Department of Oncology, Hematology and Bone Marrow Transplantation - University Hospital of Ludwig Maximilian University of Munich
University Hospital of Ludwig Maximilian University of Munich
Munich, Germany
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Department id #
113765
Prof. Dr. Dr. Michael von Bergwelt
Department of Oncology, Hematology and Bone Marrow Transplantation
Specialized in: oncology, hematology, bone marrow transplantation About the Department of Oncology, Hematology and Bone Marrow Transplantation at University Hospital of Ludwig Maximilian University of Munich
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The Department of Oncology, Hematology and Bone Marrow Transplantation at the University Hospital of Ludwig Maximilian University of Munich provides the full range of diagnostic and therapeutic services to patients with malignant solid tumors, and benign and malignant blood pathologies. Of particular interest is the treatment of patients with acute leukemia, lymphomas, multiple myeloma, sarcomas, gastrointestinal cancer, lung cancer, breast cancer, and rare malignant tumors. The department is part of the Comprehensive Cancer Center Munich, thanks to which doctors from related specialties are involved in the therapeutic process. All modern diagnostic methods and therapeutic procedures are available here, including bone marrow transplantation, which is often the most effective treatment method for blood cancer. The health of patients is in the safe hands of a highly qualified medical team, consisting of 65 doctors and 130 nurses. The department treats about 2,800 inpatients and more than 10,000 outpatients every year. The department's specialists pay due attention to the psychological state of their patients diagnosed with cancer, so a program of psycho-oncological care is being successfully implemented here. The Head Physician of the department is Prof. Dr. Dr. Michael von Bergwelt.
Healthcare professionals in the field of oncology admit patients with various types of cancer. The department's team of doctors pays special attention to treating colon, stomach, esophageal, pancreatic, liver, bile duct, lung, and breast cancers, as well as bone and soft tissue sarcomas. Doctors are particularly skilled at treating rare malignant solid tumors, such as neuroendocrine tumors and cancers of unknown primary. Upon admission to the department, a patient undergoes diagnostic tests, based on the results of which oncologists, together with surgeons, radiation therapists, radiologists, and other specialists, develop the most effective treatment regimen. As a rule, it is practically impossible to do without surgery. Depending on the particular clinical case, a treatment regimen may also include chemotherapy, radiation therapy, antibody therapy, targeted therapy, hormonal therapy, or immunotherapy. The department's oncologists successfully use hyperthermia combined with chemotherapy to treat bone and soft tissue sarcomas. Hyperthermia improves the effectiveness of chemotherapy by increasing blood flow to the tumor, allowing chemotherapy agents to penetrate deeper into the neoplasm tissues. Psychological care is also an integral part of the therapeutic process, since it is very important to maintain a patient's positive attitude towards a successful treatment outcome in the fight against cancer.
The key focus of the hematology team is the treatment of patients with leukemias, lymphomas, and multiple myeloma. The specialists also treat benign blood diseases, such as anemia and hemoglobinuria. Chemotherapy is an indispensable method in the fight against blood cancer. The department's therapeutic options are, however, not limited to this type of treatment. The department is one of the few in Europe that offers an innovative form of immunotherapy called CAR T-cell therapy. The essence of the method is to harvest the patient's leukocytes and genetically program them to destroy cancer cells. Leukocytes are harvested with the use of special high-tech equipment, after which the resulting biological material is genetically modified. As a result of genetic manipulations, chimeric antigen receptors (CARs) appear on the surface of leukocytes. After the processing and multiplication of cells in the laboratory, they are administered into the patient's body by infusion. CAR T-cell therapy is highly effective and can cure even the most complex cases of blood cancer.
The department's spectrum of therapeutic services is complemented by a bone marrow transplant, which is often indicated for patients with advanced leukemias, lymphomas, and multiple myeloma. The department's specialists have been performing bone marrow transplantation procedures since 1979. The Section for Bone Marrow Transplantation has 24 beds, and thus this is the largest medical facility of this kind in Germany. Every year, more than 100 allogeneic bone marrow transplant procedures (transplantation of donor stem cells) are performed here. The department's transplantation success rate is one of the highest in Europe. This is not surprising, as the department employs professional doctors and has advanced technical resources.
