Cancer:
Nephroblastoma (Wilms tumor) — Chemotherapy. Treatment abroad

Nephroblastoma is the most common kidney tumor in children. The peak incidence is between 2 and 5 years old. Usually, the lesion affects one kidney, although there are reported cases of a bilateral disease. It is characterized by a high degree of malignancy; in about 10% cases, it is detected with metastases. The treatment of nephroblastomas uses surgical, radiation and medical methods.

Treatment Stages

In most cases, the treatment is initiated with preoperative chemotherapy. Administration of cytotoxic agents allows reducing the tumor size and facilitating the surgical procedures. In the early stages, a combination of vincristine and dactinomycin is used. In the presence of metastases, doxorubicin is also prescribed. The drug treatment takes 4 to 6 weeks.

The surgical procedure scope is determined by nephroblastoma size. Sometimes, chemotherapy allows reducing the tumor mass so that the organ-preserving surgery becomes possible. The surgeon removes a part of the kidney affected by cancer only. After a few years, thanks to the ability to regenerate, the preserved organ is restored to normal size.

Upon significant lesions, the kidney is removed entirely, together with the adrenal gland, when required. During surgery, the physician carefully examines the liver, adjacent lymph nodes and peritoneum for the presence of metastases. The suspicious tissue is also excised or biopsied.

Upon bilateral disease, the oncologist develops an individual treatment strategy, which will allow maintaining the functions of at least one kidney.

After surgery, the repeated chemotherapy is prescribed to destroy the residual tumor. Depending on the disease stage, a combination of 2 or 3 cytotoxic drugs with different mechanisms of action is administered again. The treatment duration can range from 1 to 8 months.

Some patients are also prescribed the radiation therapy (e.g., in the presence of metastasis or incomplete tumor removal). In childhood, a proton therapy is preferred, which allows a focused influence on the pathological focus without compromising the healthy tissues.

The operated area and lung metastases, when required, are subjected to irradiation. The procedures are carried out on an outpatient basis every day, from Monday to Friday. One session takes 15 to 20 minutes. The treatment course can take 1 to 6 weeks.

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University Hospital Bonn

8.6/10 from 150 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The key objective of the Department of Internal Medicine III is to create and offer optimal treatments for internal diseases on inpatient, partially inpatient and outpatient basis.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Bonn

Price 7178.00

University Hospital Cologne

8.7/10 from 82 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department I for Internal Medicine of the University Hospital Cologne deals with the treatment of patients with various internal diseases. This includes in particular the following fields: Oncology, Hematology, Clinical infectology, Clinical immunology, Hemostasis, Intensive care.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Cologne

Price 6973.00

University Hospital Frankfurt

7.5/10 from 97 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Hematology, Oncology, Hemostasis, Rheumatology and Infectology at the University Hospital Frankfurt specializes in the treatment of all diseases of the hymatopoietic system and solid tumors.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 8342.00

Charite University Hospital Berlin

9/10 from 95 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Charité Comprehensive Cancer Center integrates the clinical and research activities for all Charité departments and institutes dealing with Cancer. The director of the Charité Comprehensive Cancer Center is Prof. Dr. med. Ulrich Keilholz.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Berlin

Price 10116.00

University Hospital Heidelberg

9/10 from 57 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Hematology, Oncology and Rheumatology at the Heidelberg University Hospital makes every effort to provide medical care of the highest quality to the patients with oncologic and rheumatologic diseases.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Heidelberg

Krankenhaus Nordwest

9.5/10 from 24 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

Department of Oncology and Hematology of Krankenhaus Nordwest offers a wide range of medical services, including diagnosis, therapy and treatment of oncological diseases or diseases closely associated with the circulatory system.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Frankfurt am Main

Price 6437.00

Städtisches Klinikum Schwabing

8.5/10 from 7 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Hematology, Oncology, Immunology, Palliative Medicine, Infectious Diseases and Tropical Medicine in Schwabing treats all benign blood diseases, disorders of the immune and coagulation system, all forms of blood cancer, and the most of cancers.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 6477.00

RWTH University Hospital Aachen

8.7/10 from 41 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Oncology, Hematology and Stem Cell Transplant provides patient care on both inpatient and outpatient basis. The focuses of the inpatient treatment are acute leukemia and high-dose chemotherapy followed by autologous blood stem cell transplantation.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Aachen

Price 6414.00

Alfried Krupp Hospital in Essen-Ruettenscheid

9.9/10 from 42 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The main treatment areas of the Department of Internal Medicine I, headed by Prof. Dr. med. Thomas Budde, are invasive and non-invasive cardiac diagnostics and therapy of all cardiac diseases.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Essen

Price 6096.00

University Hospital Dusseldorf

9.9/10 from 71 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Hematology, Oncology and Clinical Immunology at the University Hospital Dusseldorf provides treatment of patients with blood diseases, cancer and immune system diseases. The Department focuses on the treatment of malignant diseases of  blood, bone marrow and lymph nodes. .


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Duesseldorf

Price 8108.00

Hannover Medical School, MHH

9.8/10 from 43 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The clinic of hematology, hemostasis, oncology and stem cell transplantation is a leading therapeutic clinic of the Medical Institute of Hannover for patients with solid tumor and systemic diseases, with other partially benign diseases of the hematopoietic system, as well as bleeding disorders.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Hannover

Price 7207.00

Städtisches Klinikum Neuperlach

9.8/10 from 11 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The department of hematology and oncology diagnosed and treated malignant tumors. The therapeutic spectrum includes all medicamentous treating methodes including chemotherapy, antibody, immune and hormone therapy. Cancer patients benefit from interdisciplinary treatment.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Munich

Price 6581.00

Gummersbach District Hospital of the Klinikum Oberberg

9.6/10 from 23 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Internal Medicine II at the Klinikum Oberberg in Gummersbach focuses on diagnosis and treatment of oncological and hematological diseases.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Gummersbach

Price 5873.00

Salem-Spital

9.6/10 from 29 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

Specialists in Department of Oncology of Salem-Spital are also involved in Swiss Tumor Institute STI. Among our partners there is a competenct network that offers real advantages in diagnosis and therapy of tumors and treats patients as the focus of its work.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Switzerland
location_searchingCity: Bern

University Hospital Halle (Saale)

9.5/10 from 78 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Internal Medicine IV (Hematology and Oncology) covers the whole range of hematology and oncology. This includes prevention, diagnosis, therapy and post-operative care for cancer of all organs and blood.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Halle

Price 7106.00

St. Anna Hospital Herne

9.5/10 from 7 Votes

Chemotherapy of Nephroblastoma (Wilms tumor) (1 course)

The Department of Gastroenterology specializes in: Treatment of gastrointestinal diseases Hepatology Endoscopy, ultrasound, gastroenterological diagnostics Diabetology Oncology Treatment of infectious diseases.


Duration 7 days
Type of Treatment: Inpatient
location_onCountry: Germany
location_searchingCity: Herne

Price 6632.00