Glioblastoma diagnosis in University Hospital of Ludwig Maximilian University of Munich
University Hospital of Ludwig Maximilian University of Munich
Munich, Germany
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Program id #
150037
Prof. Dr. med. Christian Schichor
Department of Adult and Pediatric Neurosurgery, Spinal Surgery
Specialized in: adult and pediatric neurosurgery, spinal surgery The program includes:
- Initial presentation in the clinic
- clinical history taking
- review of medical records
- physical examination
- laboratory tests:
- complete blood count
- general urine analysis
- biochemical blood test
- inflammation markers (CRP, ESR)
- blood coagulation analysis (aPTT, PT, INR)
- neurological examination
- electrophysiology study (if indicated clinically)
- CT/ MRI of the brain and spine
(if indicated clinically, additional cost is 650/1200€) - biopsy with histological study
(if indicated clinically, additional cost is 2500€/stereotactic biopsy 7000) - nursing services
- consultation of related specialists, including specialists in
oncology and radiotherapy - treatment by chief physician and all leading experts
- developing of further guidance by specialists in oncology and radiotherapy
Required documents
- Medical records
- MRI/CT scan (not older than 3 months)
- Biopsy results (if available)
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About the department
The Department of Adult and Pediatric Neurosurgery, Spinal Surgery at the University Hospital of Ludwig Maximilian University of Munich offers the full range of diagnostic examinations and surgical treatment of diseases of the central and peripheral nervous systems. The team of the department's neurosurgeons successfully performs operations for pathologies of the brain and spinal cord, spine, neurovascular pathologies, pituitary diseases, and epilepsy. The doctors specialize in surgery for malignant brain tumors. The department is part of the Gliome Competence Center Network and the German Cancer Aid. The department uses the latest minimally invasive microsurgical techniques, navigation systems, intraoperative systems, and other advanced technical resources that allow for an optimal therapy result. The department has 84 beds for its patients, 10 of which are intended for intensive care. Medical care is based on an individual approach with due consideration of the patient's specific clinical data and needs. The specialists working at the medical facility always devote enough time to personal communication with their patients and do everything possible so that they receive effective treatment and maintain a decent quality of life. The Head Physician of the department is Prof. Dr. med. Christian Schichor.
The department effectively treats benign and malignant brain tumors. The department has the status of a certified Neuro-Oncology Center of the German Cancer Society (DKG), which is part of the Comprehensive Cancer Center Munich. The specialists most often deal with such types of tumors as gliomas, meningiomas, neuroblastomas, hemangioblastomas, and brain lymphomas. Neurosurgeons also have vast experience in treating brain metastases caused by other malignant tumors, such as lung or breast cancer.
If a brain tumor is suspected, the diagnostic protocol includes a mandatory head magnetic resonance imaging (MRI). In some cases, positron emission tomography (PET) can also be performed. A stereotactic biopsy can be performed for a follow-up histological examination of the material obtained and the establishment of a final diagnosis. A treatment regimen is developed for each patient individually at weekly tumor boards, in which doctors from related medical specialties also participate. When choosing the optimal therapeutic methods, doctors take into account the type of brain tumor, its location, growth rate, clinical symptoms, and a patient's general health condition. In almost all cases of brain cancer, patients require a tumor resection surgery if the clinical case allows for this type of treatment (some tumors in hard-to-reach places cannot be surgically resected). The department's neurosurgeons work in well-equipped operating rooms with the possibility to use advanced surgical microscopes, neuronavigation, intraoperative neuromonitoring, intraoperative imaging using fluorescence methods (ALA and ICG), intraoperative CT scans, and other technical resources, which ensure the most effective and safe surgical treatment at the same time. The department is also one of the few in Germany offering such innovative brain cancer treatment methods as interstitial brachytherapy (stereotactic treatment) and photodynamic therapy (experimental treatment). When treating brain cancer, conservative methods such as chemotherapy, radiation therapy, symptomatic treatment, maintenance therapy, and others are widely used.
