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In vitro fertilization (IVF) long protocol (185823) | PAN Clinic Cologne - BookingHealth
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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. 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Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.<\/p>\n\n<p style=\"text-align: justify;\">The <strong>reproductologist <\/strong>will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.<\/p>\n\n<p style=\"text-align: justify;\">For your convenience, we offer <strong>hotels or apartments<\/strong> within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Stages of treatment<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\"><strong>Blockage<\/strong>. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Ovarian stimulation<\/strong>. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.<\/p>\n\n<p style=\"text-align: justify;\">The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Egg collection<\/strong>.&nbsp;In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men &ndash; the ICSI procedure).<\/p>\n\n<p style=\"text-align: justify;\"><strong>Fertilization<\/strong>. 2-6 hours after egg collection, eggs are fertilized with the husband&rsquo;s sperm. This is a laboratory procedure and no patient involvement is required.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo culture<\/strong>. Fertilized eggs will be cultured for 1-5 days. According to patients&rsquo; needs and embryo status, best 1-3 embryos can be transferred to the womb.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Preimplantation genetic diagnosis<\/strong>. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Embryo transfer<\/strong>.&nbsp;This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Pregnancy test<\/strong>. This test can be done 14 days after the embryo transfer.<\/p>\n\n<p style=\"text-align: justify;\"><u><strong>Service support<\/strong><\/u><\/p>\n\n<p style=\"text-align: justify;\">We fully support your trip, regardless of the chosen program. 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In vitro fertilization (IVF) long protocol in PAN Clinic Cologne

PAN Clinic Cologne

Cologne, Germany
Program id # 185823
Doctor photo
Dr. med. Stefan Palm
Department of Reproductive Medicine
Specialized in: reproductive medicine
Specialization Curriculum vitae

The program includes:

  • Initial presentation in the clinic
  • Case history taking
  • Review of medical records
  • General physical examination
  • Laboratory tests: 
    • Complete blood count 
    • General urine test
    • Biochemical blood test
    • Inflammation markers
    • Blood coagulation test 
    • Immune status
    • Analysis for infections
    • Hormone levels:
      • FSH
      • LH
      • Androgens
      • Progesterone
      • Prolactin
      • TSH-basal, fT3, fT4 
  • Ultrasound examination of abdomen and small pelvic organs 
  • Transvaginal ultrasound examination
  • Gynecological examination
  • Examination of the men:
    • Spermogram
    • Urethral smear analysis
    • Tests for infections
  • Hormonal stimulation 
  • In vitro fertilization (IVF)
  • Nursing services
  • Consultation of related specialists
  • Treatment by head doctor and all leading experts
  • Explanation of the individual treatment plan

All aspects of the program can be discussed with a medical advisor.

How program is carried out

You arrive in the hospital on the 19th day of the menstrual cycle. Our service starts at the airport. Our employee meets you at the airport and holds a sign with your name. In the individual folder you will find detailed information about the program.

The reproductologist will start from the general examination, you will undergo a number of laboratory and instrumental tests. After that, the doctor will elaborate an individual treatment plan, determine the drug dosages. You will receive a detailed explanation of all the procedures and will be able to contact your doctor for advice at any time.

For your convenience, we offer hotels or apartments within walking distance of the hospital. After the first appointment, you will have free time to rest. You can take the prescribed medications on your own or in the hospital. Also, several times, on the appointed days, it will be necessary to have an ultrasound examination (up to 3 times).

Stages of treatment

Blockage. On days 20-21 of the menstrual cycle, the pituitary gland is blocked with GnRH agonists. The purpose of the drug administration is to suppress ovarian function and stimulate maturation of more oocytes.

Ovarian stimulation. On the 2-4th day of the menstrual cycle, active stimulation of the ovaries with gonadotropins under constant ultrasound monitoring begins. It takes 10-14 days on average. An ultrasound examination is required to assess follicular growth. When the follicle is mature enough, a trigger injection is given.

