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Allogeneic bone marrow transplantation in acute myeloid leukemia (253489) | University Hospital Giessen UKGM - BookingHealth
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After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.<\/p>\n\n<p style=\"text-align: justify;\">Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.<\/p>\n\n<p style=\"text-align: justify;\"><strong>Before the procedure<\/strong>, you will receive chemotherapy, if necessary in combination with radiation therapy. 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The rehabilitation period can last from 1 to 2 months.<\/p>\n\n<p style=\"text-align: justify;\">When your complete blood count returns to normal, your doctor will schedule your <strong>discharge from the department<\/strong>. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. 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Allogeneic bone marrow transplantation in acute myeloid leukemia in University Hospital Giessen UKGM

University Hospital Giessen UKGM

Giessen, Germany
Program id # 253489
Doctor photo
Prof. Dr. Dr. med. Friedrich Grimminger
Department of Oncology, Hematology and Palliative Care
Specialized in: oncology, hematology, palliative care

The program includes:

  • Initial presentation in the clinic
  • case history collection
  • general clinical examination
  • laboratory tests:
    • complete blood count
    • biochemical analysis of blood
    • TSH-basal, fT3, fT4
    • differential blood count
    • inflammation indicators (CRP, ESR)
    • indicators of blood coagulation
  • abdominal ultrasound scan
  • CT/MRI scans of the whole body
  • needle biopsy of the bone marrow with histological:
    • cytochemistry
    • immunocytology
    • cytogenetics (Philadelphia
      chromosome detection)
    • molecular biology
  • biopsy and histological examination of CSF
  • examination by experts of:
    • cardiology
    • otolaryngology
    • immunology
    • ophthalmology
  • registration in the European bone marrow donor base
  • conducting high-dose chemotherapy
  • allogeneic bone marrow transplantation from
    unrelated donor
  • isolation by neutropenic precautions
  • symptomatic treatment
  • control examinations
  • the cost of essential medicines and materials
  • nursing services
  • full hospital accommodation
  • explanation of future recommendations

How program is carried out

During the first visit, the doctor will conduct a clinical examination and go through the results of the available diagnostic tests. After that, you will undergo the necessary additional examination, such as the assessment of liver and kidney function, ultrasound scan, CT scan and MRI.

Also, the doctor will conduct a bone marrow biopsy followed by cytological examination of the harvested material. This will help him to determine the histological features of your bone marrow (in particular, identify HLA system antigens) and select a suitable donor. The donor can be a family member or a person from the bone marrow registry. In the second case, the donor material is stored in a bone marrow bank.

Before the procedure, you will receive chemotherapy, if necessary in combination with radiation therapy. The course of chemo- or chemoradiation therapy lasts from 2 to 8 days.

The bone marrow transplant procedure is an intravenous infusion, i.e. the healthy bone marrow will be injected through a catheter, intravenously. You will stay in your room during the procedure. A bone marrow transplant is completely painless and does not require anesthesia.

During the period of healthy bone marrow engraftment, you will stay in a sterile ward. This is a necessary precaution because during this time your immune system is very weak and cannot withstand environmental pathogens. The risk of bleeding is also quite high, so you will be advised to avoid mechanical damage.

A relative or other close person may stay in the ward with you. You will not be allowed to go outside the department and leave your ward often. The rehabilitation period can last from 1 to 2 months.

When your complete blood count returns to normal, your doctor will schedule your discharge from the department. You will receive information about the rules that you will need to follow at home, the frequency and type of control examinations, and subsequent treatment measures. You will also receive a detailed medical report, which will reflect the entire course of treatment.

Required documents

  • Medical records
  • MRI/CT scan (not older than 3 months)
  • Bone marrow biopsy results (if available)

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About the department

The Department of Oncology, Hematology and Palliative Care at the University Hospital Giessen UKGM offers all the options of modern medicine for the treatment of patients with the pathologies in these fields. Specialization covers the treatment of cancer of the internal organs, blood cancer, symptomatic treatment of progressive incurable diseases. Other focuses of the department are intensive care medicine and special pain therapy. To achieve successful and long-term results, the clinical practice is based on the use of effective classic and innovative treatment methods. The department is headed by Prof. Dr. Dr. med. Friedrich Grimminger.

The department's oncologists take care of the health of patients with malignant diseases of all organs. The department is part of the Interdisciplinary Cancer Center, within which all experts from related fields work for the benefit of patients. The individual and optimal treatment regimens are developed at interdisciplinary tumor boards. The treatment is carried out in accordance with national and international protocols of professional societies. The patients with terminal stages of the disease are provided with all the necessary palliative care measures, which helps to alleviate symptoms and improve the quality of life.

