Diagnostic of Cholangiocarcinoma (Klatskin Tumor)
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Department of General, Abdominal Surgery and Surgical Oncology
The Department of General, Abdominal Surgery and Surgical Oncology offers the full range of services in these medical fields. Whenever possible, operations are performed using minimally invasive techniques, which are the gold standard of modern surgery. The outstanding quality of medical care is confirmed by numerous prestigious certificates, including certificates from the German Cancer Society, the German Hernia Society, etc. In addition, the department provides innovative hyperthermic intraperitoneal chemotherapy (HIPEC), which is available only in the most progressive clinics in Europe.
Department of General and Abdominal Surgery, Colorectal Surgery, Hepatopancreatobiliary Surgery, Hernia Surgery and Bariatric Surgery
The Department of General and Abdominal Surgery, Colorectal Surgery, Hepatopancreatobiliary Surgery, Hernia Surgery and Bariatric Surgery provides the full range of surgical treatment in its field of competence. The department's highly qualified surgeons annually perform about 2,000 surgical interventions. Extensive clinical experience allows the specialists to perform even particularly complex operations. The department’s advanced operating rooms serve for surgery to treat gastrointestinal diseases, liver, gallbladder, bile duct, pancreatic, rectal, anal and colon pathologies. The medical facility also successfully performs operations to treat hernias: inguinal, umbilical, and anterior abdominal wall hernias. In addition, the department's doctors deal with the surgical treatment of morbid obesity. Minor traumatic laparoscopic interventions are considered the gold standard, which guarantee a patient minimal risks and rapid postoperative restoration. Surgeons tell the patient in detail about their upcoming treatment and, in every possible way, support them in their recovery.
Department of General and Abdominal Surgery, Colorectal Surgery, Endocrine Surgery and Hernia Surgery
The Department of General and Abdominal Surgery, Colorectal Surgery, Endocrine Surgery and Hernia Surgery offers the full range of modern surgical interventions in the areas of its specialization. Every year, the medical facility performs more than 2,500 surgical interventions on an inpatient and outpatient basis. The department has vast clinical experience in the field of minimally invasive surgery, which allows the patient to avoid severe pain and prolonged hospitalization. In addition, the department offers robotic surgery using the most modern models of the da Vinci surgical system. The medical facility has the status of the Reference Center for Minimally Invasive Surgery and Hernia Surgery. Surgical treatment of cancer is one of the department's clinical priority focuses. A large number of da Vinci robot-assisted interventions are performed here for gastrointestinal cancers. The department holds a leading position in the use of the da Vinci surgical system in the treatment of rectal and sigmoid cancer patients. The operating rooms of the medical facility are equipped with the very latest technology, while hygiene and safety standards are at the highest level as well. Prior to surgery, the patient undergoes a comprehensive examination. Doctors also assess the risks of the upcoming operation and its expected results. With appropriate clinical indications, preference is always given to minimally invasive surgery.
University Hospital of Ludwig Maximilian University of Munich
Department of General, Abdominal, Transplant, Hepatopancreatobiliary, Colorectal, Endocrine, Bariatric Surgery and Hernia Surgery
The Department of General, Abdominal, Transplant, Hepatopancreatobiliary, Colorectal, Endocrine, Bariatric Surgery and Hernia Surgery provides the full range of services in the areas of its specialization and holds a leading position at the national and international levels in terms of the number of surgical interventions performed and their success. Of particular interest are operations for treating diseases of the bowel, stomach, esophagus, pancreas, liver, gallbladder, and bile ducts, and endocrine glands. The department's doctors have excellent skills in the surgical treatment of cancer, surgery for liver, kidney, pancreas, and small intestine transplants, and operations for morbid obesity. The department's operating rooms are the pride of the medical facility, since they have all the necessary technical options for performing operations with the da Vinci surgical system, image-guided interventions, and endoscopic surgical procedures, which are characterized by minimal trauma rates.