The doctor will appoint the day of visiting the clinic. The time of oocyte collection (puncture) is determined. 36 hours before the puncture, a woman makes a stimulating (trigger) injection of hCG (human chorionic gonadotropin).

Egg collection. In the hospital, the follicles are punctured with the collection of mature eggs (on the 12-15 day of the menstrual cycle). The husband of the patient, on his turn, collects the ejaculate. The ejaculate can be collected naturally, or by a puncture of the testicle (in azoospermia, obstruction of the vas deferens in men – the ICSI procedure).

Fertilization. 2-6 hours after egg collection, eggs are fertilized with the husband’s sperm. This is a laboratory procedure and no patient involvement is required.

Embryo culture. Fertilized eggs will be cultured for 1-5 days. According to patients’ needs and embryo status, best 1-3 embryos can be transferred to the womb.

Preimplantation genetic diagnosis. PGD is usually performed on day 3. It takes 1 day to receive the results. One or two cells from the embryo can be taken without harming it, and some genetic tests can be done in one or two days.

Embryo transfer. This procedure is painless and no anesthesia is required, although some patients need sedation. One hour after the procedure, patients can leave the clinic and can return home on the same day.

Pregnancy test. This test can be done 14 days after the embryo transfer.

Service support

We fully support your trip, regardless of the chosen program. We provide an individual medical coordinator and interpreter, help with choosing and booking a hotel, booking tickets, preparing medical reports.

Required documents

  • Medical records
  • Results of hormone blood tests (if available)
  • Pelvic ultrasoud (if available)

Service

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About the department

The Department of Reproductive Medicine at the PAN Clinic Cologne offers the full range of high quality medical services in the area of its competence. The department's specialists provide highly effective infertility treatment using the very latest medical advances. The department employs an experienced multidisciplinary team of doctors consisting of reproductive specialists, endocrinologists, gynecologists, andrologists, geneticists, biologists, nutritionists and psychologists. With over 30 years of clinical experience, the department's medical team cures infertility even in cases which are considered hopeless in many medical centers around the world. The department is distinguished by its exceptional competence in the field of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). The department's doctors pay special attention to the psychological aspect, since infertility often causes depression and apathy in women. Therefore, the department's competent psychologists work with patients. In addition, the department's doctors are always ready for personal communication with their patients, which favorably affect treatment outcomes. The main task of the doctors of the medical facility is to help women to сonceive a child and give her the joy of motherhood.The Chief Physician of the department is Dr. med. Stefan Palm.

As of today, the most effective and widespread method of infertility treatment is in vitro fertilization. The department's doctors have been performing IVF procedures for many years, demonstrating high treatment success rates. In vitro fertilization takes place in several stages. The main ones include superovulation stimulation, follicular puncture, direct artificial insemination (in the laboratory), embryo transfer into the uterine cavity and a pregnancy test. Obviously, prior to in vitro fertilization, the department's specialists carry out comprehensive diagnostics of both partners in order to detect the causes of infertility. After the diagnostics, the specialists assess the effectiveness of possible treatment options and, in particular, of the IVF procedure. Unfortunately, not all women get pregnant after the very first IVF procedure, so they need a second one. It should be noted that a woman's age also plays a key role in the success of in vitro fertilization for fertility treatment. It has been proven that the chances of conceiving a child with IVF in women under the age of 40 are significantly higher than in women after 40.

The department's medical team often combines IVF with intracytoplasmic sperm injection (ICSI). This method involves the introduction of a sperm cell into the cytoplasm of a mature egg for its fertilization. The doctors of the medical facility believe that the use of IVF in combination with ICSI is most preferable in case of insufficient sperm count in a partner or its reduced mobility. Such a combination of assisted reproductive technologies is often used if a woman is unable to conceive a child using the classic IVF protocol. During the ICSI procedure, the selected sperm is injected into the egg cell using the finest pipette. This makes the fertilization process as easy as possible. The resulting embryos are cultured in the laboratory for 3-5 days, and then transferred into the uterine cavity of the expectant mother. The department also offers TESE (testicular sperm extraction) technique. It is used for azoospermia or anejaculation.

