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Parathyroid Adenoma Treatment

Cost for treatment

Diagnosis of parathyroid adenoma
1803
Surgical treatment of parathyroid adenoma
5801.51
General therapeutic rehabilitation
0.00

Hospital Neuperlach Munich

9.8/10
location_onGermany, Munich

Department of General, Abdominal, Endocrine and Colorectal Surgery

The Hospital Neuperlach Munich provides modern medical services of the highest quality. The medical center is an Academic Hospital of the Ludwig Maximilian University of Munich, and therefore it can offer its patients innovative diagnostic and therapeutic methods available only in the best German hospitals. The medical complex o
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11877.2

Marien Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of General and Abdominal Surgery, Colorectal Surgery, Endocrine Surgery and Hernia Surgery

The Marien Hospital Duesseldorf is a modern medical facility in the very center of Duesseldorf and a recognized Research Center. The foundation stone of the hospital was laid back in 1864 with the support of the Catholic Church. The Christian principles of helping and supporting patients have not changed at all over the years, b
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
8283.6

University Hospital Ulm

8.7/10
location_onGermany, Ulm

Department of General and Abdominal Surgery

The University Hospital Ulm started its activities 35 years ago and during this time it has become one of the most prestigious medical institutions in Europe. The hospital is famous for its numerous discoveries and the world-class achievements in medicine and pharmaceuticals. The medical facility has 29 specialized departments a
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11195.47

University Hospital Marburg UKGM

8.6/10
location_onGermany, Marburg

Department of Abdominal, Thoracic and Vascular Surgery

The University Hospital Marburg UKGM offers patients modern diagnostics and comprehensive therapy at the international level. As a maximum care hospital, the medical facility specializes in all fields of modern medicine ranging from ophthalmology to traumatology and dentistry. The main areas of specialization of the hospital are
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10314.34

University Hospital Carl Gustav Carus Dresden

9.1/10
location_onGermany, Dresden

Department of Abdominal and Colorectal Surgery, Hepatobiliary Surgery, Hernia Surgery, Bariatric Surgery, Endocrine Surgery, Thoracic and Vascular Surgery

According to the reputable Focus magazine, the University Hospital Carl Gustav Carus Dresden ranks among the top five German hospitals! The hospital is the benchmark for modern high-quality medicine. Positioning itself as a maximum care medical facility, the hospital represents all medical fields. There are 26 specialized depart
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
13611.29

University Hospital Frankfurt am Main

10/10

Department of General and Abdominal Surgery

According to the reputable Focus magazine, the University Hospital Frankfurt am Main ranks among the top German medical facilities! The hospital was founded in 1914 and today is a well-known German medical facility, which combines rich traditions and scientific innovations. A medical team of more than 6,500 employees cares about
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10526.27

University Hospital RWTH Aachen

9.2/10
location_onGermany, Aachen

Department of Adult and Pediatric General, Abdominal, Transplant Surgery

According to the prestigious Focus magazine, the University Hospital RWTH Aachen ranks among the top German hospitals! As a maximum care university medical facility, the hospital guarantees patients first-class medical services combined with a respectful and human attitude. The hospital integrates all the modern options for the
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11808.3

University Hospital Tuebingen

9.2/10
location_onGermany, Tuebingen

Department of General, Abdominal, Adult and Pediatric Transplant Surgery

According to the prestigious medical publication Focus, the University Hospital Tuebingen ranks among the top five German hospitals! The hospital was founded in 1805, therefore it is proud of its long history, unique experience, and outstanding achievements in the field of medical care, as well as research and teaching activitie
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11300.92

University Hospital Hamburg-Eppendorf

9.2/10
location_onGermany, Hamburg

Department of General, Abdominal and Thoracic Surgery

According to the Focus magazine, the University Hospital Hamburg-Eppendorf ranks among the top ten hospitals in Germany! Since its foundation in 1889, the hospital has taken a leading position in the European medical arena and still occupies it until today. A highly competent medical team of more than 11,000 employees takes care
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
13422.32

University Hospital Würzburg

9.2/10
location_onGermany, Würzburg

Department of General, Abdominal, Transplant, Vascular and Pediatric Surgery

According to the Focus magazine in 2019, the University Hospital Würzburg ranks among the top national German hospitals! The hospital is one of the oldest medical facilities in Germany. The centuries-old traditions of first-class treatment are combined with the very latest achievements of modern evidence-based medicine and
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10706.88

University Hospital Halle (Saale)

9.6/10
location_onGermany, Halle

Department of General, Abdominal, Vascular and Endocrine Surgery

According to the prestigious Focus magazine, the University Hospital Halle (Saale) ranks among the top German medical facilities! The history of the hospital has more than 300 years, and during this time it managed to earn an excellent reputation not only in Germany, but throughout the world. The hospital positions itself as a s
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10671.38

University Hospital Rechts der Isar Munich

9.8/10
location_onGermany, Munich

Department of Adult and Pediatric General, Abdominal, Hepatobiliary, Endocrine, Thoracic and Hernia Surgery

The University Hospital Rechts der Isar Munich was founded in 1834. It combines long traditions with the very latest advances in modern medicine. The medical facility includes 33 specialized departments and 20 interdisciplinary centers, where patients can receive top-class medical care in all medical fields. The hospital annuall
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11983.69

University Hospital Duesseldorf

9.5/10
location_onGermany, Duesseldorf

Department of General, Abdominal and Pediatric Surgery

According to the authoritative Focus magazine, the University Hospital Duesseldorf ranks among the top Germany hospitals! The hospital is an excellent example of a combination of high-quality health care, research and teaching activities. With more than 50,000 inpatients and about 300,000 outpatients every year, the hospital is
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11940.89