Department of General, Abdominal and Vascular Surgery
According to the Focus magazine, the Department of General, Abdominal and Vascular Surgery ranks among the top German medical facilities specializing in the treatment of bowel and lung cancer! The department offers all the modern surgical options for the treatment of diseases of the abdominal cavity and blood vessels. The department's doctors have expert knowledge and vast experience in the treatment of colorectal cancer, stomach, esophageal, pancreatic cancers, liver metastases, inflammatory bowel diseases (diverticular disease, Crohn's disease, ulcerative colitis). Also, they specialize in the surgical treatment of vascular pathologies and thyroid diseases.
Department of Abdominal, Thoracic and Vascular Surgery
The Department of Abdominal, Thoracic and Vascular Surgery offers all modern surgical interventions in these fields. Specialization covers the treatment of diseases of the abdominal organs, endocrine glands, pathologies of the lungs and chest wall, pathological vascular lesions of all parts of the body. In addition, kidney transplantation and pancreas transplantation are part of the surgeons' tasks. Whenever possible, operations are performed using minimally invasive techniques that have several advantages over classical interventions.
Department of Adult and Pediatric General, Abdominal, Transplant Surgery
According to Focus magazine, the Department of Adult and Pediatric General, Abdominal, Transplant Surgery ranks among the top German medical facilities specializing in bowel cancer treatment! The department performs surgical treatment of general surgical diseases, abdominal pathologies, and also specializes in organ transplantation. Of particular interest are surgical oncology of the abdominal organs, as well as pancreatic and liver surgery. The department annually performs more than 3,000 surgical interventions, which contributes to its credibility at the national level.
Department of General, Abdominal and Transplant Surgery
According to the Focus magazine, the Department of General, Abdominal and Transplant Surgery ranks among the top German departments specializing in bowel cancer treatment! The department offers the full range of services in these medical fields and guarantees the first-class medical care at the university level. The department specializes in the treatment of diseases of the abdominal cavity, esophagus and thyroid gland, transplantation of liver, kidney and pancreas. The medical facility has won the reputation of one of the three largest and most successful Transplant Centers in Germany. Also, within the clinical practice, doctors hold highly-specialized consultations on rare diseases and provide 24-hour emergency care.
Department of General, Abdominal, Adult and Pediatric Transplant Surgery
According to the Focus magazine, the Department of General, Abdominal, Adult and Pediatric Transplant Surgery ranks among the top German departments specializing in the treatment of bowel cancer! The department specializes in the treatment of tumors of the gastrointestinal tract, pancreas, liver, and retroperitoneal space (peritoneal carcinomatosis), liver, kidney, pancreas, bowel transplantations in children and adults, as well as the surgical treatment of obesity and general surgical interventions.
Department of Adult and Pediatric General, Abdominal, Hepatobiliary, Endocrine, Thoracic and Hernia Surgery
The Department of Adult and Pediatric General, Abdominal, Hepatobiliary, Endocrine, Thoracic and Hernia Surgery offers the full range of services in these fields. The team of the department's surgeons is rightfully proud of their high professionalism and successfully performs operations of varying degrees of complexity for diseases of the thyroid and parathyroid glands, stomach, esophagus, intestines, pancreas, liver, biliary tract, lungs. The medical facility also performs surgery for inguinal, umbilical and incisional hernias. The department has four high-tech operating rooms equipped with advanced surgical instruments, computer systems, devices for intraoperative ultrasound scanning, radiography, etc. Whenever possible, the department's surgeons perform low-traumatic laparoscopic procedures, after which patients need to spend only a few days in the hospital. The department has 100 beds for patient hospitalization.
Department of General, Abdominal and Pediatric Surgery
The Department of General, Abdominal and Pediatric Surgery offers the full range of surgical treatment of diseases of the organs of abdominal cavity, thorax, emergency surgical care in polytrauma, as well as many surgical interventions in children. Of particular interest is cancer surgery on the liver, gallbladder, and pancreas. In addition, the department's specialists masterfully manage all the methods of bariatric surgery. Many operations are performed using minimally invasive techniques, which facilitate the quickest possible recovery of the patient.
