngeal cancer
2820
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29640
Surgery for oropharyngeal cancer
15873

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of Adult and Pediatric Otolaryngology, Head and Neck Surgery

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnostic tests for oropharyngeal cancer
2791
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29381
Surgery for oropharyngeal cancer
15970

University Hospital Bonn

9.2/10
location_onGermany, Bonn

Department of Adult and Pediatric Otolaryngology

According to the authoritative Focus magazine, the University Hospital Bonn ranks among the top ten medical facilities in Germany! The hospital was opened on January 1, 2001, although in fact it inherits the medical facility, which operated at the Faculty of Medicine of the University of Bonn. The hospital in Germany combin
Diagnostic tests for oropharyngeal cancer
3026
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29767
Surgery for oropharyngeal cancer
17737

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of Adult and Pediatric Otolaryngology

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Diagnostic tests for oropharyngeal cancer
1929
Combined chemotherapy and radiotherapy for oropharyngeal cancer
35625
Surgery for oropharyngeal cancer
16692

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of Adult and Pediatric Otolaryngology

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnostic tests for oropharyngeal cancer
3000
Combined chemotherapy and radiotherapy for oropharyngeal cancer
29527
Surgery for oropharyngeal cancer
18103

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Adult and Pediatric Otolaryngology

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnostic tests for oropharyngeal cancer
2660
Combined chemotherapy and radiotherapy for oropharyngeal cancer
36142
Surgery for oropharyngeal cancer
14906

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Adult and Pediatric Otolaryngology, Head and Neck Surgery, Facial Plastic Surgery

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Diagnostic tests for oropharyngeal cancer
3110
Combined chemotherapy and radiotherapy for oropharyngeal cancer
37837
Surgery for oropharyngeal cancer
17643
| from Booking Health GmbH

Oropharyngeal cancer is an aggressive tumor characterized by its rapid spread to the head and neck. It often metastasizes to regional lymph nodes and distant organs. You can undergo treatment for this disease in Germany. In this country, you will be treated with sparing laser interventions, new types of radiotherapy, and advanced medications. The Departments of Oncology in Germany provide top-class medical services.

Content

  1. What is oropharyngeal cancer?
  2. Principles of treatment
  3. Surgical treatment
  4. Radiotherapy
  5. Drug therapy
  6. Why is it worth undergoing cancer treatment in Germany?

What is oropharyngeal cancer?

 

The pharynx is an organ of the neck responsible for the swallowing function. It is located between the oral cavity and the esophagus. The pharynx is divided into three parts: nasal, oral and laryngeal. The oral part is called the oropharynx.

The development of a malignant tumor in this part of the organ is mostly caused by smoking, alcohol, or the human papillomavirus of high oncogenic risk. The HPV status (human papillomavirus infection) is taken into account in staging and influences the cancer treatment regimen.

Most oropharyngeal tumors develop in the tonsils (65% of cases).

The patients with oropharyngeal cancer at the early stages of the disease have the following symptoms:

  • swallowing awkwardness;
  • persistent sore throat, which is often misdiagnosed as chronic tonsillitis. 

When examining patients with cancer of the oropharynx, the doctor sees a tuberous formation, on the surface of which, in most cases, there are ulcers.

As the cancer progresses, it spreads to the retromolar region, the root of the tongue, the soft palate, and the palatine arches. At this stage, patients with oropharyngeal cancer suffer from severe pain that radiates to the ear and head. Patients with headaches usually cannot get rid of their symptoms with nonsteroidal, anti-inflammatory drugs.

With the decay of the oropharyngeal tumor, patients develop bad breath.

The disease has a high metastasis rate. In 75-80% of first-time patients, there are already metastases in regional lymph nodes. These often reach a larger size than the primary oropharyngeal tumor.

In 20% of patients, the neoplasm appears in the root of the tongue region. It disrupts the mobility of the organ, makes speech difficult, and makes patients uncomfortable when swallowing.

In 10% of patients, the primary tumor appears in the soft palate. Patients complain of pain, impaired speech, and swallowing.

In 5% of patients, the primary neoplasm is localized on the posterior wall of the oropharynx.

At the time of diagnosis, 15-30% of patients have distant metastases. The lungs and bones are the most commonly affected areas.

Principles of treatment

 

The preferred treatment method is surgery. Doctors in Germany perform operations for patients with oropharyngeal cancer using both a conventional, mechanical instrument and a laser.

The surgical interventions are as follows:

  • open – through skin incisions;
  • transoral – through the oral cavity.