Another department’s priority is the treatment of patients with malignant diseases of the hematopoietic and lymphatic systems. Of particular interest is the treatment of malignant lymphomas, acute and chronic leukemias and myeloproliferative disorders. The spectrum is also complemented by therapy for blood-clotting disorders, such as immune thrombocytopenia.

The department's range of medical services includes:

  • Diagnostics and treatment of oncological diseases of internal organs
    • Respiratory system cancers
      • Lung cancer
      • Pleural cancer
    • Gastrointestinal cancers
      • Bowel cancer
      • Rectal cancer
      • Esophageal carcinoma
      • Stomach cancer
      • Pancreatic cancer
      • Liver cancer
    • Head and neck tumors 
      • Primary brain tumors
      • Tumors of the lips, mouth and oropharynx
      • Laryngeal cancer
      • Thyroid cancer
    • Gynecological tumors
      • Breast cancer
      • Ovarian cancer
      • Uterine cancer
      • Cervical cancer
    • Urological tumors
      • Prostate cancer
      • Kidney cancer
      • Bladder cancer
    • Rare tumors
      • Sarcomas
      • Melanomas
  • Diagnostics and treatment of hematological diseases
    • Acute lymphocytic leukemia
    • Acute myeloid leukemia
    • Amyloidosis
    • Aplastic anemia
    • Chronic lymphocytic leukemia
    • Chronic myeloid leukemia
    • Essential thrombocythemia
    • Hairy cell leukemia
    • Hemoglobinopathies
    • Hemolytic anemia
    • Hodgkin's lymphoma
    • Immune thrombocytopenia
    • Multiple myeloma
    • Myelodysplastic syndrome
    • Non-Hodgkin’s lymphoma
    • Polycythemia vera
    • Osteomyelosclerosis
  • Palliative care for patients at the terminal stage of cancer aimed at alleviating symptoms and improving quality of life
  • Other medical services

Curriculum vitae

Prof. Friedrich Grimminger studied medicine at the Justus Liebig University Giessen. He also completed a semester at the British Universities of Newcastle and Edinburgh (Chemistry and Biology). In 1989, he received his doctorate in Human Medicine, and in 1990 also received a diploma in Biology. Two years later, he had his habilitation in Human Medicine at the Justus Liebig University Giessen. In 1994, Prof. Grimminger had his board certification in Internal Medicine with a focus on Pulmonology, Oncology, Intensive Care, Palliative Care and Pain Therapy. He is a Honorary Professor at the Universities of Kent (Canterbury, UK) and Texas, USA.

Photo of the doctor: (c) UKGM - Universitätsklinikum Gießen und Marburg GmbH


About hospital

The University Hospital Giessen UKGM positions itself as an ultramodern medical facility with outstanding quality of medical care. The hospital presents almost all areas of medicine, ranging from ophthalmology to traumatology and dentistry. The priorities of the hospital’s activities include surgery, neurosurgery, oncology, nephrology with kidney transplantation and pediatric medicine.

The hospital is the third largest in Germany. Every year, more than 436,000 patients are treated in two locations of the hospital (Giessen and Marburg): 342,000 outpatients and 94,000 inpatients. The medical facility is the first privatized university hospital in the country.

The hospital staff is engaged not only in clinical practice, but also in research activities on the basis of the Faculty of Medicine at Justus Liebig University Giessen and Philipps University of Marburg, which contributes to a significant contribution to the development of modern medicine. During the many years of productive work on the development of new diagnostic and treatment methods, the hospital’s doctors managed to make many significant discoveries.

The hospital enjoys an excellent reputation in Germany and far beyond its borders. It managed to gain such credibility thanks to the high competence of doctors, advanced equipment, high-quality medical service and care.

Photo: (c) depositphotos

Accommodation in hospital

Patients rooms

The patients of the University Hospital Giessen UKGM live in comfortable rooms made in a modern design and light colors. Each room has an ensuite bathroom with shower and toilet. The standard room furnishing includes an automatically adjustable bed, a bedside table, a wardrobe, a table and chairs for receiving visitors, a TV, a telephone.

Meals and Menus

The patients of the hospital are offered balanced, healthy three meals a day: buffet breakfast, lunch and dinner. The private kitchen, certified according to DIN EN ISO 9001:2000, is responsible for providing patients with food and drinks.

If for some reason you do not eat all foods, you will be offered an individual menu. The hospital also has a cafeteria with a large assortment of hot and cold drinks, snacks and desserts.

Further details

Standard rooms include:

Toilet
Shower
Wi-Fi
TV

Television

All patient rooms are equipped with TV sets. If you have some questions, please contact medical personnel.

Religion

Religious services can be provided upon request.

Accompanying person

During an inpatient program, an accompanying person can stay with you in a patient room or in a hotel of your choice.

Hotel

During the outpatient program, you can stay at the hotel of your choice. Our managers will help you to choose the most suitable option.