Department of General, Abdominal, Endocrine, Colorectal and Bariatric Surgery
According to the Focus magazine, the Department of General, Abdominal, Endocrine, Colorectal and Bariatric Surgery ranks among the top German departments specializing in colon cancer treatment! The department offers the full range of modern surgical interventions. The priority field of clinical activity is cancer surgery, in particular, sparing minimally invasive procedures and robot-assisted interventions. Each patient receives an individual therapy regimen, which is discussed at daily medical boards with doctors from other medical fields. In addition, the responsibility of the medical facility includes surgeries for endocrine disorders and bariatric interventions for morbid obesity. The team of the department's surgeons has a wealth of experience in classical open and minimally invasive procedures on the abdominal organs, as well as specializes in the innovative da Vinci robot-assisted surgery. The department also successfully performs cytoreductive interventions.
Department of General and Abdominal Surgery, Hernia Surgery, Endocrine, Hepatopancreatobiliary, Colorectal, Bariatric, Vascular and Pediatric Surgery
The Department of General and Abdominal Surgery, Hernia Surgery, Endocrine, Hepatopancreatobiliary, Colorectal, Bariatric, Vascular and Pediatric Surgery provides the full range of services in these medical fields. The highly qualified team of the department's surgeons specializes in performing operations of any degree of complexity in the treatment of pathologies of the liver, pancreas, gallbladder, and bile ducts, and diseases of the colon, rectum, and anus, as well as endocrine disorders. The department also performs all modern interventions for vascular pathologies, including aneurysms, carotid stenosis, and intermittent claudication. Patients with morbid obesity can undergo surgical treatment using the most modern and effective techniques. In addition, the medical facility employs experienced pediatric surgeons who provide surgical care to young patients. Operations are performed both on an inpatient and outpatient basis, in accordance with the best recommendations of professional societies. Doctors at the department's state-of-the-art operating rooms perform major interventions, navigation-guided surgery, and minimally invasive surgery to ensure fast recovery of patients.
Department of General and Abdominal Surgery, Hernia Surgery, Colorectal Surgery
According to the Focus magazine, the Department of General and Abdominal Surgery, Hernia Surgery, Colorectal Surgery ranks among the top German medical facilities specializing in the surgical treatment of gallbladder and biliary tract pathologies! The team of the department's surgeons admits patients with benign and malignant gastrointestinal diseases, namely stomach, liver, esophageal, gallbladder and biliary tract, pancreatic, colon and rectal pathologies. The department also carries out treatment for all types of hernias – the medical facility has a quality certificate from the German Hernia Society (DHG). Of particular interest is the resection of malignant tumors of the digestive system. The department's operating rooms have state-of-the-art medical equipment, therefore, in most cases, surgeons can perform interventions without extensive incisions in the skin and soft tissues, but with the use of minimally invasive techniques. Such an approach to surgical treatment greatly facilitates the patient's postoperative recovery process, reduces the risk of complications and excludes severe pain syndrome. The department's surgeons cooperate closely with gastroenterologists, hepatologists, oncologists, radiologists and other doctors from related medical fields. Doctors demonstrate high treatment success rates, use advanced surgical techniques, and observe hygiene and safety standards. Patients can be sure that their health is in the safe hands of leading European specialists.
Department of General Surgery
The Department of General Surgery offers the full range of surgical treatment of diseases of the bowel, liver and other abdominal organs, as well as thyroid gland. In addition, the department performs successful kidney transplantations. The surgeons of the department have at their command advanced medical equipment, therefore, most operations are performed using the very latest minimally invasive techniques. It should be separately noted that the department employs highly qualified specialists, who are well-known not only in Turkey, but also far beyond its borders.
Department of General, Abdominal and Minimally Invasive Surgery
The Department of General, Abdominal and Minimally Invasive Surgery offers the full range of services in these medical fields. The department specializes in the surgical treatment of abdominal organs: esophagus, stomach, small and large intestine, liver, pancreas, gallbladder and bile ducts, thyroid gland. Here are used only proven and sparing surgical treatment methods, which guarantee a rapid recovery of patients.
Cholangiocarcinoma is a dangerous disease with a poor prognosis. The causes of cancer of the bile duct are not known. The disease often develops due to pathologies of the liver, gallbladder, pancreas. The risk factors include alcohol, fatty foods and obesity.