Transoral interventions are considered the preferred ones. They are less traumatic, provide a better aesthetic result, and better functional outcomes. Nonetheless, these surgical interventions are also more complex and are best performed in a specialized medical center with more experience present. Therefore, many patients with oropharyngeal cancer prefer to receive the services of German doctors.

The operation is complemented by lymph node dissection: unilateral or bilateral.

Other primary treatment options: 

  • radiotherapy – as an independent version, it is safer for health; 
  • chemoradiotherapy – it is more toxic but also more effective. 

If surgery is chosen as the first method of treatment of oropharyngeal cancer, then the indications for postoperative radiotherapy and chemotherapy are determined individually. Adjuvant therapy in Germany is carried out when the tumor invades the capsule of the lymph node, as well as in the case of a positive resection margin. In the second case, a second surgery can also be performed.

If the first treatment for cancer was radiotherapy or chemoradiotherapy, then, after its completion, the patient is examined to check if there is a residual tumor. If it has regressed completely, additional treatment is not required. If there is a residual tumor, surgery is required for its removal.

In the advanced stages of oropharyngeal cancer, the treatment is usually conservative. The main options include:

  • chemoradiotherapy; 
  • induction chemotherapy followed by chemoradiotherapy. 

Some patients may undergo tumor removal surgery. If the risk of recurrence is high, postoperative radiation therapy or chemoradiotherapy is conducted.

Surgical treatment

 

In medical hospitals in Germany, surgical interventions are performed by surgeons who specialize in head and neck oncology. Therefore, you can be sure of good oncological results and minimal health risks.

Primary tumor removal is performed using an en-bloc technique. The doctor moves back from the margin of the visible neoplasm by at least 2 cm. After the operation, the material is examined. Good treatment results are predicted with a negative resection margin and a distance to cancer cells of at least 5 mm.

In specialized oncology hospitals in Germany, doctors often treat patients with a laser. The tumor is removed with access through the oral cavity, without skin incisions. If this is not possible, then a standard open operation is performed.

The tumor removal is followed by a reconstructive stage. Doctors can perform a resection of the adjacent organs that need to be restored: for example, a fragment of the lower jaw. It is restored with implants or autologous bone. In the future, the patient may need dental implants to restore their chewing function.

After the operation, some tissue defects will remain. In Germany, they are replaced with advanced or free flaps. In patients with defects on their skin, the doctor can perform a transplant to improve the person's appearance.

Lymph node dissection is a stage of surgery aimed at removing lymph nodes. It is required for most patients. Lymph node dissection is performed, even in the absence of clinical signs of damage to the lymphatic collector, in the following cases:

  • locally advanced cancer (T3, T4); 
  • primary tumor in the tonsils (these make up two-thirds of cases of oropharyngeal cancer); 
  • tonsillar fossa lesions;
  • cancer recurrence. 

In addition, lymph node dissection is indicated by the presence of at least one metastasis over 6 cm, multiple metastases over 3 cm, or the spread of the metastatic tumor beyond the lymph node capsule (to the jugular vein, common carotid artery, or sternocleidomastoid muscle).

Contraindications for surgery to treat oropharyngeal cancer are as follows:  

  • invasion of the neoplasm in the mediastinum; 
  • lesions of the prevertebral fascia and cervical vertebrae; 
  • the spread to the skin from the regional lymph nodes. 

In these cases, radical tumor removal is unlikely, and the risk of complications is high. Therefore, in Germany, such patients are usually treated with conservative methods.

Radiotherapy

 

Radiotherapy is one of the three main methods of treatment in oncology. In Germany, it is used both as an independent option and in combination with chemotherapy.

Proton therapy is considered the preferred treatment option for oropharyngeal cancer. However, this is an expensive, high-tech method that is only available in countries with advanced medicine. There are six Proton Therapy Centers in Germany, more than in any other country in Europe. Most foreign patients who receive medical services in Germany are treated at the University Hospital Heidelberg or the University Hospital Essen.

Proton therapy differs from standard photon therapy, in that it delivers radiation to the target more accurately. Protons particularly, do not damage the tissues through which they pass. They release most of their radiation only when they reach the tumor. As a result, there is less radiation exposure to the surrounding tissues, and a lower risk of post-radiation complications. This is especially important in head and neck cancer, because many important organs, large vessels, and nerves are located nearby, which increases the risk of side effects.

IMRT or VMAT are the preferred methods of photon radiation therapy if proton therapy cannot be performed for technical or financial reasons. These are new options for radiotherapy, and they are safer and very accurate. Doctors irradiate the primary tumor, or its bed, after surgical removal, as well as the site of the lymphatic collector.

Postoperative radiotherapy is optimally started within 6 weeks of surgery, immediately after the wound healing. The interval should not exceed 12 weeks.