The department's neurosurgeons have been successfully performing surgical treatment for epilepsy in a highly specialized center for many years. The patients with this pathology are managed in close cooperation with neurologists, including pediatric neurologists, specialists in nuclear medicine, neuroradiology, and psychiatry. In most cases, patients with epilepsy are treated effectively with drug therapy, and surgery is not required. Nonetheless, there are cases when surgery is the only way to provide a patient with a decent quality of life. The operation is preceded by comprehensive diagnostics to assess the advisability of its performance. A diagnostic protocol may include such tests as electroencephalographic monitoring during and between epileptic seizures, seizure semiology assessment, invasive EEG monitoring, tractography, MRI scans, including functional ones, 18F-FDG PET/CT scans, SPECT, and others. The upcoming epilepsy surgery is 3D planned based on the diagnostic data obtained. The essence of the operation is to remove or isolate a part of the brain in which electrical activity is disturbed. For patients with bilateral or multifocal epilepsy, classical surgery is contraindicated, and therefore they undergo vagus nerve electrical stimulation. A thalamic stimulator implantation surgery may be performed as an alternative treatment. The success rate of epilepsy surgery in the medical facility reaches 80%, which is one of the best rates in all of Europe.
The department also provides top-class surgical services for patients with spinal diseases. Degenerative compression syndromes of the nerve roots and spinal cord caused by spinal disc herniation, spinal stenosis, and segmental instability (slipped vertebrae or spondylolisthesis) are the most common in the clinical practice of neurosurgeons. Other common pathologies are chronic back pain, spinal fractures, spine and spinal cord tumors, and spinal dysraphia. The department's team of specialists perform sparing microsurgical and minimally invasive interventions, stabilizing surgery, intervertebral disc replacement surgery, and CT-guided blocks. During spinal surgery, advanced neuronavigation and intraoperative monitoring systems are used, thanks to which patients receive highly effective and maximally safe treatment.
An important place in the department's clinical activities is given to treating children with brain and spinal cord tumors, cleft skull base and spina bifida, epilepsy, hydrocephalus, traumatic brain injuries, spinal injuries, arachnoid cysts, vascular malformations, spasticity, and other pathologies. When performing operations on children, the department's neurosurgeons also use the latest technologies, including surgical microscopes, neuronavigation, neuromonitoring, and endoscopic equipment.
The department's range of medical services includes the following:
- Surgical treatment of tumors of the brain and spinal cord, meninges and peripheral nerves in adults and children
- Brain and spinal cord tumors (all types of gliomas, glioblastomas, and pilocytic astrocytomas)
- Brain and spinal cord metastases due to various cancers
- Epineural tumors (neurinomas/schwannomas)
- Tumors of the brain and spinal cord meninges (meningiomas)
- Microsurgical tumor resection with the fluorescent dye 5-ALA
- Resection with modern methods of intraoperative neuronavigation and with various imaging techniques
- Stereotactic brachytherapy with the implantation of radioactive iodine-125 seeds (for gliomas and metastases)
- Photodynamic therapy with stereotactic methods for malignant glioma recurrences
- Stereotactic treatment of brain tumors in children
- Stereotactic cyst puncture, especially in the case of cystic craniopharyngiomas, with the implantation of "internal shunts"
- Stereotactic-guided ventriculocisternostomy in the case of hydrocephalus caused by tumors
- Skull base surgery
- Acoustic neuromas
- Meningiomas
- Chordomas
- Epidermoid cysts
- Minimally invasive surgery
- Classic open surgery
- Surgical treatment of neurovascular diseases
- Aneurysms
- Dural arteriovenous fistulas
- Arteriovenous malformations
- Cavernomas
- Bleeding in the brain
- Stroke
- Endovascular procedures
- Surgical treatment
- Radiosurgical techniques
- Spinal surgery
- Degenerative compression syndromes of the nerve roots and spinal cord caused by spinal disc herniation, spinal stenosis, and segmental instability (slipped vertebrae or spondylolisthesis)
