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University Hospital Essen

Essen, Germany


Department of Bone Marrow Transplantation


Dietrich W. Beelen

Prof. Dr. med.

Dietrich W. Beelen

Specialized in: bone marrow transplantation

Curriculum vitae keyboard_arrow_down
  • Honored for special merits in the field of bone marrow transplantation
  • Essen, 16.06.2014 - The hematologist and oncologist Prof. Dr. Dietrich W. Beelen from the University Hospital Essen (UK Essen) received a special award at the Annual General Meeting of the German Cancer Corporate e.V. (DKG) on Saturday, June 14, 2014 in Berlin : The specialists awarded him for his services in the field of bone marrow transplantation with the Karl Heinrich Bauer medal in 2014.
  • Since 1994, DKG has been providing these to physicians and scientists as recognition for outstanding achievements in cancer research.

Focus


The focus of inpatient healthcare is on allogeneic stem cell transplants in malignant and benign hematological system diseases, as well as the transplantation of patient-specific haematopoietic stem cells after myeloablative (ie irreversibly killing the bone marrow function) or intensity-reduced  pretreatment. The clinic has a special expertise in performing allogeneic stem cell transplants with partially tissue-compatible related or unrelated donors. The latter, with a share of more than 70%, are now the main contingent of the graft donor at the clinic. The clinic has its own production area for stem cell preparations and a transplantation coordination, which serves as a communication center for patients, donors, donor registers as well as for assigning facilities and coordinates the necessary organizational procedures for stem cell transplants.

Special consultation hours
Polyclinic of the Clinic for Bone marrow transplantation
 
Research

  • Multicentric therapy optimization studies in leukemia, lymphoma and multiple myeloma
  • Development and testing of new methods of conditioning therapy (including new cytostatics, radioimmunotherapy, helical tomotherapy)
  • Allogeneic stem cell transplantation in elderly patients
  • Allogeneic stem cell transplants with partially identical donors
  • Optimization of donor selection
  • Techniques of transplant modification
  • Adoptive cell therapy after allogeneic stem cell transplantation
  • Significance of molecular polymorphisms of congenital and acquired immunity in allogeneic stem cell transplantation 
  • Detection and therapy of molecular residual disease after allogeneic stem cell transplantation

The Department of Bone Marrow Transplantation at the Essen University Hospital is a separate medical institution of the West German Cancer Center (WTZE), which performs hematopoietic stem cell transplantation to treat primarily malignant, as well as benign diseases of the bone marrow and lymphatic system. The Department is headed by Prof. Dr. med. Dietrich W. Beelen, specialist in the field of internal medicine, hematology and internal oncology. The Department is the largest European health care facility, specializing in the allogeneic stem cell transplantation from related and unrelated donors. Since 2010, the Department has been an active center of the professional association for cancer cell therapy in North Rhine-Westphalia. 

The range of medical services of the Department of Bone Marrow Transplantation at the Essen University Hospital includes all aspects of patient care, research and academic teaching in the field of hematopoietic stem cell transplantation. The allogeneic stem cell transplantation for malignant and benign hematological systemic diseases makes up the main clinical and scientific focus of the Department. The main treatment focus is on acute and chronic leukemias, myelodysplastic syndromes, malignant tumors and aplastic syndromes.

One more focus of the Department under the direction of Prof. Dr. med. Dietrich W. Beelen is patient's own hematopoietic stem cell transplantation after myeloablative preliminary therapy (causing an irreversible disorder of the bone marrow).

The field of patient care offers all services from the determination of indications, consultations, preparation and inpatient treatment up to a long-term monitoring of patients by the medical staff of the Department. In addition to the specialized laboratory diagnosis, an integral part of the range of services of the Department of Bone Marrow Transplantation at the Essen University Hospital is the production of stem cell based drugs and other products for cell therapy. 

The Department of Bone Marrow Transplantation at the Essen University Hospital under the direction of Prof. Dr. med. Dietrich W. Beelen is part of the development program of the West German Cancer Center “Cancer Centers of Excellence”. It is involved in the German Consortium for Translational Cancer Research (DKTD), initiated by the Federal Ministry of Education and Research and the German Cancer Society. 

The focuses of the Department of Bone Marrow Transplantation at the Essen University Hospital are:

  • Allogeneic stem cell transplantation, including pediatric patients
  • Autologous stem cell transplantation, including pediatric patients
  • Follow-up care
  • Production of stem cell based drugs
  • Transplantation diagnosis



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