The department carries out preimplantation genetic diagnosis, which allows the doctors to detect chromosomal abnormalities in an embryo before transferring it into the uterine cavity. This diagnostic examination in IVF allows the doctors to prevent the transmission of certain hereditary diseases to the unborn child, as well as miscarriage. This type of diagnosis can also be necessary for the couples without infertility, but with genetic diseases or a history of recurrent miscarriage.

The department's diagnostic and therapeutic options include:

  • Diagnostic procedures in women
    • Hormonal tests
    • Assessment of the fallopian tube condition
    • Diagnostic procedures to exclude endometriosis and benign neoplasms, which can prevent pregnancy
    • Diagnostic procedures to exclude malformations of the uterus, fallopian tubes and ovaries
    • Diagnostics of metabolic disorders in case of excess body weight and obesity
    • Diagnostic procedures to detect genetic disorders, which can prevent pregnancy (such as aneuploidy)
  • Diagnostic procedures in men
    • Diagnostic procedures to assess sperm quality
    • Diagnostic procedures to exclude ejaculatory duct obstruction
    • Diagnostic procedures to exclude bladder dysfunction causing retrograde ejaculation
    • Diagnostic procedures to exclude immunological infertility
  • Preimplantation genetic diagnosis
  • Diagnostics and counseling for women with recurrent miscarriage
  • Therapeutic procedures for fertility treatment 
    • Assisted reproductive technologies
      • Ovarian stimulation
      • Intrauterine insemination
      • In vitro fertilization
      • Intracytoplasmic sperm injection (ICSI)
      • Testicular sperm extraction (TESE)
    • Cryopreservation of eggs and sperm, ovarian and testicular tissues
    • Surgical treatment of female infertility factors (for example, endometriosis, fallopian tube obstruction, etc.)
  • Other medical services

Curriculum vitae

Higher Education and Professional Career

  • 1967 - 1972 Study of Human Medicine, Ludwig Maximilian University of Munich.
  • December 1972 State Medical Examination and Doctoral Thesis Defense, Ludwig Maximilian University of Munich.
  • 1973 Assistant Physician at the Hospital in Munich.
  • December 1973 Admission to medical practice.
  • 1974 - 1976 Research Fellow, Section of Clinical Chemistry and Biochemistry, Department of Surgery at the University Hospital Innenstadt.
  • 1976 - 1977 Scholarship of the German Research Foundation, C.S. Mott Center for Human Growth and Development at Wayne State University in Detroit, USA.
  • 1977 - 1988 Research Fellow, Department of Gynecology at the University Hospital of Ludwig Maximilian University of Munich.
  • Since 1981 Member of the Working Group on In Vitro Fertilization, focus on the follicular microenvironment and in vitro fertilization (funded by the German Research Foundation).
  • 1984 Board Certification in Gynecology and Obstetrics.
  • 1988 Foundation of the Center for Gynecological Endocrinology and Reproductive Medicine as part of the Haubrichforum Joint Medical Practice, Cologne.
  • 1989 - 1991 Head of the Haubrichforum Joint Medical Practice, Cologne.
  • 1989 Authorized to conduct advanced training courses in Obstetrics and Gynecology.
  • 1997 Optional retraining in Gynecological Endocrinology and Reproductive Medicine, as well as the theoretical foundations of the specialty "Laboratory research in obstetrics and gynecology".
  • 1999 Foundation of the PAN Clinic Cologne and the Interdisciplinary Center for Gynecological Endocrinology and Reproductive Medicine.
  • 1999 Chief Physician of the Department of Reproductive Medicine at the PAN Clinic Cologne.
  • 2002 Foundation of the PAN Institute of Endocrinology and Reproductive Medicine.
  • 2002 Permission to conduct advanced training courses in Gynecological Endocrinology and Reproductive Medicine at the PAN Clinic Cologne.
  • November 2006 Department of Reproductive Medicine at the PAN Clinic Cologne, received permission from the Medical Association of North Rhine-Westphalia to conduct advanced training courses.