The department specializes in the diagnostics and treatment of the following diseases:
Hematology |
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| Oncology |
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Other diseases |
The department's therapeutic options include:
- Chemotherapy
- Radiation therapy
- Antibody therapy
- Targeted therapy
- Hormone therapy
- Immunotherapy
- Hyperthermia combined with chemotherapy
- CAR-T cell therapy
- Bone marrow transplantation
- Other treatment methods
Curriculum vitae
Higher Education and Professional Career
- 1988 - 1996 Medical studies at the Universities of Freiburg, Muenster and Paris (University of Paris-South XI).
- 1996 Admission to medical practice.
- 1994 - 1996 Human Biology studies at the University of Paris-South XI.
- 1996 Master in Biological and Medical Sciences (MSBM, Maitrise de Sciences Biologiques et Medicales).
- 1996 Examination for the US medical license (USMLE), I and II Parts.
- 1997 Thesis, University of Freiburg. Subject: "Phenotypic and functional characteristics of lymphocyte infiltrating tumor in patients with colorectal carcinoma stimulated by interleukin-2 and interleukin-4 in vitro".
- 1997 - 1999 Internship, Department of Internal Medicine I.
- 1999 Board certification in Emergency Medicine, Lower Saxony.
- 1999 - 2002 Postdoctoral Fellow, Dana-Farber Cancer Institute, Harvard Medical School, Boston.
- 2002 Thesis for Dr. rer. nat., with honors, University of Oldenburg. Subject: "Biological and biotechnological analysis of antigen-presenting B cells activated by CD40".
- 2002 - 2007 Internship and Scholarship, Department of Internal Medicine I, University Hospital Cologne.
- 2003 - 2009 Head, Max Eder Junior Research Group, German Cancer Society.
- 2006 Board certification in Internal Medicine, Hematology and Oncology.
- 2007 Venia Legendi in Internal Medicine. Subject: "Analysis of the use of the antigen-presenting function of B cells for tumor immunotherapy".
- 2008 Board certification in Intensive Care.
- 2008 Director of the Cologne Interventional Immunology Project and Scientific Director of the Stem Cell Transplant Program.
- 2009 Board certification in Infectiology.
- 2011 Managing Senior Physician.
- 2012 Adjunct Professor in Internal Medicine, University of Cologne.
- 2012 Adjunct Professor and Head of Hematology Сourse, Ronald Finn Department of Experimental Medicine, University of Liverpool (rejection).
- 2015 CARTime Research Consortium (CAR T Cell Clinical Study in Melanoma), Research Coordinator from the German Federal Ministry of Education and Research (BMBF).
- 2016 Research Consortium of the German Cancer Society (DKH) "Inhibition of control points of the immune response in Hodgkin's lymphoma", Head of the Section of Tumor Immunology.
- Since 2017 Head of the Department of Oncology, Hematology and Bone Marrow Transplantation, University Hospital of Ludwig Maximilian University of Munich.
Prizes, Awards, Honors and Memberships
- 2015 Best Abstract Award from the German Society of Hematology and Oncology, DGHO (Co-Author).
- 2010 Travel Award from the American Society for Bone Marrow Transplantation.
- 2010 Basic Science Award (O84 Abstracts, Co-Author) from the European Society for Blood and Marrow Transplantation.
- 2002 Member of the Josep Carreras Leukaemia Foundation, Germany.
- 2001 Member of the American Lymphoma Research Foundation.
- 1999 Travel Award from the American Society of Hematology.
- 1999 EMSA Science Award, University of Prague.
- 1997 Mildred Scheel Foundation Fellow, German Cancer Society, University of Prague.
Photo of the doctor: (c) LMU Klinikum