Brachytherapy is a method of contact radiation therapy. It is used in specialized centers in Germany. It involves the implantation of radioactive seeds into the tumor. This therapy is only used at an early stage and can destroy small neoplasms.

Drug therapy

 

The main method of drug treatment is chemotherapy. Platinum-based medications are most effective for oropharyngeal cancer. In Germany, they are often used simultaneously with radiotherapy. Typically, doctors prescribe a three-drug regimen. In total, 2-3 courses, with an interval of 3 weeks, are required.

In oncology, drugs for targeted therapy and immunotherapy are increasingly being used: 

EGFR inhibitors slow or stop the growth of cancer cells. The effect is achieved by inhibiting the protein that stimulates the tumor growth. The drugs of this group are used not only in the advanced, but also in the early stages of cancer. They are combined with chemotherapy and radiation therapy. These drugs are safer for a patient’s health compared to chemotherapy. Therefore, they are sometimes used instead of platinum-based medications if the patient's health condition does not allow him to endure standard chemotherapy.

PD-1 inhibitors are drugs that enhance antitumor immunity. They are called immune checkpoint inhibitors. These drugs are prescribed as second-line therapy for patients whom chemotherapy and targeted therapy no longer work for. The drugs do not have a cytotoxic effect on cells, but only eliminate the protection of the tumor against the immune response. Therefore, they are relatively safe for health, although some people may have autoimmune reactions.

Why is it worth undergoing cancer treatment in Germany?

 

Germany offers highly developed medicine. Therefore, many neck cancer patients, patients with oropharyngeal cancer, and other head and neck tumors, prefer to treat their oncological diseases in this country. The country provides top-class medical services. Doctors successfully cope with the treatment of nasopharyngeal, oropharyngeal, laryngopharyngeal, oral cavity neoplasms, and other types of cancer.

Here are a few reasons for you to use the medical services of German doctors:

  • state-of-the-art equipment in hospitals due to good financing of medicine;
  • you will receive treatment from highly reputable doctors in the world of medicine;
  • sparing transoral (from inside the oral cavity) operations, with minimal health risks;
  • reconstructive and plastic stages of the surgery will restore the patient’s appearance and swallowing and chewing functions;
  • new radiotherapy options: very precise, non-damaging to organs and tissues surrounding the tumor, safe for the patient's health;
  • large Oncology Centers use proton therapy, which is the safest and most effective radiotherapy option for oropharyngeal tumors;
  • doctors working in the Departments of Oncology will treat the disease with the help of modern drugs: this is not only by chemotherapy, but also targeted therapy and immunotherapy.

To undergo treatment of oropharyngeal cancer in Germany, please use the Booking Health service. On our website you have the opportunity to get up-to-date and accurate information about the cost of treatment in Germany, compare prices in different German hospitals and book a medical care program at a favorable price. The treatment will be easier and quicker for you, and the cost of treatment in Germany will be lower.

You are welcome to leave your request on the Booking Health website. Our employee will contact you, consult with you, and answer all of your questions. We will take care of the organization of your trip abroad. We will provide the following benefits for you:

  • We will select the best German hospital, whose doctors specialize in the diagnosis and treatment of oropharyngeal cancer and achieve the best results.
  • We will help you to overcome the language barrier and establish your communication with the doctor at the German hospital.
  • The waiting time for the diagnosis and treatment will be reduced, and you will receive medical care on the most suitable dates for you.
  • We will reduce the price. The cost of treatment in Germany will be lower than usual due to the elimination of overpricing and coefficients for foreign patients.
  • Our specialists will solve any organizational issues: paperwork, transfers from the airport to the German hospital and back, hotel booking, and interpreting services.
  • We will prepare your documents and translate them into English or German. You do not have to repeat the previously performed diagnostic procedures.
  • We will stay in contact with the German hospital after the completion of your treatment.
  • We will arrange additional diagnosis and treatment, if required.
  • We will buy medicines in the other country and forward them to your native country.

While the best specialists in the world are taking care of your health, the Booking Health staff will help to reduce the cost of treatment in Germany and take care of all the travel arrangements.

 

Authors: 

The article was edited by medical experts, board-certified doctors Dr. Vadim Zhiliuk and Dr. Sergey Pashchenko. For the treatment of the conditions referred to in the article, you must consult a doctor; the information in the article is not intended for self-medication!

 

Sources:

European Society for Medical Oncology

Cancer Support Community

Medscape




Feedback of our customers from other resources

Need Help?

Thank you!

We received your treatment application in the best Europe clinics. Our manager will contact you within the next 24 hours.