Memberships in Professional Societies

  • Professional Association of Gynecologists.
  • German Society for Gynecology and Obstetrics.
  • Federal Union of Reproductive Medicine Centers of Germany.
  • German Society for Reproductive Medicine.
  • European Society of Human Reproduction and Embryology.
  • European Society for Gynecological Endoscopy.
  • American Society for Reproductive Medicine.
  • International Society for the Study of the Aging Male.
  • North Rhine-Westphalian Working Group on Reproductive Medicine.

Photo of the doctor: (c) PAN Klinik

About hospital

The PAN Clinic Cologne is a multidisciplinary medical facility that combines advanced medicine, excellent quality of patient care and a high level of comfort. Founded in 1999, the clinic is located in the very heart of Cologne. During this time, the medical complex has gained long clinical experience, but at the same time it has preserved its primary concept of medical care – high-quality diagnostics and treatment using the achievements of modern medicine. 

Today, a huge team of doctors at the clinic admits patients in 25 medical fields, including neurosurgery, neurology, orthopedics, cardiology, gynecology, mammology, urology, endocrinology, plastic surgery, etc. It is worth noting that the clinic employs the best specialists with a wealth of experience and thorough clinical training in the best medical facilities in Germany, other countries of Europe and USA. The clinic's medical team includes many professors who are distinguished by outstanding achievements in the treatment of diseases of a particular profile and who successfully conduct research activities, participate in national and international congresses, symposia and other events.

The clinic annually provides treatment to more than 10,000 patients, and more than 3,000 interventions of varying complexity are performed in its operating rooms. The operating theaters have state-of-the-art technology and equipment for classical open surgery and minimally invasive interventions. In addition, all departments of the medical facility have advanced diagnostic equipment, so that doctors always make the correct diagnosis, which determines the success of subsequent treatment. During the therapeutic process, the specialists strive to choose the most sparing, but at the same time highly effective treatment regimen.

The quality of medical services provided in the clinic is awarded with the prestigious DIN ISO 9001 certification, and therefore patients trust their health to doctors with complete confidence and benefit from the optimal treatment of the European standard.

Photo: (с) PAN Klinik, (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the PAN Clinic Cologne live in light and cozy rooms with a modern design. A standard patient room includes a comfortable automatically adjustable bed, a bedside table, an air conditioning, a DVD player, a telephone, a TV and a nurse call system. The patient rooms also have Wi-Fi. Each patient room has an ensuite bathroom with shower and toilet. The bathroom also has a hairdryer and towels.

If desired, the patients can live in enhanced-comfort rooms. These patient rooms are distinguished by their more exclusive interiors, as well as beautiful views of the Cologne Cathedral and cityscapes. The bathrooms in these enhanced-comfort facilities include disposable slippers, a bathrobe, towels and toiletries. In addition, the patients living in enhanced-comfort rooms are offered a special menu.

Meals and Menus

The patient and his accompanying person are offered tasty and balanced three meals a day: buffet style breakfast and dinner, as well as lunch consisting of 3-4 courses. If for some reason you do not eat all the foods, you will be offered an individual menu. Please inform the medical staff about your dietary preferences prior to treatment.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Religion

The religious services are available upon request.

Accompanying person

During the inpatient program, the accompanying person can live with the patient in a patient room or a hotel of his choice. Our managers will help you choose the most suitable option.

Hotel

During the outpatient program, the patient can stay at the hotel of his choice. Our managers will help you choose the most suitable option.