- Chronic pain in the neck and back, and facet syndrome
- Traumatic spinal injuries (fractures)
- Spine and spinal cord tumors
- Spinal dystrophic syndromes and malformations
- Microsurgical minimally invasive decompression surgery (for example, interlaminar fenestration, foraminotomy, and crossed laminectomy)
- Stabilizing interventions on all segments of the spine using neuronavigation and intraoperative computed tomography
- Facet joint block and facet joint cryotherapy under CT guidance
- Removal of tumors of the vertebral bodies, spinal canal and spinal cord using intraoperative electrophysiological monitoring of nerve ending functions
- Intervertebral disc replacement surgery
- Surgical treatment of spinal cord tumors
- Neuromas
- Meningiomas
- Ependymomas
- Astrocytomas
- Hemilaminectomy (small lateral tumors)
- Laminectomy (small medial tumors)
- Laminoplasty
- Functional neurosurgery
- Uncontrolled pain syndromes
- Movement disorders
- Spasticity
- Ablative techniques
- Intrathecal administration of drugs using a catheter or a special pump
- Therapeutic electrical stimulation of the central nervous structures
- Microsurgical vascular decompression in the case of paroxysmal extreme pain disorder
- Deep brain stimulation (for tremor, dystonia, and Parkinson's disease)
- Surgical treatment of epilepsy
- Partial resection of the anterior part of the temporal lobe
- Cerebral cortex electrical stimulation
- Vagus nerve electrical stimulation
- Thalamic stimulator implantation surgery
- Surgical treatment of diseases of the nervous system in children
- Brain and spinal cord tumors
- Spina bifida and cleft skull base
- Epilepsy
- Hydrocephalus
- Vascular malformations
- Craniosynostosis
- Spasticity (for example, dystonia)
- Traumatic brain injuries and spinal fractures
- Arachnoid cysts
- Arnold-Chiari malformation
- Microsurgical interventions
- Minimally invasive interventions, including operations with neuronavigation and neuromonitoring
- Endoscopic interventions
- Surgical treatment of pituitary tumors
- Pituitary adenoma
- Craniopharyngioma
- Rare pituitary tumors
- Microsurgical interventions
- Endoscopic interventions
- Stereotactic irradiation with the CyberKnife system (in rare cases)
- Surgical treatment of peripheral nerve diseases
- Carpal tunnel syndrome
- Cubital tunnel syndrome
- Radial tunnel syndrome
- Scalene myofascial pain syndrome
- Meralgia paresthetica
- Tarsal tunnel syndrome
- Microsurgical operations
- Surgical treatment of other diseases of the central and peripheral nervous systems
Curriculum vitae
Higher Education and Postgraduate Training
- 1988 - 1990 Medical studies, University of Regensburg.
- 1990 - 1995 Medical studies and state exam, University of Wuerzburg.
- 01.2003 Thesis defense, Ludwig Maximilian University of Munich.
- 01.2013 Habilitation and PD, Ludwig Maximilian University of Munich.
- 2014 - 2016 Master of Health Business Administration (MHBA), Health Economics, Friedrich-Alexander University of Erlangen-Nuremberg.
- 02.2019 Extraordinary Professorship, Ludwig Maximilian University of Munich.
Professional Career
- 04.2007 - 04.2009 Senior Physician, Department of Adult and Pediatric Neurosurgery, Spinal Surgery at the University Hospital of Ludwig Maximilian University of Munich.
- Since 05.2009 Deputy Head and Managing Senior Physician, Department of Adult and Pediatric Neurosurgery, Spinal Surgery at the University Hospital of Ludwig Maximilian University of Munich.
- Acting Head of the Department of Adult and Pediatric Neurosurgery, Spinal Surgery at the University Hospital of Ludwig Maximilian University of Munich.
Clinical Interests
- Treatment of cerebrovascular diseases.
- Treatment of skull base tumors.
- Treatment of orbital tumors.
Photo of the doctor: (c) LMU Klinikum
About hospital
According to the Focus magazine, the University Hospital of Ludwig Maximilian University of Munich is regularly ranked among the best medical institutions in Germany!
The hospital is the largest multidisciplinary medical facility, as well as a leading research and training center in Germany and Europe. The hospital is proud of its bicentenary history and tirelessly confirms its primacy at the national and international levels. The outstanding quality of medical care is complemented by highly productive research activities, thanks to which many effective diagnostic and therapeutic methods, saving people’s lives, have been presented in medical practice.