University Hospital Muenster

9.8/10
location_onGermany, Muenster

Department of General, Abdominal and Transplant Surgery

According to the Focus magazine, the University Hospital Muenster ranks among the top German hospitals! The hospital belongs to the most prestigious medical institutions in Germany. The hospital is distinguished by a high professionalism of its doctors, state-of-the-art technological equipment and the availability of the most ad
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10556.54

University Hospital Giessen UKGM

9.5/10
location_onGermany, Giessen

Department of General, Abdominal, Thoracic and Transplant Surgery

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
10227.68

University Hospital Erlangen

9.1/10
location_onGermany, Erlangen

Department of General, Abdominal, Endocrine, Colorectal and Bariatric Surgery

According to the Focus magazine, University Hospital Erlangen ranks among the best medical facilities in Germany! The hospital is one of the leading healthcare facilities in Bavaria and offers top-class medical care distinguished by the close intertwining of clinical activities with research and training of medical students. The
Diagnosis of parathyroid adenoma
0.00
Surgical treatment of parathyroid adenoma
11246.63
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About the disease

Parathyroid adenoma originates in parathyroid glands, which are located in the vicinity to the thyroid gland. Typically, person has two pairs of parathyroid glands, which are called upper and lower parts of the glands, but in some cases there may be an extra pair, if thyroid gland is thickened. Parathyroid glands are responsible for producing parathyroid hormone, which regulates the calcium metabolism in the body.

If a person is diagnosed with parathyroid cancer, his/her parathyroid glands accumulate too much hormone, which results in increase of calcium level in blood. Parathyroid adenoma is more common in women, who develop it twice as often as men. It can develop after 20 years of age. According to American medical site HealthLine, surgery for this disease is in 90% successful. 

This disease is caused by over abundant production of parathyroid hormone. It can also develop if gastrointestinal tract was damaged by hypercalcemia. Its most common manifestations are exacerbation, cholecystitis, pancreatitis which are accompanied by severe pain and vomiting.

Abnormalities in cardiovascular system can also cause parathyroid adenoma and they are usually expressed in arterial hypertension and dysfunction of coronary arteries.

Generally, people with hypercalcemia feel pain in the joints because they have unnecessary deposits of calcium salt in their bones. Their skin becomes dry and itchy, they start to lose hair and their mobility becomes restricted.

Symptoms

Ectopic parathyroid adenoma usually occurs if there was some kind of mutation in the production of parathyroid hormone. Mutation affects cells that are mostly responsible for the calcium transport from adenomas. Consequently mutated cells acquire an abnormal secretory activity, and they begin to multiply, transforming into malignant cells that develop parathyroid adenoma. Sometimes mutated cells do not become cancerous, but if the abnormality is not treated on time, risk of developing tumor becomes very high. Overall, typical symptoms are:

  • Dizziness
  • General loss of appetite
  • Evening nausea
  • Constipation
  • Pain in the bones
  • Muscle weakness
  • Memory loss
  • Depression
  • Convulsions
  • In rare cases coma

Almost all patients with parathyroid adenoma develop hypercalcemia in bones. That`s why patient with parathyroid adenoma experience osteoporosis, problems with vertebrae, loss of teeth and hair.  Excess of calcium deposits in the heart muscle causes myocardial infarction.

If hypercalcemia affects kidneys, patients may develop kidney stones, which are the cause of nephrocalcinosis.

Diagnosis

  • General laboratory tests can determine the amount of parathyroid hormone in blood. Such tests also assess level of calcium and phosphorus in the thyroid gland. In order to determine if there actually is a tumor in the gland, doctors use X-ray examination, ultrasound and biopsy.
  • In order to fully examine patient with parathyroid adenoma symptoms, doctor may refer to endocrinologist, gastroenterologist, cardiologist, nephrologist and neurologist to evaluate if hypercalcemia  is present in other organs.  .
  • To assess bone destruction severity doctor inspects the state of bones of the feet, hands, skull and torso. Condition of the digestive system is assessed by abdominal ultrasound or by endoscopy, when the camera is introduced into the patient's body.

Treatment

  • Parathyroid adenoma treatment usually requires surgical intervention with resection of the affected glands. In fact surgery is the only solution for this disease, because adenoma can not be cured by chemotherapy or radiofrequency intervention. During the surgery both sides of neck get opened, so that the doctor can remove adenoma. During the surgery on the parathyroid glands, it is important to constantly examine all glands, monitor calcium  in blood level and check heart activity.
  • Before the surgical intervention patient has to undergo special preoperative stage which includes treatment of hypercalcemia and organs that were affected by the excessive amount of calcium in the body. During this preoperative stage patient needs to be on a special diet, which totally restricts calcium consumption with food. Since surgery is done on the neck, it is vital for the surgeon to preserve patient's voice, which requires great skills and proficiency.
  • If there are multiple parathyroid adenomas they all need to be removed as well.

After parathyroid treatment, the levels of calcium in the body need to be checked constantly. Typically after the removal of adenomas the circulation of calcium in the blood normalizes in the matter of 3-4 days. In some rare cases patient may get hypocalcemia, which requires further treatment. Usually it can be cured by special diet and drugs that help to control level calcium. After the surgery the bone structure can become too fragile. In order to restore it, patients can take course of physiotherapy.

Authors: Dr. Nadezhda Ivanisova, Dr. Sergey Pashchenko