The disease is extremely dangerous. Even in case of early diagnostics, treatment is not always successful. A five-year survival rate in case of detection of pathology at the stage of localized cancer reaches only 13-24% (depending on the location of the primary tumor). Even in developed countries, the overall five-year survival rate is only 8-10%. To get good treatment results, a patient with cancer of the bile duct needs the help of the best doctors in the world.
Is it possible to undergo early diagnostics?
Unfortunately, there are no methods that help detect the early stage of cholangiocarcinoma in a clinically healthy person. In most cases, the disease can be detected only after the onset of symptoms of cancer of the bile duct. This is one of the factors that make it difficult to treat cholangiocarcinoma.
The bile ducts are located deep inside the human body. A tumor sometimes begins to grow directly inside the liver. Due to its small size, the imaging tests cannot recognize this neoplasm. There are also no tumor markers that could be detected in the blood and signal the onset of tumor growth.
Symptoms
In most cases, only the symptoms of cholangiocarcinoma become the reason for the patient's visit to the doctor. The chances of finding a tumor in an asymptomatic stage are extremely low.
The first clinical manifestation is jaundice. It develops as a result of blockage of the bile duct by a tumor. Bile cannot enter the small intestine. Due to this, the feces become white, while the skin becomes yellow, because bile goes into the bloodstream. The patient develops itchy skin and his urine becomes dark because metabolites of bilirubin entering the blood come out with it.
Other symptoms manifest themselves later:
- abdominal pain;
- loss of appetite;
- fever;
- weight loss due to impaired digestion of fats;
- nausea, vomiting.
All symptoms are nonspecific. It is impossible to recognize cancer by them. In addition, cholangiocarcinoma is very rare. In most cases, obstructive jaundice and other clinical signs are caused by other pathological processes (these are mostly caused by gallstone disease).
Diagnostic methods
All patients with jaundice are subject to a thorough diagnostics aimed at the determination of its origin. The tumor can be detected using the following diagnostic methods:
- Ultrasound can be used both as transabdominal ultrasound examination and as more informative endoscopic (with the placement of the sensor in the small intestine) or laparoscopic (placement of the sensor into the abdominal cavity) ultrasound.
- CT, MRI, including with angiography, cholangiography (contrast-enhanced examination of the vessels, biliary tract).
- Endoscopic retrograde cholangiopancreatography involves the introduction of the instrument through the duodenum, contrast-enhanced examination of the biliary tract and X-ray.
- Percutaneous transhepatic cholangiography is an invasive procedure with the injection of a contrast agent into the bile duct using a needle. The next step is X-ray.
- Cholangiography involves the introduction of a tube with a camera in a retrograde manner through the duodenum.
- Laparoscopy involves the introduction of the camera into the abdominal cavity through a small incision in the abdomen.
To confirm a diagnosis, a tumor biopsy is required. It can be done with a needle during cholangiography or cholangioscopy. Sometimes doctors can also perform ultrasound or CT-guided percutaneous biopsy.
Arrangement of diagnostics and treatment
The best hospitals in the world can provide you with highly accurate diagnostics and modern treatment of cholangiocarcinoma using surgery, chemotherapy, radiation therapy and other methods. The foreign specialists perform modern surgical procedures. The Cancer Centers in developed countries have at their disposal high-quality equipment for the diagnostics and treatment of cancer of the bile duct.
The Booking Health company will help you organize your treatment in the best hospitals in the world. There you can undergo an examination, if necessary, receive surgical care or undergo chemotherapy. Our services and benefits:
- Selection of the best hospital, which specialists have achieved the best success in the fight against hepatobiliary malignancies.
- Reduced cost of examination and treatment due to the absence of extra charges and coefficients for foreign patients.
- Preparation of the program taking into account previously performed examinations.
- Appointment with a doctor on dates convenient for you.
- Communication with an attending physician.
- Control of all stages of the program, namely examination, treatment by means of surgery or chemotherapy, rehabilitation.
- Control of invoices and return of unspent funds.
- Communication with the specialists of the Cancer Center after the completion of the program.
- Buying and forwarding of medicines.
- Organization of additional examination, treatment, surgery or rehabilitation abroad.
The company's specialists will provide you with top-class services: booking of the hotel and airline tickets, transfer from the hospital to the airport and back.