The medical facility includes two main buildings, Grosshadern and Innenstadt. The hospital has 29 specialized departments, 53 interdisciplinary centers, 11 institutes, and many sections. More than 500,000 patients are treated here every year, which indicates the hospital's excellent reputation. A large and highly professional medical team, consisting of 1,800 doctors and 3,300 nursing staff, works for the benefit of patients. The hospital has 2,000 beds to accommodate patients.
The hospital's infrastructure deserves special attention: advanced diagnostic equipment that allows doctors to detect the slightest pathological changes in the human body, the latest operating rooms with highly efficient monitoring systems, robot-assisted surgical systems that facilitate sparing operations, and proper postoperative care.
Excellent technical resources and highly professional medical staff are undoubtedly the hospital's pride, but the medical facility also pays attention to the patient's comfort and to a humane attitude toward their life situation. When providing the necessary medical care, doctors and nursing staff always show a friendly attitude, inform patients in detail about the upcoming diagnostic and therapeutic procedures, gladly answer all questions of interest to patients, and provide moral support during the therapeutic process.
The hospital has many prestigious quality certificates, including a DIN EN ISO 9001 certificate, an IQM certificate, an endoCert certificate, certificates from the German Cancer Society (DKG) for treating various types of cancer, the German Cardiac Society (DGK), the German Society for Orthopedics and Trauma Surgery (DGOU), etc. Thus, patients can count on the best possible treatment outcome due to the use of the most effective and, at the same time, sparing therapeutic techniques.
Photo: (с) depositphotos
Accommodation in hospital
Patients rooms
The patients of the University Hospital of Ludwig Maximilian University of Munich live in comfortable, spacious, single and double patient rooms with a modern design. Each room is equipped with an ensuite bathroom with a shower and toilet. The furnishing of a standard patient room includes a comfortable bed, the position of which can be adjusted using the remote control, a locker for storing personal belongings, a TV, and a telephone. Also, if desired, you can connect to the Internet. In addition, patients can opt for enhanced-comfort rooms, with a safe, a fridge, and upholstered furniture.
The hospital has an excellent infrastructure. The medical facility’s area houses a bank, ATMs, a hairdresser, shops with a wide range of food, drinks, newspapers, magazines, and personal hygiene items, play areas for children, and a beautiful garden for walking, etc.
Meals and Menus
The patient and his accompanying person are offered a daily choice of three menus, including a vegetarian one. If you are on a specific diet for any reason, you will be offered an individual menu. Please inform the medical staff about your dietary preferences prior to the treatment.
Further details
Standard rooms include:
Toilet
Shower
Wi-Fi
TV
Religion
Religious services are available upon request.
Accompanying person
Your accompanying person may stay with you in your room or at a hotel of your choice during the fixed program.
Hotel
You may stay at a hotel of your choice during an outpatient program. Our managers will help you to choose the best option.
The hospital offers a full range of laboratory tests (general, hormonal, tests for infections, antibodies, tumor markers, etc.), genetic tests, various modifications of ultrasound scans, CT scans, MRI and PET/CT, angiography, myelography, biopsies, and other examinations. Treatment with medications, endoscopic and robotic operations, and stereotaxic interventions are carried out here, modern types of radiation therapy are also used. The hospital offers patients all the necessary therapeutic techniques.
- Allogeneic bone marrow transplantation
- Microsurgical transplantation of head and neck tissues
- Microsurgical resection of brain tumors with intraoperative fluorescence
- Minimally invasive treatment of spine pathologies
- Joint replacement with postoperative rehabilitation (fast track program)
Patients with benign and malignant neoplasms of various localizations, pathologies of arteries and veins, herniated discs, osteoporosis, congenital and acquired pathologies of the musculoskeletal system, benign and malignant pathologies of the mammary gland, and other pathologies.
Which specialties of the University Hospital of Ludwig Maximilian University of Munich are the best?
- Interventional and diagnostic neuroradiology
- Vascular surgery
- Cardiac surgery
- Mammalogy
- Gastroenterology and hepatology
Over 1,700 highly qualified doctors work at the hospital.
